Search Results - (Author, Cooperation:T. J. O'Brien)

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  1. 1
    Staff View
    Publication Date:
    2014-10-09
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    A. S. Allen ; S. F. Berkovic ; P. Cossette ; N. Delanty ; D. Dlugos ; E. E. Eichler ; M. P. Epstein ; T. Glauser ; D. B. Goldstein ; Y. Han ; E. L. Heinzen ; Y. Hitomi ; K. B. Howell ; M. R. Johnson ; R. Kuzniecky ; D. H. Lowenstein ; Y. F. Lu ; M. R. Madou ; A. G. Marson ; H. C. Mefford ; S. Esmaeeli Nieh ; T. J. O'Brien ; R. Ottman ; S. Petrovski ; A. Poduri ; E. K. Ruzzo ; I. E. Scheffer ; E. H. Sherr ; C. J. Yuskaitis ; B. Abou-Khalil ; B. K. Alldredge ; J. F. Bautista ; A. Boro ; G. D. Cascino ; D. Consalvo ; P. Crumrine ; O. Devinsky ; M. Fiol ; N. B. Fountain ; J. French ; D. Friedman ; E. B. Geller ; S. Glynn ; S. R. Haut ; J. Hayward ; S. L. Helmers ; S. Joshi ; A. Kanner ; H. E. Kirsch ; R. C. Knowlton ; E. H. Kossoff ; R. Kuperman ; S. M. McGuire ; P. V. Motika ; E. J. Novotny ; J. M. Paolicchi ; J. M. Parent ; K. Park ; R. A. Shellhaas ; J. J. Shih ; R. Singh ; J. Sirven ; M. C. Smith ; J. Sullivan ; L. Lin Thio ; A. Venkat ; E. P. Vining ; G. K. Von Allmen ; J. L. Weisenberg ; P. Widdess-Walsh ; M. R. Winawer
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-08-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Child Development Disorders, Pervasive ; Cohort Studies ; Exome/genetics ; Female ; Fragile X Mental Retardation Protein/metabolism ; Genetic Predisposition to Disease/genetics ; Humans ; Infant ; Intellectual Disability/*genetics/physiopathology ; Lennox Gastaut Syndrome ; Male ; Mutation/*genetics ; Mutation Rate ; N-Acetylglucosaminyltransferases/genetics ; Probability ; Receptors, GABA-A/genetics ; Spasms, Infantile/*genetics/physiopathology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    O'Brien, T. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-4632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    O'Brien, T J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Imidazolidinyl urea is a preservative used commonly in cosmetics. Although there have been few reports of contact sensitivity, it does seem to be an important contact allergen. Sensitivity should be considered in any woman with dermatitis of the face.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    O'Brien, T. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1987
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    O'Brien, T. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1986
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Photoallergic dermatitis due to musk ambrette is reported in six patients, and the literature on this sensitivity is reviewed. The condition presents with a typical pattern involving the neck and cheeks, and the diagnosis can be confirmed by photopatch testing with musk ambrette.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    O'Brien, T. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1986
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Czarnecki, D. B. ; Rotstein, H. ; O'Brien, T. J. ; Lyall, I. G. ; Hanna, M. J. D.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The sign of Leser-Trélat is the sudden appearance and rapid increase in number of seborrhoeic keratoses on previously normal skin. It is a cutaneous marker of internal malignancy. Two patients exhibiting this sign are described and a further thirty-seven have been found in the medical literature. The main features of these patients are reviewed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    O'Brien, T. J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Rotstein, H. ; Butler, J. M. ; Czarnecki, D. B. ; O'Brien, T. J. ; George, M. T.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1980
    Staff View
    ISSN:
    1440-0960
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Twenty patients with mycosis fungoides were treated with photochemotherapy using oral psoralens and long wave ultraviolet light (PUVA) over a two-year period. PUVA was effective in producing a diminution of cutaneous deposits of mycosis fungoides with each clinical pattern of presentation. In most patients complete clearing could not be achieved, and in those considered free of disease, sustained total clearing off PUVA could not be maintained. Lack of response to the effect of PUVA if reinstituted for recurrence of disease did not occur.The palliative use of PUVA for the treatment of mycosis fungoides is recommended.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    O'Brien, T. J. ; Greaves, M. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    O'Brien, T. J. ; Greaves, M. W.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1365-2133
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Nova outbursts take place in binary star systems comprising a white dwarf and either a low-mass Sun-like star or, as in the case of the recurrent nova RS Ophiuchi, a red giant. Although the cause of these outbursts is known to be thermonuclear explosion of matter transferred from the companion ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Lloyd, H. M. ; O'Brien, T. J. ; Bode, M. F. ; Predehl, P. ; Schmitt, J. H. M. M. ; Trümper, J. ; Watson, M. G. ; Pounds, K. A.

    [s.l.] : Nature Publishing Group
    Published 1992
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Nova Herculis 1991 was discovered independently by United Kingdom and Japanese amateur astronomers6 on 1991 March 24-25. Estimated visual magnitudes of V ~ 5 at discovery suggest that Nova Her 1991 is one of the brightest novae at optical maximum of recent decades. It is unclear whether the nova ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    1432-1203
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Summary The gene for superoxide dismutase-1 (SOD-1) is clearly on chromosome 21, although there is disagreement on the precise band location of SOD-1 on the long (q) arm of number 21. We report a patient with normal superoxide dismutase-1 (SOD-1) activity and an interstitial deletion of chromosome 21 resulting in monosomy for band q21. His phenotype is characterized by moderate mental retardation, a long narrow face, high and arched palate, cardiac murmur, undescended testes, and long hyperflexible extremities. The normal SOD-1 activity supports localization of this enzyme to 21q22.1.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    O'Brien, T. J. ; Lloyd, H. M.
    Springer
    Published 1994
    Staff View
    ISSN:
    1572-946X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract We present a simple model for interactions between the slow and fast phases of mass ejection in classical nova outbursts. A situation develops in which a layer of hot gas sandwiched between two shocks progresses through the slow wind until it ‘blows-out’, expanding and cooling adiabatically. We calculate the X-ray emission from this model and find that the dynamical timescale is at least as important as the radiative cooling time in determining the form of the X-ray light curves. Models of this type may help to explain the origin of X-ray emission in some classical nova outbursts.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Lloyd, H. M. ; O'Brien, T. J. ; Bode, M. F. ; Kahn, F. D.
    Springer
    Published 1994
    Staff View
    ISSN:
    1572-946X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Bipolarity is a common feature in the outbursts of classical, recurrent and symbiotic novae. In this paper, we present the results of numerical calculations of bipolar explosions in which two parcels of gas are ejected at highly supersonic and oppositely directed velocities into a cold surrounding medium. The calculations demonstrate the formation of a dense ring of shocked material in the plane normal to the line of ejection, due to the interaction of two bowshocks. Observational candidates for this hydrodynamic phenomenon are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Lloyd, H. M. ; O'Brien, T. J. ; Bode, M. F.
    Springer
    Published 1995
    Staff View
    ISSN:
    1572-946X
    Keywords:
    Novae ; Numerical Hydrodynamics
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Classical nova outbursts occur in binary systems containing a white dwarf accretor and a Roche-lobe-filling main-sequence star. The outburst is due to a thermonuclear runaway in the accreted material on the surface of the white dwarf, and results in the ejection of up to 10−4 M ⊙of material at velocities of several hundred to a few thousand kilometres per second. There is now strong evidence that the mass ejection takes place via a wind with secularly increasing velocity. The fast ejecta catches up with slower moving material ejected earlier in the outburst, forming a layer of shock-heated gas which gives rise to a short burst of soft X-ray emission. This emission was observed in V838 Her (Nova Herculis 1991), and was succesfully accounted for by the ‘interacting winds’ model. In this paper, we present 2.5-D numerical hydrodynamics calculations of interacting winds in novae which consider the effects of the binary system on shaping the mass-loss, and show that many of the features seen in the optical shells of novae many years after outburst can be accounted for.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses