Search Results - (Author, Cooperation:T. Hashimoto)
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1Latest Papers from Table of Contents or Articles in PressD. Kahl, H. Yamaguchi (山口英斉), S. Kubono (久保野茂), A. A. Chen, A. Parikh, D. N. Binh, J. Chen (陈俊), S. Cherubini, N. N. Duy, T. Hashimoto (橋本尚志), S. Hayakawa (早川勢也), N. Iwasa (岩佐直仁), H. S. Jung (정효순), S. Kato (加藤静吾), Y. K. Kwon (권영관), S. Nishimura (西村俊二), S. Ota (大田晋輔), K. Setoodehnia, T. Teranishi (寺西高), H. Tokieda (時枝紘史), T. Yamada (山田拓), C. C. Yun (윤종철), and L. Y. Zhang (张立勇)
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-01-04Publisher: American Physical Society (APS)Print ISSN: 0556-2813Electronic ISSN: 1089-490XTopics: PhysicsKeywords: Nuclear AstrophysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-16Publisher: Wiley-BlackwellPrint ISSN: 0007-0963Electronic ISSN: 1365-2133Topics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressA. R. Forrest ; H. Kawaji ; M. Rehli ; J. K. Baillie ; M. J. de Hoon ; V. Haberle ; T. Lassmann ; I. V. Kulakovskiy ; M. Lizio ; M. Itoh ; R. Andersson ; C. J. Mungall ; T. F. Meehan ; S. Schmeier ; N. Bertin ; M. Jorgensen ; E. Dimont ; E. Arner ; C. Schmidl ; U. Schaefer ; Y. A. Medvedeva ; C. Plessy ; M. Vitezic ; J. Severin ; C. Semple ; Y. Ishizu ; R. S. Young ; M. Francescatto ; I. Alam ; D. Albanese ; G. M. Altschuler ; T. Arakawa ; J. A. Archer ; P. Arner ; M. Babina ; S. Rennie ; P. J. Balwierz ; A. G. Beckhouse ; S. Pradhan-Bhatt ; J. A. Blake ; A. Blumenthal ; B. Bodega ; A. Bonetti ; J. Briggs ; F. Brombacher ; A. M. Burroughs ; A. Califano ; C. V. Cannistraci ; D. Carbajo ; Y. Chen ; M. Chierici ; Y. Ciani ; H. C. Clevers ; E. Dalla ; C. A. Davis ; M. Detmar ; A. D. Diehl ; T. Dohi ; F. Drablos ; A. S. Edge ; M. Edinger ; K. Ekwall ; M. Endoh ; H. Enomoto ; M. Fagiolini ; L. Fairbairn ; H. Fang ; M. C. Farach-Carson ; G. J. Faulkner ; A. V. Favorov ; M. E. Fisher ; M. C. Frith ; R. Fujita ; S. Fukuda ; C. Furlanello ; M. Furino ; J. Furusawa ; T. B. Geijtenbeek ; A. P. Gibson ; T. Gingeras ; D. Goldowitz ; J. Gough ; S. Guhl ; R. Guler ; S. Gustincich ; T. J. Ha ; M. Hamaguchi ; M. Hara ; M. Harbers ; J. Harshbarger ; A. Hasegawa ; Y. Hasegawa ; T. Hashimoto ; M. Herlyn ; K. J. Hitchens ; S. J. Ho Sui ; O. M. Hofmann ; I. Hoof ; F. Hori ; L. Huminiecki ; K. Iida ; T. Ikawa ; B. R. Jankovic ; H. Jia ; A. Joshi ; G. Jurman ; B. Kaczkowski ; C. Kai ; K. Kaida ; A. Kaiho ; K. Kajiyama ; M. Kanamori-Katayama ; A. S. Kasianov ; T. Kasukawa ; S. Katayama ; S. Kato ; S. Kawaguchi ; H. Kawamoto ; Y. I. Kawamura ; T. Kawashima ; J. S. Kempfle ; T. J. Kenna ; J. Kere ; L. M. Khachigian ; T. Kitamura ; S. P. Klinken ; A. J. Knox ; M. Kojima ; S. Kojima ; N. Kondo ; H. Koseki ; S. Koyasu ; S. Krampitz ; A. Kubosaki ; A. T. Kwon ; J. F. Laros ; W. Lee ; A. Lennartsson ; K. Li ; B. Lilje ; L. Lipovich ; A. Mackay-Sim ; R. Manabe ; J. C. Mar ; B. Marchand ; A. Mathelier ; N. Mejhert ; A. Meynert ; Y. Mizuno ; D. A. de Lima Morais ; H. Morikawa ; M. Morimoto ; K. Moro ; E. Motakis ; H. Motohashi ; C. L. Mummery ; M. Murata ; S. Nagao-Sato ; Y. Nakachi ; F. Nakahara ; T. Nakamura ; Y. Nakamura ; K. Nakazato ; E. van Nimwegen ; N. Ninomiya ; H. Nishiyori ; S. Noma ; T. Noazaki ; S. Ogishima ; N. Ohkura ; H. Ohimiya ; H. Ohno ; M. Ohshima ; M. Okada-Hatakeyama ; Y. Okazaki ; V. Orlando ; D. A. Ovchinnikov ; A. Pain ; R. Passier ; M. Patrikakis ; H. Persson ; S. Piazza ; J. G. Prendergast ; O. J. Rackham ; J. A. Ramilowski ; M. Rashid ; T. Ravasi ; P. Rizzu ; M. Roncador ; S. Roy ; M. B. Rye ; E. Saijyo ; A. Sajantila ; A. Saka ; S. Sakaguchi ; M. Sakai ; H. Sato ; S. Savvi ; A. Saxena ; C. Schneider ; E. A. Schultes ; G. G. Schulze-Tanzil ; A. Schwegmann ; T. Sengstag ; G. Sheng ; H. Shimoji ; Y. Shimoni ; J. W. Shin ; C. Simon ; D. Sugiyama ; T. Sugiyama ; M. Suzuki ; N. Suzuki ; R. K. Swoboda ; P. A. t Hoen ; M. Tagami ; N. Takahashi ; J. Takai ; H. Tanaka ; H. Tatsukawa ; Z. Tatum ; M. Thompson ; H. Toyodo ; T. Toyoda ; E. Valen ; M. van de Wetering ; L. M. van den Berg ; R. Verado ; D. Vijayan ; I. E. Vorontsov ; W. W. Wasserman ; S. Watanabe ; C. A. Wells ; L. N. Winteringham ; E. Wolvetang ; E. J. Wood ; Y. Yamaguchi ; M. Yamamoto ; M. Yoneda ; Y. Yonekura ; S. Yoshida ; S. E. Zabierowski ; P. G. Zhang ; X. Zhao ; S. Zucchelli ; K. M. Summers ; H. Suzuki ; C. O. Daub ; J. Kawai ; P. Heutink ; W. Hide ; T. C. Freeman ; B. Lenhard ; V. B. Bajic ; M. S. Taylor ; V. J. Makeev ; A. Sandelin ; D. A. Hume ; P. Carninci ; Y. Hayashizaki
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Atlases as Topic ; Cell Line ; Cells, Cultured ; Cluster Analysis ; Conserved Sequence/genetics ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genes, Essential/genetics ; Genome/genetics ; Humans ; Mice ; *Molecular Sequence Annotation ; Open Reading Frames/genetics ; Organ Specificity ; Promoter Regions, Genetic/*genetics ; RNA, Messenger/analysis/genetics ; Transcription Factors/metabolism ; Transcription Initiation Site ; Transcription, Genetic/genetics ; Transcriptome/*geneticsPublished by: -
4Latest Papers from Table of Contents or Articles in PressT. Noguchi ; T. Nakamura ; M. Kimura ; M. E. Zolensky ; M. Tanaka ; T. Hashimoto ; M. Konno ; A. Nakato ; T. Ogami ; A. Fujimura ; M. Abe ; T. Yada ; T. Mukai ; M. Ueno ; T. Okada ; K. Shirai ; Y. Ishibashi ; R. Okazaki
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-05-07Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Clinical trials (epidemiology), Open access, NeurologyPublished by: -
6Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-05-22Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Quantum informationPublished by: -
7Latest Papers from Table of Contents or Articles in PressUmemoto, T., Hashimoto, M., Matsumura, T., Nakamura-Ishizu, A., Suda, T.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-08-07Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: Stem Cells & RegenerationPublished by: -
8Latest Papers from Table of Contents or Articles in PressJ. Carolan ; C. Harrold ; C. Sparrow ; E. Martin-Lopez ; N. J. Russell ; J. W. Silverstone ; P. J. Shadbolt ; N. Matsuda ; M. Oguma ; M. Itoh ; G. D. Marshall ; M. G. Thompson ; J. C. Matthews ; T. Hashimoto ; J. L. O'Brien ; A. Laing
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-07-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
9Latest Papers from Table of Contents or Articles in PressB. Hatsukade ; K. Ohta ; A. Endo ; K. Nakanishi ; Y. Tamura ; T. Hashimoto ; K. Kohno
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-06-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
10Latest Papers from Table of Contents or Articles in PressT. Hashimoto ; T. Perlot ; A. Rehman ; J. Trichereau ; H. Ishiguro ; M. Paolino ; V. Sigl ; T. Hanada ; R. Hanada ; S. Lipinski ; B. Wild ; S. M. Camargo ; D. Singer ; A. Richter ; K. Kuba ; A. Fukamizu ; S. Schreiber ; H. Clevers ; F. Verrey ; P. Rosenstiel ; J. M. Penninger
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Biocatalysis ; Colitis/drug therapy/*etiology/*microbiology/pathology ; Dextran Sulfate ; Diarrhea/complications ; Dietary Proteins/metabolism/pharmacology ; Female ; Gene Deletion ; Genetic Predisposition to Disease ; Germ-Free Life ; Homeostasis ; Immunity, Innate ; Intestines/*microbiology/pathology ; Male ; Malnutrition/*complications/metabolism ; *Metagenome ; Mice ; Models, Biological ; Niacinamide/metabolism/pharmacology/therapeutic use ; Peptidyl-Dipeptidase A/deficiency/genetics/*metabolism ; Renin-Angiotensin System/physiology ; TOR Serine-Threonine Kinases/metabolism ; Trinitrobenzenesulfonic Acid ; Tryptophan/*metabolism/pharmacology/therapeutic usePublished by: -
11Latest Papers from Table of Contents or Articles in PressFlötotto, D., Ota, Y., Bai, Y., Zhang, C., Okazaki, K., Tsuzuki, A., Hashimoto, T., Eckstein, J. N., Shin, S., Chiang, T.-C.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-28Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
12Latest Papers from Table of Contents or Articles in PressZhang, P., Yaji, K., Hashimoto, T., Ota, Y., Kondo, T., Okazaki, K., Wang, Z., Wen, J., Gu, G. D., Ding, H., Shin, S.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-13Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: PhysicsPublished by: -
13Latest Papers from Table of Contents or Articles in PressN. Yamanaka, S. Hashimoto, T. Kaneko, and H. Ohki (JLQCD Collaboration)
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-09-26Publisher: American Physical Society (APS)Print ISSN: 0556-2821Electronic ISSN: 1089-4918Topics: PhysicsKeywords: Lattice field theories, lattice QCDPublished by: -
14Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-11-09Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: -
15Articles: DFG German National LicensesMotowoka, M. ; Jinnai, H. ; Hashimoto, T. ; Qiu, Y. ; Han, C. C.
College Park, Md. : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Early stage of spinodal decomposition kinetics of deuterated polycarbonate/poly(methylmethacrylate) blend has been studied by the time resolved small angle neutron scattering measurements. A trapped miscible state was obtained through fast solution casting of film specimens. Time dependence of the structure factor, S(q,t), was measured after the specimen temperature was quickly increased to a final temperature which is above its glass transition temperature, Tg. Thus, the early stage of spinodal decomposition kinetics has been observed starting from the dimension (q−1) comparable to the single chain radius of gyration, Rg, for a binary polymer mixture. The results provide an unequivocal quantitative measure of the virtual structure factor, S(q,∞); the relationship of qm and qc through rate of growth, Cahn-plot analysis, and singularity in S(q,∞); the growth of fluctuation of qRg〈1 and intrachain relaxation of qRg(approximately-greater-than)1; and also a clear proof of the Cahn–Hillard–Cook theory in the early stage of spinodal decomposition of a mean-field system.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesHashimoto, T. ; Katakura, S. ; Edagawa, K.
[S.l.] : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: An apparatus for deformation of solids in liquid 3He is constructed. Either tensile deformation or compression of a specimen can be performed by exchanging the assemblies in the 3He pot which has a capacity of about 30 cm3. The pulling rod for transmitting load from the tensile testing machine to the specimen runs inside the outlet tube of 3He, being isolated from 4He bath and almost free from mechanical friction. To measure the change in flow stress with the supernormal transition of superconducting metals, a superconducting magnet is mounted outside of the vacuum chamber which separates the 3He pot and the 4He bath. Under an applied load for plastic deformation the system is stably operative down to 0.6 K, while the lowest temperature achieved is 0.5 K. Some results on Ta and NaCl are presented. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesFujii, Y ; T, Shimada ; Koitabashi, A ; Hashimoto, T ; Hosaka, K ; Tabei, K ; Namatame, T ; Yoneda, M ; Hiraishi, H ; Terano, A
Oxford, UK; Malden, USA : Blackwell Science Inc
Published 2005Staff ViewISSN: 1524-475XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Aim: Trefoil factor family (TFF) peptides are known to facilitate wound healing in gastric mucosa. However, the regulatory mechanisms of gastric TFF expression are not fully understood yet. In this study, we examined the effect of TNF-α on TFF1 and TFF2 expression in gastric epithelial cells.Methods: MKN45 cells were used. TFF mRNA expression was analyzed by real-time quantitative RT-PCR. Promoter sequences of TFF1 gene (−956 to +36) and TFF2 gene (−912 to +24) were inserted into pGL3 vector and reporter gene assays were performed. NF-κB activity was monitored by using a NF-κB responsive element-driven reporter vector.Results: (1) TNF-α(0.1–30 ng/ml) down-regulated TFF1 and TFF2 mRNA expression in a dose-dependent manner. (2) Reporter gene assays also confirmed the down-regulation of TFF1 and TFF2 gene transcription by TNF-α. (3) TNF-α activated NF-κB. (4) Overexpression of dominant negative IκBα prevented both TNF-α-induced NF-κB activation and TNF-α-induced down-regulation of TFF expression.Conclusions: TNF-α down-regulates gastric TFF expression through NF-κB pathway, suggesting that TFF expression is sensitive to inflammatory stimuli.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesYokoo, K ; Aoyama, H ; Tamada, Y ; Hashimoto, T ; Kuroyanagi, Y ; Kagawa, S ; Kubo, K ; Matsui, H
Oxford, UK; Malden, USA : Blackwell Science Inc
Published 2004Staff ViewISSN: 1524-475XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Aim: This study was aimed to confirm the usefulness of allogeneic cultured dermal substitute (CDS) in the treatment of skin defects after excision of skin cancer. Methods: Eleven elderly patients (mean age of 76.3 year old) with skin cancer were included in this study. Most of the patients had basic disease such as diabetes or ASO. Allogeneic CDS used in the study were produced at Kitasato University. The CDS were applied to skin defects with exposing bone or tendon after oncological surgery, and changed once or twice a week until the open wound became suitable for autologous skin grafting or healed completely. Results: Healthy granulation tissue was formed to cover the exposed bone or tendon in all cases. Only in one case, the treatment with allogeneic CDS was abandoned owing to undesirable infection. In eight cases, appropriate wound beds acceptable for autologous skin graft were prepared. In other two cases, the skin defect became smaller and eventually closed without skin graft. In ten cases with or without skin graft, undesirable scar contracture was not observed over prolonged follow-up. Conclusions: Elderly patients with skin cancer provide reconstructive surgeons with challenging problems when bone or bare tendon is exposed after oncological surgery. Flap transfer might be complicated especially when the patients suffered from a basic disease such as diabetes or ASO. This study has confirmed that the use of allogeneic CDS is a safe and reliable method to achieve wound healing in those high-risk patients.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesHashimoto, T. ; Yasumoto, S. ; Nagata, Y. ; Okamoto, T. ; Fujita, S.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary Two cases of IgA pemphigus, one of the subcorneal pustular dermatosis (SPD) type and one of the intraepidermal neutrophilic IgA dermatosis (IEN) type, are described. IgA anti-keratinocyte cell surface antibodies reacted only with the uppermost epidermis in the SPD type but with the entire epidermis in the IEN type. A cDNA transfection test for desmocollins (Dsc) revealed that IgA antibodies of the SPD type reacted with Dsc1, but the IEN type did not react with any of the Dsc isoforms (Dsc1–3). ELISA for desmoglein 1 (Dsg1) and Dsg3 showed that neither of the cases had antibodies to Dsg − of either the IgG or IgA subtype. These results confirm that the autoantigen in SPD-type IgA pemphigus is Dsc1, whereas the antigen in most cases of IEN-type IgA pemphigus is unknown.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesMorris, S. D. ; Mallipeddi, R. ; Oyama, N. ; Gratian, M. J. ; Harman, K. E. ; Bhogal, B. S. ; Black, M. M. ; Eady, R. A. J. ; Hashimoto, T. ; McGrath, J. A.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2230Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary We report a 51-year-old man with a 20-year history of chronic plaque psoriasis who developed an autoimmune subepidermal blistering eruption that had clinical features of bullous pemphigoid, erythema multiforme and epidermolysis bullosa acquisita. Investigations revealed a 1 : 400 titre circulating and in vivo bound IgG autoantibody that mapped to the dermal side of 1 m NaCl-split skin and localized to the lower lamina lucida/upper lamina densa on immunogold electron microscopy. Immunoblotting, using dermal extracts, showed serum binding to antigens of ≈ 200- and ≈ 260 kDa. Indirect immunofluorescence microscopy, using the patient's serum on archival skin sections taken from selected individuals with different forms of inherited epidermolysis bullosa as substrate, showed normal basement membrane labelling on all samples apart from recessive dystrophic epidermolysis bullosa skin (with inherent mutations in the type VII collagen gene): in these cases there was a complete absence of immunostaining. Clinically, the patient responded rapidly to combination treatment with intravenous immunoglobulin and oral corticosteroids, dapsone and mycophenolate mofetil. Autoimmune subepidermal blistering has been reported in other patients with psoriasis, although no specific target antigen has ever been determined. Our study provides preliminary evidence that, for this patient at least, the autoantibody may be targeted against a skin component closely associated with type VII collagen (the epidermolysis bullosa acquisita antigen). Therefore, we propose the term ‘psoriasis bullosa acquisita’ for this and possibly other patients with similar skin eruptions.Type of Medium: Electronic ResourceURL: