Search Results - (Author, Cooperation:T. C. Chao)

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  1. 1
    Staff View
    Publication Date:
    2012-12-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Catalytic Domain ; Cathepsin B/antagonists & inhibitors/*chemistry ; Crystallization ; Crystallography, X-Ray ; Enzyme Precursors/chemistry ; Glycosylation ; Models, Molecular ; Molecular Sequence Data ; Protein Conformation ; Protozoan Proteins/antagonists & inhibitors/*chemistry ; Sf9 Cells ; Spodoptera ; Trypanosoma brucei brucei/*enzymology ; X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    C. Kupitz ; S. Basu ; I. Grotjohann ; R. Fromme ; N. A. Zatsepin ; K. N. Rendek ; M. S. Hunter ; R. L. Shoeman ; T. A. White ; D. Wang ; D. James ; J. H. Yang ; D. E. Cobb ; B. Reeder ; R. G. Sierra ; H. Liu ; A. Barty ; A. L. Aquila ; D. Deponte ; R. A. Kirian ; S. Bari ; J. J. Bergkamp ; K. R. Beyerlein ; M. J. Bogan ; C. Caleman ; T. C. Chao ; C. E. Conrad ; K. M. Davis ; H. Fleckenstein ; L. Galli ; S. P. Hau-Riege ; S. Kassemeyer ; H. Laksmono ; M. Liang ; L. Lomb ; S. Marchesini ; A. V. Martin ; M. Messerschmidt ; D. Milathianaki ; K. Nass ; A. Ros ; S. Roy-Chowdhury ; K. Schmidt ; M. Seibert ; J. Steinbrener ; F. Stellato ; L. Yan ; C. Yoon ; T. A. Moore ; A. L. Moore ; Y. Pushkar ; G. J. Williams ; S. Boutet ; R. B. Doak ; U. Weierstall ; M. Frank ; H. N. Chapman ; J. C. Spence ; P. Fromme
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-07-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Crystallography, X-Ray ; Cyanobacteria/*chemistry ; *Models, Molecular ; Photosystem II Protein Complex/*chemistry ; Protein Structure, Tertiary
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    ISSN:
    1569-8041
    Keywords:
    follicular thyroid cancer ; papillary thyroid cancer ; polyclonal antibodies ; thyrotropin
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Active iodide uptake across the basal membrane mediated by human sodiumiodide symporter (hNIS) has been shown to be a process coupled with the flowof sodium. There is still controversy as to the amount of hNIS expressionpresent in different kinds of human thyroid cancer tissues. In this study, wepresent a 58-year-old women with follicular thyroid carcinoma with vertebraand skull metastases. 201Tl and 5 mCi 131I scans clearlydemonstrated the metastatic lesions in the brain of this patient. Thyroid andmetastatic tissues were then obtained for this study, which is aimed atcomparing the iodide trapping ability in vivo and in vitro of hNIS, and then comparing their expression in both thyroid tissue andmetastatic tissues. Polyclonal antibodies to hNIS and competitive RT–PCRwere used to analyze the symporter protein and mRNA expressed in follicularhuman thyroid and metastatic tissues. Positive staining of the symporterprotein was performed in the follicular thyroid carcinomas, otherwise, themetastatic tissues could not have demonstrated the protein in the staining.Follicular thyroid carcinoma tissues from thyroid were revealed around 5 pghNIS expressed in follicular thyroid carcinoma tissues from the thyroid.Otherwise, there was almost an absence of hNIS expression in the metastatictissue. These discrepancies of the expression in hNIS in vivo and in vitrostudies need further investigation.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses