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1Latest Papers from Table of Contents or Articles in PressB. P. Hubbard ; A. P. Gomes ; H. Dai ; J. Li ; A. W. Case ; T. Considine ; T. V. Riera ; J. E. Lee ; S. Y. E ; D. W. Lamming ; B. L. Pentelute ; E. R. Schuman ; L. A. Stevens ; A. J. Ling ; S. M. Armour ; S. Michan ; H. Zhao ; Y. Jiang ; S. M. Sweitzer ; C. A. Blum ; J. S. Disch ; P. Y. Ng ; K. T. Howitz ; A. P. Rolo ; Y. Hamuro ; J. Moss ; R. B. Perni ; J. L. Ellis ; G. P. Vlasuk ; D. A. Sinclair
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-03-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation ; Amino Acid Motifs ; Amino Acid Sequence ; Amino Acid Substitution ; Animals ; Cells, Cultured ; Enzyme Activation ; Forkhead Transcription Factors/chemistry/genetics ; Glutamic Acid/chemistry/genetics ; Heterocyclic Compounds with 4 or More Rings/chemistry/pharmacology ; Humans ; Hydrophobic and Hydrophilic Interactions ; Mice ; Molecular Sequence Data ; Myoblasts/drug effects/enzymology ; Protein Structure, Tertiary ; Sirtuin 1/*chemistry/genetics/*metabolism ; Stilbenes/chemistry/*pharmacology ; Substrate SpecificityPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1572-8145Keywords: Assembly planning ; knowledge-based Petri net ; expert system ; flexible assemblySource: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Automatic assembly planning is recognized as an important tool for reducing manufacturing costs in concurrent product and process development. A novel knowledge-based Petri net (KBPN) is defined, based on the incorporation of expert systems into the usual Petri nets, and used for a unified assembly knowledge representation scheme. A KBPN-approach integrated with a sequence generation algorithm is proposed for the modeling, planning, simulation, analysis and evaluation of the flexible assembly system (FAS). The developed KBPN-based assembly planning system (KAPS) can automatically adjust the deviations between the theoretical planning parameters and the process parameters of real assembly operations to guarantee the best strategies and plans (sequences) for flexible assembly. The research findings are exemplified with a simple assembly to show the effectiveness of the method.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1433-3015Keywords: Key words. Agent-based approach and system; Assembly design; Assembly planning; Concurrent design; Distributed expert systemSource: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: This paper addresses the development of an expert system for concurrent product design and assembly planning (CDAPFAES) including conceptual design, detailed design, assemblability analysis and design for assembly, assembly system design, assembly process planning and stimulation, and technical–economics justification. This approach is implemented through an agent-based framework with concurrent integration of multiple cooperative knowledge sources and software. This intelligent system can offer systematic assistance for assembly design and planning in the early stage of product development and facilitate, as far as possible, the use of flexible assembly equipment, including robots. Finally, this new design methodology is illustrated with a successful implementation of a switch product design.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1433-3015Keywords: Artificial intelligence ; Assembly planning ; Design for assembly ; Integrated product design ; Intelligent CAD/CAMSource: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract This paper reviews the relevant literature of the development of methodologies and systems for integrated intelligent design of assembled products and processes. Based on a combination of the concurrent engineering approach and artificial intelligence techniques, an assembly oriented intelligent scheme for the integration of design and planning is proposed, in which the following components or activities are considered and carried out concurrently and intelligently: assembly modelling and design (conceptual design; preliminary design; detailed design), assembly process planning, assembly system layout and design, assembly simulation, econo-technical (e.g. assembl-ability, assembly time and cost) and ergonomic analysis and evaluation. The literature is reviewed and discussed in relation to the methodologies and systems of implementing the above components or activities and an integrated environment to support them. In addition, some research of our group on this topic is introduced.Type of Medium: Electronic ResourceURL: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-02-03Publisher: Institute of Physics (IOP)Print ISSN: 1757-8981Electronic ISSN: 1757-899XTopics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPublished by: