Search Results - (Author, Cooperation:S. Sengupta)
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1T. J. Pugh ; S. D. Weeraratne ; T. C. Archer ; D. A. Pomeranz Krummel ; D. Auclair ; J. Bochicchio ; M. O. Carneiro ; S. L. Carter ; K. Cibulskis ; R. L. Erlich ; H. Greulich ; M. S. Lawrence ; N. J. Lennon ; A. McKenna ; J. Meldrim ; A. H. Ramos ; M. G. Ross ; C. Russ ; E. Shefler ; A. Sivachenko ; B. Sogoloff ; P. Stojanov ; P. Tamayo ; J. P. Mesirov ; V. Amani ; N. Teider ; S. Sengupta ; J. P. Francois ; P. A. Northcott ; M. D. Taylor ; F. Yu ; G. R. Crabtree ; A. G. Kautzman ; S. B. Gabriel ; G. Getz ; N. Jager ; D. T. Jones ; P. Lichter ; S. M. Pfister ; T. M. Roberts ; M. Meyerson ; S. L. Pomeroy ; Y. J. Cho
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-07-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cerebellar Neoplasms/classification/*genetics ; Child ; DEAD-box RNA Helicases/chemistry/genetics/metabolism ; DNA Helicases/chemistry/genetics ; DNA-Binding Proteins/genetics ; Exome/*genetics ; Genome, Human/*genetics ; Hedgehog Proteins/metabolism ; Histone-Lysine N-Methyltransferase/genetics/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; LIM Domain Proteins/genetics ; Medulloblastoma/classification/*genetics ; Models, Molecular ; Mutation/*genetics ; Neoplasm Proteins/genetics ; Nuclear Proteins/chemistry/genetics ; Promoter Regions, Genetic/genetics ; Protein Structure, Tertiary/genetics ; Proto-Oncogene Proteins/genetics ; Receptors, Cell Surface/genetics ; Repressor Proteins/genetics ; Signal Transduction ; TCF Transcription Factors/metabolism ; Transcription Factors/chemistry/genetics ; Tumor Suppressor Protein p53/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics/metabolismPublished by: -
2Staff View
Publication Date: 2018-12-13Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
3O. H. Yilmaz ; P. Katajisto ; D. W. Lamming ; Y. Gultekin ; K. E. Bauer-Rowe ; S. Sengupta ; K. Birsoy ; A. Dursun ; V. O. Yilmaz ; M. Selig ; G. P. Nielsen ; M. Mino-Kenudson ; L. R. Zukerberg ; A. K. Bhan ; V. Deshpande ; D. M. Sabatini
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: ADP-ribosyl Cyclase/metabolism ; Animals ; Antigens, CD/metabolism ; Caloric Restriction ; Cell Count ; Cell Division/drug effects ; Cyclic ADP-Ribose/metabolism ; Energy Intake/*physiology ; Female ; GPI-Linked Proteins/agonists/metabolism ; Intestines/*cytology ; Longevity/physiology ; Male ; Mice ; Multiprotein Complexes ; Paneth Cells/*cytology/drug effects/*metabolism ; Paracrine Communication ; Proteins/antagonists & inhibitors/*metabolism ; Regeneration/drug effects ; Signal Transduction ; Sirolimus/pharmacology ; Stem Cell Niche/drug effects/*physiology ; Stem Cells/*cytology/drug effects/*metabolism ; TOR Serine-Threonine KinasesPublished by: -
4Staff View
ISSN: 0167-4838Keywords: (Mushroom) ; Enzyme purification ; β-GlucosidaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
5Maximov, P. Y., Abderrahman, B., Fanning, S. W., Sengupta, S., Fan, P., Curpan, R. F., Rincon, D. M. Q., Greenland, J. A., Rajan, S. S., Greene, G. L., Jordan, V. C.
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
Published 2018Staff ViewPublication Date: 2018-06-27Publisher: The American Society for Pharmacology and Experimental Therapeutics (ASPET)Print ISSN: 0026-895XElectronic ISSN: 1521-0111Topics: Chemistry and PharmacologyMedicinePublished by: -
6Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for GlioblastomaNandhu, M. S., Behera, P., Bhaskaran, V., Longo, S. L., Barrera-Arenas, L. M., Sengupta, S., Rodriguez-Gil, D. J., Chiocca, E. A., Viapiano, M. S.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-02-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
7Kuo, C. S. ; Wakim, F. G. ; Sengupta, S. K. ; Tripathy, S. K.
[S.l.] : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Schottky barrier diodes have been fabricated using poly(3-hexylthiophene)(P3HT) as the semiconductor and indium as the metal. P3HT was doped with FeCl3 at room temperature to form a p-type semiconductor. The Schottky junctions of In on FeCl3-doped P3HT using pressure contact exhibit rectification ratios ranging from 104:1 to 106:1 at a bias of ±1 V.Type of Medium: Electronic ResourceURL: -
8Sengupta, S. ; Shi, Donglu ; Salem-Sugui, S. ; Wang, Zuning ; McGinn, P. J. ; DeMoranville, K.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We have conducted magnetic relaxation experiments to calculate the effective activation energy, U, as a function of critical current density. We have shown that, from the nonlinearity of U, one can explain the nonlogarithmic decay of magnetization in type II superconductors. The nonlinearity of U was considered by expanding U about a current density, J0. The coefficients of expansion were determined experimentally and were used to develop the relationship between U and J for both conventional type II superconductors (Nb3Sn filamentary) and high-Tc superconductors (YBa2Cu3O7−δ and Bi2Sr2CaCu2Oy single crystals). Both types of superconductor were observed to behave in similar fashion. We have also calculated U0 using the standard formulas and the intercepts of the tangent of the U vs M curve and have found the results to be comparable.Type of Medium: Electronic ResourceURL: -
9Marx, D. ; Sengupta, S. ; Nielaba, P.
College Park, Md. : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The rotational motion of homonuclear diatomic molecules confined to two dimensions at finite temperatures is discussed within the framework of path-integral Monte Carlo (PIMC) techniques. For single rotators the symmetry restriction on the total wave function coupling nuclear spin and rotations of these diatomic molecules is carried over to PIMC for fermionic and bosonic diatomic molecules. Three experimentally relevant quantum statistical averages are formulated, and quantum effects due to discrete level spacing and exchange are separated with the help of these averages. The method is applied to single N2 and H2 rotators adsorbed on graphite in the frozen-in crystal field which is due to the commensurate ((square root of)3×(square root of)3)R30° "2-in'' herringbone phase. Contrary to H2, exchange effects are negligible for N2 in the relevant temperature range. The resulting sign problem for certain combinations of molecule and averaging procedure is discussed. PIMC simulations of the phase transition from the translationally (square root of)3-ordered and orientationally disordered phase to the herringbone phase were carried out for complete N2 monolayers without a symmetry restriction on the wave function. Due to dispersive quantum fluctuations, transition temperature and ground-state order parameter are depressed by roughly 10% as compared to classical MC simulations of the same realistic model. In addition, the PIMC results are compared to quasiharmonic and quasiclassical approximations. The quasiharmonic treatment yields the correct order parameter suppression, the quasiclassical simulation the lowering of the transition temperature, but only the full quantum PIMC simulations describe the entire temperature range of interest correctly.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1365-2478Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: GeosciencesPhysicsNotes: A new spectral factorization method is presented for the estimation of a causal as well as a causally invertible ARMA operator from the correlation sequence of seismic traces. The method has been implemented for multichannel deconvolution of seismic traces with the aim of exploiting the trace-to-trace correlation that exists within seismograms. A layered earth model with a small reflectivity sequence has been considered, and the seismic traces have been considered as the output of a linear system driven by white noise reflection coefficient sequences. The present method is the concatenation of three algorithms, namely Kung's method for state variable (F,G,H) realization using a singular value decomposition (SVD) algorithm, Faurre's technique for computation of the strong spectral factor and Leverrier's algorithm for ARMA representation of the spectral factor. The inverted ARMA operator is used as a recursive filter for deconvolution of seismic traces. In the example shown, two traces with a covariance sequence of 160 ms length have been considered for multichannel deconvolution of stacked seismic traces. The results presented, when compared with those obtained from a conventional deconvolution algorithm, have shown encouraging prospects.Type of Medium: Electronic ResourceURL: -
11Pal, D. K. ; Das, T. ; Chaudhury, G. ; Sengupta, S.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2214Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Background Child behavioural problems in epilepsy originate from a poorly understood interplay between intrinsic, family and social factors.Methods We re-analysed data from a randomized controlled trial of antiepileptic treatment in rural India, using regression analysis to find risk factors for behavioural problems.Results Parental satisfaction with social support was positively and independently correlated with child behavioural problems (P = 0.03).Conclusion Our findings suggest parents’ interactions within their informal social support network, contrary to expectation, may increase risk for behavioural problems in their children. We suggest a possible explanation for this correlation as well as follow-up studies to investigate the social support-as-risk factor hypothesis.Type of Medium: Electronic ResourceURL: -
12Pal, D. K. ; Das, T ; Chaudhury, G. ; Sengupta, S. ; McConachie, H.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2214Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: -
13Pal, D. K. ; Chaudhury, G. ; Das, T. ; Sengupta, S.
Oxford, UK : Blackwell Science Ltd.
Published 2002Staff ViewISSN: 1365-2214Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Background Negative societal attitudes towards disability affect the adjustment of parents when their child is diagnosed with epilepsy. Recent studies have suggested that parental and child outcomes, including adjustment, can be influenced by non-directed social support to mothers of children with disability. The objective of our study was to test the hypothesis that maternal satisfaction with social support, measured at the beginning of treatment, would predict parental adjustment to the child’s epilepsy after 1 year of treatment.Methods We enrolled 46 mothers of children aged 6–18 years with epilepsy in the study. We measured social support using the modified Dunst family support scale, and parental adjustment using a locally validated instrument (S-PAM). Correlation was tested using a multiple linear regression model, allowing for confounding variables.Results Parental adjustment at outcome was positively independently correlated with satisfaction with social support at baseline, and negatively with severity of the child’s epilepsy. The regression model explained 34% of the total variance.Conclusions Taken together with evidence from previous studies, this finding supports the idea that helping parents to find more satisfaction within their (new or existing) social networks will promote adjustment to their child’s disability.Type of Medium: Electronic ResourceURL: -
14Sengupta, S. S. ; Roberts, D. ; Li, J.-F. ; Kim, M. C. ; Payne, D. A.
[S.l.] : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Tin-modified lead zirconate titanate thin layers were prepared by a sol-gel method. A room- temperature antiferroelectric (AFE) phase composition Pb0.99Nb0.02[(Zr0.58Sn0.42)0.96Ti0.04] 0.98O3 was prepared and examined for weak- and high-field dielectric properties as a function of temperature, with emphasis on field-induced AFE-ferroelectric (FE) switching characteristics. Thin layers processed with a lead oxide cover coat were found to be free of any secondary phases and showed improved properties. Room-temperature values of dielectric constant K'=390 and saturation polarization Ps=20 μC/cm2 were obtained with field-induced strains up to 0.15% in submicron grain structures. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Based on previously developed melt processing methods, Y2BaCuO5 (211) precipitates with various size were obtained in YBa2Cu3Ox (123). In particular, a wide distribution of 211 size from 100 Å to 10 μm has been found to exist in the matrix of 123, and strongly effected the critical current density, Jc. An enhancement of Jc was always found to be associated with the presence of extremely fine 211 precipitates. The flux pinning by these precipitates can be understood by considering the interaction of flux lines with cavities. It was found that although the flux lines are strongly pinned by cavities, the effectiveness decreases with the increasing number of flux lines trapped by them. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
16Sengupta, S. S. ; Park, S. M. ; Payne, D. A. ; Allen, L. H.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Stress development in thin layers of lead titanate prepared by sol-gel processing was monitored by in situ laser reflectance measurements. Layers were spin coated onto silicon substrates and thermally cycled to 500 °C. The shrinkage normal to the rigid substrate was determined by in situ ellipsometry. Changes that occurred on drying and firing, which related to densification and stress development, are reported. The observed changes were explained in terms of evaporation and solvent/polymeric network interactions at lower temperatures, and thermal expansion mismatch between the substrate and the coating after formation of the dense oxide. Crystallization into the perovskite structure occurred only in thicker or multideposited coatings, altering the state of stress from tensile, to progressively more compressive, on cooling. The importance of the choice of substrate material, deposition method and heat treatment conditions, in relation to stress development and dependent electrical properties, are discussed. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
17Middya, T. R. ; Basu, A. N. ; Sengupta, S.
[S.l.] : American Institute of Physics (AIP)
Published 1985Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A self-consistent solution for the effective elastic properties of polycrystalline and perfectly disordered multiphase composites has been discussed by using the T-matrix method under certain suitable approximations. Compared to the existing formulas these new relations for the disordered composites are very useful in practical situations for a quick and more accurate estimate of the effective elastic properties, in particular for a case where the composite has components with widely different values of the elastic constants. For comparison we have discussed the results based on Kröner's theory which also purports to solve the same problem. It is found that the two solutions do not agree. To resolve the difference we take help of Hill's exact solution of the composite problem when the components have equal rigidities. It is found that while Kröner's theory is inconsistent with the exact result the present self-consistent solution analytically reproduces it. Another interesting finding of the present investigation is that the approximations made in obtaining the self-consistent solution are exact in the limit of composites with equal-shear moduli. Finally it is indicated that although the results for composites have been derived for isotropic and cubic components it can be easily adapted for a composite with noncubic components.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: A method is described whereby a beam of positive hydrogen ions incident at grazing angles on an array of cesium-covered tungsten foils is used to produce H0 and H− particles by negative surface ionization. The results of these experiments indicate that the method can provide diagnostic beams of particles to hot plasmas and can also energy-analyze charge exchange neutrals emerging from hot plasmas.Type of Medium: Electronic ResourceURL: -
19Mathews, D. D. ; Patel, I. R. ; Sengupta, S. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1971Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: During 1969 and 1970 toxaemic patients attending the antenatal clinic at Sheppey General Hospital were admitted only if one or more of the following criteria were satisfied:1. The urine contained albumin on testing with Albustix.2. Urinary oestriol excretion was unsatisfactory.3. The obstetric condition and duration of gestation were such that either labour was to be induced or the baby delivered by elective Caesarean section.No case of eclampsia was seen. A maternal death followed a Caesarean section for accidental haemorrhage. The perinatal death rate in toxaemic patients fell from 4·8 to 3·1 per cent. The hospital bed days utilized by toxaemic patients were reduced by 72 per cent. Tt was concluded that testing of the urine for albumin by the patient herself might replace early admission in the prevention of eclampsia and that neither admission nor placental function testing were necessary for the protection of the baby in non-albuminuric toxaemia unless there was evidence of impaired fetal growth.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1467-999XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: EconomicsType of Medium: Electronic ResourceURL: