Search Results - (Author, Cooperation:S. Seal)
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1E. Ruark ; K. Snape ; P. Humburg ; C. Loveday ; I. Bajrami ; R. Brough ; D. N. Rodrigues ; A. Renwick ; S. Seal ; E. Ramsay ; V. Duarte Sdel ; M. A. Rivas ; M. Warren-Perry ; A. Zachariou ; A. Campion-Flora ; S. Hanks ; A. Murray ; N. Ansari Pour ; J. Douglas ; L. Gregory ; A. Rimmer ; N. M. Walker ; T. P. Yang ; J. W. Adlard ; J. Barwell ; J. Berg ; A. F. Brady ; C. Brewer ; G. Brice ; C. Chapman ; J. Cook ; R. Davidson ; A. Donaldson ; F. Douglas ; D. Eccles ; D. G. Evans ; L. Greenhalgh ; A. Henderson ; L. Izatt ; A. Kumar ; F. Lalloo ; Z. Miedzybrodzka ; P. J. Morrison ; J. Paterson ; M. Porteous ; M. T. Rogers ; S. Shanley ; L. Walker ; M. Gore ; R. Houlston ; M. A. Brown ; M. J. Caufield ; P. Deloukas ; M. I. McCarthy ; J. A. Todd ; C. Turnbull ; J. S. Reis-Filho ; A. Ashworth ; A. C. Antoniou ; C. J. Lord ; P. Donnelly ; N. Rahman
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Breast Neoplasms/*genetics ; Cluster Analysis ; Exons ; Female ; Genetic Predisposition to Disease/*genetics ; Humans ; Isoenzymes/genetics ; Lymphocytes/metabolism ; *Mosaicism ; *Mutation ; Ovarian Neoplasms/*genetics ; Phosphoprotein Phosphatases/*genetics ; Sequence Analysis, DNA ; Tumor Suppressor Protein p53/metabolismPublished by: -
2Warwick, T. ; Franck, K. ; Kortright, J. B. ; Meigs, G. ; Moronne, M. ; Myneni, S. ; Rotenberg, E. ; Seal, S. ; Steele, W. F.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: Design and performance of a scanning transmission x-ray microscope (STXM) at the Advanced Light Source is described. This instrument makes use of a high brightness undulator beamline and extends the STXM technique to new areas of research. After 2.5 years of development it is now an operational tool for research in polymer science, environmental chemistry, and magnetic materials. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
3Gibson, R. W. ; Mpembe, I. ; Alicai, T. ; Carey, E. E. ; Mwanga, R. O. M. ; Seal, S. E. ; Vetten, H. J.
Oxford, U.K. and Cambridge, USA : Blackwell Publishers
Published 1998Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Sweet potato virus disease (SPVD) is the name used to describe a range of severe symptoms in different cultivars of sweet potato, comprising overall plant stunting combined with leaf narrowing and distortion, and chlorosis, mosaic or vein-clearing. Affected plants of various cultivars were collected from several regions of Uganda. All samples contained the aphid-borne sweet potato feathery mottle potyvirus (SPFMV) and almost all contained the whitefly-borne sweet potato chlorotic stunt closterovirus (SPCSV). SPCSV was detected by a mix of monoclonal antibodies (MAb) previously shown to react only to a Kenyan isolate of SPCSV, but not by a mixture of MAb that detected SPCSV isolates from Nigeria and other countries. Sweet potato chlorotic fleck virus (SPCFV) and sweet potato mild mottle ipomovirus (SPMMV) were seldom detected in SPVD-affected plants, while sweet potato latent virus (SPLV) was never detected. Isolates of SPFMV and SPCSV obtained by insect transmissions together induced typical symptoms of SPVD when graft-inoculated to virus-free sweet potato. SPCSV alone caused stunting and either purpling or yellowing of middle and lower leaves when graft-inoculated to virus-free plants of two cultivars. Similarly diseased naturally inoculated field plants were shown consistently to contain SPCSV. Both this disease and SPVD spread rapidly in a sweet potato crop.Type of Medium: Electronic ResourceURL: -
4Black, R. ; Seal, S. ; Abubakar, Zakia ; Nono-Womdim, R. ; Swai, I.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: -
5Monger, W. A. ; Seal, S. ; Cotton, S. ; Foster, G. D.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: An RT-PCR based detection method for Cassava brown streak virus (CBSV)-infected cassava has been developed. The RT-PCR detection method described includes RNA extraction methods for cassava leaves, a distinct primer set for the virus and RT-PCR conditions. The primers were designed to the virus coat protein gene and generate a virus-specific product of 231 bp from infected cassava. The test can detect the virus in the new growth of cassava sticks before any disease symptoms are visible. This test was used successfully with infected cassava from both Tanzania and Mozambique. Three isolates from Tanzania were found to exhibit different symptoms on the secondary host plants Nicotiana benthamiana and N. tabacum SR1. They have nucleotide sequence variation within the coat protein region of up to 8% and amino acid differences of up to 6%.Type of Medium: Electronic ResourceURL: -
6Chowda Reddy, R. V. ; Muniyappa, V. ; Colvin, J. ; Seal, S.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: -
7Monger, W. A. ; Seal, S. ; Isaac, A. M. ; Foster, G. D.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: A partial sequence of 1114 nucleotides of a virus from cassava brown streak diseased (CBSD) material was obtained. Alignment of the predicted amino acid sequence with those of other members of the Potyviridae showed closest identity with the coat protein of Sweet potato mild mottle virus (genus Ipomovirus). The predicted amino acid sequence has one open reading frame with a 3′ untranslated region of 144 nucleotides and a poly(A) tail. The expressed protein was shown to cross-react with an antiserum raised previously to a virus isolated from CBSD material. Evidence presented suggests that CBSD is caused by Cassava brown streak virus, a tentative member of the genus Ipomovirus, as this virus is consistently found associated with CBSD.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0040-6090Keywords: Aluminum oxide ; Binding energy ; Charging ; OxidesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
9WEEKS, D. P. ; VERMA, D. P. S. ; SEAL, S. N. ; MARCUS, A.
[s.l.] : Nature Publishing Group
Published 1972Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Table 1 TMV-RNA Directed 14C-Amino-acid Incorporation by Isolated Wheat Embryo Ribosomal Subunits 14C-Amino-acid incorporation (pmol) 40S 0.17 60S 0.27 40S + 60S 7.63 40S + 60S (-TMV-RNA) 0.36 Incubation of 0.4 ml. final volume contained: 25 mM Tris-acetate, pH 8.1, 1.0 mM ATP, 8 mM creatine ...Type of Medium: Electronic ResourceURL: -
10Takahashi, M. ; Rapley, E. ; Biggs, P.J. ; Lakhani, S.R ; Cooke, D. ; Hansen, J. ; Blair, E. ; Hofmann, B. ; Siebert, R. ; Turner, G. ; Evans, D.G. ; Schrander-Stumpel, C. ; Beemer, F.A. ; van Vloten, W.A. ; Breuning, M.H. ; van den Ouweland, A. ; Halley, D. ; Delpech, B. ; Cleveland, M. ; Leigh, I. ; Chapman, P. ; Burn, J. ; Hohl, D. ; Görög, J.-P. ; Seal, S.
Springer
Published 2000Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. Familial cylindromatosis is an autosomal dominant predisposition to multiple neoplasms of the skin appendages. The susceptibility gene has previously been mapped to chromosome 16q12–q13 and has features of a recessive oncogene/tumour suppressor gene. We have now evaluated 19 families with this disease by a combination of genetic linkage analysis and loss of heterozygosity in cylindromas from affected individuals. All 15 informative families show linkage to this locus, providing no evidence for genetic heterogeneity. Recombinant mapping has placed the gene in an interval of approximately 1 Mb. There is no evidence, between families, of haplotype sharing that might be indicative of common founder mutations.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1573-4811Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1573-4889Keywords: austenitic stainless steels ; isothermal ; cyclic ; oxidation ; superficial CeO2 coatingSource: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract The influence of superficially applied CeO2 coatings on the isothermal-oxidation behavior, preceded by nonisothermal heating, as well as cyclic-oxidation behavior of three grades of austenitic stainless steel (AISI-316, −321, and −304), in dry air is reported. The superficial coating had a thickness of 2.1 μm. The linear heating rate employed was 6 K min−1 up to a maximum temperature of 1423 K, and the isothermal holding temperature was 1273 K. The results clearly depict that CeO2 coatings not only reduced the rates of scale growth for all three varieties of steel but also imparted improved scale adhesion to the respective alloy substrates, as evident from the fact that the coated steels could withstand a number of thermal cycles without scale rupture. In the bare condition, 321-grade steel exhibited the best performance. However, in the presence of the coating, the improved performances of 316 and 321 grades were almost identical, whereas the 304 variety showed improvement only in the first cycle of exposure. The kinetics results have been substantiated by postoxidation analyses of the alloy/scale combinations by SEM, EDS, EPMA, and XRD techniques to reveal the role of rare-earthoxide coatings on the observed behavior.Type of Medium: Electronic ResourceURL: -
13Badge, J. ; Brunt, A. ; Carson, R. ; Dagless, E. ; Karamagioli, M. ; Phillips, S. ; Seal, S. ; Turner, R. ; Foster, G. D.
Springer
Published 1996Staff ViewISSN: 1573-8469Keywords: carlavirus-specific primer ; CMMV ; nucleotide sequence ; PCRSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract Cowpea mild mottle virus (CMMV) has physicochemical properties typical of carlaviruses, but has remained unclassified due to a number of unusual properties, including no serological cross-reaction with 18 carlaviruses; production of brush-like inclusion bodiesin vivo; and the ability to be transmitted by whiteflies (Bermisia tabaci). In this paper we report the use of a carlavirus specific PCR primer to identify CMMV as a member of the carlavirus group. This is confirmed by nucleotide sequence (958 nucleotides) from the 3′ terminal region of CMMV RNA which contains a partial open reading frame (ORF) having high similarity with the coat proteins of other carlaviruses. The sequence also contains an 11.7K ORF at the 3′ terminus, containing a ‘zinc-finger’ motif which is unique to carlaviruses.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1573-4811Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract The chemical and physical interaction of liquid metal surfaces with various substrates is an important, largely unexplored aspect of technology, with implications in composite science and catalysis. In the present case, we have employed X-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES), in conjugation with sessile drop wettability tests, to examine the interfacial properties and surface chemistry of the systems formed by adding liquid drops of select Al–Ti alloys to graphite substrates. A variety of different chemical states was revealed in the XPS results, suggesting the formation of separate regions composed of elemental metals, alloys and carbides. Many of the specific features detected appear to depend on the various treatment properties, e.g. the temperature, bulk alloy composition, size and shape of the alloy drop and time of interaction. The surface analyses were also supported by optical microscopy, scanning electron microscopy (SEM) and X-ray diffraction (XRD) studies. The combined results suggest the induction of a strong reaction between titanium and carbon, resulting in an improvement in the wettability of the alloy with the graphite substrate and a corresponding structure transformation from the (LAl–Ti+Al3Ti) state to the (LAl–Ti+TiC) semi-liquid state. © 1998 Kluwer Academic PublishersType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1434-6079Keywords: 34.80.DpSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The multiple scattering approach of Das and Seal, which was applied earlier to calculate the triple differential cross section for the ionization of atomic hydrogen by electrons is now used to calculate the double and the single differential cross sections for the same system. The range of the incident electron energy is taken to be 100–250 eV. The present results are compared with the measured results of Shyn and with the available distorted wave Born approximation results.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1434-6079Keywords: 34.80.DpSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract A new theory, recently suggested by one of the authors, is tested here in case of ionization of hydrogen atoms by electrons at intermediate energies for large momentum transfers. The present results give good description of the available experimental data and in some respects are better than those of other theories.Type of Medium: Electronic ResourceURL: