Search Results - (Author, Cooperation:S. R. Harris)
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1N. J. Croucher ; S. R. Harris ; C. Fraser ; M. A. Quail ; J. Burton ; M. van der Linden ; L. McGee ; A. von Gottberg ; J. H. Song ; K. S. Ko ; B. Pichon ; S. Baker ; C. M. Parry ; L. M. Lambertsen ; D. Shahinas ; D. R. Pillai ; T. J. Mitchell ; G. Dougan ; A. Tomasz ; K. P. Klugman ; J. Parkhill ; W. P. Hanage ; S. D. Bentley
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-01-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological ; Anti-Bacterial Agents/pharmacology ; Antigenic Variation ; DNA Transposable Elements ; Drug Resistance, Multiple, Bacterial ; *Evolution, Molecular ; Genome, Bacterial ; Humans ; Molecular Epidemiology ; Phylogeny ; Phylogeography ; Pneumococcal Infections/drug therapy/*microbiology ; Pneumococcal Vaccines/immunology ; Polymorphism, Single Nucleotide ; Prophages/genetics ; *Recombination, Genetic ; Selection, Genetic ; Serotyping ; Streptococcus Phages/genetics ; Streptococcus pneumoniae/classification/drug effects/*genetics/immunologyPublished by: -
2A. Mutreja ; D. W. Kim ; N. R. Thomson ; T. R. Connor ; J. H. Lee ; S. Kariuki ; N. J. Croucher ; S. Y. Choi ; S. R. Harris ; M. Lebens ; S. K. Niyogi ; E. J. Kim ; T. Ramamurthy ; J. Chun ; J. L. Wood ; J. D. Clemens ; C. Czerkinsky ; G. B. Nair ; J. Holmgren ; J. Parkhill ; G. Dougan
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-08-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cholera/*epidemiology/microbiology/*transmission ; Genome, Bacterial/genetics ; Haiti/epidemiology ; Humans ; Likelihood Functions ; Molecular Epidemiology ; Pandemics/*statistics & numerical data ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Vibrio cholerae/classification/*genetics/*isolation & purification ; Zimbabwe/epidemiologyPublished by: -
3K. I. Bos ; K. M. Harkins ; A. Herbig ; M. Coscolla ; N. Weber ; I. Comas ; S. A. Forrest ; J. M. Bryant ; S. R. Harris ; V. J. Schuenemann ; T. J. Campbell ; K. Majander ; A. K. Wilbur ; R. A. Guichon ; D. L. Wolfe Steadman ; D. C. Cook ; S. Niemann ; M. A. Behr ; M. Zumarraga ; R. Bastida ; D. Huson ; K. Nieselt ; D. Young ; J. Parkhill ; J. E. Buikstra ; S. Gagneux ; A. C. Stone ; J. Krause
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bone and Bones/microbiology ; Europe/ethnology ; Genome, Bacterial/*genetics ; Genomics ; History, Ancient ; Human Migration/history ; Humans ; Mycobacterium tuberculosis/*genetics ; Peru ; Phylogeny ; Pinnipedia/*microbiology ; Tuberculosis/*history/*microbiology/transmission ; Zoonoses/*history/*microbiology/transmissionPublished by: -
4A. E. Mather ; S. W. Reid ; D. J. Maskell ; J. Parkhill ; M. C. Fookes ; S. R. Harris ; D. J. Brown ; J. E. Coia ; M. R. Mulvey ; M. W. Gilmour ; L. Petrovska ; E. de Pinna ; M. Kuroda ; M. Akiba ; H. Izumiya ; T. R. Connor ; M. A. Suchard ; P. Lemey ; D. J. Mellor ; D. T. Haydon ; N. R. Thomson
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-09-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Drug Resistance, Multiple, Bacterial/*genetics ; Epidemics ; Genome, Bacterial ; *Host-Pathogen Interactions ; Humans ; Molecular Sequence Data ; Phylogeny ; Salmonella Infections/epidemiology/*microbiology ; Salmonella Infections, Animal/epidemiology/*microbiology ; Salmonella typhimurium/*classification/drug effects/genetics ; Zoonoses/*microbiologyPublished by: -
5M. B. Burns ; L. Lackey ; M. A. Carpenter ; A. Rathore ; A. M. Land ; B. Leonard ; E. W. Refsland ; D. Kotandeniya ; N. Tretyakova ; J. B. Nikas ; D. Yee ; N. A. Temiz ; D. E. Donohue ; R. M. McDougle ; W. L. Brown ; E. K. Law ; R. S. Harris
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-02-08Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Biocatalysis ; Breast Neoplasms/*enzymology/*genetics/pathology ; Cell Death ; Cell Line, Tumor ; Cytidine Deaminase/genetics/*metabolism ; DNA Damage/genetics ; DNA Fragmentation ; DNA, Neoplasm/genetics/metabolism ; Deamination ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Humans ; *Mutagenesis/genetics ; Phenotype ; *Point Mutation/genetics ; Tumor Suppressor Protein p53/genetics/metabolism ; Up-Regulation ; Uracil/metabolismPublished by: -
6F. Yue ; Y. Cheng ; A. Breschi ; J. Vierstra ; W. Wu ; T. Ryba ; R. Sandstrom ; Z. Ma ; C. Davis ; B. D. Pope ; Y. Shen ; D. D. Pervouchine ; S. Djebali ; R. E. Thurman ; R. Kaul ; E. Rynes ; A. Kirilusha ; G. K. Marinov ; B. A. Williams ; D. Trout ; H. Amrhein ; K. Fisher-Aylor ; I. Antoshechkin ; G. DeSalvo ; L. H. See ; M. Fastuca ; J. Drenkow ; C. Zaleski ; A. Dobin ; P. Prieto ; J. Lagarde ; G. Bussotti ; A. Tanzer ; O. Denas ; K. Li ; M. A. Bender ; M. Zhang ; R. Byron ; M. T. Groudine ; D. McCleary ; L. Pham ; Z. Ye ; S. Kuan ; L. Edsall ; Y. C. Wu ; M. D. Rasmussen ; M. S. Bansal ; M. Kellis ; C. A. Keller ; C. S. Morrissey ; T. Mishra ; D. Jain ; N. Dogan ; R. S. Harris ; P. Cayting ; T. Kawli ; A. P. Boyle ; G. Euskirchen ; A. Kundaje ; S. Lin ; Y. Lin ; C. Jansen ; V. S. Malladi ; M. S. Cline ; D. T. Erickson ; V. M. Kirkup ; K. Learned ; C. A. Sloan ; K. R. Rosenbloom ; B. Lacerda de Sousa ; K. Beal ; M. Pignatelli ; P. Flicek ; J. Lian ; T. Kahveci ; D. Lee ; W. J. Kent ; M. Ramalho Santos ; J. Herrero ; C. Notredame ; A. Johnson ; S. Vong ; K. Lee ; D. Bates ; F. Neri ; M. Diegel ; T. Canfield ; P. J. Sabo ; M. S. Wilken ; T. A. Reh ; E. Giste ; A. Shafer ; T. Kutyavin ; E. Haugen ; D. Dunn ; A. P. Reynolds ; S. Neph ; R. Humbert ; R. S. Hansen ; M. De Bruijn ; L. Selleri ; A. Rudensky ; S. Josefowicz ; R. Samstein ; E. E. Eichler ; S. H. Orkin ; D. Levasseur ; T. Papayannopoulou ; K. H. Chang ; A. Skoultchi ; S. Gosh ; C. Disteche ; P. Treuting ; Y. Wang ; M. J. Weiss ; G. A. Blobel ; X. Cao ; S. Zhong ; T. Wang ; P. J. Good ; R. F. Lowdon ; L. B. Adams ; X. Q. Zhou ; M. J. Pazin ; E. A. Feingold ; B. Wold ; J. Taylor ; A. Mortazavi ; S. M. Weissman ; J. A. Stamatoyannopoulos ; M. P. Snyder ; R. Guigo ; T. R. Gingeras ; D. M. Gilbert ; R. C. Hardison ; M. A. Beer ; B. Ren
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-11-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Lineage/genetics ; Chromatin/genetics/metabolism ; Conserved Sequence/genetics ; DNA Replication/genetics ; Deoxyribonuclease I/metabolism ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genome/*genetics ; Genome-Wide Association Study ; *Genomics ; Humans ; Mice/*genetics ; *Molecular Sequence Annotation ; RNA/genetics ; Regulatory Sequences, Nucleic Acid/genetics ; Species Specificity ; Transcription Factors/metabolism ; Transcriptome/geneticsPublished by: -
7D. P. Locke ; L. W. Hillier ; W. C. Warren ; K. C. Worley ; L. V. Nazareth ; D. M. Muzny ; S. P. Yang ; Z. Wang ; A. T. Chinwalla ; P. Minx ; M. Mitreva ; L. Cook ; K. D. Delehaunty ; C. Fronick ; H. Schmidt ; L. A. Fulton ; R. S. Fulton ; J. O. Nelson ; V. Magrini ; C. Pohl ; T. A. Graves ; C. Markovic ; A. Cree ; H. H. Dinh ; J. Hume ; C. L. Kovar ; G. R. Fowler ; G. Lunter ; S. Meader ; A. Heger ; C. P. Ponting ; T. Marques-Bonet ; C. Alkan ; L. Chen ; Z. Cheng ; J. M. Kidd ; E. E. Eichler ; S. White ; S. Searle ; A. J. Vilella ; Y. Chen ; P. Flicek ; J. Ma ; B. Raney ; B. Suh ; R. Burhans ; J. Herrero ; D. Haussler ; R. Faria ; O. Fernando ; F. Darre ; D. Farre ; E. Gazave ; M. Oliva ; A. Navarro ; R. Roberto ; O. Capozzi ; N. Archidiacono ; G. Della Valle ; S. Purgato ; M. Rocchi ; M. K. Konkel ; J. A. Walker ; B. Ullmer ; M. A. Batzer ; A. F. Smit ; R. Hubley ; C. Casola ; D. R. Schrider ; M. W. Hahn ; V. Quesada ; X. S. Puente ; G. R. Ordonez ; C. Lopez-Otin ; T. Vinar ; B. Brejova ; A. Ratan ; R. S. Harris ; W. Miller ; C. Kosiol ; H. A. Lawson ; V. Taliwal ; A. L. Martins ; A. Siepel ; A. Roychoudhury ; X. Ma ; J. Degenhardt ; C. D. Bustamante ; R. N. Gutenkunst ; T. Mailund ; J. Y. Dutheil ; A. Hobolth ; M. H. Schierup ; O. A. Ryder ; Y. Yoshinaga ; P. J. de Jong ; G. M. Weinstock ; J. Rogers ; E. R. Mardis ; R. A. Gibbs ; R. K. Wilson
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-01-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Centromere/genetics ; Cerebrosides/metabolism ; Chromosomes ; Evolution, Molecular ; Female ; Gene Rearrangement/genetics ; Genetic Speciation ; *Genetic Variation ; Genetics, Population ; Genome/*genetics ; Humans ; Male ; Phylogeny ; Pongo abelii/*genetics ; Pongo pygmaeus/*genetics ; Population Density ; Population Dynamics ; Species SpecificityPublished by: -
8S. Jager ; D. Y. Kim ; J. F. Hultquist ; K. Shindo ; R. S. LaRue ; E. Kwon ; M. Li ; B. D. Anderson ; L. Yen ; D. Stanley ; C. Mahon ; J. Kane ; K. Franks-Skiba ; P. Cimermancic ; A. Burlingame ; A. Sali ; C. S. Craik ; R. S. Harris ; J. D. Gross ; N. J. Krogan
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-12-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Affinity Labels ; Animals ; Core Binding Factor beta Subunit/*metabolism ; Cullin Proteins/metabolism ; Cytidine Deaminase/*metabolism ; Gene Knockdown Techniques ; Gene Products, vif/*metabolism ; Genetic Complementation Test ; HEK293 Cells ; HIV Infections/*metabolism/*virology ; HIV-1/*physiology ; Host-Pathogen Interactions ; Humans ; Jurkat Cells ; Macaca mulatta/metabolism/virology ; Mass Spectrometry ; Models, Biological ; Protein Binding ; Proteolysis ; Simian Immunodeficiency Virus/metabolism ; Ubiquitin-Protein Ligases/chemistry/metabolism ; Ubiquitination ; Virus Replication ; vif Gene Products, Human Immunodeficiency Virus/*metabolismPublished by: -
9Mehta, R. S. ; Gunnett, C. A. ; Harris, S. R. ; Bunce, O. R. ; Hartle, D. K.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. The purpose of this study was to determine whether high ω-3 (19% menhaden oil, 1% corn oil) or high ω-6 (20% corn oil) fatty acid diets would decrease expression of hypertension in the female spontaneously hypertensive rat (SHR), promote tumourigenesis in the rat 7,12-dimethyl-benz[a]anthracene (DMBA) model of mammary cancer or increase the susceptibility of the mammary gland to lipid peroxidation. A group of rats on a 5% corn oil diet served as the low fat control group.2. We found that the high ω-3 and high ω-6 fatty acid diets did not significantly decrease mean arterial pressure. Marked differences occurred between the effects of ω-3 and ω-6 high fatty acid diets on baseline oxidation, auto-oxidation and iron-ascorbate catalyzed oxidation. The ω-3 diet showed 675% increase in basal oxidation, a 2624% increase in auto-oxidation and a 4244% increase in iron-ascorbate catalyzed oxidation compared to the ω-6 diet in mammary tissue homogenates. Although all rats were given 5 mg DMBA (i.g.), no mammary tumours were observed in any of the dietary groups.3. We conclude that: (i) high polyunsaturated fatty acid diets do not decrease blood pressure in the female SHR; (ii) high fish oil diet markedly increases oxidative potential in the mammary gland; and (iii) the female SHR is resistant to DMBA-induced tumourigenesis.Type of Medium: Electronic ResourceURL: