Search Results - (Author, Cooperation:S. Price)
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1David H. Case, Vijay K. Srirambhatla, Rui Guo, Rona E. Watson, Louise S. Price, Hector Polyzois, Jeremy K. Cockcroft, Alastair J. Florence, Derek A. Tocher, Sarah L. Price
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-08-16Publisher: American Chemical Society (ACS)Print ISSN: 1528-7483Electronic ISSN: 1528-7505Topics: Chemistry and PharmacologyGeosciencesPhysicsPublished by: -
2M. J. Garnett ; E. J. Edelman ; S. J. Heidorn ; C. D. Greenman ; A. Dastur ; K. W. Lau ; P. Greninger ; I. R. Thompson ; X. Luo ; J. Soares ; Q. Liu ; F. Iorio ; D. Surdez ; L. Chen ; R. J. Milano ; G. R. Bignell ; A. T. Tam ; H. Davies ; J. A. Stevenson ; S. Barthorpe ; S. R. Lutz ; F. Kogera ; K. Lawrence ; A. McLaren-Douglas ; X. Mitropoulos ; T. Mironenko ; H. Thi ; L. Richardson ; W. Zhou ; F. Jewitt ; T. Zhang ; P. O'Brien ; J. L. Boisvert ; S. Price ; W. Hur ; W. Yang ; X. Deng ; A. Butler ; H. G. Choi ; J. W. Chang ; J. Baselga ; I. Stamenkovic ; J. A. Engelman ; S. V. Sharma ; O. Delattre ; J. Saez-Rodriguez ; N. S. Gray ; J. Settleman ; P. A. Futreal ; D. A. Haber ; M. R. Stratton ; S. Ramaswamy ; U. McDermott ; C. H. Benes
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-31Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Line, Tumor ; Cell Survival/drug effects ; Drug Resistance, Neoplasm/drug effects/*genetics ; *Drug Screening Assays, Antitumor ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Neoplasm/*genetics ; Genetic Markers/*genetics ; Genome, Human/*genetics ; Genomics ; Humans ; Indoles/pharmacology ; Neoplasms/*drug therapy/*genetics/pathology ; Oncogene Proteins, Fusion/genetics ; Pharmacogenetics ; Phthalazines/pharmacology ; Piperazines/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors ; Proto-Oncogene Protein c-fli-1/genetics ; RNA-Binding Protein EWS/genetics ; Sarcoma, Ewing/drug therapy/genetics/pathologyPublished by: -
3G. Hatzivassiliou ; J. R. Haling ; H. Chen ; K. Song ; S. Price ; R. Heald ; J. F. Hewitt ; M. Zak ; A. Peck ; C. Orr ; M. Merchant ; K. P. Hoeflich ; J. Chan ; S. M. Luoh ; D. J. Anderson ; M. J. Ludlam ; C. Wiesmann ; M. Ultsch ; L. S. Friedman ; S. Malek ; M. Belvin
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation/drug effects ; Azetidines/pharmacology ; Cell Survival/drug effects ; Clinical Trials as Topic ; Crystallography, X-Ray ; Enzyme Activation/drug effects ; Feedback, Physiological/drug effects ; Genes, ras/*genetics ; HCT116 Cells ; Humans ; MAP Kinase Signaling System/drug effects ; Mitogen-Activated Protein Kinase Kinases/*antagonists & ; inhibitors/chemistry/metabolism ; Models, Molecular ; Neoplasms/*enzymology/*genetics/pathology ; Oncogene Protein p21(ras)/*genetics ; Phosphorylation/drug effects ; Phosphoserine/metabolism ; Piperidines/pharmacology ; Protein Kinase Inhibitors/*pharmacology ; Proto-Oncogene Proteins B-raf/genetics/*metabolismPublished by: -
4J. H. Williams ; A. DeBenedictis ; R. Ghanadan ; A. Mahone ; J. Moore ; W. R. Morrow, 3rd ; S. Price ; M. S. Torn
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-11-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
5H. S. Kuehn ; W. Ouyang ; B. Lo ; E. K. Deenick ; J. E. Niemela ; D. T. Avery ; J. N. Schickel ; D. Q. Tran ; J. Stoddard ; Y. Zhang ; D. M. Frucht ; B. Dumitriu ; P. Scheinberg ; L. R. Folio ; C. A. Frein ; S. Price ; C. Koh ; T. Heller ; C. M. Seroogy ; A. Huttenlocher ; V. K. Rao ; H. C. Su ; D. Kleiner ; L. D. Notarangelo ; Y. Rampertaap ; K. N. Olivier ; J. McElwee ; J. Hughes ; S. Pittaluga ; J. B. Oliveira ; E. Meffre ; T. A. Fleisher ; S. M. Holland ; M. J. Lenardo ; S. G. Tangye ; G. Uzel
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-09-13Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Animals ; B-Lymphocytes/immunology ; CTLA-4 Antigen/*genetics ; Female ; Forkhead Transcription Factors/immunology ; *Germ-Line Mutation ; *Haploinsufficiency ; Humans ; Immune System Diseases/*genetics ; Immunity/*genetics ; Male ; Mice ; Mice, Mutant Strains ; Pedigree ; T-Lymphocytes, Regulatory/immunology ; Young AdultPublished by: -
6B. Lo ; K. Zhang ; W. Lu ; L. Zheng ; Q. Zhang ; C. Kanellopoulou ; Y. Zhang ; Z. Liu ; J. M. Fritz ; R. Marsh ; A. Husami ; D. Kissell ; S. Nortman ; V. Chaturvedi ; H. Haines ; L. R. Young ; J. Mo ; A. H. Filipovich ; J. J. Bleesing ; P. Mustillo ; M. Stephens ; C. M. Rueda ; C. A. Chougnet ; K. Hoebe ; J. McElwee ; J. D. Hughes ; E. Karakoc-Aydiner ; H. F. Matthews ; S. Price ; H. C. Su ; V. K. Rao ; M. J. Lenardo ; M. B. Jordan
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-07-25Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Abatacept ; Adaptor Proteins, Signal Transducing/genetics/*metabolism ; Adolescent ; Autoimmune Diseases/*drug therapy/metabolism ; CTLA-4 Antigen/*deficiency/genetics ; Child ; Chloroquine/pharmacology ; Common Variable Immunodeficiency/*drug therapy/metabolism ; Endosomes/metabolism ; Female ; Forkhead Transcription Factors/analysis ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Immunoconjugates/*therapeutic use ; Lung Diseases, Interstitial/drug therapy/metabolism ; Lymphocyte Activation ; Lysosomes/metabolism ; Male ; Proteolysis ; T-Lymphocytes/drug effects/immunology ; Young AdultPublished by: -
7Staff View
ISSN: 1588-2861Source: Springer Online Journal Archives 1860-2000Topics: Information Science and LibrarianshipNature of Science, Research, Systems of Higher Education, Museum ScienceNotes: Abstract Following the methodology established byPrice, this paper analyzes the empirical evidence of citation matrices. Using the data cleaned and tabulated by Computer Horizons, Inc. from the Science Citation Index data banks, it is shown that the non-diagonal elements of the square citation matrices can be accounted for very satisfactorily by assigning each nation a characteristic output and input coefficient in each field measured; the ratio of these coefficients provides a measure of quality. Deviations from this simple model give measures of particular linkage strengths between nations showing some evidence of preferences and avoidances that exist for reason of language, social structure, etc. It is also shown that the diagonal data can be accounted for by the measurable phenomenon that each nation seems to publish partly for the international knowledge system and party for its own domestic purposes. Thus, three parameters and a cluster map can parsimoniously describe the citation data within the limits of random error.Type of Medium: Electronic ResourceURL: -
8Quispel-Janssen, J. M., Badhai, J., Schunselaar, L., Price, S., Brammeld, J., Iorio, F., Kolluri, K., Garnett, M., Berns, A., Baas, P., McDermott, U., Neefjes, J., Alifrangis, C.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-01-04Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
9M. Esposito, T. Price, S. Manger, C. Waltham, T. Anaxagoras, D. J. Parker, J. Nieto-Camero and N.M. Allinson
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-11-23Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
10Fournier, P. G. ; Eland, J. H. D. ; Millie, P. ; Svensson, S. ; Price, S. D. ; Fournier, J. ; Comtet, G. ; Wannberg, B. ; Karlsson, L. ; Baltzer, P. ; Kaddouri, A. ; Gelius, U.
College Park, Md. : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Six features observed in the energy distribution of H− ions arising from the single collision double charge transfer of 3–5 keV protons on nitrogen dioxide are interpreted as vertical double ionization energies of NO2 of 35.1, 38.1, 39.5, 41.0, 43.2, and 46.8 eV to form doublet states. Theoretical energies of the first 13 doublet and quartet electronic states of NO2+2 have been calculated by the ab initio CIPSI method at a fixed N–O distance and for several O–N–O bending angles. Thresholds and kinetic energy releases observed in dissociative double photoionization of NO2 are interpreted by comparison with the calculations and charge transfer results. The N- and O-Auger spectra of NO2 have been recorded and some of the 40 features observed have been assigned, confirming and improving the spectrum of NO2+2.Type of Medium: Electronic ResourceURL: -
11Tomlinson, D. R. ; Burnand, R. C. ; Price, S. A.
Oxford, UK : Blackwell Publishing Ltd
Published 2003Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Dysfunctional switches in neuronal phenotype are at the root of diabetic neuropathy and many aspects of neuronal phenotype are maintained by neurotrophic influences. Thus the failure of these and their mediating signals are fundamental to understanding and controlling the condition. In experimental diabetes, failure of the C fiber phenotype is secondary to reduced neurotrophic regulation by nerve growth factor (NGF). We have performed gene array profiling to identify candidate genes for other neurotrophic factors. This reveals sonic hedgehog as a neurotrophic regulator, with the capacity to maintain nerve conduction velocity in the normal range and to maintain normal gene expression for a range of influential candidate genes. As all known targets for sonic hedgehog are transcription dependent, this implicates impaired gene expression, rather than disturbed physiology, in the nerve conduction defects of diabetes and suggest the most successful method of prevention of the condition.Type of Medium: Electronic ResourceURL: -
12Evans, J. S. O. ; Francis, R. J. ; O'Hare, D. ; Price, S. J. ; Clark, S. M. ; Flaherty, J. ; Gordon, J. ; Nield, A. ; Tang, C. C.
[S.l.] : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The design and implementation of a pressure cell for the study of hydrothermal reactions by in situ energy dispersive x-ray diffraction is described. The cell permits the study of both the kinetics and mechanism of formation of a wide range of important solid-state compounds such as zeolites and other microporous solids. Reactions can be studied over a wide range of temperature (5–230 °C) and autogenous pressure [0–400 psi (gauge)] conditions. The use of this apparatus is illustrated by a study on the synthesis of a microporous tin chalcogenide phase performed on Station 9.7 of the UK Synchrotron Radiation Source. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The minima in the electrostatic energy, for accessible orientations, have been located for the s-tetrazine and benzene dimers and the 1:1 complexes of s-tetrazine with hydrogen chloride, water, acetylene, and benzene, and of benzene with acetylene, anthracene, and perylene. The minima give reasonably successful predictions of the structures of these van der Waals molecules, demonstrating the importance of the electrostatic interactions in these systems. The electrostatic energy was calculated using sets of distributed multipoles obtained from ab initio wave functions of the monomers. This method is contrasted with empirical point charge and central multipole models for the electrostatic energy. It is shown that the simple models for the electrostatic interactions can give qualitatively misleading results for aromatic systems.Type of Medium: Electronic ResourceURL: -
16Price, S. D. ; Eland, J. H. D. ; Fournier, P. G. ; Fournier, J. ; Millie, P.
College Park, Md. : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Energies of the electronic states of the triatomic dication N2O2+ in the Franck–Condon zone of neutral N2O have been determined by a combination of (1) double charge transfer spectroscopy to locate singlet states, (2) photoionization measurements to locate the lowest triplet state, and (3) configuration-interaction calculations to identify the states and to predict the energies of other triplets. It seems likely that two distinct charge separation reactions compete in the relatively slow decay of the N2O2+ ground state.Type of Medium: Electronic ResourceURL: -
17ROSE, A. G. ; TIMME, A. H. ; PRICE, S. K. ; EMMS, M. ; DALE, J.
Oxford, UK : Blackwell Publishing Ltd
Published 1979Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The changes of myospherulosis were observed in masses from the buttocks of three patients. Ultrastructural examination of parent bodies and spherules from two patients revealed some spherules to contain dense bodies and filaments. Spherules had a double electron dense wall: the outer layer had a thickness corresponding to that of a cell membrane. Incubation of packed red blood cells with tetracycline ointment produced a similar electron dense deposit on the inner aspect of the cell membrane of the erythrocytes. No filaments or parent bodies were seen. Our findings support the hypothesis that myospherulosis represents altered red blood cells. The filaments seen in our patients may represent polymers of haemoglobin. It is suggested that parent bodies may be derived from histiocytes.Type of Medium: Electronic ResourceURL: -
18LEARMONTH, G. M. ; PRICE, S. K. ; VISSER, A. E. ; EMMS, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Two cases of papillary and cystic neoplasm of the pancreas (PCN) occurring in 17 and 21 year old women are reported with ultrastructural and immunohistochemical findings. A review of the English literature shows that although potentially malignant, PCN, which occurs mainly in young women, is amenable to surgical cure. The significance of large PAS positive and alpha-1-antitrypsin positive tumour granules; the lack of specificity of alpha-1-antitrypsin for pancreatic acinar cells; the possibility of acinar differentiation of PCN; and its separation from pancreaticoblastoma are discussed.Type of Medium: Electronic ResourceURL: -
19Curtis, M. A. ; Sterne, J. A. C. ; Price, S. J. ; Griffiths, G. S. ; Coulthurst, S. K. ; Wilton, J. M. A. ; Johnson, N. W.
Oxford, UK : Blackwell Publishing Ltd
Published 1990Staff ViewISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Gingival crevicular fluid (GCF) is a promising source for markers of destructive periodontal diseases activity. As the initial stage of a longitudinal study into the characterization of disease markers, GCF sampled from 104 sites in 74 adolescents was examined via sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS/PAGE). In this population, which had varying degrees of gingivitis but little evidence of destructive periodontitis, there was a highly homologous GCF protein profile. The plasma components, albumin, transferrin and IgG, were major constituents of all samples. In addition, a second group of non-plasma derived proteins, with molecular weights 37 kDa, 47 kDa, 57 kDa and 59 kDa, was also commonly detected. The high frequency of occurrence of these components suggests that they may represent products of normal turnover of the periodontal tissues. Analysis of GCF sampled from patients with progressing destructive disease revealed a different SDS/PAGE profile particularly with respect to proteins of non-plasma origin. It is anticipated that the major metabolic changes which accompany the destruction of the tissues during future disease episodes in the adolescent study population will be discernible as alterations to the GCF protein profile.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0022-5185Topics: Theology and Religious StudiesNotes: AUTHORS AND BOOKS REVIEWED OR NOTICEDURL: