Search Results - (Author, Cooperation:S. Norman)

Endler, Norman S.

Unknown

682 S.

English

Matloff, Norman S. [Verfasser] 1948-

Book

xxxviii, 489 Seiten, Illustrationen, Diagramme

9781498710916, 9781138066465

Texts in statistical science

English

Includes bibliographical references, Im Buch ist die ISBN der Hardbackausgabe fälschlich als: 978-1-138-06656-5 angegeben

book

1983

Postindustrielle Gesellschaft ; Künstliche Intelligenz ; Personal Computer ; Planung ; Elektronische Datenverarbeitung ; Elektrotechnische Industrie ; Energiewirtschaft ; Beruf ; Berufschance ; Karriere ; Informationsberuf ; Neuer Beruf ; Prognose

English

2018-01-05

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Geosciences

Computer Science

Medicine

Natural Sciences in General

Physics

Astronomy

2018-07-27

American Association for the Advancement of Science (AAAS)

0036-8075

1095-9203

Biology

Chemistry and Pharmacology

Geosciences

Computer Science

Medicine

Natural Sciences in General

Physics

Astronomy

2015-05-21

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Cell Lineage ; Endothelial Cells/cytology/metabolism ; Female ; Heart/physiology/physiopathology ; Homeodomain Proteins/metabolism ; *Lymphangiogenesis ; Lymphatic Vessels/*cytology/*injuries/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Myocardial Infarction/metabolism/physiopathology ; Myocardium/*cytology/metabolism ; Proto-Oncogene Proteins c-vav/metabolism ; Receptor, Macrophage Colony-Stimulating Factor/metabolism ; Receptor, Platelet-Derived Growth Factor beta/metabolism ; Receptor, TIE-2/metabolism ; Spatio-Temporal Analysis ; Tumor Suppressor Proteins/deficiency/metabolism ; Vascular Endothelial Growth Factor C/metabolism ; Veins/cytology ; Yolk Sac/cytology

1365-2133

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1365-2133

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1573-3246

Springer Online Journal Archives 1860-2000

Psychology

Electronic Resource

article

2004

Empirische Untersuchung ; Interkulturelle Kommunikation ; Soziale Interaktion ; Ausländer ; Student ; USA

International education, Bd. 33 (2004) H. 2, S. 5-18, 0160-5429

English

Literaturangaben 32

book

1984

Englischunterricht ; Bild ; Logopädie

English

Literaturangaben S. 215 - 217

1471-4159

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Abstract: Gangliosides stimulate the hydrolysis of glucosylceramide (GlcCer), their precursor, and therefore may lower the level of cellular GlcCer and exert a feedback control effect to slow the formation of gangliosides. Tests were made to see if a similar effect on GlcCer levels can be exerted by the action of gangliosides on GlcCer synthesis. Using a new assay procedure, we showed that gangliosides do inhibit the synthase in brain membranes quite effectively, the most active being those lipids with more sugar and sialic acid moieties. Mice injected with a mixture of brain gangliosides for 5 days were found to have a lower level of ceramide:UDP-Glc glucosyl-transferase activity in brain, liver, and kidney. The inhibition seems to be exerted by competition for the active site and binding to effector site(s) on the enzyme. It is possible that the reported therapeutic actions of gangliosides on the nervous system are, in part, the result of lowered levels of GlcCer. Malignant tumors shed gangliosides into the extracellular fluid, which are believed to block the generation of antibodies by the host's immunodefense system; this effect also may be due, in part, to reduction in the GlcCer level of immunogenic cells. A new finding is that a ceramide containing phytosphingosine is a markedly better substrate for GlcCer synthase than one containing the more common base.

Electronic Resource

1471-0528

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Objective To compare the effect of intramuscular Syntometrine and Syntocinon in the management of the third stage of labour.Design A randomised double blind prospective study.Setting Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Hong Kong.Subjects One thousand consecutive patients with singleton pregnancy and vaginal delivery in February and March 1993.Results The use of Syntometrine in the management of the third stage not only reduced the blood loss after delivery but was associated with a 40% reduction in the risk of postpartum haemorrhage (odds ratio 0.60; 95% CI 0.21–0.88), and the need for repeat oxytocic injections (odds ratio of 0.63; 95% CI 0.44–089). The two drugs did not differ in their effect on the duration of the third stage. However, the incidence of manual removal of the placenta was higher when Syntometrine was used (odds ratio 3.7; 95% CI 1.03–123), although the overall incidence remained low. Side effects from both drugs, such as nausea, vomiting, headache and hypertension, were uncommon.Conclusion Intramuscular Syntometrine is a better choice than Syntocinon in the management of the third stage of labour.

Electronic Resource

1471-0528

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Objective To investigate the attitude of consultant gynaecologists and general practitioners to various aspects of hormone replacement therapy and to compare the findings in these two groups.Design Anonymous postal survey of 589 general practitioners and 998 consultant gynaecologists; 373 (63%) and 655 (66%) valid replies, respectively, were received.Main outcome measures Views on universal treatment of eligible women, indications for hormone replacement therapy, prescribing practice, pretreatment investigation, monitoring, and contraindications to treatment.Results More consultants (64%) than general practitioners (56%) thought hormone replacement therapy should be offered to all eligible women, with a significant trend against treatment amongst more senior consultants. Most practitioners were prepared to offer treatment before the cessation of menstruation, but only 27% of consultants and 11% of general practitioners recommended indefinite treatment. Most limited treatment to less than 10 years. Menopausal symptoms, premature natural and surgical menopause, and a family history of osteoporosis were regarded as indications for treatment, but less than half felt established osteoporosis an indication. Hormone replacement therapy was judged to reduce the risk of ischaemic heart disease and osteoporosis by both groups but there was less consensus on the prevention of cerebrovascular accident. In general, consultants had more faith in hormone replacement therapy as prophylaxis. One-quarter of consultants said that hormone replacement therapy should be initiated by consultants. Only 4% of general practitioners shared this view. About 30% of both groups required mammography, but less than 10% required sophisticated tests. A range of common cardiovascular conditions were regarded as contraindications, although general practitioners were more likely to regard thrombosis and cerebrovascular accident as contraindications. Breast cancer and a family history of breast cancer were regarded with suspicion by both groups.Conclusions Practitioners were positively inclined to hormone replacement therapy, but many were unconvinced of its chronic use and use in those with cardiovascular conditions. There were differences in views as to who should initiate therapy.

Electronic Resource

1471-0528

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Objective— To estimate the local incidence of ectopic pregnancy and to review the management of ectopic pregnancy with reference to those misdiagnosed at presentation. To establish management guidelines to be applied to all possible ectopic pregnancies.Design— A review of all ectopic pregnancies presenting over a 2-year period, and of emergency gynaecological admissions during 4 months.Setting— A teaching hospitalResults— The local rate of ectopic pregnancy was similar to that seen in other UK studies. Nineteen (13%) women with ectopic pregnancies were sent home with an incorrect diagnosis. Eight were recalled but eight required emergency admission and one died at home. Undue confidence in ultrasound reports and failure to follow up inconclusive histology results were a feature in cases where patients were not recalled. A set of simple management guidelines has been drawn up. Amongst general gynaecological admissions 1 in 12 of all first trimester complications was an ectopic pregnancy. Amongst apparently true uterine miscarriages 20% of histological examinations were inconclusive and histology and ultrasound examinations failed to confirm a uterine miscarriage in 14% of apparently true missed miscarriages.Conclusions— Ectopic pregnancy is common amongst first trimester complications. Adherence to simple management guidelines would minimize the number of patients requiring emergency admission, though up to 20% of patients with apparently true uterine miscarriages would also require further investigation.

Electronic Resource

1550-7408

Blackwell Publishing Journal Backfiles 1879-2005

Biology

The morphology of spore germination in Didymium nigripes was studied using scanning electron microscopy and Nomarski phase optics. First, the outer spore wall splits, revealing a fibrillar inner wall. Remnants of the inner wall continue to cover the newly emerged amoeba. A single nucleus and a prominent vacuole are visible throughout germination. Germination is more rapid in glucose-peptone-yeast extract than in phosphate buffer. Germination is completely inhibited at 4°C, and is very slow at 18°C. Germination is most rapid at 26°C; at 21°C or 32°C it is slightly slower. Germination is reversibly inhibited by 20 μ/ml cycloheximide, but not by 200 μ/ml 5-fluoro uracil or 200 μ/ml proflavin. It is completely inhibited by 10-3 M Na azide.

Electronic Resource

1550-7408

Blackwell Publishing Journal Backfiles 1879-2005

Biology

For development of flagella by myxamoebae of the true slime mold, Didymium nigripes, optimal results were obtained when they were incubated in 0.05 M NaHCOa (pH 9.1). Streptomycin inhibited flagella formation in pH 6.2 phosphate buffer but had no effect in NaHC03. The time necessary for 50% of the population of myxamoebae to become flagellated was independent of the concentration of myxamoebae; hence, the morphogenesis probably follows first-order kinetics. The acquisition of flagella was divisible into 4 stages by means of time-lapse cinephotomicroscopy: an ameboid stage, a stage of morphogenesis, an ameboid-flagellate stage, and a free-swimming flagellate stage. At least 90% of the population developed flagella within 60 min. under optimal conditions. The flagellar apparatus consists of a long and a short flagellum, each arising from a granule in the blepharo-plast. The blepharoplast is connected to the nucleus by a rhizoplast.

Electronic Resource

1471-4159

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Abstract: Intact brain and brain homogenates readily form free fatty acids and ceramides, even in the cold during subcellular isolation procedures. The fatty acid formation is slightly stimulated by chelators and might be due to phospholipid hydrolysis by lysosomal phospholipases. The ceramide formation is accompanied by loss of sphingomyelin and is apparently due to the action of neutral, metal ion-activated sphingomyelinase. The latter reaction is inhibited by EDTA whereas both degradative processes are inhibited by mercuriphenylsulfonate, the thiol-reacting inhibitor. Cerebroside does not seem to be a source of accumulated ceramide.

Electronic Resource

1077-3118

AIP Digital Archive

Physics

Superluminescent diodes with high output power (10 mW at 175 mA), wide spectral width (28 nm), low spectral modulation depth (〈15%), wide frequency modulation bandwidth (570 MHz), and high single-mode fiber coupling efficiency (40%) are reported. The structure is based on a buried crescent laser structure with an antireflection coating and a "short-circuit'' absorber to suppress lasing.

Electronic Resource

1077-3118

AIP Digital Archive

Physics

A superluminescent diode (SLD) based on a proven high power, high efficiency "window-'' type index-guided buried heterostructure laser is demonstrated. Lasing is suppressed for SLD operation by antireflection coating and by incorporating an unpumped absorber section. The resulting device emits high optical power (14 mW) in the SLD mode at very low injection current (50 mA). The spectral modulation depth is below 14% over the entire emission spectral bandwidth of 20 nm, with a symmetrical beam divergence (20°×40°) and a stable transverse mode.

Electronic Resource