Search Results - (Author, Cooperation:S. Narumiya)
-
1H. Mizuno ; C. Higashida ; Y. Yuan ; T. Ishizaki ; S. Narumiya ; N. Watanabe
American Association for the Advancement of Science (AAAS)
Published 2010Staff ViewPublication Date: 2010-12-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Actin Cytoskeleton/chemistry/*metabolism/ultrastructure ; Actins/chemistry/*metabolism ; Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/metabolism ; Animals ; Carrier Proteins/chemistry/*metabolism ; Fluorescence Polarization ; Mice ; Models, Biological ; Profilins/metabolism ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Protein Structure, Secondary ; Rabbits ; Recombinant Fusion Proteins/chemistry/metabolism ; RotationPublished by: -
2R. Duffin ; R. A. O'Connor ; S. Crittenden ; T. Forster ; C. Yu ; X. Zheng ; D. Smyth ; C. T. Robb ; F. Rossi ; C. Skouras ; S. Tang ; J. Richards ; A. Pellicoro ; R. B. Weller ; R. M. Breyer ; D. J. Mole ; J. P. Iredale ; S. M. Anderton ; S. Narumiya ; R. M. Maizels ; P. Ghazal ; S. E. Howie ; A. G. Rossi ; C. Yao
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacterial Infections/genetics/immunology ; Dinoprostone/*immunology ; Gene Expression ; Humans ; Immunity, Innate ; Inflammation/drug therapy/*immunology/microbiology ; Interleukins/*immunology ; Intestines/*immunology/microbiology ; Lymphocytes/*immunology ; Mice ; Receptors, Prostaglandin E, EP4 Subtype/antagonists & ; inhibitors/genetics/*immunology ; Signal TransductionPublished by: -
3Nakagawa, O. ; Sasaki, Y. ; Tanaka, I. ; Usui, T. ; Sando, T. ; Muro, S. ; Mori, K. ; Itoh, H. ; Yoshimasa, T. ; Narumiya, S. ; Nakao, K.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. Prostacyclin elicits potent vasodilation and inhibition of platelet aggregation through binding to its membrane receptor. The impairment of prostacyclin receptor activity is implicated in various human cardiovascular diseases. We recently succeeded in molecular cloning of cDNA for the mouse, rat, and human prostacyclin receptors.2. In the present study, we examined the mRNA expression of the prostacyclin receptor in various rat tissues, and further investigated its gene expression in the hypertrophied cardiac ventricles of stroke-prone spontaneously hypertensive rats (SHRSP).3. In rat tissues, a single RNA band of approximately 3.7 kb was detected by northern blotting analysis using rat prostacyclin receptor cDNA as a probe. In adult Wistar rats, abundant mRNA expression was observed in the aorta, lung and spleen. Substantial amounts of transcript were expressed in the heart, pancreas, thymus and stomach. In contrast, no mRNA expression was detected in the brain.4. We further examined the mRNA expression of the prostacyclin receptor in the ventricles of 21 week old SHRSP. The ventricles of SHRSP showed remarkable hypertrophy, compared with those of age-matched Wistar-Kyoto (WKY) rats. The expression of prostacyclin receptor mRNA in the hypertrophied ventricles of SHRSP was almost equivalent to that in the ventricles of WKY.5. The present study revealed the gene expression of the prostacyclin receptor in various rat tissues, and further demonstrated the receptor mRNA expression in hypertensive cardiac hypertrophy. The present study will give a clue to investigate the clinical implication of prostacyclin and its receptor.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Sando, T. ; Usui, T. ; Tanaka, I. ; Mori, K. ; Sasaki, Y. ; Fukuda, Y. ; Namba, T. ; Sugimoto, Y. ; Ichikawa, A. ; Nakao, K. ; Narumiya, S.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Namba, T. ; Sugimoto, Y. ; Hirata, M. ; Hayashi, Y. ; Honda, A. ; Watabe, A. ; Negishi, M. ; Ichikawa, A. ; Narumiya, S.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XKeywords: [abr] PCR; polymerase chain reaction ; [abr] PG; prostaglandin ; [abr] PKC; protein kinase C ; [abr] TX; thromboxane ; [abr] TXA"2; thromboxane A"2Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
9Nakajima, M. ; Yamamoto, M. ; Ushikubi, F. ; Okuma, M. ; Fujiwara, M. ; Narumiya, S.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0898-6568Keywords: ADP-ribosylation ; GDP/GTP exchange proteins ; GTPase-activating protein ; effector domain ; epidermis differentiation inhibitor ; focal adhesion ; integrin ; low-molecular weight GTP_binding proteins ; ras superfamily ; stress fibreSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
11Taketo, M. ; Rochelle, J.M. ; Sugimoto, Y. ; Namba, T. ; Honda, A. ; Negishi, M. ; Ichikawa, A. ; Narumiya, S. ; Seldin, M.F.
Amsterdam : ElsevierStaff ViewISSN: 0888-7543Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
12Katsuyama, M. ; Sugimoto, Y. ; Namba, T. ; Irie, A. ; Negishi, M. ; Narumiya, S. ; Ichikawa, A.
Amsterdam : ElsevierStaff ViewISSN: 0014-5793Keywords: Prostacyclin ; Prostaglandin ; Prostanoid receptor ; Signal transductionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0014-5793Keywords: Neuropeptide ; Tyrosine phosphorylation ; rho p21Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Kumagai, N. ; Morii, N. ; Fujisawa, K. ; Yoshimasa, T. ; Nakao, K. ; Narumiya, S.
Amsterdam : ElsevierStaff ViewISSN: 0014-5793Keywords: Focal adhesion kinase ; Lysophosphatidic acid ; MAP-kinase ; Protein tyrosine kinase ; Protein tyrosine phosphorylation ; Signal transductionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
17Namba, T. ; Sugimoto, Y. ; Hirata, M. ; Hayashi, Y. ; Honda, A. ; Watabe, A. ; Negishi, M. ; Ichikawa, A. ; Narumiya, S.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XKeywords: [abr] PCR; polymerase chain reaction ; [abr] PG; prostaglandin ; [abr] PKC; protein kinase C ; [abr] TX; thromboxane ; [abr] TXA"2; thromboxane A"2Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Δ^1^2-prostaglandin J"2, an ultimate metabolite of prostaglandin D"2 exerting cell growth inhibitionStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
20Narumiya, S. ; Hirata, M. ; Nanba, T. ; Nikaido, T. ; Taniguchi, Y. ; Tagaya, Y. ; Okada, M. ; Mitsuya, H. ; Yodoi, J.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: