Search Results - (Author, Cooperation:S. Michels)

Showing 1 - 6 results of 6, query time: 0.20s Refine Results
  1. 1
    J. George ; J. S. Lim ; S. J. Jang ; Y. Cun ; L. Ozretic ; G. Kong ; F. Leenders ; X. Lu ; L. Fernandez-Cuesta ; G. Bosco ; C. Muller ; I. Dahmen ; N. S. Jahchan ; K. S. Park ; D. Yang ; A. N. Karnezis ; D. Vaka ; A. Torres ; M. S. Wang ; J. O. Korbel ; R. Menon ; S. M. Chun ; D. Kim ; M. Wilkerson ; N. Hayes ; D. Engelmann ; B. Putzer ; M. Bos ; S. Michels ; I. Vlasic ; D. Seidel ; B. Pinther ; P. Schaub ; C. Becker ; J. Altmuller ; J. Yokota ; T. Kohno ; R. Iwakawa ; K. Tsuta ; M. Noguchi ; T. Muley ; H. Hoffmann ; P. A. Schnabel ; I. Petersen ; Y. Chen ; A. Soltermann ; V. Tischler ; C. M. Choi ; Y. H. Kim ; P. P. Massion ; Y. Zou ; D. Jovanovic ; M. Kontic ; G. M. Wright ; P. A. Russell ; B. Solomon ; I. Koch ; M. Lindner ; L. A. Muscarella ; A. la Torre ; J. K. Field ; M. Jakopovic ; J. Knezevic ; E. Castanos-Velez ; L. Roz ; U. Pastorino ; O. T. Brustugun ; M. Lund-Iversen ; E. Thunnissen ; J. Kohler ; M. Schuler ; J. Botling ; M. Sandelin ; M. Sanchez-Cespedes ; H. B. Salvesen ; V. Achter ; U. Lang ; M. Bogus ; P. M. Schneider ; T. Zander ; S. Ansen ; M. Hallek ; J. Wolf ; M. Vingron ; Y. Yatabe ; W. D. Travis ; P. Nurnberg ; C. Reinhardt ; S. Perner ; L. Heukamp ; R. Buttner ; S. A. Haas ; E. Brambilla ; M. Peifer ; J. Sage ; R. K. Thomas
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-07-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Evolution ; Glyceraldehyde-3-phosphate dehydrogenase ; NMR ; Spinach ; Stereospecificity
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0740-5472
    Keywords:
    Alcoholic education ; alcoholism ; cognitive functioning ; prediction of learning ; within-treatment progress
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Althoff, H. ; Wehr, K. ; Michels, S. ; Prajsnar, D.
    Springer
    Published 1987
    Staff View
    ISSN:
    1437-1596
    Keywords:
    SIDS, toxic environmental factors ; Toxic metals, SIDS ; Respiratory infections, toxic environmental factors ; SIDS, toxische Umwelteinflüsse ; Toxische Metalle, SIDS ; Atemwegsinfekte, toxische Umwelteinflüsse
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Description / Table of Contents:
    Zusammenfassung Wegen der zunehmenden Diskussion über schädigende Umwelteinflüsse auch bei plötzlichen Kindstodesfällen (SIDS) wurden systematische chemisch-toxikologische Untersuchungen bei 54 obduzierten SIDS-Fällen und 2 altersgleichen Kontrollfällen durchgeführt. Die Analysen erstreckten sich auf die Konzentrationsbestimmung von Arsen, Blei, Cadmium, Quecksilber und Pentachlorphenol sowie andere organische Noxen in jeweils mehreren Organen und auf COHb im Leichenblut. Trotz variierender, teils stark streuender Analyseergebnisse lagen sowohl die gemessenen Extremwerte wie auch die arithmetischen Mittelwerte und die Medianwerte in einem Konzentrationsbereich, dem nach bisheriger Kenntnis keine toxikologische Relevanz zukommt. Es ließ sich nicht feststellen, daß bei Kindern aus städtischem Milieu eine höhere Belastung mit den untersuchten Schadstoffgruppen stattgefunden hatte als bei jenen aus ländlicher Region. Unterschiede zwischen SIDS-Fällen und Kontrollfällen bestanden nicht. Es ergab sich auch keine Korrelation zwischen den häufig morphologisch nachgewiesenen Atemwegsinfekten einschließlich einer Laryngitis und höheren Schadstoffkonzentrationen in den Organen der SIDS-Fälle.
    Notes:
    Summary The increasing number of discussions on the influence of toxic environmental factors, including SIDS, prompted systematic postmortem chemical-toxicological investigations to be carried out on 54 SIDS cases and 2 control cases of the same age group. Tissue levels of arsenic, lead, cadmium, mercury, and pentachlorphenol, as well as other organic noxious agents, were measured in several organs. In addition, the COHb concentrations were determined. In spite of the widely scattered values, the extreme levels measured and the arithmetic means and median averages of As, Pb, Cd, Hg, PCP, and COHb had no more range in concentrations than can be expected for toxic effects — according to present knowledge anyway. It was observed that infants from an urban environment showed no greater concentration of noxious agents than did infants from rural regions. There were also no differences between SIDS cases and the controls, nor was there a correlation between infections of the respiratory system that are often morphologically detected — including laryngitis — and higher concentrations of these agents in the organs of SIDS cases.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1432-1440
    Keywords:
    Immunomodulation ; Chronic renal failure ; Small peptides ; Middle molecules
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary A pentapeptide originally isolated by Abiko and coworkers from the ultrafiltrate of a uremic patient was synthesized and studied for its in vitro effects on normal human peripheral blood mononuclear cells. The SRBC-rosette forming capacity of T cells was significantly reduced after preincubation of the cells with the peptide, whereas the viability and the percentage of SRBC-receptor positive cells as determined with a monoclonal antibody remained unchanged. The PHA and ConA induced proliferation of T cells as well as the induction of suppressor cells by ConA were decreased, while the proliferative responses to PWM and specific antigens were enhanced. MLC experiments with separated and reconstituted lymphocyte populations pointed to the T cell as the main target. The data presented demonstrate that at least some of the effects described for so-called middle molecules are reproducible with this peptide at concentrations eventually occurring in patients with chronic renal failure.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses