Search Results - (Author, Cooperation:S. McLachlan)

Showing 1 - 10 results of 10, query time: 0.29s Refine Results
  1. 1
    Emma Undeman, Trevor N Brown, Michael S McLachlan and Frank Wania
    Institute of Physics (IOP)
    Published 2018
    Staff View
    Publication Date:
    2018-06-19
    Publisher:
    Institute of Physics (IOP)
    Print ISSN:
    1748-9318
    Electronic ISSN:
    1748-9326
    Topics:
    Biology
    Energy, Environment Protection, Nuclear Power Engineering
    Published by:
    http://www.iop.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    A. E. Locke ; B. Kahali ; S. I. Berndt ; A. E. Justice ; T. H. Pers ; F. R. Day ; C. Powell ; S. Vedantam ; M. L. Buchkovich ; J. Yang ; D. C. Croteau-Chonka ; T. Esko ; T. Fall ; T. Ferreira ; S. Gustafsson ; Z. Kutalik ; J. Luan ; R. Magi ; J. C. Randall ; T. W. Winkler ; A. R. Wood ; T. Workalemahu ; J. D. Faul ; J. A. Smith ; J. Hua Zhao ; W. Zhao ; J. Chen ; R. Fehrmann ; A. K. Hedman ; J. Karjalainen ; E. M. Schmidt ; D. Absher ; N. Amin ; D. Anderson ; M. Beekman ; J. L. Bolton ; J. L. Bragg-Gresham ; S. Buyske ; A. Demirkan ; G. Deng ; G. B. Ehret ; B. Feenstra ; M. F. Feitosa ; K. Fischer ; A. Goel ; J. Gong ; A. U. Jackson ; S. Kanoni ; M. E. Kleber ; K. Kristiansson ; U. Lim ; V. Lotay ; M. Mangino ; I. Mateo Leach ; C. Medina-Gomez ; S. E. Medland ; M. A. Nalls ; C. D. Palmer ; D. Pasko ; S. Pechlivanis ; M. J. Peters ; I. Prokopenko ; D. Shungin ; A. Stancakova ; R. J. Strawbridge ; Y. Ju Sung ; T. Tanaka ; A. Teumer ; S. Trompet ; S. W. van der Laan ; J. van Setten ; J. V. Van Vliet-Ostaptchouk ; Z. Wang ; L. Yengo ; W. Zhang ; A. Isaacs ; E. Albrecht ; J. Arnlov ; G. M. Arscott ; A. P. Attwood ; S. Bandinelli ; A. Barrett ; I. N. Bas ; C. Bellis ; A. J. Bennett ; C. Berne ; R. Blagieva ; M. Bluher ; S. Bohringer ; L. L. Bonnycastle ; Y. Bottcher ; H. A. Boyd ; M. Bruinenberg ; I. H. Caspersen ; Y. D. Ida Chen ; R. Clarke ; E. W. Daw ; A. J. de Craen ; G. Delgado ; M. Dimitriou ; A. S. Doney ; N. Eklund ; K. Estrada ; E. Eury ; L. Folkersen ; R. M. Fraser ; M. E. Garcia ; F. Geller ; V. Giedraitis ; B. Gigante ; A. S. Go ; A. Golay ; A. H. Goodall ; S. D. Gordon ; M. Gorski ; H. J. Grabe ; H. Grallert ; T. B. Grammer ; J. Grassler ; H. Gronberg ; C. J. Groves ; G. Gusto ; J. Haessler ; P. Hall ; T. Haller ; G. Hallmans ; C. A. Hartman ; M. Hassinen ; C. Hayward ; N. L. Heard-Costa ; Q. Helmer ; C. Hengstenberg ; O. Holmen ; J. J. Hottenga ; A. L. James ; J. M. Jeff ; A. Johansson ; J. Jolley ; T. Juliusdottir ; L. Kinnunen ; W. Koenig ; M. Koskenvuo ; W. Kratzer ; J. Laitinen ; C. Lamina ; K. Leander ; N. R. Lee ; P. Lichtner ; L. Lind ; J. Lindstrom ; K. Sin Lo ; S. Lobbens ; R. Lorbeer ; Y. Lu ; F. Mach ; P. K. Magnusson ; A. Mahajan ; W. L. McArdle ; S. McLachlan ; C. Menni ; S. Merger ; E. Mihailov ; L. Milani ; A. Moayyeri ; K. L. Monda ; M. A. Morken ; A. Mulas ; G. Muller ; M. Muller-Nurasyid ; A. W. Musk ; R. Nagaraja ; M. M. Nothen ; I. M. Nolte ; S. Pilz ; N. W. Rayner ; F. Renstrom ; R. Rettig ; J. S. Ried ; S. Ripke ; N. R. Robertson ; L. M. Rose ; S. Sanna ; H. Scharnagl ; S. Scholtens ; F. R. Schumacher ; W. R. Scott ; T. Seufferlein ; J. Shi ; A. Vernon Smith ; J. Smolonska ; A. V. Stanton ; V. Steinthorsdottir ; K. Stirrups ; H. M. Stringham ; J. Sundstrom ; M. A. Swertz ; A. J. Swift ; A. C. Syvanen ; S. T. Tan ; B. O. Tayo ; B. Thorand ; G. Thorleifsson ; J. P. Tyrer ; H. W. Uh ; L. Vandenput ; F. C. Verhulst ; S. H. Vermeulen ; N. Verweij ; J. M. Vonk ; L. L. Waite ; H. R. Warren ; D. Waterworth ; M. N. Weedon ; L. R. Wilkens ; C. Willenborg ; T. Wilsgaard ; M. K. Wojczynski ; A. Wong ; A. F. Wright ; Q. Zhang ; E. P. Brennan ; M. Choi ; Z. Dastani ; A. W. Drong ; P. Eriksson ; A. Franco-Cereceda ; J. R. Gadin ; A. G. Gharavi ; M. E. Goddard ; R. E. Handsaker ; J. Huang ; F. Karpe ; S. Kathiresan ; S. Keildson ; K. Kiryluk ; M. Kubo ; J. Y. Lee ; L. Liang ; R. P. Lifton ; B. Ma ; S. A. McCarroll ; A. J. McKnight ; J. L. Min ; M. F. Moffatt ; G. W. Montgomery ; J. M. Murabito ; G. Nicholson ; D. R. Nyholt ; Y. Okada ; J. R. Perry ; R. Dorajoo ; E. Reinmaa ; R. M. Salem ; N. Sandholm ; R. A. Scott ; L. Stolk ; A. Takahashi ; F. M. Van't Hooft ; A. A. Vinkhuyzen ; H. J. Westra ; W. Zheng ; K. T. Zondervan ; A. C. Heath ; D. Arveiler ; S. J. Bakker ; J. Beilby ; R. N. Bergman ; J. Blangero ; P. Bovet ; H. Campbell ; M. J. Caulfield ; G. Cesana ; A. Chakravarti ; D. I. Chasman ; P. S. Chines ; F. S. Collins ; D. C. Crawford ; L. A. Cupples ; D. Cusi ; J. Danesh ; U. de Faire ; H. M. den Ruijter ; A. F. Dominiczak ; R. Erbel ; J. Erdmann ; J. G. Eriksson ; M. Farrall ; S. B. Felix ; E. Ferrannini ; J. Ferrieres ; I. Ford ; N. G. Forouhi ; T. Forrester ; O. H. Franco ; R. T. Gansevoort ; P. V. Gejman ; C. Gieger ; O. Gottesman ; V. Gudnason ; U. Gyllensten ; A. S. Hall ; T. B. Harris ; A. T. Hattersley ; A. A. Hicks ; L. A. Hindorff ; A. D. Hingorani ; A. Hofman ; G. Homuth ; G. K. Hovingh ; S. E. Humphries ; S. C. Hunt ; E. Hypponen ; T. Illig ; K. B. Jacobs ; M. R. Jarvelin ; K. H. Jockel ; B. Johansen ; P. Jousilahti ; J. W. Jukema ; A. M. Jula ; J. Kaprio ; J. J. Kastelein ; S. M. Keinanen-Kiukaanniemi ; L. A. Kiemeney ; P. Knekt ; J. S. Kooner ; C. Kooperberg ; P. Kovacs ; A. T. Kraja ; M. Kumari ; J. Kuusisto ; T. A. Lakka ; C. Langenberg ; L. Le Marchand ; T. Lehtimaki ; V. Lyssenko ; S. Mannisto ; A. Marette ; T. C. Matise ; C. A. McKenzie ; B. McKnight ; F. L. Moll ; A. D. Morris ; A. P. Morris ; J. C. Murray ; M. Nelis ; C. Ohlsson ; A. J. Oldehinkel ; K. K. Ong ; P. A. Madden ; G. Pasterkamp ; J. F. Peden ; A. Peters ; D. S. Postma ; P. P. Pramstaller ; J. F. Price ; L. Qi ; O. T. Raitakari ; T. Rankinen ; D. C. Rao ; T. K. Rice ; P. M. Ridker ; J. D. Rioux ; M. D. Ritchie ; I. Rudan ; V. Salomaa ; N. J. Samani ; J. Saramies ; M. A. Sarzynski ; H. Schunkert ; P. E. Schwarz ; P. Sever ; A. R. Shuldiner ; J. Sinisalo ; R. P. Stolk ; K. Strauch ; A. Tonjes ; D. A. Tregouet ; A. Tremblay ; E. Tremoli ; J. Virtamo ; M. C. Vohl ; U. Volker ; G. Waeber ; G. Willemsen ; J. C. Witteman ; M. C. Zillikens ; L. S. Adair ; P. Amouyel ; F. W. Asselbergs ; T. L. Assimes ; M. Bochud ; B. O. Boehm ; E. Boerwinkle ; S. R. Bornstein ; E. P. Bottinger ; C. Bouchard ; S. Cauchi ; J. C. Chambers ; S. J. Chanock ; R. S. Cooper ; P. I. de Bakker ; G. Dedoussis ; L. Ferrucci ; P. W. Franks ; P. Froguel ; L. C. Groop ; C. A. Haiman ; A. Hamsten ; J. Hui ; D. J. Hunter ; K. Hveem ; R. C. Kaplan ; M. Kivimaki ; D. Kuh ; M. Laakso ; Y. Liu ; N. G. Martin ; W. Marz ; M. Melbye ; A. Metspalu ; S. Moebus ; P. B. Munroe ; I. Njolstad ; B. A. Oostra ; C. N. Palmer ; N. L. Pedersen ; M. Perola ; L. Perusse ; U. Peters ; C. Power ; T. Quertermous ; R. Rauramaa ; F. Rivadeneira ; T. E. Saaristo ; D. Saleheen ; N. Sattar ; E. E. Schadt ; D. Schlessinger ; P. E. Slagboom ; H. Snieder ; T. D. Spector ; U. Thorsteinsdottir ; M. Stumvoll ; J. Tuomilehto ; A. G. Uitterlinden ; M. Uusitupa ; P. van der Harst ; M. Walker ; H. Wallaschofski ; N. J. Wareham ; H. Watkins ; D. R. Weir ; H. E. Wichmann ; J. F. Wilson ; P. Zanen ; I. B. Borecki ; P. Deloukas ; C. S. Fox ; I. M. Heid ; J. R. O'Connell ; D. P. Strachan ; K. Stefansson ; C. M. van Duijn ; G. R. Abecasis ; L. Franke ; T. M. Frayling ; M. I. McCarthy ; P. M. Visscher ; A. Scherag ; C. J. Willer ; M. Boehnke ; K. L. Mohlke ; C. M. Lindgren ; J. S. Beckmann ; I. Barroso ; K. E. North ; E. Ingelsson ; J. N. Hirschhorn ; R. J. Loos ; E. K. Speliotes
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-02-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adipogenesis/genetics ; Adiposity/genetics ; Age Factors ; *Body Mass Index ; Continental Population Groups/genetics ; Energy Metabolism/genetics ; Europe/ethnology ; Female ; Genetic Predisposition to Disease/genetics ; *Genome-Wide Association Study ; Glutamic Acid/metabolism ; Humans ; Insulin/metabolism/secretion ; Male ; Obesity/*genetics/*metabolism ; Polymorphism, Single Nucleotide/genetics ; Quantitative Trait Loci/genetics ; Synapses/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    ISSN:
    0921-4526
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4526(94)91709-4

    Articles: DFG German National Licenses
  4. 4
    McLACHLAN, A. J. ; McLACHLAN, S. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1976
    Staff View
    ISSN:
    1365-2427
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    An attempt is made to illustrate some of the principles of early development of muds in two contrasting lake basins which were devoid of vegetation cover before filling. Essentially the changes involve the dispersion and redistribution of particles in the newly flooded lake bottom. Field and laboratory observations are presented to demonstrate the interaction that exists between water chemistry, wave erosion and the burrowing activity of mud-dwelling insect larvae, and the effect of these factors on particle size sorting in the substrate. These characteristic changes in the mud during filling are compared with post-filling stage developments in which the role of extraneous material, including organic matter, may predominate.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2427.1976.tb01591.x

    Articles: DFG German National Licenses
  5. 5
    THOMPSON, P. M. ; McLACHLAN, S. M. ; PARKES, A. ; CLARK, F. ; HOWEL, D. ; SMITH, B. REES

    Oxford, UK : Blackwell Publishing Ltd
    Published 1983
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Thyroglobulin autoantibodies synthesized by Hashimoto lymphocytes in culture and present in serum have been analysed in terms of their IgG subclass distribution. The autoantibodies produced in vitro were frequently IgG4 or IgG1. whether pokeweed mitogen or Epstein-Barr virus was used to stimulate the cultures, and the subclass distribution of these thyroglobulin antibodies was similar to that observed in the patients'serum. It appears therefore that the antibodies synthesized in vitro in response to polyclonal B-cell activators resemble those produced in vivo, and it seems likely that both pokeweed mitogen and Epstein-Barr virus influence the same B-cell precursors of autoantibody-synthesizing celts, albeit by different mechanisms.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1983.tb00848.x

    Articles: DFG German National Licenses
  6. 6
    McLACHLAN, S. M. ; BIRD, A. G. ; WEETMAN, A. P. ; SMITH, REES ; HALL, R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1981
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Plaque assays have been used to study thyroglobulin autoantibody synthesis and total immunoglobulin production by cultures of peripheral blood lymphocytes from patients with Hashimoto's thyroiditis. Freshly isolated Hashimoto or normal lymphocytes contained small numbers (7–1300) of total IgG plaque-forming cells (PFC) and total IgM PFC, but specific thyroglobulin antibody PFC was undetectable. After 5–8 days' culture with pokeweed mitogen (PWM), total IgG and IgM PFC were markedly increased to a geometric mean of 10, 140 (8414–12,220) IgG PFC and 3450 (1663–7534) IgM PFC per 106 cultured lymphocytes (95% confidence limits in parentheses). Furthermore, a mean of 63 (22–287) specific IgG thyroglobulin antibody PFC per 106 lymphocytes were detectable in cultures of Hashimoto lymphocytes. The IgG thyroglobulin antibody PFC were stimulated by Epstein-Barr virus (EBV) infection, suggesting that EBV infection may be useful in obtaining monoclonal thyroid autoantibodies.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1981.tb00560.x

    Articles: DFG German National Licenses
  7. 7
    MCLACHLAN, S. M. ; SMITH, B. REES ; PETERSEN, V. B. ; DAVIES, T. F. ; HALL, R.

    [s.l.] : Nature Publishing Group
    Published 1977
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Fig. 1 Kinetics of IgG production by peripheral blood lymphocytes. Lymphocytes were separated on a Ficoll-Hypaque gradient19 and washed three times; the yield from heparinised blood averaged 80%. The cells were incubated at 1.0-1.5 xlO7 per ml in 1 ml aliquots in Marbrook flasks with an outer ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/270447a0

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0165-1161
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0165-1161(80)90194-6

    Articles: DFG German National Licenses
  9. 9
    McLachlan, A. J. ; McLachlan, S. M.
    Springer
    Published 1969
    Staff View
    ISSN:
    1573-5117
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Description / Table of Contents:
    Zusammenfassung Ende 1967 wurden die Bodenfauna und die Sedimente des Chilwa Sees, Malawi, untersucht, als es den Schein hatte, daβ der See austrocknen würde. Die Bodenfauna war gering in Anzahl und an Arten, als das Niveau des Sees niedrig war, aber Überbleibsel von Tieren deuteten auf einer reicheren Fauna, einschlieβlich einer groβen Molluskengemeinschaft, wenn bei Jahresanfang das Niveau des Sees höher war. Charakteristisch für die Sedimente waren ein hoher pH-Wert, Leitfähigkeit, CaCO3 und austauschbares Na +. Weil der Boden überschwemmt gewesen war, zeigten die Analysen-resultate Änderungen im Schlamm nach Bloβstellung, nämlich Verlust von organischer Substanz, Phosphor und austauschbarem Na +. Es wird angenommen, daβ eher die Physische Eigenschaft des Substrats als der Salzgehalt die Ursache für den niedrigen benthischen Wert ist. Mögliche Probleme der Wiederbesiedlung werden diskutiert.
    Notes:
    Summary A study of the bottom fauna and sediments of Lake Chilwa, Malawi, was carried out in late 1967 when the lake appeared to be drying out. The mud fauna at low lake level was poor, while skeletal remains suggested a more diverse and richer fauna, including a large mollusc community, when the level was higher earlier in the year. Sediments were characterised by high values for pH, conductivity, CaCO3 and exchangeable Na +. As the soils had been inundated at some stage, the results of analyses indicated the changes undergone by muds on exposure, namely loss of organic matter, phosphorus and exchangeable Na +. The physical nature of the substrate at low lake level rather than increased salinity is thought to have been largely responsible for the low benthic values. Potential problems of faunal re-colonisation are considered.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00045400

    Articles: DFG German National Licenses
  10. 10
    McLachlan, S. M.
    Springer
    Published 1971
    Staff View
    ISSN:
    1573-5117
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Description / Table of Contents:
    Résumé On a procédé à la réalisation de deux expériences visant à déterminer la vitesse de libération des ions dans l'eau d'un lac à partir d'herbe sèche (appartenant principalement à l'espèce Eragrostis) et de crottin d'éléphant, d'impala et de buflle. Par ordre décroissant, on mesure les vitesses de libération des ions les plus grands pour PO4 3- et K+, et ensuite pour NO3 - et Ca2+ + Mg2+; Na+ manifeste l'augmentation de concentration la plus faible. En règle générale, le crottin formé à partir d'herbe a libéré les ions à vitesse plus grande que l'herbe elle-même; les résultats sont interprétés par rapport à des analyses de cendre d'herbe et de crottin. On a cherché à estimer l'importance que peuvent présenter, pour le lac Kariba, la libération de ces éléments nutritifs après immersion dans des conditions naturelles.
    Notes:
    Summary Two experiments were carried out to determine the rate of release of ions to lake water from dry grass (largely Eragrostis species) and dung from elephant, impala and buffalo. The ions released most rapidly were PO3 3- and K+, followed by NO3 - and Ca2+ + Mg2+; the smallest increase was shown by Na+. In general, dung derived from grass released ions more rapidly than grass itself; the results are discussed in relation to ash analyses of grass and dung. The possible importance to Lake Kariba of the nutrients released by grass and dung following immersion under natural conditions is considered.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00018817

    Articles: DFG German National Licenses