Search Results - (Author, Cooperation:S. Matoba)

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  1. 1
    S. Kuroki ; S. Matoba ; M. Akiyoshi ; Y. Matsumura ; H. Miyachi ; N. Mise ; K. Abe ; A. Ogura ; D. Wilhelm ; P. Koopman ; M. Nozaki ; Y. Kanai ; Y. Shinkai ; M. Tachibana
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-09-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Epididymis/abnormalities ; *Epigenesis, Genetic ; Female ; *Gene Expression Regulation, Developmental ; Histones/*metabolism ; Jumonji Domain-Containing Histone Demethylases/genetics/*metabolism ; Male ; Methylation ; Mice ; Mice, Mutant Strains ; Mice, Transgenic ; Ovary/abnormalities/enzymology ; *Protein Processing, Post-Translational ; Sex Determination Processes/*genetics ; Testis/abnormalities/enzymology ; Uterus/abnormalities
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    T. Nakamura ; Y. J. Liu ; H. Nakashima ; H. Umehara ; K. Inoue ; S. Matoba ; M. Tachibana ; A. Ogura ; Y. Shinkai ; T. Nakano
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    5-Methylcytosine/*metabolism ; Animals ; Chromatin/chemistry/metabolism ; Cytosine/*analogs & derivatives/metabolism ; DNA Methylation ; DNA-Binding Proteins/metabolism ; Embryo, Mammalian/embryology/*metabolism ; Embryonic Development ; Female ; Genomic Imprinting/genetics ; Histones/*chemistry/*metabolism ; Lysine/chemistry/metabolism ; Male ; Methylation ; Mice ; Protein Binding/drug effects ; Proto-Oncogene Proteins/metabolism ; RNA, Long Noncoding ; RNA, Untranslated/genetics ; Repressor Proteins/*metabolism ; Spermatozoa/metabolism ; ras-GRF1/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    ISSN:
    1435-1803
    Keywords:
    Stretch ; non-ischemic stress ; post-ischemic dysfunction ; isolated perfused heart ; spontaneously hypertensive rat
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Objective: The aim of our study was to determine whether myocardial stretch (non-ischemic stress) could precondition isolated perfused hearts of both normotensive Wister-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR).Methods: The perfused hearts in Langendorff mode were subjected to 30 min of global no-flow ischemia followed by 30 min of reperfusion. Left ventricular developed pressure (LVDP) and end-diastolic pressure (LVEDP) were measured. In the control group, LVEDP was set at 10 mmHg. In the stretch group, LVEDP was increased to 30 or 60 mmHg for 5 min before 30 min of ischemia. In the ischemic preconditioning group, the hearts were exposed to two cycles of a 5-min period of ischemia before 30 min of ischemia. Myocardial lactate contents were measured at the baseline and at the end of the 60 mmHg stretch.Results: Hemodynamic parameters of LVDP and LVEDP at 30 min of reperfusion improved in the stretch group (LVEDP at 60 mmHg) and the ischemic preconditioning group. Coronary flow did not decrease during the stretch. Recovery of the coronary flow during reperfusion was better in the stretch and ischemic preconditioning groups. Postischemic contractile function was better in WKY rats than in SHR. Myocardial lactate contents at the end of 60 mmHg stretch were negligible. Conclusions: Myocardial stretch induced by increasing LVEDP preconditioned isolated perfused hearts of both WKY rats and SHR, via mechanisms not involving myocardial ischemia during stretch.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1435-1803
    Keywords:
    Key words Stretch – non-ischemic stress – post-ischemic dysfunction – isolated perfused heart – spontaneously hypertensive rat
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Objective: The aim of our study was to determine whether myocardial stretch (non-ischemic stress) could precondition isolated perfused hearts of both normotensive Wister-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). Methods: The perfused hearts in Langendorff mode were subjected to 30 min of global no-flow ischemia followed by 30 min of reperfusion. Left ventricular developed pressure (LVDP) and end-diastolic pressure (LVEDP) were measured. In the control group, LVEDP was set at 10 mmHg. In the stretch group, LVEDP was increased to 30 or 60 mmHg for 5 min before 30 min of ischemia. In the ischemic preconditioning group, the hearts were exposed to two cycles of a 5-min period of ischemia before 30 min of ischemia. Myocardial lactate contents were measured at the baseline and at the end of the 60 mmHg stretch. Results: Hemodynamic parameters of LVDP and LVEDP at 30 min of reperfusion improved in the stretch group (LVEDP of 60 mmHg) and the ischemic preconditioning group. Coronary flow did not decrease during the stretch. Recovery of the coronary flow during reperfusion was better in the stretch and ischemic preconditioning groups. Postischemic contractile function was better in WKY rats than in SHR. Myocardial lactate contents at the end of 60 mmHg stretch were negligible. Conclusions: Myocardial stretch induced by increasing LVEDP preconditioned isolated perfused hearts of both WKY rats and SHR, via mechanisms not involving myocardial ischemia during stretch.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses