Search Results - (Author, Cooperation:S. Malek)
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1G. Hatzivassiliou ; J. R. Haling ; H. Chen ; K. Song ; S. Price ; R. Heald ; J. F. Hewitt ; M. Zak ; A. Peck ; C. Orr ; M. Merchant ; K. P. Hoeflich ; J. Chan ; S. M. Luoh ; D. J. Anderson ; M. J. Ludlam ; C. Wiesmann ; M. Ultsch ; L. S. Friedman ; S. Malek ; M. Belvin
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Allosteric Regulation/drug effects ; Azetidines/pharmacology ; Cell Survival/drug effects ; Clinical Trials as Topic ; Crystallography, X-Ray ; Enzyme Activation/drug effects ; Feedback, Physiological/drug effects ; Genes, ras/*genetics ; HCT116 Cells ; Humans ; MAP Kinase Signaling System/drug effects ; Mitogen-Activated Protein Kinase Kinases/*antagonists & ; inhibitors/chemistry/metabolism ; Models, Molecular ; Neoplasms/*enzymology/*genetics/pathology ; Oncogene Protein p21(ras)/*genetics ; Phosphorylation/drug effects ; Phosphoserine/metabolism ; Piperidines/pharmacology ; Protein Kinase Inhibitors/*pharmacology ; Proto-Oncogene Proteins B-raf/genetics/*metabolismPublished by: -
2K. Rajagopalan, K. Chinnayakanahalli, C. Stockle, R. Nelson, C. Kruger, M. Brady, K. Malek, S. Dinesh, M.E. Barber, A. Hamlet, G. Yorgey, J. Adam
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-02-23Publisher: Wiley-BlackwellPrint ISSN: 0043-1397Electronic ISSN: 1944-7973Topics: Architecture, Civil Engineering, SurveyingGeographyPublished by: -
3Kerdja, T. ; Abdelli, S. ; Ghobrini, D. ; Malek, S.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Time- and space-resolved emission spectroscopy measurements were performed to investigate plasma dynamics during laser evaporation of a graphite target. The evolution of the velocity and the emission intensity of the excited species versus the distance and the pressure of the foreign gas are studied. The time-resolved emission intensity of C II* transition at 426.7 nm shows a double-peak structure, resulting from the stratification of the plasma into fast and slow components. Intense molecular emission is found to occur behind a front separating the plasma from the foreign gas. Two stages of expansion are found in the generated plume, the first one starting just after the laser irradiation, the second beginning some time later depending on the nature and the pressure of the foreign gas. The two stages are well described, using a viscous drag force model for the first one and a delayed ideal blast wave model for the second. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] THE insect epicuticle is known to be a complex structure, and the different views that have been put forward regarding its constitution have been difficult to reconcile. Wigglesworth has indicated the presence in Rhodnius1, Tenebrio2 and Periplaneta* of four epicuticular layers the cuticulin, ...Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The reason for this peculiarity has been examined during the course of an investigation into the cuticle of the scorpion Buthus quinquestriatus. Sheets of cuticles of this scorpion were subjected, after chitosan transformation, to different treatments: they were either stored in alcohol or washed ...Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] In the course of this work, it was found that J5-(3: 4-dihydroxyphenyl)propionic acid is present in the soft cuticle of ScMstocerca. This is important, for Hackman3 has suggested that the degradation of J5-(3: 4-dihydroxyphenyl)alanine may not proceed through the propionic derivative. In the full ...Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Résumé Le spermatophore chezPenaeus trisulcatus (Crustacés Décapodes) a une structure très compliquée. Sa dureté est dûe à un tannage phénolique qui ressemble à ce qui a lieu en général dans les cuticules d'arthropodes, bien qu'il n'implique pas de polyphénols libres.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The cuticle of the last nymphal instar of the desert locust, Schistocerca gregaria (Forskal), is pale and not amber-coloured, although, like that of the cockroach Periplaneta1, it appears to be phenolically tanned. It contains melanin only in well-defined patches. A critical study of melanin ...Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A similar membrane has been found between new and old cuticles of the locust Schistocerca gregaria at the time of moulting from nymph to adult and at all the preceding nymphal moults. Its origin has been studied in successive stages of the nymphal-adult moult. No trace of the membrane is seen until ...Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0942-0940Keywords: Cervical spondylosis myelopathy ; radiculopathy ; cervical laminectomy ; foramen magnum decompressionSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Twenty-six patients with cervical spondylosis and radiculomyelopathy were treated surgically. Eight patients had cervical laminectomy C1-C7, and 16 patients had complete cervical laminectomy C1-C7 with excision of the posterior rim of the foramen magnum. Follow-up of patients was from two months to eight years. The majority of patients improved markedly, and some of them had excellent results.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1573-5117Keywords: Lake Qarun ; Saline lakes ; Lakes environmentSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The lake situation and morphometry, climatic conditions, water balance and level, hydrology and hydrochemistry of lake Qarun were investigated. Salinity proved to be the most important factor affecting the lake water. Annual changes in salinity of the lake water were recorded. In 1906, the salinity ranged from 10.65 and 11.26‰, while in 1974–1976 it reached 30.9–34.5‰. The physico-chemical properties of the lake change greatly owing to climatic and anthropological factors.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1573-5117Keywords: Hydrobiology ; Plankton-BenthosSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Distribution and abundance of phyto-, zooplankton and benthic organisms in Lake Qarun were investigated during the period from January 1974 to December 1977. Average number of phytoplankton cells was 152,300 cells/L and its biomass was 0.365 g/C/m3; average number of zooplankton was 31.44 × 103/m3 and its biomass was 194.19 mg/m3. The average number of benthic fauna was 19889/m2 and its biomass was 400.22 g/m2 (dry wt.). Therefore, Lake Qarun may be considered as a highly eutrophic body of water. Freshwater planktonic species, that used to inhabit the lake, such as Diaptomus salinus and the cladoceran Moina salinarum, disappeared completely when the salinity of the lake water reached 30–34‰ However, some Rotatoria were able to withstand the high salinity. The new composition of the zooplankton community shows that the marine zooplankton species include not only Acartia latisetosa and Cirripedia nauplii, but also other species such as Polychaeta, Obelia medusae, etc. The benthos of Lake Qarun is characterised by an intensive growth of few species. The major part (i.e. 93.54% by weight) of bottom fauna in the lake is Mollusca, mainly Cerastoderma glaucum (69·84% by weight).Type of Medium: Electronic ResourceURL: