Search Results - (Author, Cooperation:S. M. Dymecki)

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  1. 1
    R. S. Ray ; A. E. Corcoran ; R. D. Brust ; J. C. Kim ; G. B. Richerson ; E. Nattie ; S. M. Dymecki
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-07-30
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Acidosis/physiopathology ; Action Potentials/drug effects ; Animals ; *Body Temperature Regulation ; Brain Stem/cytology ; Carbon Dioxide/blood ; Chemoreceptor Cells/*physiology ; Clozapine/*analogs & derivatives/metabolism/pharmacology ; G Protein-Coupled Inwardly-Rectifying Potassium Channels/metabolism ; Homeostasis ; Hydrogen-Ion Concentration ; Ligands ; Mice ; Mice, Transgenic ; Models, Neurological ; *Neural Inhibition ; Neurons/*physiology ; Receptors, G-Protein-Coupled/genetics/metabolism ; *Respiration ; Serotonin/*physiology
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Dymecki, S. M. ; Black, J. ; Nord, D. S. ; Jones, S. B. ; Baranowski, T. J. ; Brighton, C. T.

    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Published 1985
    Staff View
    ISSN:
    0736-0266
    Keywords:
    Electrical stimulation ; Osteogenesis ; Platinum ; Stainless steel ; Electrode materials ; Microtrauma ; Life and Medical Sciences
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Medicine
    Notes:
    Studies of electrical stimulation of osteogenesis with stainless steel electrodes have previously established a dose-response relationship between current and bone growth. Examination of the effect of different geometric current densities resulted in the conclusion that very little electrode surface area was involved in stimulation and led to the design of a multiport “distributive” cathode. A series of experiments were performed to extend these results to wire and multiport platinum electrodes. As before, a current-bone growth dose-response relationship was found. Peak bone growth was greater than for stainless steel. However, peak bone growth occurred at 2.0 μA (versus 20 μA for stainless steel). Correlation studies suggest that small changes in cathodic potential affect bone growth more than similar size changes in current. Finally, the generally benign local host response to platinum suggests that platinum may be a suitable materials for chronic indwelling anodes for stimulation of osteogenesis.
    Additional Material:
    8 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1002/jor.1100030201

    Articles: DFG German National Licenses