Search Results - (Author, Cooperation:S. Knight)
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1Abigail S. Knight, Josefin Larsson, Jing M. Ren, Raghida Bou Zerdan, Shay Seguin, Remy Vrahas, Jianfang Liu, Gang Ren and Craig J. Hawker
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-01-18Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
2A. D. Fortes ; E. Suard ; K. S. Knight
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-02-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Manfredo Vieira, S., Hiltensperger, M., Kumar, V., Zegarra-Ruiz, D., Dehner, C., Khan, N., Costa, F. R. C., Tiniakou, E., Greiling, T., Ruff, W., Barbieri, A., Kriegel, C., Mehta, S. S., Knight, J. R., Jain, D., Goodman, A. L., Kriegel, M. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Immunology, Medicine, DiseasesPublished by: -
4Charles E. Flower; Douglas J. Lynch; Kathleen S. Knight; Miquel A. Gonzalez-Meler
MDPI Publishing
Published 2018Staff ViewPublication Date: 2018-05-29Publisher: MDPI PublishingElectronic ISSN: 1999-4907Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionPublished by: -
5Jing M. Ren, Jimmy Lawrence, Abigail S. Knight, Allison Abdilla, Raghida Bou Zerdan, Adam E. Levi, Bernd Oschmann, Will R. Gutekunst, Sang-Ho Lee, Youli Li, Alaina J. McGrath, Christopher M. Bates, Greg G. Qiao and Craig J. Hawker
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-01-31Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
6Charles E. Flower; Jeremie B. Fant; Sean Hoban; Kathleen S. Knight; Laura Steger; Elijah Aubihl; Miquel A. Gonzalez-Meler; Stephen Forry; Andrea Hille; Alejandro A. Royo
MDPI Publishing
Published 2018Staff ViewPublication Date: 2018-04-14Publisher: MDPI PublishingElectronic ISSN: 1999-4907Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionPublished by: -
7Staff View
Publication Date: 2018-04-18Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Semiconductors I: bulkPublished by: -
8P. A. Perez-Mancera ; A. G. Rust ; L. van der Weyden ; G. Kristiansen ; A. Li ; A. L. Sarver ; K. A. Silverstein ; R. Grutzmann ; D. Aust ; P. Rummele ; T. Knosel ; C. Herd ; D. L. Stemple ; R. Kettleborough ; J. A. Brosnan ; R. Morgan ; S. Knight ; J. Yu ; S. Stegeman ; L. S. Collier ; J. J. ten Hoeve ; J. de Ridder ; A. P. Klein ; M. Goggins ; R. H. Hruban ; D. K. Chang ; A. V. Biankin ; S. M. Grimmond ; L. F. Wessels ; S. A. Wood ; C. A. Iacobuzio-Donahue ; C. Pilarsky ; D. A. Largaespada ; D. J. Adams ; D. A. Tuveson
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-16Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Anoikis/genetics ; Carcinoma, Pancreatic Ductal/*enzymology/genetics/pathology ; Cell Line, Tumor ; Disease Models, Animal ; Endopeptidases ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Inbred C57BL ; Pancreatic Neoplasms/*enzymology/genetics/pathology ; U937 Cells ; Ubiquitin Thiolesterase/*genetics/*metabolismPublished by: -
9Dobenecker, M.-W., Park, J. S., Marcello, J., McCabe, M. T., Gregory, R., Knight, S. D., Rioja, I., Bassil, A. K., Prinjha, R. K., Tarakhovsky, A.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-04-03Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: AutoimmunityPublished by: -
10Staff View
Publication Date: 2018-08-03Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Pediatric Hematology, Plenary Papers, Red Cells, Iron, and ErythropoiesisPublished by: -
11Staff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
12Zavialov, A. V. ; Kersley, J. ; Korpela, T. ; Zav’yalov, V. P. ; MacIntyre, S. ; Knight, S. D.
Oxford, UK : Blackwell Science Ltd.
Published 2002Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: The F1 antigen of Yersinia pestis belongs to a class of non-pilus adhesins assembled via a classical chaperone–usher pathway. Such pathways consist of PapD-like chaperones that bind subunits and pilot them to the outer membrane usher, where they are assembled into surface structures. In a recombinant Escherichia coli model system, chaperone–subunit (Caf1M:Caf1n) complexes accumulate in the periplasm. Three inde-pendent methods showed that these complexes are rod- or coil-shaped linear arrays of Caf1 subunits capped at one end by a single copy of Caf1M chaperone. Deletion and point mutagenesis identified an N-terminal donor strand region of Caf1 that was essential for polymerization in vitro, in the periplasm and at the cell surface, but not for chaperone–subunit interaction. Partial protease digestion of periplasmic complexes revealed that this region becomes buried upon formation of Caf1:Caf1 contacts. These results show that, despite the capsule-like appearance of F1 antigen, the basic structure is assembled as a linear array of subunits held together by intersubunit donor strand complementation. This example shows that strikingly different architectures can be achieved by the same general principle of donor strand complementation and suggests that a similar basic polymer organization will be shared by all surface structures assembled by classical chaperone–usher pathways.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1752-1688Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Architecture, Civil Engineering, SurveyingGeographyNotes: : Longitudinal stone toe is one of the most reliable and economically attractive approaches for stabilizing eroding banks in incised channels. However, aquatic habitat provided by stone toe is inferior to that provided by spur dikes. In order to test a design that combined features of stone toe and spurs, eleven stone spurs were placed perpendicular to 170 m of existing stone toe in Goodwin Creek, Mississippi, and willow posts were planted in the sandbar on the opposite bank. Response was evaluated by monitoring fish and habitats in the treated reach and an adjacent comparison reach (willow post planting and standard toe without spurs) for four years. Furthermore, physical habitats within the treated reach were compared with seven reaches protected with standard toe on a single date three years after construction. Overall results indicated that spur addition resulted in modest increases in baseflow stony bankline, water width and pool habitat availability, but had only local effects on depth. These relatively small changes in physical habitat were exaggerated seasonally by beaver dams that appeared during periods of prolonged low flow in late Summer and Autumn. Physical changes were accompanied by shifts in fish species composition away from a run-dwelling assemblage dominated by large numbers of cyprinids and immature centrarchids toward an assemblage containing fewer and larger centrarchids. Biological responses were at least partially due to the effects of temporary beaver dams.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0025-8385Topics: Linguistics and Literary StudiesNotes: REVIEWSURL: -
15Staff View
ISSN: 0025-8385Topics: Linguistics and Literary StudiesURL: -
16Staff View
ISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Complex food proteins and enteric flora may act as antigenic stimuli in Crohn’s disease. This study assessed the prevalence and magnitude of lymphocyte priming to these antigens in Crohn’s disease.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:A total of 31 Crohn’s disease patients (median age 42 years, range 25–72 years) and 22 healthy controls (median 29 years, 23–43 years) were studied. Peripheral blood lymphocytes were collected and incubated with antigens in hanging drop culture for 4 days. The antigens tested were cow’s milk, cereals, cabbage group, citrus group, peanut group, Saccharomyces (yeast), Bacteroides, E. coli and Klebsiella. On the 4th day 3H-thymidine incorporation was measured after a 4-h pulse. Responses to antigens were considered positive if mean proliferative values were above the 99% confidence interval for background proliferation.〈section xml:id="abs1-3"〉〈title type="main"〉Results:The mean background and mitogen-stimulated proliferation did not differ between patients and controls. The mean proliferation to antigens was not above background in controls, but in Crohn’s patients proliferative responses to all food and bacterial antigens were significantly higher than background values. Twenty-three out of 31 Crohn’s patients and five out of 22 controls (P=0.0003) responded to one or more antigens. Sixteen Crohn’s patients and two controls responded to four or more antigens (P=0.001, Fisher’s exact test).〈section xml:id="abs1-4"〉〈title type="main"〉Conclusion:The reactivity of peripheral lymphocytes to food, yeast and bacterial antigens, especially multiple antigens, is common in Crohn’s disease. These sensitized lymphocytes may contribute to the inflammatory process.Type of Medium: Electronic ResourceURL: -
17Van Den Bogaerde, J. ; Cahill, J. ; Emmanuel, A. V. ; Vaizey, C. J. ; Talbot, I. C. ; Knight, S. C. ; Kamm, M. A.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background : Food antigens may contribute to gut inflammation in Crohn's disease.Aim : To assess in vivo sensitization to food antigens, ascertain whether sensitivity is gut specific, assess food sensitization in vitro, and correlate in vivo changes with histological and blood changes.Methods : Skin testing and rectal exposure to six food antigens (cereal, cabbage, citrus, milk, yeast and peanut) and control saline were assessed double-blind by immediate and 3.5-h laser Doppler blood flowmetry, and rectal biopsies were taken. Peripheral blood lymphocyte proliferation was measured in response to the same antigens.Results : Ten patients with Crohn's disease and 10 healthy controls were studied. Blood flow increased in 24 of 60 antigen sites in Crohn's disease patients and six of 60 antigen sites in controls (P 〈 0.0001) after 3.5 h. The Crohn's disease group demonstrated higher rectal blood flow than controls in response to all food antigens, and this was significantly different for the responses to yeast (P = 0.036) and citrus fruits (P = 0.038). Lymphocyte proliferation occurred in 32 of 60 tests in Crohn's disease patients and eight of 60 tests in controls (P 〈 0.0001). There were no skin responses. Submucosal oedema corresponded to increased mucosal flow.Conclusions : Crohn's disease patients demonstrate in vivo and in vitro sensitization to food antigens, which is gut specific. Mucosal flowmetry allows the identification of sensitization to gut antigens.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Early work on the fermentation of D-xylose-1-14C by the resting cells of Fusarium lini Bolley suggested a dissimilation similar to that in Lactobacillus pentosus1; namely, the conversion of the D-xylose to equimolar quantities of carbon dioxide, ethanol and acetic acid presumably following a split ...Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The fungi were grown on tomato juice-agar slants in Roux bottles, and after incubation at 25 C. for 3-10 days (depending on the growth-rate of a particular fungus) the spores were collected by adding water to the bottle and scraping the surface of the mycelium with a flattened metal rod. This ...Type of Medium: Electronic ResourceURL: -
20Cartwright, R. ; Stefoski, D. ; Caldarelli, D. ; Kravitz, H. ; Knight, S. ; Lloyd, S. ; Samelson, C.
Amsterdam : ElsevierStaff ViewISSN: 0005-7967Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: