Search Results - (Author, Cooperation:S. Knight)

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  1. 1
    Staff View
    Publication Date:
    2018-01-18
    Publisher:
    American Chemical Society (ACS)
    Print ISSN:
    0002-7863
    Electronic ISSN:
    1520-5126
    Topics:
    Chemistry and Pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    A. D. Fortes ; E. Suard ; K. S. Knight
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-02-12
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-03-09
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Immunology, Medicine, Diseases
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-05-29
    Publisher:
    MDPI Publishing
    Electronic ISSN:
    1999-4907
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Latest Papers from Table of Contents or Articles in Press
  6. 6
  7. 7
    A. Mock, R. Korlacki, S. Knight, and M. Schubert
    American Physical Society (APS)
    Published 2018
    Staff View
    Publication Date:
    2018-04-18
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Semiconductors I: bulk
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2012-06-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Anoikis/genetics ; Carcinoma, Pancreatic Ductal/*enzymology/genetics/pathology ; Cell Line, Tumor ; Disease Models, Animal ; Endopeptidases ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Inbred C57BL ; Pancreatic Neoplasms/*enzymology/genetics/pathology ; U937 Cells ; Ubiquitin Thiolesterase/*genetics/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2018-04-03
    Publisher:
    Rockefeller University Press
    Print ISSN:
    0022-1007
    Electronic ISSN:
    1540-9538
    Topics:
    Medicine
    Keywords:
    Autoimmunity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  10. 10
  11. 11
    Knight, S. G.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1966
    Staff View
    ISSN:
    1749-6632
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Natural Sciences in General
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Zavialov, A. V. ; Kersley, J. ; Korpela, T. ; Zav’yalov, V. P. ; MacIntyre, S. ; Knight, S. D.

    Oxford, UK : Blackwell Science Ltd.
    Published 2002
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The F1 antigen of Yersinia pestis belongs to a class of non-pilus adhesins assembled via a classical chaperone–usher pathway. Such pathways consist of PapD-like chaperones that bind subunits and pilot them to the outer membrane usher, where they are assembled into surface structures. In a recombinant Escherichia coli model system, chaperone–subunit (Caf1M:Caf1n) complexes accumulate in the periplasm. Three inde-pendent methods showed that these complexes are rod- or coil-shaped linear arrays of Caf1 subunits capped at one end by a single copy of Caf1M chaperone. Deletion and point mutagenesis identified an N-terminal donor strand region of Caf1 that was essential for polymerization in vitro, in the periplasm and at the cell surface, but not for chaperone–subunit interaction. Partial protease digestion of periplasmic complexes revealed that this region becomes buried upon formation of Caf1:Caf1 contacts. These results show that, despite the capsule-like appearance of F1 antigen, the basic structure is assembled as a linear array of subunits held together by intersubunit donor strand complementation. This example shows that strikingly different architectures can be achieved by the same general principle of donor strand complementation and suggests that a similar basic polymer organization will be shared by all surface structures assembled by classical chaperone–usher pathways.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  13. 13
    Shields, F D. ; Knight, S. S. ; Cooper, C. M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1998
    Staff View
    ISSN:
    1752-1688
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Architecture, Civil Engineering, Surveying
    Geography
    Notes:
    : Longitudinal stone toe is one of the most reliable and economically attractive approaches for stabilizing eroding banks in incised channels. However, aquatic habitat provided by stone toe is inferior to that provided by spur dikes. In order to test a design that combined features of stone toe and spurs, eleven stone spurs were placed perpendicular to 170 m of existing stone toe in Goodwin Creek, Mississippi, and willow posts were planted in the sandbar on the opposite bank. Response was evaluated by monitoring fish and habitats in the treated reach and an adjacent comparison reach (willow post planting and standard toe without spurs) for four years. Furthermore, physical habitats within the treated reach were compared with seven reaches protected with standard toe on a single date three years after construction. Overall results indicated that spur addition resulted in modest increases in baseflow stony bankline, water width and pool habitat availability, but had only local effects on depth. These relatively small changes in physical habitat were exaggerated seasonally by beaver dams that appeared during periods of prolonged low flow in late Summer and Autumn. Physical changes were accompanied by shifts in fish species composition away from a run-dwelling assemblage dominated by large numbers of cyprinids and immature centrarchids toward an assemblage containing fewer and larger centrarchids. Biological responses were at least partially due to the effects of temporary beaver dams.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
  15. 15
    KNIGHT, S. T.

    Oxford : Periodicals Archive Online (PAO)
    Published 1969
    Articles: DFG German National Licenses
  16. 16
    Van Den Bogaerde, J. ; Kamm, M. A. ; Knight, S. C.

    Oxford UK : Blackwell Science Ltd
    Published 2001
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Complex food proteins and enteric flora may act as antigenic stimuli in Crohn’s disease. This study assessed the prevalence and magnitude of lymphocyte priming to these antigens in Crohn’s disease.〈section xml:id="abs1-2"〉〈title type="main"〉Methods:A total of 31 Crohn’s disease patients (median age 42 years, range 25–72 years) and 22 healthy controls (median 29 years, 23–43 years) were studied. Peripheral blood lymphocytes were collected and incubated with antigens in hanging drop culture for 4 days. The antigens tested were cow’s milk, cereals, cabbage group, citrus group, peanut group, Saccharomyces (yeast), Bacteroides, E. coli and Klebsiella. On the 4th day 3H-thymidine incorporation was measured after a 4-h pulse. Responses to antigens were considered positive if mean proliferative values were above the 99% confidence interval for background proliferation.〈section xml:id="abs1-3"〉〈title type="main"〉Results:The mean background and mitogen-stimulated proliferation did not differ between patients and controls. The mean proliferation to antigens was not above background in controls, but in Crohn’s patients proliferative responses to all food and bacterial antigens were significantly higher than background values. Twenty-three out of 31 Crohn’s patients and five out of 22 controls (P=0.0003) responded to one or more antigens. Sixteen Crohn’s patients and two controls responded to four or more antigens (P=0.001, Fisher’s exact test).〈section xml:id="abs1-4"〉〈title type="main"〉Conclusion:The reactivity of peripheral lymphocytes to food, yeast and bacterial antigens, especially multiple antigens, is common in Crohn’s disease. These sensitized lymphocytes may contribute to the inflammatory process.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Van Den Bogaerde, J. ; Cahill, J. ; Emmanuel, A. V. ; Vaizey, C. J. ; Talbot, I. C. ; Knight, S. C. ; Kamm, M. A.

    Oxford, UK : Blackwell Science Ltd
    Published 2002
    Staff View
    ISSN:
    1365-2036
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background : Food antigens may contribute to gut inflammation in Crohn's disease.Aim : To assess in vivo sensitization to food antigens, ascertain whether sensitivity is gut specific, assess food sensitization in vitro, and correlate in vivo changes with histological and blood changes.Methods : Skin testing and rectal exposure to six food antigens (cereal, cabbage, citrus, milk, yeast and peanut) and control saline were assessed double-blind by immediate and 3.5-h laser Doppler blood flowmetry, and rectal biopsies were taken. Peripheral blood lymphocyte proliferation was measured in response to the same antigens.Results : Ten patients with Crohn's disease and 10 healthy controls were studied. Blood flow increased in 24 of 60 antigen sites in Crohn's disease patients and six of 60 antigen sites in controls (P 〈 0.0001) after 3.5 h. The Crohn's disease group demonstrated higher rectal blood flow than controls in response to all food antigens, and this was significantly different for the responses to yeast (P = 0.036) and citrus fruits (P = 0.038). Lymphocyte proliferation occurred in 32 of 60 tests in Crohn's disease patients and eight of 60 tests in controls (P 〈 0.0001). There were no skin responses. Submucosal oedema corresponded to increased mucosal flow.Conclusions : Crohn's disease patients demonstrate in vivo and in vitro sensitization to food antigens, which is gut specific. Mucosal flowmetry allows the identification of sensitization to gut antigens.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    CHIANG, CHING ; KNIGHT, S. G.

    [s.l.] : Nature Publishing Group
    Published 1960
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Early work on the fermentation of D-xylose-1-14C by the resting cells of Fusarium lini Bolley suggested a dissimilation similar to that in Lactobacillus pentosus1; namely, the conversion of the D-xylose to equimolar quantities of carbon dioxide, ethanol and acetic acid presumably following a split ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    GEHRIG, R. F. ; KNIGHT, S. G.

    [s.l.] : Nature Publishing Group
    Published 1961
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The fungi were grown on tomato juice-agar slants in Roux bottles, and after incubation at 25 C. for 3-10 days (depending on the growth-rate of a particular fungus) the spores were collected by adding water to the bottle and scraping the surface of the mycelium with a flattened metal rod. This ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0005-7967
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses