Search Results - (Author, Cooperation:S. Kano)
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1Latest Papers from Table of Contents or Articles in PressM. Niwa ; H. Jaaro-Peled ; S. Tankou ; S. Seshadri ; T. Hikida ; Y. Matsumoto ; N. G. Cascella ; S. Kano ; N. Ozaki ; T. Nabeshima ; A. Sawa
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-01-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adolescent ; *Adolescent Behavior ; *Adolescent Development ; Affective Disorders, Psychotic/genetics/*metabolism ; Animals ; Disease Models, Animal ; Dopaminergic Neurons/*metabolism ; *Epigenesis, Genetic ; Glucocorticoids/*metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Tissue Proteins/genetics/metabolism ; Stress, Psychological/genetics/*metabolismPublished by: -
2Articles: DFG German National LicensesOhashi, M. ; Kondo, T. ; Ito, R. ; Fukatsu, S. ; Shiraki, Y. ; Kumata, K. ; Kano, S. S.
[S.l.] : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The quadratic nonlinear optical coefficient in the AlGaAs system has been systematically measured as a function of the alloy composition at the fundamental wavelength of 1.064 μm by the method of reflected harmonics. The harmonic waves from the thin-film samples are analyzed considering various interferences including multiple reflections. The experimental results show a reduction of the magnitude of the second-harmonic coefficient with increasing Al content in the AlGaAs system. This tendency is consistent with Miller's rule.Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesKano, S. ; Langford, S. C. ; Dickinson, J. T.
[S.l.] : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We present unambiguous evidence for direct, nonthermal laser desorption of molecular ions from the surface of an ionic wide band gap material, single crystal MgO. Using time resolved mass spectroscopy, we measure positive ions emitted during pulsed excimer laser irradiation at 248 nm. Species observed (besides singly and doubly charged Mg) include: Mg2+, MgO+, MgO2+ , Mg2O+ and (MgO)2+. The kinetic energies determined from time of flight measurements are species dependent, nearly independent of fluence, and range from 5 to 9 eV. The ion intensities display strongly nonlinear fluence dependencies, proportional to the fluence to the nth power, where n ranges from 3 to 4. These kinetic energies and fluence dependences support a defect mediated photoelectronic desorption mechanism. Emission is attributed to molecular ion precursors adsorbed at special sites associated with surface electron traps. Emission occurs when the electron trap is photoionized via the sequential absorption of 3–4 photons. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesHase, Y. ; Kumata, K. ; Kano, S. S. ; Ohashi, M. ; Kondo, T. ; Ito, R. ; Shiraki, Y.
Woodbury, NY : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: A new scheme for characterizing the quadratic optical nonlinearity of thin films grown on opaque substrates is proposed and demonstrated. This involved the measurement, as a function of the film thickness, of second-harmonic waves reflected from a film surface. The d36 coefficient of a ZnSe-on-GaAs film is estimated by this method to be 33±7 pm/V at the fundamental wavelength of 1.06 μm, which agrees reasonably well with the known value for the bulk crystal.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesKashitani, M. ; Fujino, T. ; Fukuyama, K. ; Kubota, J. ; Kondo, J. N. ; Wada, A. ; Domen, K. ; Hirose, C. ; Wakabayashi, F. ; Ishida, M. ; Goto, F. ; Kano, S. S.
College Park, Md. : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Transient spectra following the v=1←0 excitation of the OH stretching mode of Brønsted acidic hydroxyl groups in normal and deuterated mordenite zeolites have been measured by a two-color picosecond pump–probe technique. When the OH and OD stretching bands were excited by resonant IR pulses, transient bleaching of the fundamental band (v=1←0) and the transient hot band (v=2←1) absorption signal were observed. For the OH and OD groups free of adsorbates, the spectral widths of the pump-induced signals were broadened by ∼4 cm−1 due to pure dephasing from the convoluted width of the pump and probe IR pulses. When the OH and OD groups were adsorbed by a Xe atom, the frequencies of the ν(OH) and ν(OD) bands shifted to lower frequency and at the same time the widths of both the transient bleaching and the transient hot band absorption were much broader than those of the isolated hydroxyl groups by the factor of more than three. Actually, the widths of the transient signals were about the same as those of the linear absorption signals. An adiabatic approximation has been employed to interpret the observed broadening/shift of the IR bands by making use of the results of DFT (density functional theory) calculations performed on a model cluster consisting of a Xe atom and an H3Si–(OH)–AlH3 substrate. The result agreed well with the observed spectral features. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesFujino, T. ; Furuki, M. ; Kashitani, M. ; Onda, K. ; Kubota, J. ; Kondo, J. N. ; Wada, A. ; Domen, K. ; Hirose, C. ; Wakabayashi, F. ; Ishida, M. ; Goto, F. ; Kano, S. S.
College Park, Md. : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: By means of tunable infrared pump–probe experiment, vibrational relaxation rates (v=1→0) of OH stretching mode of Brønsted acidic hydroxyl groups in a mordenite zeolite, which were interacting with noble gases (He, Ar, Kr, or Xe), were measured. The population lifetime, T1, decreased with the increase of the interaction with noble gases, e.g., 170 ps and 58 ps for isolated hydroxyl groups and ones interacting with Xe, respectively. Using a simple linear chain model, the mechanism for the enhancement of the relaxation rate was studied. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesOkazaki, H. ; Kakurai, M. ; Hirata, D. ; Sato, H. ; Kamimura, T. ; Onai, N. ; Matsushima, K. ; Nakagawa, H. ; Kano, S. ; Minota, S.
Oxford, UK : Blackwell Science, Ltd
Published 2002Staff ViewISSN: 1365-2222Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background Th2 and Th1 cells have been suggested to express CCR3/CCR4 and CCR5/CXCR3, respectively.Objective We examined CCR3, CCR4, CCR5 and CXCR3 expression and cytokine production in peripheral blood CD4+ T cells from patients with atopic dermatitis (AD), which has been postulated to be a Th2-type cell-mediated disease, and then analysed the possible correlation between these values and the levels of several clinical parameters.Methods Intracellular cytokine production and chemokine receptor expression in peripheral blood CD4+ T cells from 40 AD patients and 20 sex- and age-matched healthy control subjects were studied by flow cytometry.Results The frequencies of IL-4- and IL-13-producing CD4+ T cells from patients with AD were significantly higher than those from healthy control subjects (IL-4:3.9 ± 2.1% vs. 1.6 ± 0.7%, P = 0.0005, IL-13:4.0 ± 2.1% vs. 1.8 ± 0.8%, P = 0.0023), whereas the frequencies of IL-2- and IFN-γ-producing CD4+ T cells were significantly decreased in AD patients (IL-2:38.1 ± 10.3% vs. 51.3 ± 6.3%, P = 0.0003, IFN-γ: 9.9 ± 3.5% vs. 26.4 ± 4.6%, P 〈 0.0001). The percentage of CCR4+ cells in CD4+ CD45RO+ T cells in AD patients was significantly higher than that in healthy control subjects (24.4 ± 8.0% vs. 10.9 ± 2.3%, P 〈 0.0001) and was correlated positively with the total serum IgE, serum lactic dehydrogenase (LDH) level, eosinophil number, eruption score, and IL-4 and IL-13 secretion in CD4+ T cells, and inversely with IL-2 and IFN-γ secretion in CD4+ T cells. In contrast, CCR3 was not detected on circulating CD4+ T cells even in AD patients. On the other hand, the percentage of CCR5+ or CXCR3+ cells in CD4+ CD45RO+ T cells in AD patients was significantly decreased (CCR5:23.2 ± 7.0% vs. 28.4 ± 5.4%, P = 0.023, CXCR3:29.9 ± 11.4% vs. 38.5 ± 6.7%, P = 0.028) and was positively correlated with eruption score (P 〈 0.05). Multiple regression analyses showed that the percentage of CCR4 expression highly correlated with serum IgE, LDH, eosinophil number and eruption in AD patients.Conclusion CCR4+ cells might be involved in the aetiopathogenesis of AD.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0005-2760Keywords: (Rat liver) ; Diacylglycerol ; Phospholipid ; Triacylglycerol synthesisSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1043-4666Keywords: L-arginine ; cGMP ; interleukin 1 ; transforming growth factor-βSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesSeino, Y. ; Ikeda, U. ; Ikeda, M. ; Yamamoto, K. ; Misawa, Y. ; Hasegawa, T. ; Kano, S. ; Shimada, K.
Amsterdam : ElsevierStaff ViewISSN: 1043-4666Keywords: PCR ; atherosclerosis ; in situ hybridization ; interleukin 6Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0022-2313Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesNakajima, H. ; Yokoyama, N. ; Kano, S. ; Ueno, F. ; Fujita, M. ; Kurihara, Y. ; Iwata, S.
Amsterdam : ElsevierStaff ViewISSN: 0022-3115Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1437-160XKeywords: Human parvovirus B19 ; Juvenile rheumatoid arthritis ; Rheumatoid arthritis ; Refractory groupSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We investigated the prevalence of antihuman parvovirus B19 immunoglobulin G (IgG) antibody in 108 Japanese patients with rheumatoid arthritis (RA) and 11 patients with polyarticular juvenile rheumatoid arthritis (JRA). Seropositivity of anti-B19 was significantly higher in patients with refractory RA (57.6%, 38/66) compared with patients with remittent RA (19.0%, 8/42; P〉0.001) or age-matched controls (24.3%, 19/78; P〉0.001). Patients with refractory polyarticular JRA had a significantly higher frequency of anti-B19 seropositivity (71.4%, 5/7) than age-matched controls (8.3%, 5/60; P〉0.001), while none of the remittent group was positive for the antibody (0/4).Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1432-0649Keywords: 81.15 Gh ; 82 ; 42.60Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We have investigated the glow discharge plasma of SiH4−NH3 mixture by CARS. The decomposition rate of NH3 is linearly dependent on SiH4 partial pressure but that of SiH4 is not affected by the mixing ratio.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: