Search Results - (Author, Cooperation:S. Jacobs)
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1Latest Papers from Table of Contents or Articles in PressDegryse, S., Bornschein, S., de Bock, C. E., Leroy, E., Vanden Bempt, M., Demeyer, S., Jacobs, K., Geerdens, E., Gielen, O., Soulier, J., Harrison, C. J., Constantinescu, S. N., Cools, J.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-01-26Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid Neoplasia, Brief ReportsPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-03-06Publisher: Oxford University PressPrint ISSN: 0267-8357Electronic ISSN: 1464-3804Topics: BiologyMedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-08-10Publisher: MDPI PublishingElectronic ISSN: 1424-2818Topics: BiologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressE. Rignot ; S. Jacobs ; J. Mouginot ; B. Scheuchl
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-06-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Latest Papers from Table of Contents or Articles in PressA. Shepherd ; E. R. Ivins ; G. A ; V. R. Barletta ; M. J. Bentley ; S. Bettadpur ; K. H. Briggs ; D. H. Bromwich ; R. Forsberg ; N. Galin ; M. Horwath ; S. Jacobs ; I. Joughin ; M. A. King ; J. T. Lenaerts ; J. Li ; S. R. Ligtenberg ; A. Luckman ; S. B. Luthcke ; M. McMillan ; R. Meister ; G. Milne ; J. Mouginot ; A. Muir ; J. P. Nicolas ; J. Paden ; A. J. Payne ; H. Pritchard ; E. Rignot ; H. Rott ; L. S. Sorensen ; T. A. Scambos ; B. Scheuchl ; E. J. Schrama ; B. Smith ; A. V. Sundal ; J. H. van Angelen ; W. J. van de Berg ; M. R. van den Broeke ; D. G. Vaughan ; I. Velicogna ; J. Wahr ; P. L. Whitehouse ; D. J. Wingham ; D. Yi ; D. Young ; H. J. Zwally
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-12-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antarctic Regions ; *Climate Change ; Geographic Information Systems ; Greenland ; *Ice CoverPublished by: -
6Latest Papers from Table of Contents or Articles in PressS. Bissiere ; M. Zelikowsky ; R. Ponnusamy ; N. S. Jacobs ; H. T. Blair ; M. S. Fanselow
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-01-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Carbenoxolone/pharmacology ; Conditioning, Classical ; Connexins/antagonists & inhibitors/metabolism ; Electrical Synapses/drug effects/*physiology ; Extinction, Psychological ; *Fear ; Gene Expression/drug effects ; Genes, fos ; Hippocampus/*physiology ; *Learning ; Male ; Mefloquine/pharmacology ; *Memory ; Rats ; Rats, Long-Evans ; Theta RhythmPublished by: -
7Articles: DFG German National LicensesSoures, J. M. ; McCrory, R. L. ; Verdon, C. P. ; Babushkin, A. ; Bahr, R. E. ; Boehly, T. R. ; Boni, R. ; Bradley, D. K. ; Brown, D. L. ; Craxton, R. S. ; Delettrez, J. A. ; Donaldson, W. R. ; Epstein, R. ; Jaanimagi, P. A. ; Jacobs, S. D. ; Kearney, K. ; Keck, R. L. ; Kelly, J. H. ; Kessler, T. J. ; Kremens, R. L. ; Knauer, J. P. ; Kumpan, S. A. ; Letzring, S. A. ; Lonobile, D. J. ; Loucks, S. J.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: OMEGA, a 60-beam, 351 nm, Nd:glass laser with an on-target energy capability of more than 40 kJ, is a flexible facility that can be used for both direct- and indirect-drive targets and is designed to ultimately achieve irradiation uniformity of 1% on direct-drive capsules with shaped laser pulses (dynamic range (approximately-greater-than)400:1). The OMEGA program for the next five years includes plasma physics experiments to investigate laser–matter interaction physics at temperatures, densities, and scale lengths approaching those of direct-drive capsules designed for the 1.8 MJ National Ignition Facility (NIF); experiments to characterize and mitigate the deleterious effects of hydrodynamic instabilities; and implosion experiments with capsules that are hydrodynamically equivalent to high-gain, direct-drive capsules. Details are presented of the OMEGA direct-drive experimental program and initial data from direct-drive implosion experiments that have achieved the highest thermonuclear yield (1014 DT neutrons) and yield efficiency (1% of scientific breakeven) ever attained in laser-fusion experiments. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesTsai, M. L. ; Chen, S. H. ; Jacobs, S. D.
Woodbury, NY : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Poly(γ-benzyl L-glutamate), partially transesterified with 1-dodecanol, and polysiloxane were employed to fabricate a right- and left-handed optical element, respectively. The wavelength of selective reflection was tuned via physical blending or annealing at a proper temperature. An optical notch filter comprising elements with each handedness showed an optical density of 2.0 within the rejection band and 73 to 83% transmission outside the band, suggesting liquid crystalline polymers as promising materials for the construction of environmentally robust optical notch filters.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesMarshall, K. L. ; Schmid, A. W. ; Smith, D. J. ; Bevin, A. A. ; Guardalben, M. J. ; Jacobs, S. D.
[S.l.] : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: KDP, KD*P, and LiNbO3, three nonlinear optical materials that have been difficult to coat, are treated with polymeric surface layers. These layers hermetically seal the hygroscopic crystal surfaces. Their optical properties, thermal compatibility, high-power laser damage behavior, abrasive resistance, and suitability for overcoating with traditional, dielectric antireflection multilayers are reported.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesTachelet, W. ; Jacobs, S. ; Ndayikengurukiye, H. ; Geise, H. J. ; Grüner, J.
Woodbury, NY : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We report electroluminescence of electroluminescent devices fabricated from cis,trans- 2,5-dimethoxy-1,4 -bis[2-(3,4,5-trimethoxyphenyl)ethenyl]benzene blended in a polystyrene matrix as emission layer. This choice of materials avoids the inherently poor miscibility of polymers with other compounds and minimizes interactions between the host polymer and the electro-optically active guest, which can produce quenching sites. A blue light-emitting device with high internal quantum efficiency (∼1%) results.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesKepler, R. G. ; Beeson, P. M. ; Jacobs, S. J. ; Anderson, R. A. ; Sinclair, M. B. ; Valencia, V. S. ; Cahill, P. A.
Woodbury, NY : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We have measured the drift mobility of electrons and holes in thin, vapor-deposited films of tris(8-hydroxyquinolinolato-N1,O8) aluminum using a time of flight photoconductivity technique. The drift of mobility of both carriers is dispersive and strongly electric field and temperature dependent. At ambient temperature and an electric field of 4×105 V cm−1, the effective mobility of electrons and holes is 1.4×10−6 and 2×10−8 cm2 V−1 s−1, respectively, in a 400 nm thick sample. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The APACHE II sickness score was applied prospectively for one year in a general intensive care unit in Saudi Arabia. Two hundred and ten patients were studied, 66 of whom died in hospital. The mean APACHE II score of survivors was 11 (SD 7.1) and of non-survivors, 25.3 (SD 8.8). The mean Risk of Death was 13.3% (SD 13.1) for the survivors and 47.2% (SD 25.8) for non-survivors. The differences in APACHE score and Risk of Death between survivors and non-survivors are highly significant (p 〈 0.0005 for both). No patient survived who had a Risk of Death greater than 60% and none died with a Risk of Death less than 7%. The sensitivity of the APACHE II system in predictions of death can be improved if the scores on the day of admission and on the 3rd day are taken into account.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesJACOBS, S. ; PULLAN, P. T. ; POTTER, JULIA M. ; SHENFIELD, G. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1983Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Adrenocortical function was tested in 12 patients following a single lumbar extradural injection ofmethyl-prednisolone acetate (‘Depo-Medrol’) 80 mg as treatment for chronic sciatica. There was no absorption of the corticosteroid into the systemic circulation, but marked suppression of plasma Cortisol levels was documented for up to 3 weeks following the injection and the capacity of the adrenal cortex to secrete Cortisol in response to synthetic adrenocorticotrophin (ACTH) was diminished. These results suggest that the dose and frequency of extradural steroid administration should be kept to a minimum to prevent suppression of the hypothalamicjpituitaryladrenocortical axis and that patients thus treated should he considered candidates for steroid cover during surgery and other stressful procedures.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesARNOLD, A. ; TOVEY, J. ; MANGAT, P. ; PENNY, W. ; JACOBS, S.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A study was performed to assess the value of estimation of intracellular magnesium in peripheral blood cells (red and mononuclear blood cells) in critically ill patients as an index of tissue magnesium content. A magnesium loading test was used to diagnose magnesium depletion in 16 critically ill patients. Patients were divided into magnesium depleted and non-depleted groups according to their response to the loading test. Pre -infusion plasma and intracellular (blood cell) magnesium levels were measured. There were no significant differences between the magnesium depleted (mean plasma magnesium 0.81 mmol.l-1, red blood cell magnesium 2.34mmol.l-1, mononuclear blood cell magnesium 25.16mmol.kg-1 dry weight) and non-depleted groups (mean plasma magnesium 0.90mmol.l-1, red blood cell magnesium 2.18mmol.l-1, mononuclear blood cell magnesium 18.1 mmol.kg-1 dry weight). We conclude that the diagnosis of magnesium depletion cannot be excluded in the face of normal plasma, red blood cell or mononuclear blood cell concentrations of magnesium.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesLambropoulos, J. C. ; Jolly, M. R. ; Amsden, C. A. ; Gilman, S. E. ; Sinicropi, M. J. ; Diakomihalis, D. ; Jacobs, S. D.
[S.l.] : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A direct reading thermal comparator has been used to measure the thermal conductivity of dielectric thin-film coatings. In the past, the thermal comparator has been used extensively to measure the thermal conductivity of bulk solids, liquids, and gases. The technique has been extended to thin-film materials by making experimental improvements and by the application of an analytical heat flow model. Our technique also allows an estimation of the thermal resistance of the film/substrate interface which is shown to depend on the method of film deposition. The thermal conductivity of most thin films was found to be several orders of magnitude lower than that of the material in bulk form. This difference is attributed to structural disorder of materials deposited in thin-film form. The experimentation to date has primarily centered on optical coating materials. These coatings, used to enhance the optical properties of components such as lenses and mirrors, are damaged by thermal loads applied in high-power laser applications. It has been widely postulated that there may be a correlation between the thermal conductivity and the damage threshold of these materials.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesJacobs, S. ; Shortland, G. ; Warner, J. ; Dearden, A. ; Gataure, P. Singh ; Tarpey, J.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The Syracuse croup scoring system was validated in 165 children with croup who were admitted to an intensive therapy unit for assessment over a one year period. The unit served as a croup triage point for Cardiff and its environs. A score of 〉 5 was taken as an indication that a patient was at risk of upper airway obstruction and was used to support a triage decision by the junior hospital doctor to admit a patient to the intensive therapy unit. All patients with an initial score ≤ 5 were considered safe for transfer to a general paediatric ward and none of these required subsequent admission to intensive care. This score was then tested on a further 134 children with croup, in order to identify those patients who required specialised monitoring, observation or treatment in intensive care. A score of 〉 5 gave a specificity of 100% and a sensitivity of 80%. Croup scoring continued after admission on the general paediatric wards. Two patients who were originally admitted to the intensive therapy unit with a score 〉 5 improved within 6 h and were transferred to the general ward with a score ≤ 5. These children subsequently required readmission to the intensive therapy unit. Our tracheal intubation rate of 2% was low and may relate to the routine use of regular adrenaline nebulisation. We recommend this scoring system to other paediatric departments for initial triaging decisions and for documenting progress on the wards.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesJACOBS, S. ; ARNOLD, A. ; CLYBURN, P. A. ; WILLIS, B. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A computerised system of prediction of death using the Riyadh Intensive Care Program was applied retrospectively over a 17-month period to data collected prospectively on 1155 patients admitted to our intensive care unit. Variables which enable organ failure scores to be generated were recorded daily to make these predictions. Consultant medical opinion predicted that outcome was hopeless in 55% (115/209) of the patients who died. The predictive power of the computer demonstrated a sensitivity of 14.8% and a specificity of 99.8%. It is possible that the occurrence of three false predictions of death in the latter part of the series may have been related to a change in our antibiotic policy. We would be unhappy to recommend the general use of a computerised program for prediction of death without careful explanation of its significance and dangers.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesJacobs, S. ; Arnold, A. ; Clyburn, P.A. ; Willis, B.A.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: