Search Results - (Author, Cooperation:S. J. O'Brien)
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1C. A. Driscoll ; S. Luo ; D. MacDonald ; E. Dinerstein ; I. Chestin ; O. Pereladova ; S. J. O'Brien
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-13Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Asia, Central ; *Ecosystem ; Kazakhstan ; Population Dynamics ; *TigersPublished by: -
2G. Zhang ; C. Li ; Q. Li ; B. Li ; D. M. Larkin ; C. Lee ; J. F. Storz ; A. Antunes ; M. J. Greenwold ; R. W. Meredith ; A. Odeen ; J. Cui ; Q. Zhou ; L. Xu ; H. Pan ; Z. Wang ; L. Jin ; P. Zhang ; H. Hu ; W. Yang ; J. Hu ; J. Xiao ; Z. Yang ; Y. Liu ; Q. Xie ; H. Yu ; J. Lian ; P. Wen ; F. Zhang ; H. Li ; Y. Zeng ; Z. Xiong ; S. Liu ; L. Zhou ; Z. Huang ; N. An ; J. Wang ; Q. Zheng ; Y. Xiong ; G. Wang ; B. Wang ; Y. Fan ; R. R. da Fonseca ; A. Alfaro-Nunez ; M. Schubert ; L. Orlando ; T. Mourier ; J. T. Howard ; G. Ganapathy ; A. Pfenning ; O. Whitney ; M. V. Rivas ; E. Hara ; J. Smith ; M. Farre ; J. Narayan ; G. Slavov ; M. N. Romanov ; R. Borges ; J. P. Machado ; I. Khan ; M. S. Springer ; J. Gatesy ; F. G. Hoffmann ; J. C. Opazo ; O. Hastad ; R. H. Sawyer ; H. Kim ; K. W. Kim ; H. J. Kim ; S. Cho ; N. Li ; Y. Huang ; M. W. Bruford ; X. Zhan ; A. Dixon ; M. F. Bertelsen ; E. Derryberry ; W. Warren ; R. K. Wilson ; S. Li ; D. A. Ray ; R. E. Green ; S. J. O'Brien ; D. Griffin ; W. E. Johnson ; D. Haussler ; O. A. Ryder ; E. Willerslev ; G. R. Graves ; P. Alstrom ; J. Fjeldsa ; D. P. Mindell ; S. V. Edwards ; E. L. Braun ; C. Rahbek ; D. W. Burt ; P. Houde ; Y. Zhang ; H. Yang ; E. D. Jarvis ; M. T. Gilbert
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-12-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological ; Animals ; Biodiversity ; *Biological Evolution ; Birds/classification/*genetics/physiology ; Conserved Sequence ; Diet ; *Evolution, Molecular ; Female ; Flight, Animal ; Genes ; Genetic Variation ; *Genome ; Genomics ; Male ; Molecular Sequence Annotation ; Phylogeny ; Reproduction/genetics ; Selection, Genetic ; Sequence Analysis, DNA ; Synteny ; Vision, Ocular/genetics ; Vocalization, AnimalPublished by: -
3T. K. Oleksyk ; V. Brukhin ; S. J. O'Brien
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-14Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: DNA/*genetics ; *DNA Mutational Analysis ; Genome, Human/*genetics ; HumansPublished by: -
4C. B. Kaelin ; X. Xu ; L. Z. Hong ; V. A. David ; K. A. McGowan ; A. Schmidt-Kuntzel ; M. E. Roelke ; J. Pino ; J. Pontius ; G. M. Cooper ; H. Manuel ; W. F. Swanson ; L. Marker ; C. K. Harper ; A. van Dyk ; B. Yue ; J. C. Mullikin ; W. C. Warren ; E. Eizirik ; L. Kos ; S. J. O'Brien ; G. S. Barsh ; M. Menotti-Raymond
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-09-22Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Acinonyx/genetics/metabolism ; Alleles ; Aminopeptidases/chemistry/*genetics/metabolism ; Animals ; Cats/embryology/*genetics/growth & development/metabolism ; Endothelin-3/*genetics/metabolism ; Epistasis, Genetic ; Felidae/*genetics/growth & development/metabolism ; Gene Expression Regulation ; Gene Frequency ; Genetic Variation ; Hair/embryology/growth & development ; Hair Color/*genetics ; Hair Follicle/embryology ; Haplotypes ; Metalloproteases/chemistry/*genetics/metabolism ; Mice ; Mice, Transgenic ; Panthera/genetics/metabolism ; Phenotype ; Polymorphism, Single Nucleotide ; Skin/anatomy & histology/embryology/*metabolism ; Species SpecificityPublished by: -
5SACK, G. H. ; TALBOT, C. C. ; SEUANEZ, H. ; O'BRIEN, S. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1989Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We have assigned the human serum amyloid A (SAA) gene family to a 90 kb region on the short arm of human chromosome 11(11p) by hybridization of defined genomic fragments of human SAA genes to DNA from rodent-human somatic cell hybrids and to large DNA fragments separated by transverse alternating field gel electrophoresis. We have also characterized SAA probe hybridization patterns in human DNA cleaved with restriction endonucleases Hind III, Pst I, Bg/II, Taq I, and Xba I and found invariant patterns except for a two-allele restriction fragment length polymorphism (RFLP) with Hind III. These studies show that the SAA gene family comprises at least three members in the haploid human genome and will be useful in identifying variant patterns and establishing linkage between members of the SAA gene family and other markers on chromosome 11.Type of Medium: Electronic ResourceURL: -
6Baker, C. S. ; Palumbi, S. R. ; Lambertsen, R. H. ; Weinrich, M. T. ; Calambokidis, J. ; O'Brien, S. J.
[s.l.] : Nature Publishing Group
Published 1990Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsType of Medium: Electronic ResourceURL: -
7Wildt, D. E. ; Bush, M. ; Goodrowe, K. L. ; Packer, C. ; Pusey, A. E. ; Brown, J. L. ; Joslin, P. ; O'Brien, S. J.
[s.l.] : Nature Publishing Group
Published 1987Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The lion (Panthera leo) is an attractive candidate for studying the interrelationship of genetics and reproduction. Lions have been studied extensively for centuries, and their numbers in Africa are vast (estimated as high as 200,000)8. The demography and behaviour of the lions in the Serengeti ...Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary In the course of a systematic study of cytogenetics, morphology, and clinical follow-up of hydatidiform moles we encountered two unusual cases of partial hydatidiform moles each with a 92,XXXY karyotype. Previously reported cases of tetraploidy, of 92,XXXX or 92,XXXY karyotype, resulted from a failure of the first mitotic division of a normal zygote. This is to our knowledge the first report of tetraploidy with XXXY sex chromosomes. Study of chromosomal heteromorphisms, isozymes, and restriction fragment length polymorphisms reveal that both present cases resulted from a combination of a haploid ovum with three haploid sets of paternal chromosomes either by the mechanism of trispermy (involving three separate haploid spermatozoa) or through dispermy (involving one haploid and one diploid sperm). Both cases resembled closely partial moles in their morphology; one gave a highly typical clinical picture while the other was recognized at an early voluntary abortion. Partial moles are ordinarily triploids of nearly always diandric constitution that evince focal villous swelling with cistern formation and focal trophoblastic hyperplasia. The findings here presented point to an association of molar phenotype with an excess of paternal over maternal haploid sets.Type of Medium: Electronic ResourceURL: -
9Evermann, J. F. ; Heeney, J. L. ; Roelke, M. E. ; McKeirnan, A. J. ; O'Brien, S. J.
Springer
Published 1988Staff ViewISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary An epizootic of feline infectious peritonitis in a captive cheetah population during 1982–1983 served to focus attention on the susceptibility of the cheetah (Acinoyx jubatus) to infectious disease. Subsequent observations based upon seroepidemiological surveys and electron microscopy of fecal material verified that cheetahs were indeed capable of being infected by coronaviruses, which were antigenically related to coronaviruses affecting domestic cats, i.e. feline infectious peritonitis virus/feline enteric coronavirus. Coincident with the apparent increased susceptibility of the cheetah to infectious diseases, were observations that the cheetah was genetically unusual insofar as large amounts of enzyme-encoding loci were monomorphic, and that unrelated cheetahs were capable of accepting allogenic skin grafts. These data provided the basis for a hypothesis that the cheetah, through intensive inbreeding, had become more susceptible to viral infections as a result of genetic homogeneity.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1573-1367Keywords: function points ; metrics ; SSADM ; structured methodsSource: Springer Online Journal Archives 1860-2000Topics: Computer ScienceNotes: Abstract A set of explicit counting rules for the use of function point analysis in SSADM v4 is presented, motivated by the need for an unambiguous, objective, and inexpensive measure of system size during the development process. Unadjusted MKII function points can be derived from the requirements specification (RS) phase of SSADM; it is argued that the ‘complexity adjustment’ factor of the standard function point method can be safely omitted. A prescriptive approach is taken, resulting in a repeatable and objective counting technique that may be automated. The application of the counting rules to other SSADM phases is considered. It is concluded that application to requirements analysis (RA) is possible but reduces the objectivity of the proposed method; application to logical system specification (LS) requires only monor extensions to the counting rules; and that the project-specific nature of physical design (PD) makes it unsuitable for application of such a general, prescriptive technique. There are no results of application or validation of the technique. The method can operate satisfactorily from existing project documentation and may be embedded in tools which generate such documentation. It satisfies the need for an xplicit set of objective counting rules for MkII function points for the widely used SSADM environment.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0148-7280Keywords: maturation of oocytes ; chromosomes ; IVF ; Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyNotes: The time course and conditions necessary for oocyte maturation and subsequent fertilization in vitro were studied in the domestic cat. Darkly pigmented oocytes surrounded by cumulus cells and a tight corona radiata were collected from ovaries removed at ovariohysterectomy. After culture in Eagle's minimum essential medium, oocytes were evaluated for nuclear maturation by analyzing chromosomal spreads. Oocytes achieved metaphase II after intervals of 40-48 hr of in vitro incubation. The incidence of maturation was enhanced (P〈0.05) when oocytes were recovered from inactive (54%) or follicular (56%) stage donors compared to those recovered from luteal phase (29%) or pregnant (35%) cats. The proportion of oocytes successfully maturing in vitro in medium containing no hormone supplementation (37%) was less (P〈0.01) than counterparts cultured in follicle-stimulating hormone (FSH) only (48%) or FSH and luteinizing hormone (LH) (54%). The efficiency of maturation was not influenced (P 〉0.05) by either maintenance/transport temperature (4°C vs. 22°C) or delaying recovery of oocytes from antral follicles (2-8 hr vs. 24-32 hr). Approximately 36% of the in vitro matured oocytes cocultured with spermatozoa demonstrated evidence of fertilization; however, there appeared to be a critical development period for maximizing the incidence of fertilization. These results demonstrate that domestic cat antral oocytes are capable of maturing in vitro, and maturation is influenced by the reproductive status of the donor and the presence of gonadotropins in the culture medium. These oocytes are capable of forming embryos and developing to at least the 16-cell stage in vitro.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: