Search Results - (Author, Cooperation:S. J. Gross)
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1Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2015-07-17Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Female ; Humans ; *Incidental Findings ; Maternal Welfare/*statistics & numerical data ; Pregnancy ; Pregnancy Complications/*diagnosis ; Prenatal Diagnosis/*utilizationPublished by: -
2Articles: DFG German National LicensesGROSS, S. J. ; SOARES, J. R. ; WONG, S-L. R. ; SCHUSTER, R. E.
[s.l.] : Nature Publishing Group
Published 1974Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A standard antibody-binding curve was obtained as follows: 4.5 ng (5,000 c.p.m.) of 3H-D8-THC (specific activity 465 mCimMol?1more than 98 %pure,New England Nuclear Corp.) was incubated for 2 h at 4 C with increasing dilutions of anti-serum (0.3 ml). The latter were made up with phosphate-buffered ...Type of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesGross, S. J. ; Tharapel, Avirachan T. ; Phillips, Owen P. ; Shulman, L. P. ; Pivnick, Enikö K. ; Park, V. M.
Springer
Published 1996Staff ViewISSN: 1432-1203Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract We report a patient with mosaicism for two different Robertsonian translocations, both involving chromosome 21. She carries an unbalanced cell line with an i(21q) and a balanced cell line with a rob(21q22q). She is phenotypically normal but has two children who inherited the i(21q) and have Down syndrome. We demonstrate that both abnormal chromosomes are dicentric and that the proband’s 21/21 rearrangement is an isochromosome formed from a maternally derived chromosome 21. We propose a model in which the i(21q) is the progenitor rearrangement in the proband, which subsequently participated in a nonreciprocal rearrangement characteristic of a jumping translocation. In addition, we review other cases of constitutional mosaicism involving jumping translocations.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1572-9702Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The efficacy of ivermectin, released intraruminally from a 28-day-delivery device was evaluated in two titration studies against induced infestations of adultRhipicephalus appendiculatus, R. evertsi andHyalomma truncatum on cattle. Cattle were given a sufficient number of devices to release ivermectin at approximately 20, 40, 60 or 80 μg kg−1 day−1 at a steady-state rate 7–28 days after administration. Tick mortality was recorded, engorged female ticks were weighed and individually incubated, and reproductive data were recorded to determine a reproductive index for the species at various dose levels. Mortality of male and female ticks compared to that of controls was directly related to the daily dose of ivermectin, as was the number of ticks not engorging. Ticks fed on ivermectin-treated cattle had a smaller mass when engorged and laid smaller egg-masses, both absolutely and as a proportion of engorged mass. The index of reproduction ofR. appendiculatus was reduced by more than 99.9% at 20 μg kg−1 day−1, and the reproductive indices ofR. evertsi andH. truncatum were reduced by more than 99.9% at dose rates of 40 μg kg−1 day−1 and above. Practical implications of the application of sustained-release ivermectin for the control of multihost ticks and tick-borne diseases are discussed.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesCruz, J. B. ; Benitez-Usher, C. ; Cramer, L. G. ; Gross, S. J. ; Kohn, A. B.
Springer
Published 1993Staff ViewISSN: 1432-1955Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract The efficacy of abamectin 1%, when injected subcutancously in cattle at a dose of 200 μg/kg body weight, against the larval stages (grubs) of the flyDermatobia hominis was evaluated in two trials in endemic areas of Brazil and Argentina. Eighteen Holstein x Brahman castrated males and 16 Brahman-cross with natural infestations were used. Larvae were counted by instar in situ on both sides of each animal before treatment, and were expressed, identified as to stage and classified as live or dead 10 days after treatment. Further larval counts were made periodically until day 79 to evaluate the degree of reinfestation and the stage of larval development. Reinfestation was first detected in the abamectin-treated cattle on day 44. Live larvae were found on 6–8 (Argentina) and on all (Brazil) controls at each posttreatment examination. The difference in numbers of live larvae between treatment groups was statistically significant (P〈0.05) at all post-treatment examinations. These data show that abamectin at a dose of 200 μg/kg body weight is highly effective in the treatment and control of established parasitic stages ofD. hominis in cattle. No adverse reactions were observed in any of the treated animals.Type of Medium: Electronic ResourceURL: