Search Results - (Author, Cooperation:S. Huber)
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1Doyard, M., Bacrot, S., Huber, C., Di Rocco, M., Goldenberg, A., Aglan, M. S., Brunelle, P., Temtamy, S., Michot, C., Otaify, G. A., Haudry, C., Castanet, M., Leroux, J., Bonnefont, J.-P., Munnich, A., Baujat, G., Lapunzina, P., Monnot, S., Ruiz-Perez, V. L., Cormier-Daire, V.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-03-23Publisher: BMJ Publishing GroupPrint ISSN: 0022-2593Electronic ISSN: 1468-6244Topics: MedicinePublished by: -
2N. Gagliani ; M. C. Amezcua Vesely ; A. Iseppon ; L. Brockmann ; H. Xu ; N. W. Palm ; M. R. de Zoete ; P. Licona-Limon ; R. S. Paiva ; T. Ching ; C. Weaver ; X. Zi ; X. Pan ; R. Fan ; L. X. Garmire ; M. J. Cotton ; Y. Drier ; B. Bernstein ; J. Geginat ; B. Stockinger ; E. Esplugues ; S. Huber ; R. A. Flavell
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Cell Transdifferentiation ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Helminthiasis/immunology ; Male ; Mice ; Nippostrongylus/immunology ; Staphylococcal Infections/immunology ; Staphylococcus aureus/immunology ; T-Lymphocytes, Regulatory/*cytology/*immunology ; Th17 Cells/*cytology/*immunologyPublished by: -
3E. Esplugues ; S. Huber ; N. Gagliani ; A. E. Hauser ; T. Town ; Y. Y. Wan ; W. O'Connor, Jr. ; A. Rongvaux ; N. Van Rooijen ; A. M. Haberman ; Y. Iwakura ; V. K. Kuchroo ; J. K. Kolls ; J. A. Bluestone ; K. C. Herold ; R. A. Flavell
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-07-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibodies/immunology/pharmacology ; Antigens, CD3/immunology ; CD4-Positive T-Lymphocytes/immunology/transplantation ; Cell Movement/drug effects ; Chemokine CCL20/immunology ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Gene Expression Profiling ; Gene Expression Regulation/immunology ; Influenza A virus/immunology ; Interleukin-17/immunology ; Intestine, Small/cytology/*immunology ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Transgenic ; Orthomyxoviridae Infections/immunology ; Receptors, CCR6/immunology ; Sepsis/immunology ; Staphylococcal Infections/immunology ; Th17 Cells/*immunologyPublished by: -
4S. Huber ; N. Gagliani ; L. A. Zenewicz ; F. J. Huber ; L. Bosurgi ; B. Hu ; M. Hedl ; W. Zhang ; W. O'Connor, Jr. ; A. J. Murphy ; D. M. Valenzuela ; G. D. Yancopoulos ; C. J. Booth ; J. H. Cho ; W. Ouyang ; C. Abraham ; R. A. Flavell
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-10-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Cell Transformation, Neoplastic ; Colitis/complications/metabolism/pathology ; Colon/metabolism/pathology ; Colonic Neoplasms/complications/metabolism/pathology ; Disease Models, Animal ; Down-Regulation ; Epithelial Cells/metabolism/pathology ; Genes, APC ; Inflammasomes/*metabolism ; Interleukin-18/metabolism ; Interleukins/deficiency/genetics/metabolism ; Intestines/*metabolism/*pathology ; Mice ; Mice, Knockout ; Receptors, Interleukin/deficiency/genetics/*metabolism ; Time Factors ; Weight LossPublished by: -
5A. Müller, A. Borovik, Jr., K. Huber, S. Schippers, D. V. Fursa, and I. Bray
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-02-27Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Atomic and molecular collisions and interactionsPublished by: -
6Mathies, F., Steffens, N., Kleinschmidt, D., Stuhlmann, F., Huber, F. J., Roy, U., Meyer, T., Luetgehetmann, M., von Petersdorff, M., Seiz, O., Herkel, J., Schramm, C., Flavell, R. A., Gagliani, N., Krebs, C., Panzer, U., Abdullah, Z., Strowig, T., Bedke, T., Huber, S.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-12-11Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
7Staff View
ISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The short-term and long-term effects of CO, enrichment on certain aspects of photosynthesis and leaf carbohydrate metabolism were studied with soybean [Glycine max (L.) Merr.] plants. In general, both long-term and short-term CO2 enrichment (300 ppm CO2 above ambient) of soybean plants resulted in increased rates of photosynthesis (per unit leaf area) and starch accumulation. Leaf sucrose concentrations were increased slightly, but the rate of assimilate export and activity of sucrose phosphate synthase (EC 2.4.1.14) were usually not increased. Plant N-status affected the response of vegetative soybean ‘Ransom’ plants to short-term CO, enrichment. When plants were N-stressed (2 mM NO3- supplied), CO2 enrichment resulted in increased rates of both starch accumulation and export. As N-supply was increased, partitioning of carbon into starch in CO2-enriched atmospheres increased at the expense of assimilate export. When plants were grown with high-N (20 mM NO3), the rate of assimilate export from CO2-enriched leaves was reduced below the rate observed with plants maintained at ambient CO2. The reduction in export rate was associated with decreased activities of sucrose phosphate synthase in leaf extracts. The activity of sucrose phosphate synthase in leaf extracts was closely associated with partitioning of carbon between starch and sucrose in leaves, and with the rate of assimilate export.Type of Medium: Electronic ResourceURL: -
8Kaiser, W. M. ; Weiner, H. ; Huber, S. C.
Copenhagen : Munksgaard International Publishers
Published 1999Staff ViewISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: In higher plants, cytosolic NAD(P)H-nitrate reductase (NR) is rapidly modulated by environmental conditions such as light, CO2, or oxygen availability. In leaves, NR is activated by photosynthesis, reaching an activation state of 60–80%. In the dark, or after stomatal closure, leaf NR is inactivated down to 20 or 40% of its maximum activity. In roots, hypoxia or anoxia activate NR, whereas high oxygen supply inactivates NR. Spinach leaf NR is inactivated by phosphorylation of serine 543 and subsequent Mg2+-dependent binding of 14-3-3 proteins at, or close to, this phosphorylation site. At least three different protein kinases (NR-PK) have been identified in spinach leaves that are able to phosphorylate NR on serine 543. Two of them show up as calmodulin-like domain protein kinases (CDPKs), and one as a SNF1-like protein kinase. Dephosphorylation of serine 543 is catalyzed by a Mg2+-dependent protein phosphatase and by a type 2A protein phosphatase (NR-PP), which is regulated by a trimer/dimer interconversion. The NR-PKs, NR-PPs, and 14-3-3s are present even in NR-depleted plant tissues. Artificial activation of NR in vivo is achieved by cellular acidification, by respiratory inhibitors, or by mannose feeding. As for anoxia, these treatments seem to act, at least in part, via cytosolic acidification, mediated by low cytosolic ATP levels. Activation is also achieved by ionophore-induced release of divalent cations from the cytosol. In addition, cytosolic AMP and phosphate esters seem to regulate NR-PK and NR-PP activities, thereby adapting NR activity within minutes to the changing environment.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0921-4534Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0038-1101Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0038-1101Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Electrical Engineering, Measurement and Control TechnologyPhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0022-4731Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Valta, P. ; Konopka, J. ; Berenguer, M. ; Bohnet, A. ; Jaenicke, J. ; Huber, S. ; Hartnack, C. ; Peilert, G. ; Stocker, H. ; Aichelin, J. ; Neise, L.W. ; Greiner, W.
Amsterdam : ElsevierStaff ViewISSN: 0375-9474Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
17Foster, J.A. ; Rich, C.B. ; Berglund, N. ; Huber, S. ; Mecham, R.P. ; Lange, G.
Amsterdam : ElsevierStaff ViewISSN: 0304-4165Keywords: Anti-proteolytic behaviorl ; Competitive inhibition ; Lathyrogen ; Tropoelastin ; α-Aminocetonitrile ; β-AminopropionnitrileSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 0045-6039Keywords: CpG dinucleotide distribution ; DNA methylation ; vertebrate genesSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
19Main, E. L. ; Pharr, D. M. ; Huber, S. C. ; Moreland, D. E.
Oxford, UK : Blackwell Publishing Ltd
Published 1983Staff ViewISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The storage sugars stachyose and raffinose (galactosyl derivatives of sucrose) are metabolized early during germination of soybean [Glycine max (L.) Merr.] seeds. The activities of four enzymes involved in the catabolism of these sugars were monitored in soybean cotyledons and embryonic axes during a 7-day germination period. An increase in enzyme activities correlated with a decline in galactosyl sugars. In embryonic axes, uridine diphosphate glucose (UDPglc)-hexose-l-P uridyltransferase (EC 2.7.7.12), an enzyme characteristic of the Leloir pathway, predominated over galactose-1-phosphate uridyltransferase (EC 2.7.7.10), an enzyme characteristic of the pyrophosphorylase pathway; whereas in cotyledons, the situation was reversed. There were differences between two cultivars. Ransom and Amsoy, in the levels of UDPglc-4-epimerase (EC 5.1.3.2); but not in glucose-1-phosphate uridyltransferase (EC 2 7.7.9). An accelerated aging treatment had a significant effect on the development of embryonic axes, as measured by dry weight. In vitro aging of seeds reduced the rate of growth and resulted in higher levels of galactose-containing sugars and significantly lower levels of UDPglc-hexose-l-P uridyltransferase. Thus, reduced development may be related to inability to mobilize or utilize stored carbon reserves. However, it has not been proved that the reduced enzyme activity is responsible for the effects of accelerated aging on growth and sugar metabolism.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Studies were conducted to identify and compare diurnal changes in sucrose phosphate synthase (EC 2.4.1.14) activity in leaves of different species, and the effect of nitrogen nutrition on the rhythm in soybean [Glycine max (L). Merr] leaves. In recently expanded corn (Zea mays L.) leaves, a single peak of enzyme activity was observed at the beginning of the photoperiod. A similar pattern was observed in older corn leaves, but activities (leaf fresh weight basis) were lower. In recently expanded pea (Pisum sativum L.) and soybean leaves, two peaks of sucrose phosphate synthase activity were observed over a 24-h light:dark period, one at the beginning and one at the end of the photoperiod. A similar pattern was observed in older soybean leaves, but activities were generally lower and the amplitude of the changes was reduced. In a separate experiment, soybean plants were grown in the greenhouse with either 2 or 10 mM nitrate. The high-N plants had higher rates of photosynthesis and translocation, and greater activities of sucrose phosphate synthase in leaf extracts, compared to low-N plants. Over both experiments with soybeans, changes in sucrose phosphate synthase activity during the photoperiod were closely aligned with changes in translocation rate.Type of Medium: Electronic ResourceURL: