Search Results - (Author, Cooperation:S. Howell)
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1Latest Papers from Table of Contents or Articles in PressRichards-Belle, A., Mouncey, P. R., Wade, D., Brewin, C. R., Emerson, L. M., Grieve, R., Harrison, D. A., Harvey, S., Howell, D., Mythen, M., Sadique, Z., Smyth, D., Weinman, J., Welch, J., Rowan, K. M., On behalf of the POPPI Trial Investigators
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-02-09Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Intensive care, Open accessPublished by: -
2Latest Papers from Table of Contents or Articles in PressJ. A. Olive ; M. D. Behn ; G. Ito ; W. R. Buck ; J. Escartin ; S. Howell
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-10-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressM. Rolland ; P. T. Edlefsen ; B. B. Larsen ; S. Tovanabutra ; E. Sanders-Buell ; T. Hertz ; A. C. deCamp ; C. Carrico ; S. Menis ; C. A. Magaret ; H. Ahmed ; M. Juraska ; L. Chen ; P. Konopa ; S. Nariya ; J. N. Stoddard ; K. Wong ; H. Zhao ; W. Deng ; B. S. Maust ; M. Bose ; S. Howell ; A. Bates ; M. Lazzaro ; A. O'Sullivan ; E. Lei ; A. Bradfield ; G. Ibitamuno ; V. Assawadarachai ; R. J. O'Connell ; M. S. deSouza ; S. Nitayaphan ; S. Rerks-Ngarm ; M. L. Robb ; J. S. McLellan ; I. Georgiev ; P. D. Kwong ; J. M. Carlson ; N. L. Michael ; W. R. Schief ; P. B. Gilbert ; J. I. Mullins ; J. H. Kim
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AIDS Vaccines/adverse effects/*immunology ; Genetic Predisposition to Disease ; HIV Antibodies/immunology ; HIV Infections/immunology/*prevention & control/*virology ; HIV-1/*genetics/*immunology ; Humans ; Molecular Sequence Data ; Phylogeny ; Randomized Controlled Trials as Topic ; Sequence Analysis, DNA ; env Gene Products, Human Immunodeficiency Virus/*genetics/*immunologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressB. Stieglitz ; R. R. Rana ; M. G. Koliopoulos ; A. C. Morris-Davies ; V. Schaeffer ; E. Christodoulou ; S. Howell ; N. R. Brown ; I. Dikic ; K. Rittinger
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-10-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Apoproteins/chemistry/metabolism ; Catalytic Domain ; Crystallography, X-Ray ; HeLa Cells ; Humans ; Models, Molecular ; Protein Conformation ; Substrate Specificity ; Ubiquitin/*chemistry/*metabolism ; Ubiquitin-Protein Ligases/*chemistry/*metabolismPublished by: -
5FIS Bildung LiteraturdatenbankStaff View
Type of Medium: bookPublication Date: 2003Keywords: Schulreform ; Baltimore, Md.Language: EnglishNote: Literaturangaben -
6FIS Bildung LiteraturdatenbankStaff View
Type of Medium: bookPublication Date: 2010Keywords: Schule ; Rassenintegration ; Rassismus ; Baltimore, Md.Language: English -
7Latest Papers from Table of Contents or Articles in PressNapolitano, A., van der Veen, A. G., Bunyan, M., Borg, A., Frith, D., Howell, S., Kjaer, S., Beling, A., Snijders, A. P., Knobeloch, K.-P., Frickel, E.-M.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-07-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
8Articles: DFG German National LicensesStaff View
ISSN: 1475-682XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: SociologyType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1467-8691Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: EconomicsNotes: Attitudes to neural nets range from suspicion to uncritical admiration. This paper aims to introduce nets and to evaluate their strengths and weaknesses. The language is non-technical, but the conceptual treatment is intended to be rigorous. A practical method for implementing a neural net on a spreadsheet is described, and sample results illustrated.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesWINDSOR, A. ; FRENCH, G. W. G. ; SEAR, J. W. ; FOËX, P. ; MILLETT, S. V. ; HOWELL, S. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Ninety four patients undergoing transurethral resection of the prostate underwent Holter electrocardiographic monitoring pre-and postoperatively. There was no difference in silent myocardial ischaemia incidence or load between the spinal (n = 60) ami the general anaesthesia (n = 34) groups. Ischaemic heart disease and a higher Detsky score both significantly increased the incidence of silent myocardial ischaemia but not the ischaemic load of those patients that actually demonstrated ischaemia. In this specific surgical population, not undergoing cardiac or vascular surgery, both ischaemic heart disease and cardiac risk scores are poor predictors of ischaemic load. Merely the presence of short duration silent myocardial ischaemia probably has little predictive value for postoperative adverse outcome.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesHOWELL, S. J. ; SEAR, Y. M. ; YEATES, D. ; GOLDACRE, M. ; SEAR, J. W. ; FOËX, P.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We performed a retrospective case-control study to investigate hypertension and admission blood pressure as risk factors for postoperative cardiovascular death. We identified records of 76 patients who had died of a cardiovascular cause within 30 days of anaesthesia and elective surgery and 76 matched controls. From the records of each patient (case and control) we recorded the admission blood pressure and details of any history of hypertension. A pre-operative history of hypertension was strongly associated with perioperative cardiovascular death (p 〈 0.001 with one degree of freedom: odds ratio 4.14, 95% confidence intervals 1.63–11.69). There was no association between systolic or diastolic pressure at admission for operation and perioperative cardiovascular death. The mean admission systolic pressure of the cases was 145.5 mmHg (range 90–250 mmHg) and that of the controls was 146.5 mmHg (range 100–200 mmHg). The mean admission diastolic pressure of the cases was 83.2 mmHg (range 60–130 mmHg), and that of the controls was 84.5 mmHg (range 60–110 mmHg).Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesMILLS, G. H. ; HOWELL, S. J. L. ; RICHMOND, M. N.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A patient developed spinal cord compression following epidural analgesia. The diagnosis was made difficult by the presence of epidural analgesia, although the compression was not in fact related to the analgesic technique employed. This case highlights the need for close observation of patients in whom epidural analgesia is, or has recently been, employed and the need to consider alternative reasons for neurological deficit.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesWigfull, J. ; Harding, R. ; Mallick, A. ; Howell, S.
Oxford, UK : Blackwell Science Ltd
Published 2002Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We have studied core temperature changes occurring during induction of general anaesthesia and surgery in 18 patients undergoing elective aortic aneurysm repair. In the operating theatre, all patients were warmed with a forced-air warmer and a warming mattress, and received warmed (37 °C) intravenous fluids. Despite this, mean (SD) [range] core temperatures in the anaesthetic room decreased by 1.5 (0.3)[1.1–2.2] °C, while intravascular lines, epidural and urinary catheters were inserted before the introduction of warming methods in theatre. In one-third of patients, the core temperature was still below 36 °C at the end of surgery. The overall temperature decrease correlated significantly with the duration of time between induction of general anaesthesia and surgical incision (R2 = 0.6912), when the patients were not being warmed. Hypothermia may thus be prevented by minimising the period that the patient is anaesthetised without being warmed. Vascular lines, urinary and epidural catheters should be inserted before the induction of general anaesthesia or, alternatively, warming methods should be introduced in the anaesthetic room.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesFrench, G. W. G. ; Lam, W. H. ; Rashid, Z. ; Sear, J. W. ; Foëx, P. ; Howell, S.
Oxford : Blackwell Science Ltd
Published 1999Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: One hundred and twenty-seven patients undergoing major lower limb joint replacement surgery were studied to determine the incidence of silent myocardial ischaemia and to ascertain any link between pre-operative cardiac risk factors, silent myocardial ischaemia and postoperative morbidity. Patients underwent ambulatory ECG monitoring for 4 days (on the pre-operative night and for 3 days postoperatively). Postoperative cardiorespiratory symptomatology and morbidity was assessed by questionnaire at 3 months. Eighty-seven patients had risk factors for silent myocardial ischaemia; 42 patients (30 with risk factors) had peri-operative silent myocardial ischaemia. The median ischaemic loads (range) were 1.04 (0.32–13.31) min.h−1 pre-operatively and 5.53 (0.26–56.39), 6.69 (0.04–42.71) and 1.23 (0.1–53.74) min.h−1 on postoperative days 1–3, respectively. Risk factors did not predict the occurrence of silent myocardial ischaemia or an increased ischaemic load pre-operatively or overall postoperatively. New symptoms (chest pain, palpitations, breathlessness or fatigue) were associated with both silent myocardial ischaemia and ischaemic load (p 〈 0.05). Thus cardiac risk factors do not predict the occurrence of silent myocardial ischaemia or adverse outcome. Peri-operative silent myocardial ischaemia was associated with increased postoperative fatigue.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesBANERJEE, S.S. ; HARRIS, M. ; EYDEN, B.P. ; HOWELL, S. ; WELLS, S. ; MAINWARING, A.R.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesHowell, S. J. ; Hemming, A. E. ; Allman, K. G. ; Glover, L. ; Sear, J. W. ; Foe¨x, P.
Oxford : Blackwell Science Ltd
Published 1997Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: One hundred and eighty-three patients were studied to examine the role of a number of risk factors in the development of silent ischaemia after general anaesthesia for general and vascular surgery. We collected evidence of cardiovascular risk factors using a binary questionnaire. The patients were monitored pre- and postoperatively using a Holter ECG monitor. Usable data were collected on 140 patients. Pre-operative silent myocardial ischaemia was found to be strongly associated with postoperative silent myocardial ischaemia (odds ratio: 10.8, 95% confidence intervals: 3.8–30.7). A history of hypertension, indicated by treatment with antihypertensive drugs, was associated with increased risk (odds ratio: 2.58, 95% confidence intervals: 1.12–5.96). A linear trend was found for risk associated with increasing admission systolic blood pressure (odds ratio: 1.20 for each 10-mmHg increase in systolic pressure, 95% confidence intervals: 1.01–1.42). An association between vascular surgery and postoperative silent myocardial ischaemia was also confirmed (odds ratio: 2.36, 95% confidence intervals: 1.1–5.1).Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Pulse oximetry is a powerful tool for patient monitoring but there are practical problems with its application in small children. Standard probes may be too large to be used easily and dedicated paediatric probes may be awkward to apply. The authors describe a modification of the Nellcor ‘Oxiband’ probe which simplifies its use in children. The modified probe was compared in 27 children with the conventional ‘clothes-peg’ type of device and found to under-read by 1.5% with 95% confidence intervals of ±3.1%. This is comparable to the error of the ‘Oxiband’ probe in normal use of ±3% over the range of saturations 70–95%. It is concluded that the modified probe may safely be used in clinical practice.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesLos, G. ; Johnson, A. ; Yang, F. ; Berry, C. ; Howell, S.
[s.l.] : Nature America, Inc.
Published 1999Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] Acquired resistance to cDDP (cisplatin, a cytostatic drug) appears to be a multi-factorial process and is likely to be the result of an altered gene expression pattern. The goal of this study is to profile such an expression pattern by identifying genes whose mRNA levels are differentially ...Type of Medium: Electronic ResourceURL: