Search Results - (Author, Cooperation:S. Hawkins)
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1Latest Papers from Table of Contents or Articles in PressEpidurals in Pancreatic Resection Outcomes (E-PRO) study: protocol for a randomised controlled trialPak, L. M., Haroutounian, S., Hawkins, W. G., Worley, L., Kurtz, M., Frey, K., Karanikolas, M., Swarm, R. A., Bottros, M. M.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-01-28Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, AnaesthesiaPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-02-21Publisher: Wiley-BlackwellPrint ISSN: 0008-543XElectronic ISSN: 1097-0142Topics: BiologyMedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressJoseph E. Carrara, Christopher A. Walter, Jennifer S. Hawkins, William T. Peterjohn, Colin Averill, Edward R. Brzostek
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-03-06Publisher: Wiley-BlackwellPrint ISSN: 1354-1013Electronic ISSN: 1365-2486Topics: BiologyEnergy, Environment Protection, Nuclear Power EngineeringGeographyPublished by: -
4Latest Papers from Table of Contents or Articles in PressS. Sawcer ; G. Hellenthal ; M. Pirinen ; C. C. Spencer ; N. A. Patsopoulos ; L. Moutsianas ; A. Dilthey ; Z. Su ; C. Freeman ; S. E. Hunt ; S. Edkins ; E. Gray ; D. R. Booth ; S. C. Potter ; A. Goris ; G. Band ; A. B. Oturai ; A. Strange ; J. Saarela ; C. Bellenguez ; B. Fontaine ; M. Gillman ; B. Hemmer ; R. Gwilliam ; F. Zipp ; A. Jayakumar ; R. Martin ; S. Leslie ; S. Hawkins ; E. Giannoulatou ; S. D'Alfonso ; H. Blackburn ; F. Martinelli Boneschi ; J. Liddle ; H. F. Harbo ; M. L. Perez ; A. Spurkland ; M. J. Waller ; M. P. Mycko ; M. Ricketts ; M. Comabella ; N. Hammond ; I. Kockum ; O. T. McCann ; M. Ban ; P. Whittaker ; A. Kemppinen ; P. Weston ; C. Hawkins ; S. Widaa ; J. Zajicek ; S. Dronov ; N. Robertson ; S. J. Bumpstead ; L. F. Barcellos ; R. Ravindrarajah ; R. Abraham ; L. Alfredsson ; K. Ardlie ; C. Aubin ; A. Baker ; K. Baker ; S. E. Baranzini ; L. Bergamaschi ; R. Bergamaschi ; A. Bernstein ; A. Berthele ; M. Boggild ; J. P. Bradfield ; D. Brassat ; S. A. Broadley ; D. Buck ; H. Butzkueven ; R. Capra ; W. M. Carroll ; P. Cavalla ; E. G. Celius ; S. Cepok ; R. Chiavacci ; F. Clerget-Darpoux ; K. Clysters ; G. Comi ; M. Cossburn ; I. Cournu-Rebeix ; M. B. Cox ; W. Cozen ; B. A. Cree ; A. H. Cross ; D. Cusi ; M. J. Daly ; E. Davis ; P. I. de Bakker ; M. Debouverie ; B. D'Hooghe M ; K. Dixon ; R. Dobosi ; B. Dubois ; D. Ellinghaus ; I. Elovaara ; F. Esposito ; C. Fontenille ; S. Foote ; A. Franke ; D. Galimberti ; A. Ghezzi ; J. Glessner ; R. Gomez ; O. Gout ; C. Graham ; S. F. Grant ; F. R. Guerini ; H. Hakonarson ; P. Hall ; A. Hamsten ; H. P. Hartung ; R. N. Heard ; S. Heath ; J. Hobart ; M. Hoshi ; C. Infante-Duarte ; G. Ingram ; W. Ingram ; T. Islam ; M. Jagodic ; M. Kabesch ; A. G. Kermode ; T. J. Kilpatrick ; C. Kim ; N. Klopp ; K. Koivisto ; M. Larsson ; M. Lathrop ; J. S. Lechner-Scott ; M. A. Leone ; V. Leppa ; U. Liljedahl ; I. L. Bomfim ; R. R. Lincoln ; J. Link ; J. Liu ; A. R. Lorentzen ; S. Lupoli ; F. Macciardi ; T. Mack ; M. Marriott ; V. Martinelli ; D. Mason ; J. L. McCauley ; F. Mentch ; I. L. Mero ; T. Mihalova ; X. Montalban ; J. Mottershead ; K. M. Myhr ; P. Naldi ; W. Ollier ; A. Page ; A. Palotie ; J. Pelletier ; L. Piccio ; T. Pickersgill ; F. Piehl ; S. Pobywajlo ; H. L. Quach ; P. P. Ramsay ; M. Reunanen ; R. Reynolds ; J. D. Rioux ; M. Rodegher ; S. Roesner ; J. P. Rubio ; I. M. Ruckert ; M. Salvetti ; E. Salvi ; A. Santaniello ; C. A. Schaefer ; S. Schreiber ; C. Schulze ; R. J. Scott ; F. Sellebjerg ; K. W. Selmaj ; D. Sexton ; L. Shen ; B. Simms-Acuna ; S. Skidmore ; P. M. Sleiman ; C. Smestad ; P. S. Sorensen ; H. B. Sondergaard ; J. Stankovich ; R. C. Strange ; A. M. Sulonen ; E. Sundqvist ; A. C. Syvanen ; F. Taddeo ; B. Taylor ; J. M. Blackwell ; P. Tienari ; E. Bramon ; A. Tourbah ; M. A. Brown ; E. Tronczynska ; J. P. Casas ; N. Tubridy ; A. Corvin ; J. Vickery ; J. Jankowski ; P. Villoslada ; H. S. Markus ; K. Wang ; C. G. Mathew ; J. Wason ; C. N. Palmer ; H. E. Wichmann ; R. Plomin ; E. Willoughby ; A. Rautanen ; J. Winkelmann ; M. Wittig ; R. C. Trembath ; J. Yaouanq ; A. C. Viswanathan ; H. Zhang ; N. W. Wood ; R. Zuvich ; P. Deloukas ; C. Langford ; A. Duncanson ; J. R. Oksenberg ; M. A. Pericak-Vance ; J. L. Haines ; T. Olsson ; J. Hillert ; A. J. Ivinson ; P. L. De Jager ; L. Peltonen ; G. J. Stewart ; D. A. Hafler ; S. L. Hauser ; G. McVean ; P. Donnelly ; A. Compston
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-08-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Differentiation/immunology ; Europe/ethnology ; Genetic Predisposition to Disease/*genetics ; Genome, Human/genetics ; Genome-Wide Association Study ; HLA-A Antigens/genetics ; HLA-DR Antigens/genetics ; HLA-DRB1 Chains ; Humans ; Immunity, Cellular/genetics/*immunology ; Major Histocompatibility Complex/genetics ; Multiple Sclerosis/*genetics/*immunology ; Polymorphism, Single Nucleotide/genetics ; Sample Size ; T-Lymphocytes, Helper-Inducer/cytology/immunologyPublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1365-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The milk yields obtained from 845 herd-years within the ICI Recorded Farms Scheme have been correlated, by multiple regression analysis, with the N fertilizer supplied to the grassland, the quantities of concentrates fed and the stocking rates. The large quantity of data gave highly significant correlations which indicated that, over the whole period, the supply of an extra 1 kg N from fertilizer was associated with an average extra yield of 9·9 1 milk. 4·9 1 were associated with the extra N independently of any simultaneous changes in either stocking rate or concentrate feeding, and 4-5 1 were ascribable to a simultaneous increase in stocking rate. There was a substantial variation in the ‘milk yield per kg N’ response from year to year, but the average value over 6 years agreed closely with that observed in the period 1949–52.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesCOX, D. ; HAWKINS, S. L. ; HARTLEY, C. E. ; MYLOTTE, M. J. ; SKINNER, G. R. B.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. Neutralizing and radioimmunobinding antibody against type 1 herpes simplex virus was detected in about 50% of amniotic fluid samples. The occurrence and levels of antibody activity correlated with neutralizing and immunoprecipitating antibody activity in the sera of these subjects.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesChauvet, M. ; Hawkins, S. A. ; Salamo, G. J.
Woodbury, NY : American Institute of Physics (AIP)
Published 1997Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We demonstrated an experimental observation of self-trapping and self-deflection of a two-dimensional optical beam by the photorefractive effect at telecommunication wavelengths under an applied dc field. Self-trapping is effective for an intensity range related to the intensity-temperature resonance known for two-wave mixing in InP:Fe. The photorefractive index change giving rise to the trapping is measured at 10−4, while the photorefractive space-charge field is measured at about 50 kV/cm, ten times higher than the applied field. We show experimentally that this index change creates a waveguide that can be used to guide a second beam at 1.55 μm. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesHendry, K. ; Conlan, K. ; White, K. N. ; Bewsher, A. ; Hawkins, S. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesDavey, A. J. H. ; Hawkins, S. J. ; Turner, G. F. ; Doncaster, C. P.
Oxford, UK; Malden, USA : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: An electrofishing survey of daytime shelter microhabitat use of bullhead Cottus gobio in a southern English chalk stream revealed positive selection for moderate water velocity, vegetation cover and coarse substrata. Water depth, other forms of cover, shade and substratum embeddedness had no significant influence on the distribution of fish. Microhabitat use was size-dependent, with patches occupied by adult fish containing coarser substrata and less blanket weed (Cladophora algae) than those occupied by smaller juvenile conspecifics. Differences in substratum use between size-classes were less pronounced in parts of the stream shaded by the tree canopy. In laboratory tanks stocked at low fish density, both juveniles and adults favoured use of cobbles over pebbles. The response of fish to increased conspecific density was size-dependent; juveniles reduced use of the coarse substratum whereas adults maintained their predominance in this habitat. An apparently greater shift by juveniles when in the presence of adults was significant at α = 0·10 only, as was an apparent reduction in interactions between size-classes under low light intensity. The displacement of small juvenile fish from the preferred cobble substratum is consistent with the hypothesis that intraspecific competition contributes to the size-related microhabitat shift observed in the field. Although there was a tendency for the strength of competition to be reduced at low light levels, the mechanism by which tree canopy cover affects microhabitat use remains uncertain.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesHawkins, S. L. ; Varnavskaya, N. V. ; Matzak, E. A. ; Efremov, V. V. ; Guthrie, C. M. ; Wilmot, R. L. ; Mayama, H. ; Yamazaki, F. ; Gharrett, A. J.
Oxford, UK : Blackwell Publishing Ltd
Published 2002Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Most of the variation (99%) of Asian odd-broodline pink salmon Oncorhynchus gorbuscha, based on data at 32 variable (46 total) allozyme loci from 35 populations, occurred within populations. The remaining interpopulation variation was attributable to: (1) differences between northern (the northern Sea of Okhotsk, eastern Kamchatka Peninsula and western Kamchatka Peninsula) and southern (Hokkaido Island, Kuril Islands and Sakhalin Island) populations; (2) differences between the southern areas; (3) low variation among populations within some areas. The pattern contrasted strongly with that observed for Asian even-broodline populations, which had a strong structure, possibly related to geographic and oceanographic influences. Isolation-by-distance analyses of each of the two broodlines showed a stronger relationship (x 4·8) among even- than odd-broodline populations. Allele frequency differences between even- and odd-broodlines reflected the reproductive isolation of the broodlines. However, there were no fixed frequency differences which, considered with the differing population structures, suggests that migration-drift equilibrium has not yet obtained in one or both broodlines. The structural differences also suggest it is likely that the even- and odd-broodlines are of different ages and that one is derived from the other. Allozyme data do not provide a genealogical basis for identifying the ancestral lineage.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesConlan, K. ; Hendry, K. ; White, K. N. ; Hawkins, S. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: A netting and hydrographic study of Preston dock was undertaken between May 1987 and April 1988. Fish populations were assessed using Lundgren monofilament multimesh gillnets. The dock was a low-salinity environment regularly replenished with estuarine water on spring tides. Influxes of higher-salinity water caused intermittent saline wedges in the deeper regions. The dock water was poorly mixed in the summer, resulting in bottom water anoxia. The water was eutrophic, and blue-green algal blooms were common for much of the year.Fourteen freshwater, marine-estuarine, anadromous and catadromous species were present in the dock. No seasonal patterns in diversity were apparent, due to the dominance of the herring population. Changes in species composition and abundance seem to relate to seasonal migratory patterns and, in the case of the freshwater fish, estuarine salinity, rather than to water quality.The suitablity of docks for sampling estuarine fish assemblages is discussed.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesSantos, R. S. ; Hawkins, S. J. ; Nash, R. D. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Both male and female Parablennius sanguinolentus parvicornis were ready to mate by the end of May. Seventy-five per cent of the 1-year-old males were mature, but only 25% of the females reached maturity at this age. In females, gonads formed an increasingly greater proportion of the total weight with age, but in males the proportion decreased. A bimodal distribution of gonadosomatic indices classes was observed in 2-year-old males (intermediate size), which reflected the lower opportunity that intermediate size males have to spend the ejaculates than have the younger and older males. The liver played an important role in the storage of energy before the reproductive season and reserves were utilized during the breeding season. Physical condition was at its lowest in July in both sexes, but in May, just before the breeding season began, large maturing females had significantly lower eviscerated condition than males. This could be due to females investing in oocyte development, while the priority for the males was to reserve their energy for the parental activities to come. In both males and females, older and bigger animals had lower hepatosomatic and body conditions than younger ones.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Clear changes in body size-isotope (carbon and nitrogen) trajectories of Pseudotropheus callainos, a cichlid belonging to the endemic haplochromine species radiation in Lake Malawi, were found that corresponded with an ontogenetic dietary shift from predominantly planktonic to benthic food sources. The results indicated that dietary switching was a proximate cause of isotopic change over the life history of this species and confirmed the value of stable isotope signatures for inferring diet. The data also illustrated that possible variability of signatures over the life history of a species should be considered when using stable isotope ratios to investigate fine-scale ecological differentiation among taxa.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesSuppiah, V. ; Goris, A. ; Alloza, I. ; Heggarty, S. ; Dubois, B. ; Carton, H. ; Antigüedad, A. ; Mendibe, M. ; McDonnell, G. ; Droogan, A. ; Hawkins, S. ; Graham, C. ; Vandenbroeck, K.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Cytokine gene polymorphisms are known to influence susceptibility and disease course of many autoimmune diseases. Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system white matter characterized by inflammation, demyelination and axonal damage. We analysed both the well-known intronic variable number of tandem repeat (VNTR) and +33 C/T single-nucleotide polymorphisms (SNP) in the IL-4 gene, as well as the functional Q551R SNP in the IL4-R gene in a cohort of three distinct populations comprising sporadic cases and controls from the northern Spanish Basque Country and Northern Ireland, as well as family trios from Belgium. The IL-4 +33 TT genotype was decreased in primary progressive (PP) versus relapsing-remitting (RR) patients in the Northern Irish population (OR = 0.14; 95% CI = 0.018–1.09). Two-marker haplotype distribution of the VNTR and +33 C/T SNP in PP patients differed from that seen in RR patients in Northern Ireland (P = 0.03). The R allele of the Q551R SNP was significantly under-transmitted in the Belgian trio families (P = 0.003), although this effect was not seen in the Northern Irish and Basque data sets. We did not identify IL-4–IL4-R gene–gene interaction in determining susceptibility or clinical parameters of MS. Disease or genetic heterogeneity or both may be responsible for the observed lack of reproduction in different populations. Our data reinforce recent findings for a role of IL4-R in susceptibility to MS.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Guided by such conceptions, we have examined the effect on dividing cells in roots of Allium cepa of some gaseous narcotics propane, nitrous oxide, argon, nitrogen, etc. applied at sufficient pressure, that is, at sufficient concentration, to reach values of thermodynamic activity of the effective ...Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesComoy, E. ; Hawkins, S. ; Simon, S. ; Schimmel, H. ; Wells, G. ; Grassi, J. ; Moynagh, J. ; Deslys, J. P.
[s.l.] : Nature Publishing Group
Published 2001Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The systematic testing of slaughtered cattle aged over 30 months, or alternatively their elimination from the food chain, is an important component of a package of measures introduced in the European Union on 1 January 2001 to combat bovine spongiform encephalopathy (BSE) and protect human ...Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0031-9163Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesMiddleton, D. ; Savage, D. A. ; Cullen, C. ; Trainor, F. ; Mallon, E. ; Hawkins, S.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Using sequence-specific oligonucleotide probes, no altered distribution in the frequency of HLA-DPB1 alleles was found in multiple sclerosis patients from Northern Ireland. Although present in the controls, linkage disequilibrium between HLA-DPB1*0101 and HLA-DR17 was not found in multiple sclerosis patients.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesHawkins, S. J. ; Black, C. M. ; Hall, N. D. ; McGregor, A. ; Ring, E. F. J. ; Maddison, P. J.
Springer
Published 1986Staff ViewISSN: 1437-160XKeywords: Raynaud's phenomenon ; Nifedipine ; Calcium channel blockersSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The calcium channel blocking drug nifedipine was shown to be more effective than placebo as a treatment for Raynaud's phenomenon. Given in a dose of 10 mg four times a day it was well tolerated and reduced both the frequency and the severity of vasospastic attacks. There was, however, a large individual variation in response and while approximately half the patients showed marked improvement others showed no improvement at all. Patients with idiopathic Raynaud's phenomenon responded more favourably than those with systemic sclerosis. Nifedipine was shown to inhibit mitogen-induced lymphocyte proliferation but only in patients who responded to the drug clinically. Calcium channel blocking drugs may therefore have potential as immunoregulatory agents.Type of Medium: Electronic ResourceURL: