Search Results - (Author, Cooperation:S. H. Chen)
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1Wang, X., Zhang, X., Chu, E. S. H., Chen, X., Kang, W., Wu, F., To, K.-F., Wong, V. W. S., Chan, H. L. Y., Chan, M. T. V., Sung, J. J. Y., Wu, W. K. K., Yu, J.
The Federation of American Societies for Experimental Biology (FASEB)
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: The Federation of American Societies for Experimental Biology (FASEB)Print ISSN: 0892-6638Electronic ISSN: 1530-6860Topics: BiologyPublished by: -
2H. F. Zheng ; V. Forgetta ; Y. H. Hsu ; K. Estrada ; A. Rosello-Diez ; P. J. Leo ; C. L. Dahia ; K. H. Park-Min ; J. H. Tobias ; C. Kooperberg ; A. Kleinman ; U. Styrkarsdottir ; C. T. Liu ; C. Uggla ; D. S. Evans ; C. M. Nielson ; K. Walter ; U. Pettersson-Kymmer ; S. McCarthy ; J. Eriksson ; T. Kwan ; M. Jhamai ; K. Trajanoska ; Y. Memari ; J. Min ; J. Huang ; P. Danecek ; B. Wilmot ; R. Li ; W. C. Chou ; L. E. Mokry ; A. Moayyeri ; M. Claussnitzer ; C. H. Cheng ; W. Cheung ; C. Medina-Gomez ; B. Ge ; S. H. Chen ; K. Choi ; L. Oei ; J. Fraser ; R. Kraaij ; M. A. Hibbs ; C. L. Gregson ; D. Paquette ; A. Hofman ; C. Wibom ; G. J. Tranah ; M. Marshall ; B. B. Gardiner ; K. Cremin ; P. Auer ; L. Hsu ; S. Ring ; J. Y. Tung ; G. Thorleifsson ; A. W. Enneman ; N. M. van Schoor ; L. C. de Groot ; N. van der Velde ; B. Melin ; J. P. Kemp ; C. Christiansen ; A. Sayers ; Y. Zhou ; S. Calderari ; J. van Rooij ; C. Carlson ; U. Peters ; S. Berlivet ; J. Dostie ; A. G. Uitterlinden ; S. R. Williams ; C. Farber ; D. Grinberg ; A. Z. LaCroix ; J. Haessler ; D. I. Chasman ; F. Giulianini ; L. M. Rose ; P. M. Ridker ; J. A. Eisman ; T. V. Nguyen ; J. R. Center ; X. Nogues ; N. Garcia-Giralt ; L. L. Launer ; V. Gudnason ; D. Mellstrom ; L. Vandenput ; N. Amin ; C. M. van Duijn ; M. K. Karlsson ; O. Ljunggren ; O. Svensson ; G. Hallmans ; F. Rousseau ; S. Giroux ; J. Bussiere ; P. P. Arp ; F. Koromani ; R. L. Prince ; J. R. Lewis ; B. L. Langdahl ; A. P. Hermann ; J. E. Jensen ; S. Kaptoge ; K. T. Khaw ; J. Reeve ; M. M. Formosa ; A. Xuereb-Anastasi ; K. Akesson ; F. E. McGuigan ; G. Garg ; J. M. Olmos ; M. T. Zarrabeitia ; J. A. Riancho ; S. H. Ralston ; N. Alonso ; X. Jiang ; D. Goltzman ; T. Pastinen ; E. Grundberg ; D. Gauguier ; E. S. Orwoll ; D. Karasik ; G. Davey-Smith ; A. V. Smith ; K. Siggeirsdottir ; T. B. Harris ; M. C. Zillikens ; J. B. van Meurs ; U. Thorsteinsdottir ; M. T. Maurano ; N. J. Timpson ; N. Soranzo ; R. Durbin ; S. G. Wilson ; E. E. Ntzani ; M. A. Brown ; K. Stefansson ; D. A. Hinds ; T. Spector ; L. A. Cupples ; C. Ohlsson ; C. M. Greenwood ; R. D. Jackson ; D. W. Rowe ; C. A. Loomis ; D. M. Evans ; C. L. Ackert-Bicknell ; A. L. Joyner ; E. L. Duncan ; D. P. Kiel ; F. Rivadeneira ; J. B. Richards
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-09-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bone Density/*genetics ; Bone and Bones/metabolism ; Disease Models, Animal ; Europe/ethnology ; European Continental Ancestry Group/genetics ; Exome/genetics ; Female ; Fractures, Bone/*genetics ; Gene Frequency/genetics ; Genetic Predisposition to Disease/genetics ; Genetic Variation/genetics ; Genome, Human/*genetics ; Genomics ; Genotype ; Homeodomain Proteins/*genetics ; Humans ; Mice ; Sequence Analysis, DNA ; Wnt Proteins/geneticsPublished by: -
3Coker, O. O., Dai, Z., Nie, Y., Zhao, G., Cao, L., Nakatsu, G., Wu, W. K., Wong, S. H., Chen, Z., Sung, J. J. Y., Yu, J.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-05-09Publisher: BMJ Publishing GroupPrint ISSN: 0017-5749Electronic ISSN: 1468-3288Topics: MedicineKeywords: Open access, Editor's choice, GutPublished by: -
4S. H. Chen ; W. Forrester ; G. Lahav
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-03-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Antineoplastic Agents/*administration & dosage ; Apoptosis ; *DNA Damage ; Gene Knockdown Techniques ; Humans ; MCF-7 Cells ; Molecular Imaging ; Neoplasms/*drug therapy ; Proto-Oncogene Proteins c-mdm2/*antagonists & inhibitors/genetics ; RNA, Small Interfering/genetics ; Signal Transduction ; Time Factors ; Tumor Suppressor Protein p53/*metabolismPublished by: -
5J. Zheng ; M. Umikawa ; C. Cui ; J. Li ; X. Chen ; C. Zhang ; H. Huynh ; X. Kang ; R. Silvany ; X. Wan ; J. Ye ; A. P. Canto ; S. H. Chen ; H. Y. Wang ; E. S. Ward ; C. C. Zhang
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Differentiation ; Cell Division ; Cells, Cultured ; Disease Models, Animal ; Fetal Blood/cytology/metabolism ; HEK293 Cells ; Hematopoietic Stem Cells/*cytology/*metabolism ; Humans ; Leukemia/*metabolism/*pathology ; Membrane Glycoproteins/genetics/*metabolism ; Mice ; Myeloid-Lymphoid Leukemia Protein ; Receptors, Immunologic/genetics/*metabolismPublished by: -
6P. Han ; W. Li ; C. H. Lin ; J. Yang ; C. Shang ; S. T. Nurnberg ; K. K. Jin ; W. Xu ; C. Y. Lin ; C. J. Lin ; Y. Xiong ; H. C. Chien ; B. Zhou ; E. Ashley ; D. Bernstein ; P. S. Chen ; H. S. Chen ; T. Quertermous ; C. P. Chang
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cardiac Myosins/genetics ; Cardiomegaly/*genetics/*pathology/prevention & control ; Cardiomyopathies/genetics/pathology/prevention & control ; Chromatin/genetics/metabolism ; Chromatin Assembly and Disassembly ; DNA Helicases/antagonists & inhibitors/chemistry/genetics/metabolism ; Feedback, Physiological ; Heart Failure/genetics/pathology/prevention & control ; Histone Deacetylases/metabolism ; Humans ; Mice ; Myocardium/metabolism/pathology ; Myosin Heavy Chains/*genetics ; Nuclear Proteins/antagonists & inhibitors/chemistry/genetics/metabolism ; Organ Specificity ; Poly(ADP-ribose) Polymerases/metabolism ; Protein Binding ; Protein Structure, Tertiary ; RNA, Long Noncoding/antagonists & inhibitors/*genetics/metabolism ; Transcription Factors/antagonists & inhibitors/chemistry/genetics/metabolismPublished by: -
7Staff View
Publication Date: 2018-06-02Publisher: Institute of Physics (IOP)Print ISSN: 1674-1137Topics: PhysicsPublished by: -
8Staff View
Publication Date: 2018-02-12Publisher: Institute of Physics (IOP)Print ISSN: 1674-1137Topics: PhysicsPublished by: -
9Staff View
Publication Date: 2018-07-27Publisher: Institute of Physics (IOP)Print ISSN: 1674-1137Topics: PhysicsPublished by: -
10C. Kim ; J. Wong ; J. Wen ; S. Wang ; C. Wang ; S. Spiering ; N. G. Kan ; S. Forcales ; P. L. Puri ; T. C. Leone ; J. E. Marine ; H. Calkins ; D. P. Kelly ; D. P. Judge ; H. S. Chen
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-01-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Active Transport, Cell Nucleus ; Age of Onset ; Apoptosis/genetics ; Arrhythmogenic Right Ventricular ; Dysplasia/genetics/*metabolism/*pathology/physiopathology ; Cellular Reprogramming ; Culture Media/pharmacology ; Embryoid Bodies/drug effects/physiology ; Energy Metabolism/genetics ; Fatty Acids/metabolism ; Fibroblasts/metabolism/pathology ; Glucose/metabolism ; Glycolysis ; Humans ; Induced Pluripotent Stem Cells/metabolism/*pathology ; Lipogenesis/genetics ; *Models, Biological ; Myocardial Contraction/drug effects ; Myocytes, Cardiac/pathology ; PPAR alpha/metabolism ; PPAR gamma/metabolism ; Phenotype ; Plakophilins/genetics ; Time Factors ; beta Catenin/metabolismPublished by: -
11Afaq, A., Alahmed, S., Chen, S.-h., Lengana, T., Haroon, A., Payne, H., Ahmed, H., Punwani, S., Sathekge, M., Bomanji, J.
The Society of Nuclear Medicine (SNM)
Published 2018Staff ViewPublication Date: 2018-01-03Publisher: The Society of Nuclear Medicine (SNM)Print ISSN: 0022-3123Topics: MedicinePublished by: -
12H M Lei, F N Chen, S H Ahn, Y X Xiao, X J Zhou, C J Zeng, H G Fan and Z W Wang
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-07-31Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
13H M Lei, Y X Xiao, F N Chen, S H Ahn, Z W Wang, Z H Gui, Y Y Luo and X R Zhao
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-07-31Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
14Staff View
Publication Date: 2018-11-07Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
15van der Touw, W., Kang, K., Luan, Y., Ma, G., Mai, S., Qin, L., Bian, G., Zhang, R., Mungamuri, S. K., Hu, H.-M., Zhang, C. C., Aaronson, S. A., Feldmann, M., Yang, W.-C., Chen, S.-H., Pan, P.-Y.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-09-05Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
16Chen, S. H. ; Tung, M. J. ; Shu, W. B. ; Liu, C. S. ; Ke, M. Y.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: The working frequency of Mn-Zn ferrites in switching power supply has been increased recently. Therefore, the manufacturing Mn-Zn ferrites with low loss at high frequency is very important. However, there were few reports concerning the core loss of Mn-Zn ferrites.1 It is beneficial to study the parameters affecting the core loss of Mn-Zn ferrites. Therefore, we studied the influence of atmosphere on the hysteresis loss (Wh) and eddy current loss (We) for different compositions in this work. Three compositions, Mn0.70Zn0.21−xFe2.09+xO4 (x=0, 0.01, 0.02), were prepared by traditional ceramic process. The sintering condition is 1385 °C for 4 h. Then, the samples are annealed at 1100 °C for 24 h in different oxygen partial pressure (0.015–1.0 vol %). Experimental results show that both We and Wh have minimum value at different oxygen partial pressure for samples with different composition. Increasing Fe content which raises the Fe++ concentration shifts the We and Wh minimum point to higher annealing oxygen partial pressure. It is mainly due to the oxidation of Fe++ and the transition of conduction mechanism, and it will be further discussed later. We can obtain the lowest core loss for using 10 and 100 kHz are samples with composition x=0 annealed in 0.07 and 0.2 vol % oxygen partial pressure, respectively. Summarily, for application to low loss at different working frequency, it is found that different optimized atmosphere should be controlled during annealing for different composition.Type of Medium: Electronic ResourceURL: -
17Bradley, K. F. ; Chen, S.-H. ; Brun, T. O.
College Park, Md. : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: We report here measurements of quasielastic neutron scattering from n-butane at temperatures of 90, 115, 125 and 190 K and in a momentum transfer range of 0.8–2.4 A(ring)−1. These measurements confirm that between 115 and 125 K butane forms a plastic crystal in which the centers of mass of the butane molecules form a crystalline structure, but the individual molecules are free to rotate. At these two intermediate temperatures, there exists both an elastic peak, characteristic of a solid structure, and quasielastic components arising from the rotational motions of the butane molecules. At 90 K, the butane scatters neutrons only elastically, while at 190 K, the butane scatters neutrons only quasielastically. In both the plastic and the liquid phases, the presence of at least two quasielastic processes must be assumed in order to explain the measurements. In the plastic crystal, we associate a broad Lorentzian component with intramolecular reorientations about the central carbon–carbon bond and a second, relatively narrow, Lorentzian component with whole molecule rotations.The latter process gives rise to a rotational quasielastic peak having a width of 400 μeV, which is constant to within the instrumental resolution of 70 μeV at both temperatures and at all measured momentum transfers. In a continuous diffusion model, this width corresponds to a rotational diffusion constant of 0.277 rad2/ps, a value which is about 3.5 times larger than one extracted from a molecular dynamics simulation of n-butane in the plastic phase recently published by Refson and Pawley [Mol. Phys. 61, 669 (1987); 61, 693 (1987)]. On the other hand, the first process, which corresponds to the carbon–carbon reorientation peak, is about 16 meV wide, indicating that this reorientation occurs on a time scale of about 0.1 ps. The absence of this broad peak in the solid butane at 90 K indicates that this fast carbon–carbon reorientation is coupled to an aspect of the structure or dynamics of the plastic phase. In the scattering from liquid butane at 190 K, there is a third, narrow quasielastic peak which also has a Lorentzian energy distribution. This peak width is about 200 μeV and corresponds to a translational diffusion constant of 0.23 A(ring)2/ps, a result in rough agreement with a recent molecular dynamics simulation of liquid butane by Ullo and Yip. [J. Chem. Phys. 85, 4056 (1986)].Type of Medium: Electronic ResourceURL: -
18Chen, S.-H. ; Chang, S.-L. ; Strey, R.
College Park, Md. : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The continuous inversion from a water-in-oil (w/o) microemulsion at low temperatures to an oil-in-water (o/w) microemulsion at higher temperatures within the one-phase channel of water (0.6% NaCl)–n-decane–AOT microemulsion system is investigated by small angle neutron scattering (SANS). At constant AOT (surfactant) weight fraction γ of 12%, the structural evolution as a function of temperature takes place in different forms as the oil-to-water weight fraction α is varied from 15 to 90 %. At low o-w weight fractions (α=15 and 20 %) the microemulsions transform from a water-internal, oil-continuous structure at lower temperatures to an oil-internal, water-continuous droplet structure at higher temperatures jumping across an intermediate region of a lamellar phase (Lα). However, at higher o-w weight fractions (α=80 and 90 %) the evolution goes through a stage of percolation of the water droplets first into extended water clusters, then the structural inversion takes place probably through a transition of these water clusters into an entangled tubular structure. At equal oil-to-water volume ration (α=40%), the structure can be described as bicontinuous at both low and high temperatures. In this case we are able to extract two lengths characterizing the structure from SANS data using different models for the scattering length density fluctuation correlation function of a bicontinuous microemulsion.Type of Medium: Electronic ResourceURL: -
19Rouch, J. ; Safouane, A. ; Tartaglia, P. ; Chen, S. H.
College Park, Md. : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Extensive light scattering measurements, including the intensity, turbidity, and linewidth, on a three-component microemulsion system consisting of mixtures of water, decane, and a surfactant sodium di-2 ethylhexylsulfosuccinate (AOT) (WDA), have been made. The critical and several off-critical mixtures have been studied along constant microemulsion droplet volume fraction lines in the one-phase region over a very large temperature range. In the vicinity of the lower phase separation temperature Tp the intensity data are very well accounted for by the standard theory of critical binary fluids using a single value for the short range correlation length ξ0=(13.5±1.5) A(ring). By combining a mode-coupling theory including the background effects and a linear model equation of state applicable in the critical region, we have been able to fit the dynamic light scattering data using a Debye cutoff length q−1D which is equal to the constant average diameter of microemulsion droplets. Furthermore, we find clear evidence for a crossover from critical to single particle behavior in both static and dynamic light scattering data. A crossover temperature Tx has been identified at which qDξ(Tx)=1. Analyses of the dynamic light scattering data show that qD, which can only be measured far away from Tp, in fact plays a decisive role in controlling the critical dynamics in the whole temperature range.Type of Medium: Electronic ResourceURL: -
20Bratko, D. ; Luzar, A. ; Chen, S. H.
College Park, Md. : American Institute of Physics (AIP)
Published 1988Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Thermodynamics of protein solubilization in water-in-oil microemulsions is analyzed in terms of the shell-and-core model for reverse micelles. The electrostatic contribution to the free energy of transfer of the protein from the aqueous solution to the microemulsion is determined via the solution of the nonlinear Poisson–Boltzmann equation for the protein/reverse micelle complex, for the protein-free micelle, and for the cell model of aqueous protein solution in equilibrium with the microemulsion. The electrolyte effect on the protein solubility in the microemulsion is studied. A good agreement between the predictions of the model and the known salting out effect of cytochrome-c in sodium di-2-ethylhexylsulfosuccinate AOT-water-in-isooctane microemulsion is observed.Type of Medium: Electronic ResourceURL: