Search Results - (Author, Cooperation:S. Griffin)
-
1E. Aliu ; T. Arlen ; T. Aune ; M. Beilicke ; W. Benbow ; A. Bouvier ; S. M. Bradbury ; J. H. Buckley ; V. Bugaev ; K. Byrum ; A. Cannon ; A. Cesarini ; J. L. Christiansen ; L. Ciupik ; E. Collins-Hughes ; M. P. Connolly ; W. Cui ; R. Dickherber ; C. Duke ; M. Errando ; A. Falcone ; J. P. Finley ; G. Finnegan ; L. Fortson ; A. Furniss ; N. Galante ; D. Gall ; K. Gibbs ; G. H. Gillanders ; S. Godambe ; S. Griffin ; J. Grube ; R. Guenette ; G. Gyuk ; D. Hanna ; J. Holder ; H. Huan ; G. Hughes ; C. M. Hui ; T. B. Humensky ; A. Imran ; P. Kaaret ; N. Karlsson ; M. Kertzman ; D. Kieda ; H. Krawczynski ; F. Krennrich ; M. J. Lang ; M. Lyutikov ; A. S. Madhavan ; G. Maier ; P. Majumdar ; S. McArthur ; A. McCann ; M. McCutcheon ; P. Moriarty ; R. Mukherjee ; P. Nunez ; R. A. Ong ; M. Orr ; A. N. Otte ; N. Park ; J. S. Perkins ; F. Pizlo ; M. Pohl ; H. Prokoph ; J. Quinn ; K. Ragan ; L. C. Reyes ; P. T. Reynolds ; E. Roache ; H. J. Rose ; J. Ruppel ; D. B. Saxon ; M. Schroedter ; G. H. Sembroski ; G. D. Senturk ; A. W. Smith ; D. Staszak ; G. Tesic ; M. Theiling ; S. Thibadeau ; K. Tsurusaki ; J. Tyler ; A. Varlotta ; V. V. Vassiliev ; S. Vincent ; M. Vivier ; S. P. Wakely ; J. E. Ward ; T. C. Weekes ; A. Weinstein ; T. Weisgarber ; D. A. Williams ; B. Zitzer
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-10-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
2B. Raymond ; S. A. West ; A. S. Griffin ; M. B. Bonsall
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-07-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacillus thuringiensis/growth & development/*pathogenicity/physiology ; Bacterial Proteins/*biosynthesis/genetics ; Brassica/microbiology ; Endotoxins/*biosynthesis/genetics ; Hemolymph/microbiology ; Hemolysin Proteins/*biosynthesis/genetics ; Larva/pathogenicity/physiology ; *Microbial Interactions ; Moths/*microbiology ; Plant Leaves/*microbiology ; Virulence ; Virulence Factors/*biosynthesis/geneticsPublished by: -
3J. J. Boomsma ; M. Beekman ; C. K. Cornwallis ; A. S. Griffin ; L. Holman ; W. O. Hughes ; L. Keller ; B. P. Oldroyd ; F. L. Ratnieks
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: *Altruism ; Animals ; *Biological Evolution ; Cooperative Behavior ; Female ; Game Theory ; Genetic Fitness ; Genetics, Population ; Male ; *Models, Biological ; Reproducibility of Results ; Reproduction/physiology ; Selection, Genetic ; Sex Ratio ; *SiblingsPublished by: -
4Staff View
Publication Date: 2018-01-18Publisher: Wiley-BlackwellPrint ISSN: 0007-0963Electronic ISSN: 1365-2133Topics: MedicinePublished by: -
5Staff View
Publication Date: 2018-06-15Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Health services researchPublished by: -
6Samson, A., Bentham, M. J., Scott, K., Nuovo, G., Bloy, A., Appleton, E., Adair, R. A., Dave, R., Peckham-Cooper, A., Toogood, G., Nagamori, S., Coffey, M., Vile, R., Harrington, K., Selby, P., Errington-Mais, F., Melcher, A., Griffin, S.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-02-09Publisher: BMJ Publishing GroupPrint ISSN: 0017-5749Electronic ISSN: 1468-3288Topics: MedicineKeywords: Open accessPublished by: -
7Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We looked at the possible interactions between astrocytes and neurones during reperfusion using an in vitro model of ischaemia–reperfusion injury, as a controlled environment that lends itself easily to manipulation of the numerous variables involved in such an insult. We constructed a chamber in which O2 can be lowered to a concentration of 1 µm and developed a primary cortical neuronal culture that is 99% pure and can survive to at least 10 days in vitro. We also established a novel system for the co-culture of astrocytes and neurones in order to study the communication between these cells in a manner that allows the complete separation of one cell type from another. Neurone cultures showed profound cell death following an ischaemic period of only 15 min. We co-cultured neurones that had been subjected to a 15-min ischaemic insult with either non-insulted astrocytes or astrocyte-conditioned medium during the reperfusion stage. Both astrocytes and astrocyte-conditioned medium enhanced neuronal survival. Our data also suggest that astrocyte-sourced neuronal glutathione synthesis may play a role in preventing neuronal death.Type of Medium: Electronic ResourceURL: -
8BATE, C. M. ; GRIFFIN, S. M. ; KEELING, P. W. N. ; AXON, A. T. R. ; DRONFIELD, M. W. ; CHAPMAN, R. W. G. ; O'DONOGHUE, D. ; CALAM, J. ; CROWE, J. ; MOUNTFORD, R. A. ; WATTS, D. A. ; TAYLOR, M. D. ; RICHARDSON, P. D. I.
Oxford BSL : Blackwell Science
Published 1996Staff ViewISSN: 1365-2036Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: As many as 50% of patients with reflux symptoms have no endoscopic evidence of oesophagitis. This multicentre study was designed to assess symptom relief after omeprazole 20 mg once daily in patients with symptoms typical of gastro-oesophageal reflux disease but without endoscopic evidence of oesophagitis. Methods: Patients (n=209) were randomized in a double-blind study to receive either omeprazole 20 mg once daily (n=98) or placebo (n=111) for 4 weeks. Symptoms were assessed at clinic visits and using daily diary cards, with patient-completed questionnaires providing additional data on symptoms and on psychological disturbance. Results: On completion, symptom relief favoured omeprazole: 57% of patients on omeprazole were free of heartburn (vs. 19% on placebo), 75% were free of regurgitation (47%) and 43% were completely asymptomatic (14%), each with P〈0.0001. Fewer patients in the omeprazole group required alginate/antacid relief medication (P〈0.05). Symptom relief (time to first heartburn-free day) was more rapid with omeprazole (2 vs. 5 days on placebo; P〈0.01). A greater reduction in anxiety occurred in the omeprazole group (P〈0.05). Conclusion: Omeprazole 20 mg once daily is effective in providing relief of the symptoms typical of gastro-oesophageal reflux disease in patients with essentially normal oesophageal mucosa.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0031-9422Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
12Greenberg, R. ; Goldberg, T.E. ; Griffin, S. ; Gold, J.M. ; Kleinman, J.E. ; Pickar, D. ; Weinberger, D.R.
Amsterdam : ElsevierStaff ViewISSN: 0920-9964Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
13Goldberg, T.E. ; Weinberger, D.R. ; Gold, J.M. ; Greenberg, R. ; Griffin, S. ; Schulz, S.C. ; Pickar, D. ; Kleinman, J.E.
Amsterdam : ElsevierStaff ViewISSN: 0920-9964Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
14Cree, R. T. J. ; Warnell, I. ; Staunton, M. ; Shaw, I. ; Bullock, R. ; Griffin, S. M. ; Baudouin, S. V.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The acute respiratory distress syndrome occurs in approximately 10% of all patients undergoing elective oesophagectomy. Local increases in lung pro-inflammatory cytokines have been previously detected in high-risk patients before the development of the acute respiratory distress syndrome. We hypothesised that similar changes would occur following oesophagectomy. Two groups of patients were studied. In the collapsed lung group (n = 11), interelukin-8 and vascular endothelial growth factor were measured in bronchoalveolar lavage samples obtained from the intra-operative collapsed lung after operation. In the ventilated lung group (n = 10), bronchoalveolar lavage was performed after operation from the ventilated lung and cytokines measured. Cytokines were also measured in peripheral blood samples before and after operation. Bronchoalveolar lavage cytokine levels in both lungs were of an order of magnitude greater than in peripheral blood. Pulmonary pro-inflammatory cytokine release occurs following oesphageal surgery and may indicate subclinical lung injury.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1572-9516Source: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract This paper presents the results of optical interferometry experiments in which the phase of photons in one arm of a Mach-Zehnder interferometer is modified by applying a transverse constriction. An equivalent quantum interferometry experiment using neutron de Broglie waves is discussed in which the observed phase shift is in the spirit of the force-free phase shift of the Aharonov-Bohm effects. In the optical experiments the experimental results are in excellent agreement with predictions.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1619-6937Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: Summary The paper presents a theoretical formulation for spherical shells reinforced by meridional and circumferential stiffeners. Active damping of the shell is introduced through control action of piezoelectric coupled pairs bonded to the meridional stiffeners. The induced loads can include radial pressure and a thermal field that are independent of the circumferential coordinate. Neglecting local deformations between adjacent meridional stiffeners, the response of the shell will be axisymmetric. The analysis employs the Donnell-Mushtari-Vlasov version of Love's theory of shells together with a smeared stiffeners technique. The paper also considers a particular case of shell mounted piezoelectic coupled pairs without conventional stiffeners. A closed form solution is derived for spherical panels without conventional stiffeners within the range of the meridional coordinate between 75° and 90° using a version of the Geckeler approximation.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1573-1898Source: Springer Online Journal Archives 1860-2000Topics: Natural Sciences in GeneralNotes: Abstract Water is an important resource. Surprisingly, research into students' conceptions of water has been confined largely to studies of change of state. This paper reports the results of interviews about underground water, water pollution, the water cycle, and change of state). There were 45 students interviewed about these phenomena: all were in Year 9 or Year 10 in Western Australia from three schools, two country, on emetropolitan. In addition, 715 students in Years 9 and 10 in five government schools, three metropolitan and two country, completed a teacher-made, water topic test. Students appear to have a good understanding of some water-related phenomena, such as the water cycle, but have conceptions about other phenomena, such as the water table, which are not in accord with scientific views. As others have reported, interviews reveal that students often use scientific language without understanding.Type of Medium: Electronic ResourceURL: -
18Influence of poly(acrylic acid) molar mass on the fracture properties of glass polyalkenoate cementsStaff View
ISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract The failure behaviour of glass polyalkenoate cements was investigated using a linear elastic fracture mechanics (LEFM) approach. Cements were based on four model glasses with varying reactivity and four poly(acrylic acid)s (PAA)s with number average molar masses (Mn) ranging from 3.25 × 104 to 1.08 × 105. Cement properties were studied at time intervals of one, seven and twenty eight days. Compressive strengths (σc) of the cements increased with increasing fluorine content of the glass, with increased molar mass of the PAA and with ageing time. The Young's moduli increased with time, but were lower for cements based on the fluorine free glass. Moduli values were independant of PAA molar mass. The un-notched fracture strength (σf) of the cement increased with the molar mass of the PAA and with ageing time. Glass composition did not appreciably influence the un-notched fracture strength. The fracture toughness (KIC) increased with the molar mass of the PAA and with ageing time, but reduced with increasing fluorine content of the glass. The toughness (GIC) was dependant on molar mass. The influence of molar mass was not as great as predicted by the reptation chain pull-out model for fracture. The molar mass dependence of toughness was greatest with the lower fluorine content glasses. The plastic zone size at the crack tip increased with the molar mass of the PAA. However the plastic zone size decreased with ageing time for all the cements studied and was smaller for the more reactive higher fluorine content glasses.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0032-3888Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: The objective of this study was to develop mathematical relations for predicting the strength of adhesive-bonded double-lap joints under cantilevered bending. Based on the strength of composite materials theory, two models were proposed to predict the stress-strain distribution and vertical deflection of the laminates and the adhesive under this loading condition. The first model was based on the basic beam theory with the assumption that every cross section in a plane before bending remains plane after the bending load is applied. In the other model, a strain gap between each bonded surface is assumed. Based on the second model and the predicted peel failure mode, the effects of shear modulus of the adhesive, joint length, and adhesive thickness on the joint strength were evaluated. Scotchply composite laminates were used as the adherends of the double-lap joints in the experimental investigation. An Instron machine fitted with a special apparatus was used for conducting the experiments. By the attachment of strain gages to the adherends and through the use of a dial indicator, the theoretical models were verified experimentally.Additional Material: 15 Ill.Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0032-3888Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: A theoretical model is developed to predict the strain of the pipe, coupling, and adhesive under tensile loading of an adhesive bonded joint. The model is found to be within 10 percent of the experimental pipe and coupling strain. Based on the model, several failure modes and their locations are defined and related to the measured data. In this investigation, delamination is the dominating mode of failure. The delamination stress for each test sample is within 7 percent of the average theoretical delamination stress. In addition, the effect of the coupling length, coupling Young's modulus, adhesive shear modulus, and adhesive thickness on the delamination failure are investigated. The model shows that decreasing the modulus of the coupling improves the delamination failure load; however, the coupling strain at the middle of the joint is increased by this variation. Increasing the shear modulus of the adhesive provides the most significant improvement of the joint delamination failure load. Two geometric factors, the joint length and the adhesive thickness also affect the joint failure load. The joint delamination failure load can only be significantly improved by increasing the bonding length up to a certain limit. Increasing the adhesive thickness increases the delamination failure load, however, a large gap between the pipe and coupling may contribute to misalignment during installation which may result in imposed moments under tensile loading. This study can supply the manufacturers with the appropriate design parameters to improve the joint performance significantly under tensile loading.Additional Material: 10 Ill.Type of Medium: Electronic ResourceURL: