Search Results - (Author, Cooperation:S. D. Brown)
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1Latest Papers from Table of Contents or Articles in PressJ. M. Parks ; A. Johs ; M. Podar ; R. Bridou ; R. A. Hurt, Jr. ; S. D. Smith ; S. J. Tomanicek ; Y. Qian ; S. D. Brown ; C. C. Brandt ; A. V. Palumbo ; J. C. Smith ; J. D. Wall ; D. A. Elias ; L. Liang
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-02-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Bacterial Proteins/*genetics ; Corrinoids/genetics ; Desulfovibrio desulfuricans/*genetics/metabolism ; Environmental Pollutants/*metabolism ; Ferredoxins/genetics ; Gene Deletion ; Geobacter/*genetics/metabolism ; Mercury/*metabolism ; Methylation ; Molecular Sequence Data ; *Multigene FamilyPublished by: -
2Latest Papers from Table of Contents or Articles in PressM. H. Jones ; D. Bewsher ; D. S. Brown
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-11-23Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressJ. Barthel, J. Mayer, J. Rusz, P.-L. Ho, X. Y. Zhong, M. Lentzen, R. E. Dunin-Borkowski, K. W. Urban, H. G. Brown, S. D. Findlay, and L. J. Allen
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-04-06Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Structure, structural phase transitions, mechanical properties, defectsPublished by: -
4Latest Papers from Table of Contents or Articles in PressChristensen, G. A., Somenahally, A. C., Moberly, J. G., Miller, C. M., King, A. J., Gilmour, C. C., Brown, S. D., Podar, M., Brandt, C. C., Brooks, S. C., Palumbo, A. V., Wall, J. D., Elias, D. A.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-01-18Publisher: The American Society for Microbiology (ASM)Print ISSN: 0099-2240Electronic ISSN: 1098-5336Topics: BiologyPublished by: -
5Articles: DFG German National LicensesBrown, S. D. ; Street, R. ; Chantrell, R. W. ; Haycock, P. W. ; O'Grady, K.
[S.l.] : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Measurements have been made of the time dependence of magnetization, under constant applied field conditions, of thin films of Tb–Fe–Co alloy. The results have been analyzed using a model in which it is assumed that magnetization proceeds by thermal activation of irreversible switching of the magnetic moments of identical elementary volumes. It is assumed that the activation energy for switching, intrinsically the same for all elementary volumes, varies according to local interactions. Values of the fluctuation field Λ are derived and it is found that for the films examined, Λ is independent of magnetization M and the applied field. It is shown that information about the magnetic interactions between the elementary volumes, due to exchange and demagnetizing fields, may be derived from graphs of dM/dt vs M. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Time dependence of magnetization in ferromagnetic materials was first described towards the end of the 19th century. Subsequently, two types of mechanisms responsible for time dependent behavior were identified and became known as "diffusion'' and "fluctuation'' after-effect or viscosity. The former depends on thermally induced motion of impurity atoms. The latter is a consequence of thermal activation of irreversible domain processes such as domain-wall motion and the nucleation of domains of reverse magnetization. Fluctuation viscosity affects, to a greater or smaller extent, all magnetic materials subject to hysteresis. In the late 1940s descriptions of magnetic viscosity in terms of fluctuation fields (Néel) and activation energy distributions (Street and Woolley) were developed. The two approaches will be described. An analysis of the time dependent phenomena exhibited by magneto-optical films will be presented as a simple example of the application of activation energy modeling.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesBROWN, S. D. M. ; BROWN, K. A. ; SUTCLIFFE, M. J. ; CAVANNA, J. S. ; GREENFIELD, A. J. ; STEEL, K. P.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesChartier, F. L. ; Keer, J. T. ; Sutcliffe, M. J. ; Henriques, D. A. ; Mileham, P. ; Brown, S. D. M.
[s.l.] : Nature Publishing Group
Published 1992Staff ViewISSN: 1546-1718Source: Nature Archives 1869 - 2009Topics: BiologyMedicineNotes: [Auszug] We have constructed a new generation yeast artificial chromosome (YAC) library from female C57BL/10 mice in a recombination–deficient strain of Saccharomyces cerevisiae carrying a mutation in the RAD52 gene. The YAC library contains 41,568 clones with an average insert size of 240 kilobases, ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesGibson, F. ; Walsh, J. ; Mburu, P. ; Varela, A. ; Brown, K. A. ; Antonio, M. ; Beisel, K. W. ; Steel, K. P. ; Brown, S. D. M.
[s.l.] : Nature Publishing Group
Published 1995Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The Olfactory marker protein gene (Omp) is very tightly linked to the mouse shl mutation on mouse chromosome 7 (ref. 8). In a backcross of 1,066 progeny segregating for the shl mutation, Omp is non-recombinant with shl, indicating that the shl locus is likely to lie within 0.1 centimorgan ...Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Analytical equilibrium sedimentation in neutral CsCl of total DNA of M. spretus that is bound to the dye Hoechst 33258 does not reveal a satellite DNA component (Fig. 1b) equivalent to that resolved from the total DNA of M. musculus sedimented in the same conditions (Fig. 1a). Hoechst 33258-CsCl ...Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesBrockdorff, N. ; Cross, G. S. ; Cavanna, J. S. ; Fisher, E. M. C. ; Lyon, M. F. ; Davies, K. E. ; Brown, S. D. M.
[s.l.] : Nature Publishing Group
Published 1987Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] An interspecific Mus domesticus/ Mus spretus cross was initiated for the mapping of molecular markers to the mouse X chromosome (Fig. 1). A female M. domesticus mouse carrying the X-linked coat-texture mutations Harlequin (Hq), Tabby (Ta) and Lined (Li) was crossed to a male M. spretus. Four female ...Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1573-2665Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The mouse mutant resource is a valuable tool for gene function studies in the post-genomics era. However, despite a seemingly large catalogue of mouse mutants, it is recognized that we have access to mutations at only a small fraction of the total number of mouse genes. There is a phenotype gap that needs to be narrowed by the implementation of large-scale, systematic mutagenesis programmes in the mouse. Both genotype-driven and phenotype-driven approaches can be employed to recover new mouse mutations. Genotype-driven approaches include large-scale genome-wide mutagenesis by gene trapping in embryonic stem cells. For genotype-driven approaches, the initial focus is on the characterization of the mutational change to the genome. Identification of the mutated gene is relatively trivial, but the genotype-driven route provides little indication of the likely phenotypic outcome of the mutation. In contrast, phenotype-driven approaches employ mutagenesis procedures that emphasize the recovery of novel phenotypes without prior assumptions about the underlying gene or pathway that has been disrupted – although identifying the underlying gene may not be trivial. One phenotype-driven approach includes chemical mutagenesis using N-ethyl-N-nitrosourea (ENU). ENU mutagenesis programmes are increasingly being brought to bear on increasing the breadth and depth of the mouse mutant resource, and in so doing narrowing the phenotype gap.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1432-0762Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Summary Variation in weight, wing length and bill length in a population of grey-crowned babblers is influenced primarily by sex and age, but correlations with size of social unit, with reproductive success, and with vegetation are also detectable (Table 1). The latter correlations vary with sex, age, and status as helper or breeder. Differential wear according to behavioral role, competition for status, incubation, and inheritance are discussed as possible causal mechanisms. Helpers were not detectably smaller in any dimension than breeders of the same age and sex. Male and female non-breeding helpers differ in patterns of morphological correlation, suggesting that they have different behavioral roles. Breeding males have a unique pattern of morphological correlation, suggesting that their foraging behavior differs from breeding females and non-breeders.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract E-test, broth microdilution, and agar dilution susceptibility tests were used to evaluate penicillin and five extended-spectrum cephalosporins against 196 strains ofStreptococcus pneumoniae with different levels of penicillin resistance. Oxacillin disk tests corresponded to minimum inhibitory concentrations of penicillin determined by the E-test better than those generated by broth microdilution or agar dilution methods. Relative potency of the study drugs was as follows: cefotaxime=ceftriaxone 〉 penicillin 〉 cefuroxime 〉 ceftizoxime 〉 ceftazidime.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Moxifloxacin (Bay 12–8039), ciprofloxacin, and levofloxacin were compared in vitro against 1074 clinical isolates gathered from different medical centers throughout North America during the winter months of 1997. Moxifloxacin E tests and broth microdilution tests gave comparable results. Moxifloxacin was particularly potent against respiratory pathogens such as Haemophilus influenzae and Streptococcus pneumoniae. Ciprofloxacin was the most potent study drug against the family of Enterobacteriaceae and Pseudomonas spp. For tests of 5 μg moxifloxacin disks, zone size criteria of ≤17 mm for resistant (MIC ≥8 μg/ml) and ≥21 mm for susceptible (MIC ≤2 μg/ml) are provisionally proposed for use while clinical trials are under way.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract In vitro susceptibility tests were performed with 350 selected strains ofStreptococcus pneumoniae to evaluate disk diffusion tests with 30 μg and 1 μg cefotaxime disks. Zones were compared to MICs of cefotaxime with and without its desacetyl metabolite. Cefotaxime was two to eight times more active than desacetyl cefotaxime, but the two compounds were additive when combined in vitro. For 30 μg disks, zone size breakpoints were ≤27 mm, 28–30 mm and ≥31 mm for resistant, intermediate and susceptible, respectively. For 1 μg disks, those zone size criteria were reduced to ≤13 mm, 14–16 mm and ≥17 mm. The 30 μg disk that is currently available for testing other species can be used for testing pneumococci; however, the 1 μg disk has some important advantages.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The purpose of this study was to compare the in vitro activity of a new ketolide, HMR 3004 (RU64004), to that of three macrolides and one azalide against 608 Streptococcus pneumoniae and 202 Haemophilus influenzae. Macrolide-resistant pneumococci were susceptible to HMR 3004, even if they were resistant to clindamycin. Against Haemophilus influenzae, HMR 3004 and azithromycin were nearly identical in potency; the macrolides were 8- to 16-fold less active. HMR 3004 may be useful for treating respiratory tract infections if sufficient concentrations can be achieved at the local sites of infection.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1435-4373Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Multiple studies were performed to define the quality control ranges for susceptibility tests of fosfomycin tromethamine. For disk diffusion tests, the limits proposed are 22 to 30 mm forEscherichia coli ATCC 25922 and 25 to 33 mm forStaphylococcus aureus ATCC 25923. Broth microdilution tests were not reproducible. For agar dilution tests, ranges proposed are 0.5 to 2.0 μg/ml forEscherichia coli ATCC 25922, 0.5 to 4.0 μg/ml forStaphylococcus aureus ATCC 29213; 2.0 to 8.0 μg/ml forPseudomonas aeruginosa ATCC 27853, and 32 to 128 μg/ml forEnterococcus faecalis ATCC 29212.Type of Medium: Electronic ResourceURL: