Search Results - (Author, Cooperation:S. D. Bentley)
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1N. J. Croucher ; S. R. Harris ; C. Fraser ; M. A. Quail ; J. Burton ; M. van der Linden ; L. McGee ; A. von Gottberg ; J. H. Song ; K. S. Ko ; B. Pichon ; S. Baker ; C. M. Parry ; L. M. Lambertsen ; D. Shahinas ; D. R. Pillai ; T. J. Mitchell ; G. Dougan ; A. Tomasz ; K. P. Klugman ; J. Parkhill ; W. P. Hanage ; S. D. Bentley
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-01-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological ; Anti-Bacterial Agents/pharmacology ; Antigenic Variation ; DNA Transposable Elements ; Drug Resistance, Multiple, Bacterial ; *Evolution, Molecular ; Genome, Bacterial ; Humans ; Molecular Epidemiology ; Phylogeny ; Phylogeography ; Pneumococcal Infections/drug therapy/*microbiology ; Pneumococcal Vaccines/immunology ; Polymorphism, Single Nucleotide ; Prophages/genetics ; *Recombination, Genetic ; Selection, Genetic ; Serotyping ; Streptococcus Phages/genetics ; Streptococcus pneumoniae/classification/drug effects/*genetics/immunologyPublished by: -
2Bentley, S. D. ; Brown, S. ; Murphy, L. D. ; Harris, D. E. ; Quail, M. A. ; Parkhill, J. ; Barrell, B. G. ; McCormick, J. R. ; Santamaria, R. I. ; Losick, R. ; Yamasaki, M. ; Kinashi, H. ; Chen, C. W. ; Chandra, G. ; Jakimowicz, D. ; Kieser, H. M. ; Kieser, T. ; Chater, K. F.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2958Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: The sequencing of the entire genetic complement of Streptomyces coelicolor A3(2) has been completed with the determination of the 365 023 bp sequence of the linear plasmid SCP1. Remarkably, the functional distribution of SCP1 genes somewhat resembles that of the chromosome: predicted gene products/functions include ECF sigma factors, antibiotic biosynthesis, a gamma-butyrolactone signalling system, members of the actinomycete-specific Wbl class of regulatory proteins and 14 secreted proteins. Some of these genes are among the 18 that contain a TTA codon, making them targets for the developmentally important tRNA encoded by the bldA gene. RNA analysis and gene fusions showed that one of the TTA-containing genes is part of a large bldA-dependent operon, the gene products of which include three proteins isolated from the spore surface by detergent washing (SapC, D and E), and several probable metabolic enzymes. SCP1 shows much evidence of recombinational interactions with other replicons and transposable elements during its history. For example, it has two sets of partitioning genes (which may explain why an integrated copy of SCP1 partially suppressed the defective partitioning of a parAB-deleted chromosome during sporulation). SCP1 carries a cluster of probable transfer determinants and genes encoding likely DNA polymerase III subunits, but it lacks an obvious candidate gene for the terminal protein associated with its ends. This may be related to atypical features of its end sequences.Type of Medium: Electronic ResourceURL: -
3James, K. D. ; Thomson, N. R. ; Pickard, D. ; Wain, J. ; Churcher, C. ; Mungall, K. L. ; Bentley, S. D. ; Holden, M. T. G. ; Sebaihia, M. ; Baker, S. ; Basham, D. ; Brooks, K. ; Chillingworth, T. ; Connerton, P. ; Cronin, A. ; Davis, P. ; Davies, R. M. ; Dowd, L. ; White, N. ; Farrar, J. ; Feltwell, T. ; Hamlin, N. ; Haque, A. ; Hien, T. T. ; Holroyd, S.
[s.l.] : Macmillian Magazines Ltd.
Published 2001Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Salmonella enterica serovar Typhi (S. typhi) is the aetiological agent of typhoid fever, a serious invasive bacterial disease of humans with an annual global burden of approximately 16 million cases, leading to 600,000 fatalities. Many S. enterica serovars actively invade the mucosal surface of ...Type of Medium: Electronic ResourceURL: -
4Wren, B. W. ; Thomson, N. R. ; Titball, R. W. ; Holden, M. T. G. ; Prentice, M. B. ; Sebaihia, M. ; James, K. D. ; Churcher, C. ; Mungall, K. L. ; Baker, S. ; Basham, D. ; Bentley, S. D. ; Brooks, K. ; Cerdeño-Tárraga, A. M. ; Chillingworth, T. ; Cronin, A. ; Davies, R. M. ; Davis, P. ; Dougan, G. ; Feltwell, T. ; Hamlin, N. ; Holroyd, S. ; Jagels, K. ; Karlyshev, A. V. ; Leather, S.
[s.l.] : Macmillian Magazines Ltd.
Published 2001Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The Gram-negative bacterium Yersinia pestis is the causative agent of the systemic invasive infectious disease classically referred to as plague, and has been responsible for three human pandemics: the Justinian plague (sixth to eighth centuries), the Black Death (fourteenth to nineteenth ...Type of Medium: Electronic ResourceURL: -
5Achtman, M. ; James, K. D. ; Bentley, S. D. ; Churcher, C. ; Klee, S. R. ; Morelli, G. ; Basham, D. ; Brown, D. ; Chillingworth, T. ; Davies, R. M. ; Davis, P. ; Devlin, K. ; Feltwell, T. ; Hamlin, N. ; Holroyd, S. ; Jagels, K. ; Leather, S. ; Moule, S. ; Mungall, K. ; Quail, M. A. ; Rajandream, M.-A. ; Rutherford, K. M. ; Simmonds, M. ; Skelton, J. ; Whitehead, S.
[s.l.] : Macmillian Magazines Ltd.
Published 2000Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Neisseria meningitidis causes bacterial meningitis and is therefore responsible for considerable morbidity and mortality in both the developed and the developing world. Meningococci are opportunistic pathogens that colonize the nasopharynges and oropharynges of asymptomatic carriers. For ...Type of Medium: Electronic ResourceURL: