Search Results - (Author, Cooperation:S. C. Lee)
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1Staff View
Publication Date: 2018-01-25Publisher: BMJ Publishing GroupPrint ISSN: 0022-2593Electronic ISSN: 1468-6244Topics: MedicineKeywords: Open accessPublished by: -
2Formenti, S. C., Lee, P., Adams, S., Goldberg, J. D., Li, X., Xie, M. W., Ratikan, J. A., Felix, C., Hwang, L., Faull, K. F., Sayre, J. W., Hurvitz, S., Glaspy, J. A., Comin-Anduix, B., Demaria, S., Schaue, D., McBride, W. H.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-06-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3S. Calo ; C. Shertz-Wall ; S. C. Lee ; R. J. Bastidas ; F. E. Nicolas ; J. A. Granek ; P. Mieczkowski ; S. Torres-Martinez ; R. M. Ruiz-Vazquez ; M. E. Cardenas ; J. Heitman
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-08-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Calcineurin/genetics/metabolism ; Calcineurin Inhibitors ; Drug Resistance, Fungal/*genetics ; Epigenesis, Genetic/*genetics ; Humans ; Hyphae/drug effects/genetics/growth & development ; Molecular Sequence Data ; Mucor/*drug effects/*genetics/growth & development ; Mucormycosis/drug therapy/microbiology ; Mutation/*genetics ; Phenotype ; *RNA Interference ; Tacrolimus/metabolism/*pharmacology ; Tacrolimus Binding Protein 1A/deficiency/genetics/metabolismPublished by: -
4D. Ramanan ; R. Bowcutt ; S. C. Lee ; M. S. Tang ; Z. D. Kurtz ; Y. Ding ; K. Honda ; W. C. Gause ; M. J. Blaser ; R. A. Bonneau ; Y. A. Lim ; P. Loke ; K. Cadwell
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-04-16Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bacteroides/*immunology ; Bacteroides Infections/*immunology ; Clostridiales/immunology ; Clostridium Infections/immunology ; Crohn Disease/*genetics/immunology ; Gastrointestinal Microbiome/*immunology ; Genetic Predisposition to Disease ; Hygiene Hypothesis ; Intestines/*immunology/microbiology/parasitology ; Mice ; Mice, Mutant Strains ; Nod2 Signaling Adaptor Protein/*genetics ; Trichuriasis/*immunology ; Trichuris/*immunologyPublished by: -
5M. Amani ; D. H. Lien ; D. Kiriya ; J. Xiao ; A. Azcatl ; J. Noh ; S. R. Madhvapathy ; R. Addou ; S. Kc ; M. Dubey ; K. Cho ; R. M. Wallace ; S. C. Lee ; J. H. He ; J. W. Ager, 3rd ; X. Zhang ; E. Yablonovitch ; A. Javey
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-11-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
6C. Y. Fong ; O. Gilan ; E. Y. Lam ; A. F. Rubin ; S. Ftouni ; D. Tyler ; K. Stanley ; D. Sinha ; P. Yeh ; J. Morison ; G. Giotopoulos ; D. Lugo ; P. Jeffrey ; S. C. Lee ; C. Carpenter ; R. Gregory ; R. G. Ramsay ; S. W. Lane ; O. Abdel-Wahab ; T. Kouzarides ; R. W. Johnstone ; S. J. Dawson ; B. J. Huntly ; R. K. Prinjha ; A. T. Papenfuss ; M. A. Dawson
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-09-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Azepines/pharmacology ; Benzodiazepines/*pharmacology ; Cell Line, Tumor ; Cells, Cultured ; Chromatin/metabolism ; Clone Cells/drug effects/metabolism/pathology ; Drug Resistance, Neoplasm/*drug effects/genetics ; Epigenesis, Genetic ; Gene Expression Regulation, Neoplastic/drug effects ; Genes, myc/genetics ; Hematopoietic Stem Cells/cytology/drug effects/metabolism ; Humans ; Leukemia, Myeloid, Acute/*drug therapy/genetics/*metabolism/pathology ; Mice ; Molecular Targeted Therapy ; Neoplastic Stem Cells/*drug effects/metabolism/*pathology ; Nuclear Proteins/*antagonists & inhibitors/metabolism ; Transcription Factors/*antagonists & inhibitors/metabolism ; Transcription, Genetic/drug effects ; Triazoles/pharmacology ; Wnt Signaling Pathway/drug effects ; beta Catenin/metabolismPublished by: -
7D. J. Gibbs ; S. C. Lee ; N. M. Isa ; S. Gramuglia ; T. Fukao ; G. W. Bassel ; C. S. Correia ; F. Corbineau ; F. L. Theodoulou ; J. Bailey-Serres ; M. J. Holdsworth
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-10-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acclimatization ; Anaerobiosis/drug effects/genetics ; Arabidopsis/drug effects/genetics/*metabolism ; Arabidopsis Proteins/metabolism ; *Cell Hypoxia/drug effects/genetics ; Ethylenes/pharmacology ; Floods ; Gene Expression Regulation, Plant/drug effects ; *Homeostasis/drug effects ; Immersion ; Oryza/drug effects/metabolism ; Oxygen/metabolism/pharmacology ; Proteolysis/drug effects ; RNA, Messenger/genetics/metabolism ; RNA, Plant/genetics/metabolism ; Transcription Factors/metabolismPublished by: -
8A. E. Hochreiter-Hufford ; C. S. Lee ; J. M. Kinchen ; J. D. Sokolowski ; S. Arandjelovic ; J. A. Call ; A. L. Klibanov ; Z. Yan ; J. W. Mandell ; K. S. Ravichandran
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-04-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Angiogenic Proteins/deficiency/genetics/*metabolism ; Animals ; Apoptosis/drug effects/*physiology ; Cell Communication ; Cell Differentiation ; *Cell Fusion ; Cell Line ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Muscle Development ; Muscle Fibers, Skeletal/cytology/metabolism/pathology ; Muscle, Skeletal/*cytology/metabolism ; Myoblasts/*cytology/metabolism ; Phosphatidylserines/metabolism ; Receptors, Cell Surface/deficiency/genetics/*metabolism ; *Signal TransductionPublished by: -
9M. Kretz ; Z. Siprashvili ; C. Chu ; D. E. Webster ; A. Zehnder ; K. Qu ; C. S. Lee ; R. J. Flockhart ; A. F. Groff ; J. Chow ; D. Johnston ; G. E. Kim ; R. C. Spitale ; R. A. Flynn ; G. X. Zheng ; S. Aiyer ; A. Raj ; J. L. Rinn ; H. Y. Chang ; P. A. Khavari
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Cell Differentiation/*genetics ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Epidermis/*cytology/*metabolism ; Gene Expression Regulation ; High-Throughput Screening Assays ; Humans ; Keratinocytes ; Mutation ; Nucleotide Motifs/genetics ; Protein Binding ; RNA Stability/genetics ; RNA, Long Noncoding/*genetics/*metabolism ; RNA, Messenger/genetics/metabolism ; RNA-Binding Proteins/metabolism ; Skin Diseases/geneticsPublished by: -
10N. A. Naryshkin ; M. Weetall ; A. Dakka ; J. Narasimhan ; X. Zhao ; Z. Feng ; K. K. Ling ; G. M. Karp ; H. Qi ; M. G. Woll ; G. Chen ; N. Zhang ; V. Gabbeta ; P. Vazirani ; A. Bhattacharyya ; B. Furia ; N. Risher ; J. Sheedy ; R. Kong ; J. Ma ; A. Turpoff ; C. S. Lee ; X. Zhang ; Y. C. Moon ; P. Trifillis ; E. M. Welch ; J. M. Colacino ; J. Babiak ; N. G. Almstead ; S. W. Peltz ; L. A. Eng ; K. S. Chen ; J. L. Mull ; M. S. Lynes ; L. L. Rubin ; P. Fontoura ; L. Santarelli ; D. Haehnke ; K. D. McCarthy ; R. Schmucki ; M. Ebeling ; M. Sivaramakrishnan ; C. P. Ko ; S. V. Paushkin ; H. Ratni ; I. Gerlach ; A. Ghosh ; F. Metzger
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-08-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Administration, Oral ; Alternative Splicing/*drug effects ; Animals ; Cells, Cultured ; Coumarins/*administration & dosage/chemistry ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Humans ; Isocoumarins/*administration & dosage/chemistry ; Longevity/*drug effects ; Mice ; Muscular Atrophy, Spinal/*drug therapy/genetics/metabolism ; Pyrimidinones/*administration & dosage/chemistry ; RNA, Messenger/genetics ; Sequence Deletion ; Small Molecule Libraries/*administration & dosage/chemistry ; Survival of Motor Neuron 2 Protein/*genetics/metabolismPublished by: -
11Rajan, P. I., Vijaya, J. J., Jesudoss, S. K., Kaviyarasu, K., Lee, S.-C., Kennedy, L. J., Jothiramalingam, R., Al-Lohedan, H. A., Abdullah, M. M. S.
Royal Society
Published 2018Staff ViewPublication Date: 2018-06-21Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: nanotechnology, computational chemistry, green chemistryPublished by: -
12Iyyappa Rajan, P., Judith Vijaya, J., Jesudoss, S. K., Kaviyarasu, K., Lee, S.-C., John Kennedy, L., Jothiramalingam, R., Al-Lohedan, H. A., Mahamad Abdullah, M.
Royal Society
Published 2018Staff ViewPublication Date: 2018-03-14Publisher: Royal SocietyElectronic ISSN: 2054-5703Topics: Natural Sciences in GeneralKeywords: nanotechnology, computational chemistry, green chemistryPublished by: -
13Pantel, A. R., Ackerman, D., Lee, S.-C., Mankoff, D. A., Gade, T. P.
The Society of Nuclear Medicine (SNM)
Published 2018Staff ViewPublication Date: 2018-09-05Publisher: The Society of Nuclear Medicine (SNM)Print ISSN: 0022-3123Topics: MedicinePublished by: -
14Staff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The time-dependent formulation of Raman scattering is used to derive simple expressions for fundamental and overtone intensities that depend on potential energy features in the Franck–Condon region and the homogeneous damping constant due to the bath modes. From the Raman excitation profiles, the dependence of the full width at half-maximum on the damping constant is calculated. The results are applied to the rich resonance Raman spectra and Raman excitation profiles of transition metal complexes, in particular, Cs3[Re2OCl10] and Cs4[W2OCl10], to determine the magnitude of the geometric changes occurring upon excitation of the molecule from the ground to the excited electronic state. For each compound, the multidimensional harmonic potential surface and damping constant derived for the excited electronic state are then used to simulate the observed Raman excitation profiles and resonance Raman spectrum.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: An accurate, back-of-the-envelope spectral moment method is described to obtain molecular parameters of excited state molecules and ions from vibrationally resolved absorption spectra. Since it is not an iterative procedure, the spectral moment method is clearly much faster than the least-squares Franck–Condon analysis for obtaining molecular parameters, and the procedure described here can even be implemented on a hand-held calculator. Some of the drawbacks of Franck–Condon analysis are overcome by the spectral moment method. Comparison of molecular parameters for a diverse range of excited state molecules and ions obtained by the spectral moment method versus Franck–Condon analysis or rotational spectroscopy reveal the high accuracy of the procedure here. Simulations of vibrationally resolved absorption spectra show that the spectral moment method with the Morse potential approximation gives an envelope that matches very well the observed spectra.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1089-7658Source: AIP Digital ArchiveTopics: MathematicsPhysicsNotes: The field equations for axially symmetric gravitational fields in 4+K dimensions with K-dimensional toroidal compatification can be reduced to those of a generalized nonlinear sigma model. The dual symmetry of this model is considered first. Then the soliton transformations for these equations are derived using the method of Belinskii and Zakharov consequently generalizing their results to the higher-dimensional case. From the result of one-soliton transformation, a series of discrete symmetries generalizing the Neugebauer–Kramer transformation in the four-dimensional case are obtained. The basic properties of these new transformations are studied.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1089-7658Source: AIP Digital ArchiveTopics: MathematicsPhysicsNotes: The solutions of vacuum Einstein equations in 4+K dimensions with 2+K commuting Killing vectors under the Abelian Kaluza–Klein ansatz are considered. This system admits Belinskii–Zakharov-type soliton transformations. The explicit formulas for general N-soliton transformations are obtained by iterating the formulas for one-soliton transformation.Type of Medium: Electronic ResourceURL: -
18Lee, S. C. ; Stintz, A. ; Brueck, S. R. J.
[S.l.] : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Growth of InAs islands on a GaAs(001) substrate patterned with ∼50–200-nm diameter holes in an SiO2 mask overlayer providing selective GaAs nucleation areas is reported. The nanoscale pattern was generated in the SiO2 film by large-area interferometric lithography and dry etching. Two-dimensional, 285-nm period, arrays of InAs islands having heights of 10–15 nm with three different bottom diameters of 50–100, ∼150, and ∼200 nm were selectively grown on SiO2 patterned substrates by molecular beam epitaxy. Growth conditions were chosen to provide a very-low sticking coefficient of In atoms on the SiO2 surface suppressing volume contribution from migration of In atoms incident on the SiO2 mask region to nearby open GaAs surface areas. Formation of spherical-section InAs dots with diameters of about 50 nm relying on nanoscale-limited area growth is demonstrated. As the diameter of the hole increases beyond 150 nm, InAs islands deviate from a spherical section and self-assembled quantum dots confined within the open GaAs surface appear. A relation between dot formation and the nanoscale growth area is proposed, with a transition from single- to multiple-dot formation occurring at hole diameters of ∼100–150 nm. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
19Lee, S-C. ; Lee, J-W. ; Jung, J.E. ; Lee, H-W. ; Chun, S.D. ; Kang, I.K. ; Won, Y.H. ; Kim, Y.P.
Oxford, UK : Blackwell Science Ltd
Published 2000Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Ultraviolet (UV) irradiation is known to induce serious oxidative damage in the skin via lipid peroxidation. Nitric oxide (NO) synthesized by keratinocytes, melanocytes and endothelial cells in response to proinflammatory cytokines and UV radiation, has been reported to prevent UV-induced apoptosis in the skin. We have examined the effects of NO on UVB-induced lipid peroxidation in murine skin in vivo. UVB induced a dose-dependent increase in lipid peroxidation of skin extracts in vitro; however, lipid peroxidation in the skin in vivo remained unaffected at irradiation doses of less than 1·0 J cm−2 and decreased significantly at doses over 1·5 J cm−2 (P 〈 0·01). Time-delayed inhibition of lipid peroxidation in the skin in vivo was observed after irradiation at 1·5 J cm−2. Administration of N G-nitro- l-arginine methyl ester ( L-NAME), an inhibitor of NO synthesis, enhanced lipid peroxidation (P 〈 0·05), while it suppressed the ear-swelling response (ESR), a biological marker of inflammation. By contrast, administration of sodium nitroprusside, an NO enhancer, suppressed lipid peroxidation (P 〈 0·01), while it enhanced the ESR. Expression of inducible nitric oxide synthase (iNOS) was observed from 12 to 48 h postirradiation at doses of 0·4–1·6 J cm−2. The UVB-induced iNOS expression was markedly inhibited by L-NAME, suggesting that iNOS is a major enzyme in the production of NO. These results suggest that NO acts as a mediator of the inflammatory response in UVB-irradiated skin, and that lipid peroxidation is inversely regulated with the NO-mediated inflammatory response in vivo.Type of Medium: Electronic ResourceURL: -
20Chen, Y. F. ; Shen, J. L. ; Chang, I. M. ; Chang, S. Z. ; Lee, S. C.
[S.l.] : American Institute of Physics (AIP)
Published 1995Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Photoluminescence measurement is used to study the properties of In0.53Ga0.47As epilayers grown on InP-coated GaAs substrates. Several structures are designed to test the qualities of the epilayers. It is shown that device-quality In0.53Ga0.47As on a GaAs substrate can be achieved. The effects of hydrogenation using a photochemical-vapor-deposition system are studied, and an enhancement of the band-edge luminescence intensity by a factor of 4 is observed. The resulting intensity even exceeds that of the film grown directly on a lattice-matched InP substrate. In addition, the emission coming from lattice defects is greatly reduced after hydrogenation. These results not only further support the potential application of using binary buffer layer concepts in large lattice-mismatched systems, but also demonstrate that the photochemical-vapor-deposition system is a useful tool for injecting hydrogen into InGaAs epilayers. © 1995 American Institute of Physics.Type of Medium: Electronic ResourceURL: