Search Results - (Author, Cooperation:S. Botha)
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1T. R. Barends ; L. Foucar ; S. Botha ; R. B. Doak ; R. L. Shoeman ; K. Nass ; J. E. Koglin ; G. J. Williams ; S. Boutet ; M. Messerschmidt ; I. Schlichting
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-26Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Chickens ; Crystallization ; Crystallography/*methods ; *Electrons ; Female ; Gadolinium ; *Lasers ; Membrane Proteins/chemistry ; Models, Molecular ; Monte Carlo Method ; Muramidase/chemistry ; Protein Conformation ; Proteins/*chemistry ; Time Factors ; X-Ray Diffraction/*methods ; *X-RaysPublished by: -
2T. R. Barends ; L. Foucar ; A. Ardevol ; K. Nass ; A. Aquila ; S. Botha ; R. B. Doak ; K. Falahati ; E. Hartmann ; M. Hilpert ; M. Heinz ; M. C. Hoffmann ; J. Kofinger ; J. E. Koglin ; G. Kovacsova ; M. Liang ; D. Milathianaki ; H. T. Lemke ; J. Reinstein ; C. M. Roome ; R. L. Shoeman ; G. J. Williams ; I. Burghardt ; G. Hummer ; S. Boutet ; I. Schlichting
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-09-12Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Staff View
ISSN: 1572-8854Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesPhysicsNotes: Abstract The X-ray crystal structure of the drug N-(2,6-dioxo-3-piperidyl)pthalimide (thalidomide), C13H10N2O4, obtained from 1∶1 dimethyformamide-ethanol solution, is reported. This species is monoclinic, space groupC2/c, witha=20.679(5),b=8.042(2),c=14.162(5) Å, β=102.86(3)°,Z=8,R=0.051 for 1674 unique reflections. crystal packing is determined by intermolecular N−H... O hydrogen bonding which is more extensive than that reported in the literature for a racemate of thalidomide crystallizing in space groupP21/n. Comparison of the melting behavior and X-ray powder diffractograms of the two racemic polymorphs shows that they are distinctly different, allowing easy identification of these species. By comparing experimental X-ray powder patterns with those calculated from single crystal data, it was concluded that neither of these polymorphs undergoes a phase change on trituration.Type of Medium: Electronic ResourceURL: