Search Results - (Author, Cooperation:S. Botha)

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  1. 1
    Staff View
    Publication Date:
    2013-11-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Chickens ; Crystallization ; Crystallography/*methods ; *Electrons ; Female ; Gadolinium ; *Lasers ; Membrane Proteins/chemistry ; Models, Molecular ; Monte Carlo Method ; Muramidase/chemistry ; Protein Conformation ; Proteins/*chemistry ; Time Factors ; X-Ray Diffraction/*methods ; *X-Rays
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-09-12
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Caira, M. R. ; Botha, S. A. ; Flanagan, D. R.
    Springer
    Published 1994
    Staff View
    ISSN:
    1572-8854
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Geosciences
    Physics
    Notes:
    Abstract The X-ray crystal structure of the drug N-(2,6-dioxo-3-piperidyl)pthalimide (thalidomide), C13H10N2O4, obtained from 1∶1 dimethyformamide-ethanol solution, is reported. This species is monoclinic, space groupC2/c, witha=20.679(5),b=8.042(2),c=14.162(5) Å, β=102.86(3)°,Z=8,R=0.051 for 1674 unique reflections. crystal packing is determined by intermolecular N−H... O hydrogen bonding which is more extensive than that reported in the literature for a racemate of thalidomide crystallizing in space groupP21/n. Comparison of the melting behavior and X-ray powder diffractograms of the two racemic polymorphs shows that they are distinctly different, allowing easy identification of these species. By comparing experimental X-ray powder patterns with those calculated from single crystal data, it was concluded that neither of these polymorphs undergoes a phase change on trituration.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses