Search Results - (Author, Cooperation:S. Abe)

2018-06-08

Institute of Physics (IOP)

1367-2630

Physics

2018-05-23

Institute of Physics Publishing (IOP)

1748-0221

Physics

2014-10-03

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Cell Separation ; *Cell Transplantation ; Cytokine Receptor Common beta Subunit/deficiency/*genetics ; Female ; *Genetic Therapy ; Lung/*cytology/metabolism/pathology ; Macrophages, Alveolar/*metabolism/*transplantation ; Male ; Mice ; Oligonucleotide Array Sequence Analysis ; Phenotype ; Pulmonary Alveolar Proteinosis/genetics/pathology/*therapy ; Time Factors

1089-7550

AIP Digital Archive

Physics

The structural and magnetic properties of (R,Zr)(Fe,Co)10(R=Nd,Sm) prepared by the rapid-quenching method have been investigated. The presence of zirconium makes it possible to realize a TbCu7-type crystal structure with a high c/a ratio of more than 0.87, while the same crystal structure has a c/a ratio of just 0.84–0.85 in the zirconium-free case. The saturation magnetization of crystals having such a high c/a ratio as 0.87 exceeds 1.7 T at room temperature. These materials can be nitrogenated, and remarkable enhancement of magnetocrystalline anisotropy by nitrogenation can be seen in the case of Sm. The magnetic hardening of these nitrogenated materials can be achieved by annealing before nitrogenation. The highest value of (BH)max obtained so far for the nitrogenated materials is 144 kJ/m3 (18.0 MGOe). The iHc and Br values for this sample are 503 kA/m (6.3 kOe) and 1.08 T, respectively. © 1996 American Institute of Physics.

Electronic Resource

1745-4522

Blackwell Publishing Journal Backfiles 1879-2005

Process Engineering, Biotechnology, Nutrition Technology

Phenolic compounds were extracted with 80% methanol from caryopses and embryos of wheat (cv. Alba and Elena). In extracts the content of total phenolics was determined and UV spectra recorded. For all extracts the antioxidant activity in a β-carotene-linoleate model system, scavenging effect on DPPH radical, and reducing power were examined. Extracts of wheat embryos were characterized by a higher content of total phenolics. UV spectra of phenolic compounds extracted from wheat caryopses were characterized by maxima close to 320 nm due to phenolic acids, and by maxima at shorter wavelengths (272–280 nm) attributed to other phenolic compounds. The antioxidant activities of extracts from caryopses in a β-carotene-linoleate model system were higher than those from embryos. The results so obtained were similar to those observed previously for extracts of rye and triticale grains and leguminous seeds. The scavenging effect of wheat extracts on DPPH radical and their reduction power were weak, but those for embryos extracts were somewhat stronger.

Electronic Resource

0020-1693

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

0003-2670

Acyclic Schiff base ; Copper ; Liquid-liquid extraction ; Macrocyclic Schiff base ; Manganese ; Schiff bases

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

1399-3054

Blackwell Publishing Journal Backfiles 1879-2005

Biology

Polyphenylalamine synthesis by cytoplasmic ribosomes of Gateway barley (Hordeum vulgare) and its virescens single gene nuclear mutant was compared. The cytoplasmic 80S ribosomes were isolated from unimbibed embryo material and the ribosomes were dissociated into their component 60S and 40S subunits by centrifugation through sucrose gradients containing high KCl-to-MgCl2 buffer. These separated subunits could be reassociated by resuspension in buffer having about equimolar concentrations of MgCl2 and KCl. Both homologous and heterologous combinations of the subunits reassociated to give monomeric 80S ribosomes, and the derived monomers as well as various combinations of the individual subunits showed equivalent activity in an in vitro system for poly (U)-directed polyphenylalanine synthesis.

Electronic Resource

1439-0264

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Functional maturation of muscles is related to the constitutional proportion of muscle protein isoforms during development and growth. Although the mouse masseter muscle (MS) is classified as a fast limb muscle, its functions are different from those of a limb muscle. This study investigated the differentiation of myosin heavy chain (MHC) isoforms during the postnatal development periods in mouse MS and mouse tibialis anterior (TA), which is a fast limb muscle. Many anti-MHC slow-type-positive fibres were observed in neonatal MS and TA; these fibres decreased during development. Adult MS was composed of anti-MHC fast-type-positive fibres. MHC isoforms in MS were composed of MHC-2a and MHC-2d soon after birth. MHC-2b was expressed, but MHC-2a was not seen after 21 days. Expression of MHC-2b agreed with the weaning period, that is 2–3 weeks after birth. This fact suggested that the transformation from suckling to mastication changed the MHC isoforms during this period. In this study, the expressions of MHC-2b agree with the weaning period.

Electronic Resource

1439-0264

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Recent studies on the cytoskeleton of osteoblasts have been made mainly using cultured cells. However, the morphology of cultured cells may be altered during subculture. Therefore, cytoskeletal changes of calvarial osteoblasts were investigated in situ by electron microscopy using the detergent perfusion method to preserve cell morphology as well as selectively observing the cytoskeleton in the presence of a high concentration of prostaglandin E2 (PGE2) in the calvarial periphery in rats. Rats were perfused with a mixture of Triton X-100 and glutaraldehyde, then the cytoskeleton was observed by transmission electron microscopy. In osteoblasts of the control group, thick bundles of microfilaments ran parallel to the long axis of the cells immediately below the cell membrane adjacent to the osteoid layer. In contrast, in the osteoblasts of the PGE2-administered group, the external morphology was changed to an asteroid or cubic shape, and thick bundles of microfilaments immediately below the cell membrane adjacent to the osteoid were not observed, although microfilament fibres, with a diameter of 5–6 nm, were observed in the cytoplasm.

Electronic Resource

1439-0264

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Masticatory muscles that are derived from the branchial arches express different compositions of myosin heavy chain (MHC) isoforms during the transitional phase from suckling to mastication. To clarify the developmental changes of murine masseter muscle, the composition of MHC isoforms was examined using immunohistochemical staining and competitive reverse transcription PCR. We found that MHC1 was expressed transiently in the pre and post-natal stages. In the compositional change of isoforms, the embryonic type MHCp was expressed consistently, whereas the adult isoforms increased with the developmental process. In particular, a significant change was observed between embryonic days 14 and 16, a stage when murine facial development is conspicuous. This suggests that the development of murine masseter muscle is closely associated with facial development.

Electronic Resource

1365-2036

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Background : A decrease in pepsinogen and gastrin levels 1–3 months after Helicobacter pylori eradication is well known. However, few data are available on the long-term progression of these decreases beyond 1 year after eradication, and there has been no investigation into whether pepsinogen and gastrin levels return to normal levels as defined by data from H. pylori-negative patients with dyspepsia.Aim : We studied the effect of H. pylori eradication on pepsinogen and gastrin levels for more than 1 year, and compared levels to those in H. pylori-negative patients with dyspepsia. We also investigated the effect of H. pylori eradication on the course of atrophic corpus gastritis as reflected by histology, and on PGI levels and PG I/II ratio.Methods : We enrolled 172 H. pylori-positive patients with dyspepsia who had undergone successful eradication therapy of more than 1 year's duration and 101 non-treated H. pylori-negative patients with dyspepsia. H. pylori status was assessed at entry and at each endoscopy after eradication by culture, histological results, the rapid urease test and the urea breath test. In both groups, patients were evaluated for fasting serum pepsinogen I and II and gastrin using a radioimmunoassay technique, and underwent detailed histological assessment according to the updated Sydney System.Results : In the H. pylori-negative patients, mean serum pepsinogen I and II, I/II ratio and gastrin levels were 52.6 ± 20.8 ng/mL, 9.2 ± 4.2 ng/mL, 6.0 ± 1.7 and 53.5 ± 29.2 pg/mL, respectively. In H. pylori-positive patients with long-term eradication, pepsinogen I and II, I/II ratio and gastrin levels were 81.3 ± 46.6 ng/mL, 25.9 ± 17.1 ng/mL, 3.4 ± 1.3 and 131.9 ± 130.8 pg/mL, respectively, before treatment. At 1–3 months after eradication, serum pepsinogen I and II levels in the H. pylori-positive patients decreased to levels similar to those in the negative patients, whereas pepsinogen I/II ratio and gastrin levels remained lower and higher, respectively, than in the negative patients. Serum pepsinogen I/II ratio and gastrin levels then became similar between the groups at 12–15 months after eradication. In histological findings, inflammation and neutrophil activity decreased by 1–3 months, and atrophy in the corpus and metaplasia in the antrum decreased by 12–15 months.Conclusion : The results suggest that atrophic corpus gastritis and superficial gastritis are reversible, as indicated by both histological and serological findings in a long-term follow-up study.

Electronic Resource

0304-8853

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Physics

Electronic Resource

0006-291X

[abr] EGTA; ethylene glycol bis(β-aminoethyl ether) ; [abr] H-7; 1-(5-Isopuinolinesulfont1)-2-methylpiperazine dihydrochloride ; [abr] KH-solution; Krebs-Henseleit solution ; [abr] W-7; N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide ; [abr] [Ca]i; cytosolic free calcium concentrations

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0006-291X

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0006-291X

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0003-2670

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource

0005-2787

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Electronic Resource

0011-2240

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Medicine

Electronic Resource

0003-2670

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Chemistry and Pharmacology

Electronic Resource