Search Results - (Author, Cooperation:S. A. Karim)

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  1. 1
    Staff View
    Publication Date:
    2014-11-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenomatous Polyposis Coli Protein/deficiency/genetics ; Animals ; Cell Proliferation ; Cell Transformation, Neoplastic/metabolism/*pathology ; Elongation Factor 2 Kinase/deficiency/genetics/metabolism ; Enzyme Activation ; Genes, APC ; Intestinal Neoplasms/genetics/*metabolism/*pathology ; Male ; Mice ; Mice, Inbred C57BL ; Multiprotein Complexes/*metabolism ; Oncogene Protein p55(v-myc)/metabolism ; *Peptide Chain Elongation, Translational ; Peptide Elongation Factor 2/metabolism ; Ribosomal Protein S6 Kinases/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/*metabolism ; Wnt Proteins/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    P. Bailey ; D. K. Chang ; K. Nones ; A. L. Johns ; A. M. Patch ; M. C. Gingras ; D. K. Miller ; A. N. Christ ; T. J. Bruxner ; M. C. Quinn ; C. Nourse ; L. C. Murtaugh ; I. Harliwong ; S. Idrisoglu ; S. Manning ; E. Nourbakhsh ; S. Wani ; L. Fink ; O. Holmes ; V. Chin ; M. J. Anderson ; S. Kazakoff ; C. Leonard ; F. Newell ; N. Waddell ; S. Wood ; Q. Xu ; P. J. Wilson ; N. Cloonan ; K. S. Kassahn ; D. Taylor ; K. Quek ; A. Robertson ; L. Pantano ; L. Mincarelli ; L. N. Sanchez ; L. Evers ; J. Wu ; M. Pinese ; M. J. Cowley ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; L. A. Chantrill ; A. Mawson ; J. Humphris ; A. Chou ; M. Pajic ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; N. D. Merrett ; C. W. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; K. Moran-Jones ; N. B. Jamieson ; J. S. Graham ; F. Duthie ; K. Oien ; J. Hair ; R. Grutzmann ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; B. Rusev ; P. Capelli ; R. Salvia ; G. Tortora ; D. Mukhopadhyay ; G. M. Petersen ; D. M. Munzy ; W. E. Fisher ; S. A. Karim ; J. R. Eshleman ; R. H. Hruban ; C. Pilarsky ; J. P. Morton ; O. J. Sansom ; A. Scarpa ; E. A. Musgrove ; U. M. Bailey ; O. Hofmann ; R. L. Sutherland ; D. A. Wheeler ; A. J. Gill ; R. A. Gibbs ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Carcinoma, Pancreatic ; Ductal/classification/genetics/immunology/metabolism/pathology ; Cell Line, Tumor ; DNA Methylation ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genes, Neoplasm/*genetics ; Genome, Human/*genetics ; *Genomics ; Hepatocyte Nuclear Factor 3-beta/genetics ; Hepatocyte Nuclear Factor 3-gamma/genetics ; Histone Demethylases/genetics ; Homeodomain Proteins/genetics ; Humans ; Mice ; Mutation/*genetics ; Nuclear Proteins/genetics ; Pancreatic Neoplasms/*classification/*genetics/immunology/metabolism/pathology ; Prognosis ; Receptors, Cytoplasmic and Nuclear/genetics ; Survival Analysis ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, Genetic ; Transcriptome ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-12-04
    Publisher:
    Rockefeller University Press
    Print ISSN:
    0022-1007
    Electronic ISSN:
    1540-9538
    Topics:
    Medicine
    Keywords:
    Leukemia & Lymphoma
    Published by:
    http://www.rupress.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    ISSN:
    1573-7438
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Résumé Douze chèvres âgées de près de 3 mois ont été réparties entre 4 groupes égaux. Les chèvres des groupes 1 et 2 ont été infectées avec les virus ORF, suivi d'une infection àCorynebacterium pyogenes chez les groupes 1 et 3, trois jours après la première apparition des lésions dues au virus ORF. Les chèvres du groupe 4 représentaient le groupe témoin non-infecté. Des complications deux aux lésions ORF formées de croûtes purulentes et suintantes tout autour des lèvres ont été observées chez les chèvres du groupe 1. Les lésions ont persisté 24 jours, mais ont surtout été graves du 8e au 13e jour. Les chèvres du groupe 2 ont développé des lésions typiques de l'infection par virus ORF qui ont persisté pendant 10 jours, tandis que les chèvres du groupe 3 ont développé de petits nodules d'environ 1 cm de diamètre, 48 jours après l'inoculation deC. pyogenes qui ont duré 6 jours seulement. Aucune lésion n'a été remarquée chez les chèvres du groupe 4. Deux chèvres due groupe 1 atteintes d'ORF avec complications sont mortes après 16 et 22 jours respectivement.
    Abstract:
    Resumen Se formaron 4 grupos de cabras de 3 animales cada uno, con una edad aproximada de 3 meses. Las cabras de los grupos 1 y 2 se infectaron con el virus del ectima contagioso. A los 3 días de la aparición de las lesiones de ectima contagioso los grupos 1 y 2 se infectaron conCorynebacterium pyogenes. Las cabras del grupo 4 sirvieron de controles no infectados. Los animales del grupo 1 presentaron lesiones complicadas de ectima contagioso que consistían en escaras humedas y supurativas y que cubrian todos los labios. Las lesiones persistieron 24 días, siendo mas graves desde el día 8 al 13. Las cabras en el grupo 2 desarrollaron lesiones típicas de ectima contagioso que duraron 10 días, mientras que las del grupo 3 desarrollaron pequeños nódulos de cerca de 1 cm de diámetro 48 horas despues de la infección porC. pyogenes que persistieron solo 6 días. No se observaron lesiones en las cabras del grupo 4. Dos cabras del grupo 1 con ectima contagioso murieron a los 16 y 22 días respectivamente.
    Notes:
    Summary Twelve goats about 3 months of age were divided into 4 equal groups. Goats in Groups 1 and 2 were infected with orf virus followed byCorynebacterium pyogenes infection of Groups 1 and 3, 3 days after the first appearance of orf lesions. Goats in Group 4 were uninfected controls. Complicated orf lesions which consisted of wet suppurative scabs around the entire lips were observed in goats in Group 1. The lesions persisted for 24 days but were most severe from days 8 to 13. Goats in Group 2 developed lesions typical of orf virus infection that lasted 10 days, while goats in Group 3 developed small nodules of about 1 cm diameter, 48 hours following the introduction ofC. pyogenes, which persisted for only 6 days. No lesion was observed in goats in Group 4. Two goats in Group 1 with complicated orf died after 16 and 22 days respectively.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02236511

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1573-7438
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02359612

    Articles: DFG German National Licenses
  6. 6
    Karim, S. A. ; Hovell, P.
    Springer
    Published 1999
    Staff View
    ISSN:
    1573-1995
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Electrical Engineering, Measurement and Control Technology
    Notes:
    Abstract This paper investigates the changes that are required in networking technology for 'everything over IP' to become a reality. Initially the changes that are taking place in the telecommunications industry are reviewed. This review ranges from a discussion about the companies installing massive global IP networks to the emergence of novel routeing technologies, e.g. multi-protocol label switching (MPLS) and terabit router technologies. The role of existing telecommunications operators is then discussed, along with the reasons why they are developing interworking and intelligence layers based on distributed computing principles to support all their networks — mobile, fixed, broadband and IP.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1009625514107

    Articles: DFG German National Licenses