Search Results - (Author, Cooperation:S. A. Harvey)
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1R. N. Kettleborough ; E. M. Busch-Nentwich ; S. A. Harvey ; C. M. Dooley ; E. de Bruijn ; F. van Eeden ; I. Sealy ; R. J. White ; C. Herd ; I. J. Nijman ; F. Fenyes ; S. Mehroke ; C. Scahill ; R. Gibbons ; N. Wali ; S. Carruthers ; A. Hall ; J. Yen ; E. Cuppen ; D. L. Stemple
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-04-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Exome/genetics ; Female ; Gene Knockout Techniques ; Genetic Complementation Test ; Genome/*genetics ; Genomics ; Male ; Molecular Sequence Annotation ; Mutagenesis ; Mutation/genetics ; Phenotype ; Polymorphism, Single Nucleotide/genetics ; Zebrafish/*genetics/physiology ; Zebrafish Proteins/*genetics/metabolismPublished by: -
2Jeon, S., Rowe, A. M., Carroll, K. L., Harvey, S. A. K., Hendricks, R. L.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-05-22Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
3Staff View
ISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: The activity of choline acetyltransferase was used as an index of cholinergic structures in regions of rat brain. The activities of ATP citrate lyase and choline kinase correlated poorly with cholinergic activity in whole tissue fractions, contrasting with the good correlation between acetylcholinesterase and choline acetyltransferase. Choline acetyltransferase was preferentially localised in synaptosomes prepared from regions of high (striatum) or intermediate (cortex, medulla oblongata/pons) cholinergic activity. In general, this was not true for either choline kinase or ATP citrate lyase.Type of Medium: Electronic ResourceURL: -
4Booth, R. F. G. ; Harvey, S. A. K. ; Clark, J. B.
Oxford, UK : Blackwell Publishing Ltd
Published 1983Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Synaptosomes from normoxic and hypoxic rats were incubated aerobically in the presence and absence of veratridine. In the absence of veratridine, no significant difference was observed between the two types of preparation regarding either ATP/ADP ratio or 14CO2 or [14C]acetylcholine synthesis from D-[U-14C]glucose. However, in the presence of veratridine, significant reductions in the output of 14CO2 and [14C]acetylcholine by synaptosomes from hypoxic rats were apparent. It was concluded that irreversible metabolic lesions occur at the synapse as a result of hypoxia, which are apparent only when the metabolism of the preparation is accelerated to a level comparable with the maximal rate occurring in vivo. The presence of such lesions is further evidenced by the significant reductions in ATP/ADP ratio, 14CO2 output, and [14C]acetylcholine synthesis that occur in synaptosomes from hypoxic rats made anoxic in vitro and permitted to recover. Such decreases are not seen when synaptosomes from normoxic rats are similarly treated.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0022-5185Topics: Theology and Religious StudiesNotes: AUTHORS AND BOOKS REVIEWED OR NOTICEDURL: -
6Staff View
ISSN: 0022-5185Topics: Theology and Religious StudiesNotes: AUTHORS AND BOOKS REVIEWED OR NOTICEDURL: