Search Results - (Author, Cooperation:R. R. Brown)
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Publication Date: 2015-09-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Biophysics ; Career Mobility ; *Conservation of Natural Resources/history ; *Cooperative Behavior ; History, 21st Century ; Humanities ; *Interdisciplinary Communication ; Policy Making ; Research/history/manpower/*organization & administration ; *Research Design ; Research Personnel/*organization & administration ; Social Sciences ; Water SupplyPublished by: -
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ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
3Brown, R. R. ; Rose, D. P. ; Price, J. M. ; Wolf, H.
Oxford, UK : Blackwell Publishing Ltd
Published 1969Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
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ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The urine of rats maintained on a pyridoxine deficient diet was collected. The purified diet described by Brown, Miller and Miller6 was used except that vitamin-low casein was used at a level of 20 per cent and p-aminobenzoic acid and pyridoxine were omitted from the diet. In addition, this diet ...Type of Medium: Electronic ResourceURL: -
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ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Nicotinic acid is converted to 2-pyridone by a sequence of amidation, methylation and oxidation5, and recently it has been shown that oestrogens reduce the activity of N1-methylnicotinamide oxidase in mouse liver6. A similar effect of these hormones in the human might be expected to prevent the ...Type of Medium: Electronic ResourceURL: -
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ISSN: 1420-9071Keywords: Tryptophan ; macrophage ; monocyte ; interleukin-2 ; cancer ; Chlamydia ; ToxoplasmaSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Indoleamine 2,3-dioxygenase (IDO) is an interferon (IFN)-induced protein that initiates the metabolism of tryptophan along the kynurenine pathway. Although IDO can be induced by IFN-γ in many cell types, only mononuclear phagocytes have been shown to be induced to decyclize tryptophan by all three IFN classes. Since tryptophan is an essential amino acid necessary for a variety of metabolic processes, depletion of available tryptophan may be an important mechanism for control of rapidly-dividing microbial pathogens and tumors. The purpose of this review is to present evidence that documents the effects of IFN-induced IDO on prokaryotic and eukaryotic pathogens, as well as on a variety of tumor cell lines.Type of Medium: Electronic ResourceURL: -
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ISSN: 1432-2161Keywords: Key words Spine, injury, classification ; CT imagingSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Objective. Computed tomography (CT) has been demonstrated to be superior to radiography in identifying cervical vertebral injuries. However, many of these injuries may not be clinically significant, and require only minimal symptomatic and supportive treatment. It is therefore imperative that radiologists and spine surgeons have criteria for distinguishing between those injuries requiring surgical stabilization and those that do not. The authors propose a new classification of cervical vertebral injuries into two categories: major and minor. Design and patients. A data base, acquired on 1052 separate cervical injuries in 879 patients seen between 1983 and 1998, was reviewed. Four categories of injury based on mechanism [hyperflexion (four variants), hyperextension (two variants), rotary (two variants), and axial compression (five variants)] were identified. ”Major” injuries are defined as having either radiographic or CT evidence of instability with or without associated localized or central neurologic findings, or have the potential to produce the latter. ”Minor” injuries have no radiographic and/or CT evidence of instability, are not associated with neurologic findings, and have no potential to cause the latter. Results and conclusions. Cervical injury should be classified as ”major” if the following radiographic and/or CT criteria are present: displacement of more than 2 mm in any plane, wide vertebral body in any plane, wide interspinous/interlaminar space, wide facet joints, disrupted posterior vertebral body line, wide disc space, vertebral burst, locked or perched facets (unilateral or bilateral), ”hanged man” fracture of C2, dens fracture, and type III occipital condyle fracture. All other types of fractures may be considered ”minor”.Type of Medium: Electronic ResourceURL: -
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ISSN: 1432-2161Keywords: Key words Melorheostosis ; Dysplasia ; Bone ; Lower extremity ; Radiographs ; Specimen radiographsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Melorheostosis is an unusual mesenchymal dysplasia, which commonly presents on radiographs as longitudinal bars of hyperostosis in osseous structures. We present a case of melorheostosis in the lower extremity of a 20-year-old woman for which detailed radiologic– pathologic correlation was achieved due to amputation of the involved limb.Type of Medium: Electronic ResourceURL: