Search Results - (Author, Cooperation:R. M. Hoffman)
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1A. Impagliazzo ; F. Milder ; H. Kuipers ; M. V. Wagner ; X. Zhu ; R. M. Hoffman ; R. van Meersbergen ; J. Huizingh ; P. Wanningen ; J. Verspuij ; M. de Man ; Z. Ding ; A. Apetri ; B. Kukrer ; E. Sneekes-Vriese ; D. Tomkiewicz ; N. S. Laursen ; P. S. Lee ; A. Zakrzewska ; L. Dekking ; J. Tolboom ; L. Tettero ; S. van Meerten ; W. Yu ; W. Koudstaal ; J. Goudsmit ; A. B. Ward ; W. Meijberg ; I. A. Wilson ; K. Radosevic
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-08-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Hemagglutinin Glycoproteins, Influenza Virus/*chemistry/*immunology ; Humans ; Influenza A Virus, H1N1 Subtype/*immunology ; Influenza A Virus, H5N1 Subtype/*immunology ; Influenza Vaccines/*immunology ; Influenza, Human/*prevention & control ; Mice ; Protein Multimerization ; Protein Structure, SecondaryPublished by: -
2W. Tan ; W. Zhang ; A. Strasner ; S. Grivennikov ; J. Q. Cheng ; R. M. Hoffman ; M. Karin
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-02-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antigens, CD4/genetics/metabolism ; Antigens, CD8/genetics/metabolism ; Breast Neoplasms/*metabolism/*pathology ; CD4-Positive T-Lymphocytes/metabolism ; Cell Line, Tumor ; Female ; Forkhead Transcription Factors/metabolism ; Genes, RAG-1/genetics ; Humans ; I-kappa B Kinase/metabolism ; Lung Neoplasms/metabolism/secondary ; Lymphocytes, Tumor-Infiltrating/*metabolism ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis/pathology ; RANK Ligand/antagonists & inhibitors/*metabolism/pharmacology ; Receptor Activator of Nuclear Factor-kappa B/deficiency/genetics/*metabolism ; Receptor, ErbB-2/genetics/metabolism ; *Signal Transduction/drug effects ; T-Lymphocytes, Regulatory/*metabolismPublished by: -
3Laursen, N. S., Friesen, R. H. E., Zhu, X., Jongeneelen, M., Blokland, S., Vermond, J., van Eijgen, A., Tang, C., van Diepen, H., Obmolova, G., van der Neut Kolfschoten, M., Zuijdgeest, D., Straetemans, R., Hoffman, R. M. B., Nieusma, T., Pallesen, J., Turner, H. L., Bernard, S. M., Ward, A. B., Luo, J., Poon, L. L. M., Tretiakova, A. P., Wilson, J. M., Limberis, M. P., Vogels, R., Brandenburg, B., Kolkman, J. A., Wilson, I. A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Biochemistry, ImmunologyPublished by: -
4Staff View
ISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Exo–polygalacturonase (exo–PG) and endo–PG from Ascochyta pisi rapidly adsorbed to insoluble fragments of cell walls from pea leaflets as did the endo–PG inhibitor that was isolated from these organs. The wall fragments were hydrolysed by the exo– and endo–PG but the rates were, respectively, only 1–8 and 8% of the rate of hydrolysis of soluble polygalacturonic acid (PGA). Although the endo–PG inhibitor rapidly and completely inhibited the hydrolysis of soluble PGA by the endo–PG it had no effect on the rate of hydrolysis of pea cell wall fragments by this enzyme. Extracts of the intercellular fluid from pea leaflets contained only 4% of the inhibitor present in that organ and the remainder was presumably intracellular. These findings indicate that the endo–PG inhibitor may be less effective in vivo than was previously suspected.Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0006-3592Keywords: Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Clearing of agar plates containing ball-milled, delignified straw has been used for screening mutants of Penicillium funiculosum IMI 87160 iii. The effects of glycerol and a number of sugars on the clearing were investigated for selecting derepressed mutants. The β-glucosidase synthesis by one such mutant, C22c, in shake flasks containing straw was not repressed by 5% glycerol, whereas activities on filter paper, CM-cellulose, and p-nitrophenyl-β-xylosidase were only partially derepressed; xylanase was extensively derepressed. The evidence for separate control of the enzymes involved in the solubilization of straw is discussed.Additional Material: 2 Ill.Type of Medium: Electronic ResourceURL: