Search Results - (Author, Cooperation:R. L. Nelson)
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1Latest Papers from Table of Contents or Articles in PressS. S. Myers ; A. Zanobetti ; I. Kloog ; P. Huybers ; A. D. Leakey ; A. J. Bloom ; E. Carlisle ; L. H. Dietterich ; G. Fitzgerald ; T. Hasegawa ; N. M. Holbrook ; R. L. Nelson ; M. J. Ottman ; V. Raboy ; H. Sakai ; K. A. Sartor ; J. Schwartz ; S. Seneweera ; M. Tausz ; Y. Usui
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-05-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Air/analysis ; Atmosphere/chemistry ; Australia ; Breeding ; Carbon Dioxide/analysis/*pharmacology ; Crops, Agricultural/*chemistry/*drug effects/metabolism ; Diet ; Edible Grain/chemistry/drug effects/metabolism ; Fabaceae/chemistry/drug effects/metabolism ; Global Health/trends ; Humans ; Iron/analysis/deficiency/metabolism ; Japan ; *Nutritional Status ; Nutritive Value/*drug effects ; Photosynthesis/drug effects ; Phytic Acid/analysis/metabolism ; Public Health/*trends ; United States ; Zinc/analysis/deficiency/metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressS. McCouch ; G. J. Baute ; J. Bradeen ; P. Bramel ; P. K. Bretting ; E. Buckler ; J. M. Burke ; D. Charest ; S. Cloutier ; G. Cole ; H. Dempewolf ; M. Dingkuhn ; C. Feuillet ; P. Gepts ; D. Grattapaglia ; L. Guarino ; S. Jackson ; S. Knapp ; P. Langridge ; A. Lawton-Rauh ; Q. Lijua ; C. Lusty ; T. Michael ; S. Myles ; K. Naito ; R. L. Nelson ; R. Pontarollo ; C. M. Richards ; L. Rieseberg ; J. Ross-Ibarra ; S. Rounsley ; R. S. Hamilton ; U. Schurr ; N. Stein ; N. Tomooka ; E. van der Knaap ; D. van Tassel ; J. Toll ; J. Valls ; R. K. Varshney ; J. Ward ; R. Waugh ; P. Wenzl ; D. Zamir
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acclimatization/genetics ; Agriculture/economics/*methods/*trends ; Biodiversity ; Biological Specimen Banks ; Breeding ; Crops, Agricultural/genetics ; Food Supply/*statistics & numerical data ; Genes, Plant ; Humans ; Phenotype ; Seeds/geneticsPublished by: -
3Latest Papers from Table of Contents or Articles in PressWomble, P., Perrone, D., Jasechko, S., Nelson, R. L., Szeptycki, L. F., Anderson, R. T., Gorelick, S. M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Science and Policy, SociologyPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] More recently, normal Syrian hamster embryo cells have been used to determine directly the frequency of transformation by chemical carcinogens5,6. This phenomenon is inductive rather than selective, as the increase in frequency of transformation on a per cell basis is proportional to concentration ...Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesFarquhar, B. ; Robinson, M. ; Thomas, P. ; Murchie, S. ; Harch, A. ; Antreasian, P. G. ; Chesley, S. R. ; Miller, J. K. ; Owen, W. M. ; Williams, B. G. ; Yeomans, D. ; Dunham, D. ; Heyler, G. ; Holdridge, M. ; Nelson, R. L. ; Whittenburg, K. E. ; Ray, J. C. ; Carcich, B. ; Cheng, A. ; Chapman, C. ; Bell, J. F. ; Bell, M. ; Bussey, B. ; Clark, B. ; Domingue, D.
[s.l.] : Macmillian Magazines Ltd.
Published 2001Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The NEAR-Shoemaker spacecraft was designed to provide a comprehensive characterization of the S-type asteroid 433 Eros (refs 1,2,3), an irregularly shaped body with approximate dimensions of 34 × 13 × 13 km. Following the completion of its ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesOndrula, D. P. ; Nelson, R. L. ; Prasad, M. L. ; Coyle, B. W. ; Abcarian, H.
Springer
Published 1992Staff ViewISSN: 1530-0358Keywords: Colorectal surgery complications ; Preoperative risk assessmentSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Our aim was to analyze the predictive value of a variety of preoperative risk factors on operative outcomes. We reviewed all colorectal resections performed in a single hospital between January 1985 and May 1990. Nine hundred seventy-two resections were performed on 825 patients. We studied 17 preoperative risk factors generated from various medical risk categories. Using the multivariate discriminant function analysis, we calculated that 11 of the 17 risks were of significance in predicting outcomes (all with P ≤0.031). These factors included emergent operation, age ≥75 years, congestive heart failure (CHF), prior abdominal or pelvic radiation therapy, corticosteroid use, albumin 〈2.7 g/dl, chronic obstructive pulmonary disease (COPD), previous myocardial infarction (MI), diabetes, cirrhosis, and renal insufficiency. The classification function generated by the discriminant analysis was used to categorize patients into one of four risk groups depending on their “risk score.” The index used to develop each patient's “risk score” ranged from six points for an emergency operation to one point for diabetes. The mortality rates for the various risk groups were as follows: Group 1, zero to four points, 1 percent; Group 2, five to eight points, 10 percent; Group 3, 9 to 13 points, 19 percent; Group 4, 〉13 points, 33 percent. In contrast to previous reports, we showed that age ≥75 years alone is not a major preoperative risk factor but, rather, acts as a modifier for the other predictors of postoperative complications. We then assessed clinical questions concerning specific preoperative risks, such as steroid use, obesity, inflammatory bowel disease, COPD, and prior laparotomy, and their associated specific postoperative complications and have developed prevention strategies based on these findings. Through the use of the risk index, we also were able to assess an individual patient's operative risk more accurately.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-0827Keywords: Osteoclasts ; Sedimentation ; Isolation ; Cells ; BoneSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicinePhysicsNotes: Abstract A method is presented for separating osteoclasts from the heterogeneous population of bone and marrow cells. Cell suspensions were prepared from femora of young rabbits by mechanical dispersion. The starting cell suspension typically contained only 1.0%±0.5 osteoclasts. Following an initial 45 min of unit gravity sedimentation in a lucite chamber osteoclasts were primarily distributed in fractions 2–5. A second 45-min sedimentation of these pooled fractions yielded cell suspensions containing greater than 30% osteoclasts (as much as a 50-fold increase over starting percentages). Linear scan analysis, however, revealed that osteoclasts accounted for 73.14%±0.58 of the cell colume. Subsequent in vitro experiments demonstrated linear incorporation of3H-leucine into TCA precipitable protein for cells comprising the osteoclast fraction. Concomitant radiautographs revealed radioactive label in isolated osteoclasts.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1432-0843Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1432-0843Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The pharmacokinetics of vindesine were investigated in five patients with advanced cancer who were receiving the drug. Following a rapid IV bolus dose, vindesine kinetics were described by a triphasic serum decay curve compatible with a three-compartment open mammillary model. Serum half-lives were 2 min, 50 min, and 24 h for the fast, middle, and slow phases, respectively. The volume of the central compartment approximated the plasma volume in all patients studied. Distribution occurred quickly into a superficial tissue compartment in fairly rapid equilibrium with the plasma compartment, and also into a deep tissue compartment with slower redistribution to the central compartment. The large apparent volume of distribution and long elimination half-live suggest extensive tissue sequestration or delayed excretion of the drug in man. The slightly increased serum half-life of vindesine compared with published results for vinblastine may account for the greater degree and longer duration of marrow suppression seen clinically with vindesine.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesNelson, R. L. ; Go, V. L. W. ; McCullough, A. J. ; Ilstrup, D. M. ; Service, F. J.
Springer
Published 1986Staff ViewISSN: 1573-2568Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract To determine whether the autonomic nervous system has a direct effect on GIP secretion, six normal subjects received a 4-hr intraduodenal perfusion of glucose (225 mg/min) and polyethylene glycol on four successive days. During the latter 2 hr, either normal saline, propranolol, phentolamine, or atropine were infused intravenously. Glucose absorption was calculated by measuring glucose and polyethylene glycol following luminal aspiration distal to the perfusion site. Basal and peak or nadir values in the saline study of plasma glucose, insulin, glucagon, and GIP were similar to the other three studies prior to autonomic blockade. During the latter 2 hr of the glucose perfusion, the plasma glucose and glucagon responses to saline did not differ from responses to the three blocking agents. Phentolamine but not atropine or propranolol resulted in a greater insulin response compared to saline (3247±762 vs 1348±388 μU/ml/120 min,P〈0.01). GIP was not significantly affected by phentolamine (18,146±4574), propranolol (7585±5854), or atropine (15,797±6297) compared to saline (11,717±5204 pg/ml/120 min). Glucose absorption was unaffected by infusions of saline, phentolamine, and propranolol, but was increased following atropine infusion (5841±1120 vs 1044±808 mg/120 min,P〈0.02). There appears to be no direct effect of the autonomic nervous system on glucose-induced secretion of GIP.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1573-4927Keywords: starch gel electrophoresis ; L-glutamate dehydrogenase (GLUD)Source: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNotes: Abstract A method for the starch gel electrophoresis of human L-glutamate dehydrogenase (GLUD) is described, as is the tissue distribution of GLUD detected by this method. Extracts of livers from 200 Whites were analyzed without demonstration of an electrophoretic variant. The molecular size was estimated to be 330,000 and the isoelectric point pH 4.83.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1573-4927Keywords: ammonia metabolism, enzymes of ; L-glutamate dehydrogenase as a linking enzymeSource: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyNotes: Abstract The use of L-glutamate dehydrogenase (GLUD) as a reagent in staining mixtures to detect the isozymes of enzymes which catalyze the production of ammonia has been investigated. Methods have been devised for the electrophoresis and detection, using GLUD, of seven enzymes: cytidine deaminase, adenosine deaminase, adenosine monophosphate deaminase, arginase, argininosuccinase, D-amino acid oxidase, and D-aspartate oxidase. GLUD-linked staining methods appear to be sensitive, specific, and of general application.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesHiester, N. K. ; Rodding, S. B. ; Nelson, R. L. ; Vermeulen, Theodore
Hoboken, NJ : Wiley-Blackwell
Published 1957Staff ViewISSN: 0001-1541Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyProcess Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: