Search Results - (Author, Cooperation:R. James)

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  1. 1
    Staff View Availability Links
    Person(s):
    Schwarzer, Guido [Verfasser]; Carpenter, James R. [Verfasser]; Rücker, Gerta [Verfasser]
    Type of Medium:
    Book
    Pages:
    xii, 252 Seiten, Illustrationen
    ISBN:
    9783319214153
    Series Statement:
    Use R!
    URL:
    Inhaltsverzeichnis
    Klappentext
    Language:
    English
    Recall This
    Description / Table of Contents
    Klappentext

    Printed Books
  2. 2
    Mingle, James R.
    San Francisco : Jossey Bass Publ.
    Published 1981
    Staff View Availability
    Person(s):
    Mingle, James R.
    Type of Medium:
    Unknown
    Pages:
    394 S.
    ISBN:
    0875895077
    Language:
    English
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    Printed Books
  3. 3
    Gress, James R. ; Purpel, David E.
    Berkeley : McCutchan Publ.
    Published 1988
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    Person(s):
    Gress, James R.; Purpel, David E.
    Type of Medium:
    Unknown
    Pages:
    636 S.
    Edition:
    2nd ed.
    ISBN:
    0821106171
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    Printed Books
  4. 4
    Staff View Availability
    Person(s):
    Joint Committee on Standards for Educational Evaluation; Sanders, James R.; Beywl, Wolfgang
    Type of Medium:
    Unknown
    Pages:
    310 S.
    ISBN:
    3810027669
    Uniform Title:
    aus dem Amerikanischen
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    Printed Books
  5. 5
    Hencley, Stephen P., 1924- ; Yates, James R.
    Berkeley, Calif. : McCutchan Pub. Corp.
    Published 1974
    Staff View Availability
    Person(s):
    Hencley, Stephen P., 1924-; Yates, James R.,
    Type of Medium:
    Book
    Pages:
    xii, 510 p., illus., 24 cm.
    ISBN:
    0821120018
    Language:
    English
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    Printed Books
  6. 6
    Deringer, James R. ; Ely, R. James ; Stauffacher, Cynthia V. ; Bohach, Gregory A.

    Oxford BSL : Blackwell Science Ltd
    Published 1996
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The goal of this study was to investigate the molecular interaction between superantigens and the T-cell receptor (TCR). Using a quantitative polymerase chain reaction (PCR) to assess T-cell proliferation profiles, we found that SEB, SEC1, SEC2 and SEC3 expanded human T cells bearing Vβ3, Vβ12, Vβ13.2, Vβ14, Vβ15, Vβ17 and Vβ20. SEC2 and SEC3 have the additional ability to expand T cells bearing Vβ13.1, and their expansion of Vβ3 was markedly reduced compared to SEB and SEC1. Based on the activity of SEC1 mutants containing single amino acid substitutions, we concluded that the differential abilities of these native toxins to stimulate Vβ3 and Vβ13.1 was determined by the residue in position 26, located in the base of the SEC α3 cavity. The SEC1 mutant, in which Val in position 26 was substituted with the analogous SEC2/SEC3 residue (Tyr), generated a Vβ expansion profile that was indistinguishable from those generated by SEC2 and SEC3. Using these findings, the co-ordinates of a recently reported murine TCR β-chain crystal structure, and other documented information, we propose a compatible molecular model for the interaction of SEC3 with the T-cell receptor. In this model complex, the complementarity-determining regions (CDRs) 1 and 2 and the hypervariable loop 4 of the Vβ element contact SEC3 predominantly through residues in the α3 cavity of the toxin. CDR3 of the β chain is not involved in any toxin contacts. The proposed model not only includes contacts identified in previous mutagenesis studies, but is also consistent with the ability of tyrosine and valine in position 26 to differentially affect the expansion of Vβs 3 and 13.1 by the SEC superantigens.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1365-2958.1996.1381506.x

    Articles: DFG German National Licenses
  7. 7
    Viding, Essi ; Blair, R. James R. ; Moffitt, Terrie E. ; Plomin, Robert

    Oxford, UK : Blackwell Publishing
    Published 2005
    Staff View
    ISSN:
    1469-7610
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Psychology
    Notes:
    Background:  Individuals with early warning signs of life-long psychopathy, callous-unemotional traits (CU) and high levels of antisocial behaviour (AB) can be identified in childhood. We report here the first twin study of high levels of psychopathic tendencies in young children.Methods:  At the end of the first school year, teachers provided ratings of CU and AB for 3687 twin pairs from the Twins Early Development Study (TEDS). For the analyses of extreme CU, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on the CU scale (612 probands, 459 twin pairs). For the analysis of extreme AB, we selected same-sex twin pairs where at least one twin scored 1.3 or more standard deviations above the mean on AB scale (444 probands, 364 twin pairs). Furthermore, the extreme AB sample was divided into those who were also extreme on CU (children with psychopathic tendencies; 234 probands, 187 twin pairs) and those who did not score in the extreme for CU (children without psychopathic tendencies; 210 probands, 177 twin pairs).Results:  DeFries–Fulker extremes analysis indicated that exhibiting high levels of CU is under strong genetic influence. Furthermore, separating children with AB into those with high and low levels of CU showed striking results: AB in children with high levels of CU is under extremely strong genetic influence and no influence of shared environment, whereas AB in children with low levels of CU shows moderate genetic and shared environmental influence.Conclusions:  The remarkably high heritability for CU, and for AB children with CU, suggests that molecular genetic research on antisocial behaviour should focus on the CU core of psychopathy. Our findings also raise questions for public policy on interventions for antisocial behaviour.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1469-7610.2004.00393.x

    Articles: DFG German National Licenses
  8. 8
    Weeks, James R. ; Collins, R. James
    Springer
    Published 1964
    Staff View
    ISSN:
    1432-2072
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Self-maintained morphine addicted rats were prepared by implanting chronic venous cannulas and fitting the rats with a device permitting relatively free movement and also enabling them to obtain morphine injections at will by pressing a lever. Three factors modifying voluntary morphine intake were studied. 1. Using a continuous reinforcement schedule, progressively decreasing the size of the morphine dose led to a greater number of doses daily. Compensation was incomplete in that the total daily morphine intake decreased. 2. Progressively increasing a fixed ratio reinforcement schedule up to about FR-75, caused rats to continue responding on the lever until the dose was obtained. Above FR-75 responding became intermittent and daily morphine decreased as the time interval between doses increased. 3. Continuous intravenous infusion of a second drug, leaving voluntary access to morphine at FR-10, led to decreased morphine intake following infusion of morphine itself, codeine and meperidine. Nalorphine infusion increased morphine intake. Effectiveness of infusions varied with the infusion rate.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00413156

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1432-2072
    Keywords:
    Abuse liability ; Addiction ; Behavior ; Monkey ; Physical dependence ; Rat ; Reinforcement ; Self-administration
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract A total 31 psychoactive drugs were offered to groups of naive rats for IV self-administration and an injection rate greater than that for rats offered only saline indicated reinforcement. Two protocols were used: in the first, rats were offered drug at a selected dose for 5 days, then the dose was reduced by 1 log unit (to 0.1 the original dose) for an additional 4 days; in the second, rats were offered saline for 3 days as a ‘prescreen’ to eliminate rats with high or low operant-injection rates. Drug was offered to acceptable rats for 5 days, then the dose was reduced 0.5 log unit (to 0.32 the original dose) for 5 more days. A scoring system, based upon the injection rates during the last 3 days of each period, describes the reinforcing action. Scores were dose-related. Tests on both protocols gave similar results. Data from monkey studies have been reported for 27 of the drugs tested. Of these drugs, 18 were reinforcers and six were nonreinforcers in both species, nalorphine and ethylketazocine were reinforcers only in rats, and ethanol was a reinforcer only in monkeys.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00426372

    Articles: DFG German National Licenses
  10. 10
    Collins, R. James ; Weeks, James R.
    Springer
    Published 1965
    Staff View
    ISSN:
    1432-1912
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary A method is described for obtaining potency estimates of narcotic analgesics to morphine in experimental addict rats. Drugs were administered through a chronic right heart cannula and intake was under the rat's voluntary control. Animals were offered two doses of morphine (3.2 and 10 mg/kg/injection) and two doses of test compound on a fixed ratio reinforcement schedule of 10:1. Logarithm of the daily number of injections taken was used as the effect metameter. Each potency estimate was based on results in four rats. Rats averaged 137 mg/kg/day of morphine when offered 10 mg/kg/injection. A diurnal variation in opiate intake was observed, the nighttime rate being about one-third greater than the daytime rate. Morphine intake measured before and after the assay period was essentially unchanged. Potency estimates and the 95% fiducial interval were: dihydromorphinone = 10 (5.2−19) × morphine, methadone = 3.4 (2.7−4.6) × morphine and codeine = 0.67 (0.45−1.0) × morphine. Analgesic activity for codeine was not proportional to its ability to substitute for morphine in addict rats.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00246557

    Articles: DFG German National Licenses
  11. 11
    Collins, R. James ; Weeks, James R.
    Springer
    Published 1967
    Staff View
    ISSN:
    1432-2072
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Dexoxadrol, dextromethorphan and meperidine were given by continuous intravenous infusion to selfmaintained morphine dependent rats. Dexoxadrol and dextromethorphan did not significantly decrease the rate of morphine self-administration. Meperidine produced a dose related decrease in the rate of morphine injections. The failure of dexoxadrol to reduce morphine intake is evidence that it will probably not produce opioid-like addiction liability in man.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00404605

    Articles: DFG German National Licenses
  12. 12
    Weeks, James R. ; Collins, R. James
    Springer
    Published 1979
    Staff View
    ISSN:
    1432-2072
    Keywords:
    Morphine ; Rat ; Self-administration ; Physical dependence ; Addiction ; Reinforcement ; Behavior
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Groups of naive rats were offered morphine sulfate for self-administration in doses of 0.0032–10 mg/kg for 6 days. On day 7 saline was substituted for morphine. Loss of weight was taken as physiological evidence of dependence. Rats that did not lose weight formed a single population whose mean injection rate did not differe from control rats receiving only saline injections. Injection rates for rats losing weight were log-normally distributed, and the mean of the logarithms of the injection rates was linearly related to the logarithm of the dose. Mean daily injection rates averaged 12 for controls, 23 at 10 mg/kg, and 411 at 0.01 mg/kg. A transient increase in morphine intake after an injection of nalorphine was taken as behavioral evidence of dependence. Nalorphine increased morphine intake when rats were self-injecting 0.32 and 1.0 mg/kg of morphine, but not 0.032 or 0.1 mg/kg. The reinforcing property of morphine may occur without behavioral evidence of dependence.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00433045

    Articles: DFG German National Licenses
  13. 13
    Staff View
    Type of Medium:
    article
    Publication Date:
    1998
    Keywords:
    Ländervergleich ; Verhalten ; Wahrnehmung ; Kindesmissbrauch ; Soziale Arbeit ; Bewertung ; Student
    In:
    The British journal of social work, Bd. 28 (1998) H. 1, S. 57-72, 0045-3102
    Language:
    English
    Note:
    Tabellen, Literaturangaben

    FIS Bildung Literaturdatenbank
  14. 14
    Staff View
    Publication Date:
    2018-04-19
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    environmental science
    Published by:
    http://royalsocietypublishing.org/

    Latest Papers from Table of Contents or Articles in Press
  15. 15
    R. James White, Martin R. Wilkins
    American Heart Association (AHA)
    Published 2018
    Staff View
    Publication Date:
    2018-05-30
    Publisher:
    American Heart Association (AHA)
    Electronic ISSN:
    1524-4539
    Topics:
    Medicine
    Keywords:
    Pulmonary Biology, Animal Models of Human Disease, Cell Signaling/Signal Transduction, Vascular Biology
    Published by:
    http://www.americanheart.org/

    Latest Papers from Table of Contents or Articles in Press
  16. 16
    Staff View
    Publication Date:
    2018-01-26
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    0031-9007
    Electronic ISSN:
    1079-7114
    Topics:
    Physics
    Keywords:
    General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.
    Published by:
    http://www.aps.org/

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  17. 17
    Staff View
    Publication Date:
    2013-08-10
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Administration, Intravenous ; Adult ; Animals ; Cytokines/immunology ; Female ; Humans ; Immunity, Cellular ; Malaria Vaccines/*administration & dosage/adverse effects/*immunology ; Malaria, Falciparum/*prevention & control ; Male ; Mice ; Plasmodium falciparum/*immunology ; Sporozoites/immunology ; T-Lymphocytes/immunology ; Vaccination/adverse effects/methods
    Published by:
    http://www.aaas.org/

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  18. 18
    C. Rotimi ; A. Abayomi ; A. Abimiku ; V. M. Adabayeri ; C. Adebamowo ; E. Adebiyi ; A. D. Ademola ; A. Adeyemo ; D. Adu ; D. Affolabi ; G. Agongo ; S. Ajayi ; S. Akarolo-Anthony ; R. Akinyemi ; A. Akpalu ; M. Alberts ; O. Alonso Betancourt ; A. M. Alzohairy ; G. Ameni ; O. Amodu ; G. Anabwani ; K. Andersen ; F. Arogundade ; O. Arulogun ; D. Asogun ; R. Bakare ; N. Balde ; M. L. Baniecki ; C. Beiswanger ; A. Benkahla ; L. Bethke ; M. Boehnke ; V. Boima ; J. Brandful ; A. I. Brooks ; F. C. Brosius ; C. Brown ; B. Bucheton ; D. T. Burke ; B. G. Burnett ; S. Carrington-Lawrence ; N. Carstens ; J. Chisi ; A. Christoffels ; R. Cooper ; H. Cordell ; N. Crowther ; T. Croxton ; J. de Vries ; L. Derr ; P. Donkor ; S. Doumbia ; A. Duncanson ; I. Ekem ; A. El Sayed ; M. E. Engel ; J. C. Enyaru ; D. Everett ; F. M. Fadlelmola ; E. Fakunle ; K. H. Fischbeck ; A. Fischer ; O. Folarin ; J. Gamieldien ; R. F. Garry ; S. Gaseitsiwe ; R. Gbadegesin ; A. Ghansah ; M. Giovanni ; P. Goesbeck ; F. X. Gomez-Olive ; D. S. Grant ; R. Grewal ; M. Guyer ; N. A. Hanchard ; C. T. Happi ; S. Hazelhurst ; B. J. Hennig ; C. Hertz ; Fowler ; W. Hide ; F. Hilderbrandt ; C. Hugo-Hamman ; M. E. Ibrahim ; R. James ; Y. Jaufeerally-Fakim ; C. Jenkins ; U. Jentsch ; P. P. Jiang ; M. Joloba ; V. Jongeneel ; F. Joubert ; M. Kader ; K. Kahn ; P. Kaleebu ; S. H. Kapiga ; S. K. Kassim ; I. Kasvosve ; J. Kayondo ; B. Keavney ; A. Kekitiinwa ; S. H. Khan ; P. Kimmel ; M. C. King ; R. Kleta ; M. Koffi ; J. Kopp ; M. Kretzler ; J. Kumuthini ; S. Kyobe ; C. Kyobutungi ; D. T. Lackland ; K. A. Lacourciere ; G. Landoure ; R. Lawlor ; T. Lehner ; M. Lesosky ; N. Levitt ; K. Littler ; Z. Lombard ; J. F. Loring ; S. Lyantagaye ; A. Macleod ; E. B. Madden ; C. R. Mahomva ; J. Makani ; M. Mamven ; M. Marape ; G. Mardon ; P. Marshall ; D. P. Martin ; D. Masiga ; R. Mason ; M. Mate-Kole ; E. Matovu ; M. Mayige ; B. M. Mayosi ; J. C. Mbanya ; S. A. McCurdy ; M. I. McCarthy ; H. McIlleron ; S. O. Mc'Ligeyo ; C. Merle ; A. O. Mocumbi ; C. Mondo ; J. V. Moran ; A. Motala ; M. Moxey-Mims ; W. S. Mpoloka ; C. L. Msefula ; T. Mthiyane ; N. Mulder ; G. Mulugeta ; D. Mumba ; J. Musuku ; M. Nagdee ; O. Nash ; D. Ndiaye ; A. Q. Nguyen ; M. Nicol ; O. Nkomazana ; S. Norris ; B. Nsangi ; A. Nyarko ; M. Nyirenda ; E. Obe ; R. Obiakor ; A. Oduro ; S. F. Ofori-Acquah ; O. Ogah ; S. Ogendo ; K. Ohene-Frempong ; A. Ojo ; T. Olanrewaju ; J. Oli ; C. Osafo ; O. Ouwe Missi Oukem-Boyer ; B. Ovbiagele ; A. Owen ; M. O. Owolabi ; L. Owolabi ; E. Owusu-Dabo ; G. Pare ; R. Parekh ; H. G. Patterton ; M. B. Penno ; J. Peterson ; R. Pieper ; J. Plange-Rhule ; M. Pollak ; J. Puzak ; R. S. Ramesar ; M. Ramsay ; R. Rasooly ; S. Reddy ; P. C. Sabeti ; K. Sagoe ; T. Salako ; O. Samassekou ; M. S. Sandhu ; O. Sankoh ; F. S. Sarfo ; M. Sarr ; G. Shaboodien ; I. Sidibe ; G. Simo ; M. Simuunza ; L. Smeeth ; E. Sobngwi ; H. Soodyall ; H. Sorgho ; O. Sow Bah ; S. Srinivasan ; D. J. Stein ; E. S. Susser ; C. Swanepoel ; G. Tangwa ; A. Tareila ; O. Tastan Bishop ; B. Tayo ; N. Tiffin ; H. Tinto ; E. Tobin ; S. M. Tollman ; M. Traore ; M. J. Treadwell ; J. Troyer ; M. Tsimako-Johnstone ; V. Tukei ; I. Ulasi ; N. Ulenga ; B. van Rooyen ; A. P. Wachinou ; S. P. Waddy ; A. Wade ; M. Wayengera ; J. Whitworth ; L. Wideroff ; C. A. Winkler ; S. Winnicki ; A. Wonkam ; M. Yewondwos ; T. sen ; N. Yozwiak ; H. Zar
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-06-21
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa ; Disease/*genetics ; England ; Genetics, Medical/trends ; Genome-Wide Association Study/*trends ; Genomics/*trends ; Health ; Humans ; National Institutes of Health (U.S.) ; United States
    Published by:
    http://www.aaas.org/

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  19. 19
    Staff View
    Publication Date:
    2018-11-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Electronic ISSN:
    2375-2548
    Topics:
    Natural Sciences in General
    Published by:
    http://www.aaas.org/

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  20. 20
    Juliana M. Sa, Sarah R. Kaslow, Michael A. Krause, Viviana A. Melendez–Muniz, Rebecca E. Salzman, Whitney A. Kite, Min Zhang, Roberto R. Moraes Barros, Jianbing Mu, Paul K. Han, J. Patrick Mershon, Christine E. Figan, Ramoncito L. Caleon, Rifat S. Rahman, Tyler J. Gibson, Chanaki Amaratunga, Erika P. Nishiguchi, Kimberly F. Breglio, Theresa M. Engels, Soundarapandian Velmurugan, Stacy Ricklefs, Judith Straimer, Nina F. Gnadig, Bingbing Deng, Anna Liu, Ababacar Diouf, Kazutoyo Miura, Gregory S. Tullo, Richard T. Eastman, Sumana Chakravarty, Eric R. James, Kenneth Udenze, Suzanne Li, Daniel E. Sturdevant, Robert W. Gwadz, Stephen F. Porcella, Carole A. Long, David A. Fidock, Marvin L. Thomas, Michael P. Fay, B. Kim Lee Sim, Stephen L. Hoffman, John H. Adams, Rick M. Fairhurst, Xin–zhuan Su, Thomas E. Wellems
    National Academy of Sciences
    Published 2018
    Staff View
    Publication Date:
    2018-12-05
    Publisher:
    National Academy of Sciences
    Print ISSN:
    0027-8424
    Electronic ISSN:
    1091-6490
    Topics:
    Biology
    Medicine
    Natural Sciences in General
    Published by:
    http://www.nasonline.org/

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