Search Results - (Author, Cooperation:R. Goel)
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1Latest Papers from Table of Contents or Articles in PressM. S. Kim ; S. M. Pinto ; D. Getnet ; R. S. Nirujogi ; S. S. Manda ; R. Chaerkady ; A. K. Madugundu ; D. S. Kelkar ; R. Isserlin ; S. Jain ; J. K. Thomas ; B. Muthusamy ; P. Leal-Rojas ; P. Kumar ; N. A. Sahasrabuddhe ; L. Balakrishnan ; J. Advani ; B. George ; S. Renuse ; L. D. Selvan ; A. H. Patil ; V. Nanjappa ; A. Radhakrishnan ; S. Prasad ; T. Subbannayya ; R. Raju ; M. Kumar ; S. K. Sreenivasamurthy ; A. Marimuthu ; G. J. Sathe ; S. Chavan ; K. K. Datta ; Y. Subbannayya ; A. Sahu ; S. D. Yelamanchi ; S. Jayaram ; P. Rajagopalan ; J. Sharma ; K. R. Murthy ; N. Syed ; R. Goel ; A. A. Khan ; S. Ahmad ; G. Dey ; K. Mudgal ; A. Chatterjee ; T. C. Huang ; J. Zhong ; X. Wu ; P. G. Shaw ; D. Freed ; M. S. Zahari ; K. K. Mukherjee ; S. Shankar ; A. Mahadevan ; H. Lam ; C. J. Mitchell ; S. K. Shankar ; P. Satishchandra ; J. T. Schroeder ; R. Sirdeshmukh ; A. Maitra ; S. D. Leach ; C. G. Drake ; M. K. Halushka ; T. S. Prasad ; R. H. Hruban ; C. L. Kerr ; G. D. Bader ; C. A. Iacobuzio-Donahue ; H. Gowda ; A. Pandey
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-05-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Cells, Cultured ; Databases, Protein ; Fetus/metabolism ; Fourier Analysis ; Gene Expression Profiling ; Genome, Human/genetics ; Hematopoietic Stem Cells/cytology/metabolism ; Humans ; Internet ; Mass Spectrometry ; Molecular Sequence Annotation ; Open Reading Frames/genetics ; Organ Specificity ; Protein Biosynthesis ; Protein Isoforms/analysis/genetics/metabolism ; Protein Sorting Signals ; Protein Transport ; Proteome/analysis/chemistry/genetics/*metabolism ; *Proteomics ; Pseudogenes/genetics ; RNA, Untranslated/genetics ; Reproducibility of Results ; Untranslated Regions/geneticsPublished by: -
2Latest Papers from Table of Contents or Articles in PressMurcia, O., Jover, R., Egoavil, C., Perez-Carbonell, L., Juarez, M., Hernandez-Illan, E., Rojas, E., Alenda, C., Balaguer, F., Andreu, M., Llor, X., Castells, A., Boland, C. R., Goel, A.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-06-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressChen, Y., Chaudhary, N., Yang, N., Granato, A., Turner, J. A., Howard, S. L., Devereaux, C., Zuo, T., Shrestha, A., Goel, R. R., Neuberg, D., Wesemann, D. R.
Rockefeller University Press
Published 2018Staff ViewPublication Date: 2018-05-08Publisher: Rockefeller University PressPrint ISSN: 0022-1007Electronic ISSN: 1540-9538Topics: MedicineKeywords: Mucosal ImmunologyPublished by: -
4Articles: DFG German National LicensesPadam, G. K. ; Tripathi, R. B. ; Singh, S. ; Rao, S. U. M. ; Jain, K. ; Kotnala, R. K. ; Goel, R. C. ; Khurana, B. S. ; Khullar, S. M. ; Das, B. K.
[S.l.] : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Tungsten-doped YBa2Cu3O7−x superconducting samples are characterized with the help of resistivity, crystal structural, microstructural, density d, and critical current density Jc studies for doping concentrations varying from 0.00 to 0.14 mol % of WO3. It has been found that doping of WO3 has hardly any influence of Tc, whereas it seems that d and Jc are affected. d and Jc of the samples increase in the range 0〈WO3≤0.04, but above this range, both start decreasing. The maximum Jc obtained at 77 K and zero magnetic field in YBa2Cu3O7−x doped with 0.04 mol % of WO3 is 450 A/cm2. The lower concentrations (〈0.04 mol %) seem to improve the density, whereas higher concentrations lead to porous structure and also induce the formation of BaCuO2 and Y2Ba1Cu1O5 nonsuperconducting phase as revealed by scanning electron microscopy, energy dispersive spectral, and x-ray diffraction analyses. The x-ray diffraction analysis also showed no appreciable change in the lattice parameters with WO3 doping. It appears that the WO3 doping changes the microstructure of YBa2Cu3O7−x to influence its Jc.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0301-0104Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-0673Source: Springer Online Journal Archives 1860-2000Topics: MathematicsPhysicsType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesHirte, H. ; Goel, R. ; Major, P. ; Seymour, L. ; Huan, S. ; Stewart, D. ; Yau, J. ; Arnold, A. ; Holohan, S. ; Waterfield, B. ; Bates, S. ; Bennett, K. ; Walsh, W. ; Elias, I.
Springer
Published 2000Staff ViewISSN: 1569-8041Keywords: dosing ; inhibitor ; matrix metalloproteinase ; pharmacokinetics ; solid tumours ; toxicitySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Background:This phase I study was performed to evaluatethe safety, tolerability, and efficacy of the oral matrixmetalloproteinase inhibitor BAY 12-9566 in patients with advanced solidtumours, and to identify the maximum tolerated dose and dose for use insubsequent studies. Patients and methods:BAY 12-9566 was administered to 29 patientsat doses ranging from 100 mg o.d. to 1600 mg (given either 400 mg q.i.d. or800 mg b.i.d.). Blood samples for pharmacokinetic analyses were drawn on days1–5, day 15 and days 29 and 30. Patients were continued on daily oraltreatment of BAY 12-9566 until a dose limiting toxicity or tumour progressionoccurred. Results:A maximum tolerated dose was not defined because plasmalevels of BAY 12-9566 could not be sufficiently increased, even withescalating doses of drug. Pharmacokinetic analysis suggested that absorptionwas saturable at higher doses. The predominant toxicities related to drug wereasymptomatic reversible effects on platelets and transaminases and mildanemia. There were no significant musculoskeletal toxicities. No objectiveresponses were seen at the doses tested, but stable disease was observed insome patients based on tumour measurements. Conclusions:The recommended dose of BAY 12-9566 for furtherstudies is 800 mg b.i.d. as this dose provides maximal plasma levels that canbe achieved with a convenient dosing schedule for a chronically administeredoral agentType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1573-4811Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Abstracts are not published in this journalType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1573-2568Keywords: RADIATION ; PROCTOSIGMOIDITIS ; SUCRALFATE ; RECTAL BLEEDINGSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Rectal bleeding due to radiationproctosigmoiditis is often difficult to manage. We hadearlier shown the efficacy of short-term therapy withtopical sucralfate in controlling bleeding in theradiation proctosigmoiditis. We now report our long-termresults with this form of therapy. The study comprised26 patients with radiation proctosigmoiditis.Sigmoidoscopically, 9 (34.6% patients had severechanges, 15 (57.69%) had moderate, and 2 (7.69%) hadmild changes. Severity of bleeding was graded as severe(〉15 episodes per week), moderate (8-14 episodes perweek), mild (2-7 episodes per week), negligible (1 episode per week), or nil (no bleeding). Tenpatients had moderate rectal bleeding, while 16 hadsevere bleeding. All patients were treated with 20 ml of10% rectal sucralfate suspension enemas twice a day until bleeding per rectum ceased orfailure of therapy was acknowledged. Response to therapywas considered good whenever the severity of bleedingshowed improvement by a change of two grades. Rectally administered sucralfate achieved good responsein 20 (76.9%) patients at 4 weeks, 22 (84.6%) patientsat 8 weeks, and 24 (92.3%) patients at 16 weeks. Thischange was significant by Wilcoxon matched-pairs signed-ranks test. Two patients requiredsurgery due to poor response. Over a median follow-up of45.5 months (range 5-73 months) after cessation ofbleeding, 17 (70.8%) patients had no further bleeding while 7 (22.2%) had recurrence of bleeding. Allrecurrences responded to short-term reinstitution oftherapy. No treatmentrelated complications wereobserved. Ten patients had other associated latetoxicity due to pelvic irradiation in the form ofasymptomatic rectal stricture (N = 3), rectovaginalfistula (N = 1), intestinal stricture (N = 1), vaginalstenosis (N = 1), and hematuria (N = 6). Three patients had progression of the primary disease in theform of pelvic recurrence (N = 2) and hepatic metastases(N = 1). We conclude that topical sucralfate induces alasting remission in a majority of patients with moderate to severe rectal bleeding due toradiation proctosigmoiditis.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesKhurana, B. S. ; Tripathi, R. B. ; Khullar, S. M. ; Kotnala, R. K. ; Singh, Satbir ; Jain, K. ; Reddi, B. V. ; Goel, R. C. ; Das, B. K.
Springer
Published 1989Staff ViewISSN: 1573-4811Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0003-3146Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyPhysicsDescription / Table of Contents: Polyamidsäuren wurden aus Pyromellithsäuredianhydrid und Benzidin (B) sowie Hydrazin (H) dargestellt und druch Viskositätsmessungen in Dimethylformamid (DMF) charakterisiert. Die Hydrolysestabilitßat wurde nach 20tägige Aufewahrung der DMF-Lösungen an der Luft bei Raumtemperatur ermittelt. Es ergab sich eine Viskositätsabnahme für die B-Polymeren und die Copolymeren mit B und H. Diese Verminderung ist für die Copolymeren geringer.Das thermische Verhalten der Polyamidsäuren und Polyimide wurde mittels thermogravimetrischer und differentialthermoanalytischer Methoden untersucht. Die Copolyamidsäuren wiesen eine größere thermische Stabilität als die Polyamidsären aus B auf, während die Copolyimide eine geringere Stabilität als die Polyimide aus B aufwiesen. Die thermische Cyclodehydrierung der Polyamidsäuren zu den polyimiden fand bei den Copolymeren bei geringeren Temperaturen als bei den B-Polymeren statt.Notes: The polyamic acids from pyromellitic dianhydride, benzidine (B) and hydrazine (H) were prepared and characterized by intrinsic viscosity measurements in dimethylformamide (DMF) solutions. The hydrolytic stability of these polymers was determined by keeping the DMF solution in presence of air at room temperature for 20 days. A decrease in ηinh was observed for the B-polymers and copolymers of B and H. This reduction was less in the copolymers.The thermal behaviour of polyamic acids and polyimides was studied by thermogravimetric and differential thermal analysis techniques. The copolyamic acids were found to be thermally more stable than polyamic acid from B at higher weight losses (about 50%), whereas copolyimides were found to be less stable than polyimide from B. Thermal cyclodehydration of polyamic acids to polyimide occurred at lower temperatures in copolymers than the polymer of B.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0021-8995Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: Polyimides were synthesized from 4,4′-diamino diphenyl methane and pyromellitic dianhydride using low-temperature solution polycondensation. Solutions of these polyamic acids in dimethyl-formamide (DMF) were spun into fibers by the wet spinning technique using a mixture of DMF and water as coagulants. Various spinning parameters such as dope concentration, bath composition, and jet stretch were standardized to get polyimide fibers with optimum properties. It was observed that fibers spun at higher jet stretch did not cyclize satisfactorily. Higher dope concentrations gave fibers with better properties. Cyclodehydrated fibers were hot-drawn at 300°C. Fibers with a tenacity of 380 mN/tex, an extension at break of 10%, and initial modulus of 4060 mN/tex were obtained. Mechanical properties of fibers at elevated temperatures, i.e., 100 and 200°C were also measured. Heat aging at 100, 200, and 300°C was carried out for 10 hr. This resulted in an increase in the initial modulus of fibers. However, a 28% decrease in tenacity was observed when the fibers were heat-aged at 300°C. The dynamic thermogravimetry in air showed that fibers were stable up to 400°C. The activation energy of decomposition, calculated from these thermograms in the temperature range 540-610°C was 101 kJ/mole.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesGoel, R. N. ; Hepworth, A. ; Deopura, B. L. ; Varma, I. K. ; Varma, D. S.
New York, NY [u.a.] : Wiley-Blackwell
Published 1979Staff ViewISSN: 0021-8995Keywords: Chemistry ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: Polyimide fibers were prepared by wet spinning of poly(p,p′ -diaminodiphenylmethanepyro-mellitamic acid). Density measurements and x-ray diffraction studies were carried out to study the structure of the resultant polyimide fibers. Polyamic acid as well as undrawn polyimide fibers were essentially amorphous with two amorphous haloes. Hot drawing of the fibers at 300°C resulted in increase in crystallinity, and a simultaneous decrease in density also took place. X-ray data revealed that meridional reflections correspond to the repeat unit length in the fiber. Scanning electron micrography studies indicated that polyamic acid fibers prepared by a wet-spinning technique developed voids during spinning which increased on cyclodehydration to the polyimide state. Hot drawing of fibers resulted in enlargement of these voids. However, a highly fibrillated structure was developed during drawing which could account for the strength of the fibers.Additional Material: 10 Ill.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesRüegg, R. ; Gloor, U. ; Goel, R. N. ; Ryser, G. ; Wiss, O. ; Isler, O.
New York, NY : Wiley-Blackwell
Published 1959Staff ViewISSN: 0018-019XKeywords: Chemistry ; Organic ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Ubiquinone(45) has been synthesized from 5-methyl-2, 3-dimethoxy-hydroquinone and solanesol, which is a C45 isoprenoid alcohol. Chain-lengthening of solanesol by one isoprene unit and condensation with 5-methyl-2, 3-dimethoxy-hydroquinone led to ubiquinone(50). The synthetic ubiquinone(45) proved to be identical with a natural sample from liver of vitamin A deficient rats and synthetic ubiquinone-(50) with a natural sample from pig heart.Additional Material: 3 Ill.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0360-6376Keywords: Physics ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Polyimides with different proportions of m-phenylene and p-phenylene (or p,p′-biphenylene) were prepared by polymerizing different molar ratios of m-phenylene diamine and p-phenylene diamine (or p,p′-diaminobiphenyl) with pyromellitic dianhydride in dimethylformamide at 0°C. Chemical cyclodehydration of polyamic acids resulted in the corresponding polyimides. Polymers were characterized by infrared (IR), viscosity, and density measurements. Viscosity and density of polymers decreased with an increase on m-phenylene groups in the backbone. The thermal and thermooxidative stabilities were investigated by dynamic thermogravimetry. Stability decreased when m-phenylene groups were introduced in the backbone.Additional Material: 6 Ill.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 0377-0486Keywords: Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyPhysicsNotes: The infrared and Raman spectra of liquid 2, 4-dimethoxypyrimidine and solid 6-chloro-2,4-dimethoxypyrimidine and the near ultraviolet spectra of their vapours are reported. An assignment of fundamentals is proposed. Spectra in polar solvents in the UV region are also reported and the effect of solvents is discussed.Additional Material: 5 Ill.Type of Medium: Electronic ResourceURL: