Search Results - (Author, Cooperation:R. Fonseca)
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1Staff View
Publication Date: 2018-03-16Publisher: American Chemical Society (ACS)Topics: Chemistry and PharmacologyPublished by: -
2N. A. Fontana; R. Fonseca-Maldonado; L. F. S Mendes; L. P. Meleiro; A. J. Costa-Filho
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-10-25Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2045-2322Topics: Natural Sciences in GeneralPublished by: -
3M. A. Chapman ; M. S. Lawrence ; J. J. Keats ; K. Cibulskis ; C. Sougnez ; A. C. Schinzel ; C. L. Harview ; J. P. Brunet ; G. J. Ahmann ; M. Adli ; K. C. Anderson ; K. G. Ardlie ; D. Auclair ; A. Baker ; P. L. Bergsagel ; B. E. Bernstein ; Y. Drier ; R. Fonseca ; S. B. Gabriel ; C. C. Hofmeister ; S. Jagannath ; A. J. Jakubowiak ; A. Krishnan ; J. Levy ; T. Liefeld ; S. Lonial ; S. Mahan ; B. Mfuko ; S. Monti ; L. M. Perkins ; R. Onofrio ; T. J. Pugh ; S. V. Rajkumar ; A. H. Ramos ; D. S. Siegel ; A. Sivachenko ; A. K. Stewart ; S. Trudel ; R. Vij ; D. Voet ; W. Winckler ; T. Zimmerman ; J. Carpten ; J. Trent ; W. C. Hahn ; L. A. Garraway ; M. Meyerson ; E. S. Lander ; G. Getz ; T. R. Golub
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Blood Coagulation/genetics ; CpG Islands/genetics ; DNA Mutational Analysis ; DNA Repair/genetics ; Exons/genetics ; Exosome Multienzyme Ribonuclease Complex ; Genome, Human/*genetics ; Genomics ; Histones/metabolism ; Homeodomain Proteins/genetics ; Homeostasis/genetics ; Humans ; Methylation ; Models, Molecular ; Molecular Sequence Data ; Multiple Myeloma/drug therapy/enzymology/*genetics/metabolism ; Mutation/*genetics ; NF-kappa B/metabolism ; Oncogenes/genetics ; Open Reading Frames/genetics ; Protein Biosynthesis/genetics ; Protein Conformation ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors/genetics/metabolism ; RNA Processing, Post-Transcriptional/genetics ; Ribonucleases/chemistry/genetics ; Signal Transduction/genetics ; Transcription, Genetic/geneticsPublished by: -
4Staff View
Publication Date: 2018-03-06Publisher: Oxford University PressPrint ISSN: 1525-2167Electronic ISSN: 1532-2114Topics: MedicinePublished by: -
5Ren, C. ; Duda, B. J. ; Evans, R. G. ; Fonseca, R. A. ; Hemker, R. G. ; Mori, W. B.
[S.l.] : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The nonlinear interaction between light beams in a plasma is studied. In particular, nonlinearities due to relativistic mass corrections and density modulations from a plasma wave wake are considered; but the results can be generalized for other nonlinearities. A simple physical picture using the nonlinear phase velocity of the light wave in a plasma is developed to show that when two laser beams are coherent, the force can be repulsive or attractive, depending on their relative phase. When the two laser beams are polarized in mutually perpendicular directions, the force is always attractive. Using a variational method, a simple analytical expression for this attractive force is derived for Gaussian beams. The centers of the lasers move analogously to point masses under this attractive force with the laser power playing the role of the mass. Under an attractive force, solutions exist where the two lasers can spiral around each other. It is also shown that the plasma wave wake can cause the two spiraling lasers to become intertwined forming a braided pattern. The braiding is common to any nonlinearity which is not instantaneous. The analytical results concerning attraction, repulsion, and braiding have been confirmed using three dimensional particle-in-cell simulations. The simulations also show that angular momentum can radiate away leading to the coalescence of the remaining energy. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
6Tomás, A. R. ; Praça, M. J. ; Fonseca, R. ; André, S. ; Mendonça, E.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2303Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Determination of HER-2 status is an essential prerequisite in considering a patient's eligibility for anti-HER-2 therapy; few studies have focused on its evaluation on cytological material. We present a new method of assessing HER-2 status on cytological samples, by fluorescence in situ hybridization (FISH) with an automated detection system, using fresh frozen (FF) and May–Grünwald–Giemsa (MGG) stained smears, and we evaluate the reliability of HER-2 determination on fine needle aspiration cytology (FNAC). The pre-treatment protocol for FF smears is easier and faster than for MGG stained slides. However, with the described procedure, FISH is also feasible on archival MGG stained slides. We conclude that with this method, cytological samples obtained by FNAC, either FF or MGG, are a reliable option for assessing HER-2 status.Type of Medium: Electronic ResourceURL: -
7Stieglitz, H. ; Cervantes, L. ; Robledo, R. ; Fonseca, R. ; Covarrubias, L. ; Bolivar, F. ; Kupersztoch, Y.M.
Amsterdam : ElsevierStaff ViewISSN: 0147-619XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
8Fonseca, R. G. ; Dos Santos Cruz, C. A. ; Adabo, G. L. ; Vaz, L. G.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-2842Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: summary The limitation of photoactivation of dual-polymerized resin cements along the margins of metal restorations may adversely affect the mechanical properties of these cements, thus impairing the retention of restorations. The aim of this study was to assess the bond strength of cast metal crowns cemented with three dual-polymerized resin cements, using a chemically-activated resin cement and zinc phosphate as controls. Fifty nickel–chromium alloy crowns were cast and randomly assigned to five groups of equal size. Castings were cemented on their corresponding metal dies with one of the tested luting agents: Scotchbond Resin Cement, Enforce and Panavia F (dual-polymerized resin cements), Cement-It (chemically-activated resin cement) and Zinc Phosphate Cement (zinc phosphate cement). Specimens were stored in distilled water at 37 °C for 24 h and then loaded in tension until failure. Panavia F and Zinc Phosphate Cement provided the highest and lowest bond strength means, respectively. Scotchbond Resin Cement, Enforce and Cement-It cements exhibited similar intermediate values, but with statistically significant difference compared to the other materials (P 〈 0·05). Even with the restriction or absence of light activation, all tested dual-polymerized resin cements produced significantly higher bond strength than did the zinc phosphate cement and yielded similar or better results than the chemically activated cement. It should be pointed out that the findings of this study relate to a test scenario which does not mimic clinical circumstances and that further work is required to identify the clinical significance of the reported tensile bond strength differences between the different luting materials.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0003-9861Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0048-721XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Theology and Religious StudiesType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1573-4994Keywords: Insulators ; crystal and ligand fields ; elpasolite ; chromium ; time-resolved optical spectroscopySource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract Interest in 3d transition metal impurities in ionic crystals has increased due to their important role in the laser activity of these materials. Moreover, recent advances in tunable solid-state lasers and high-power semiconductor laser diode arrays have generated a strong interest in investigating new compounds that emit in the visible and near-infrared spectral regions. In particular, many optical studies have been devoted to Cr3+-doped fluoride crystals as a consequence of the high quality of some Cr3+-based laser materials. In the present investigation, the low-temperature emission spectra of Cr3+ ions in the hexagonal elpasolites Cs2NaAlF6 and Cs2NaGaF6 have been measured. Each compound has two crystallographically inequivalent octahedral sites for the Al3+ and Ga3+ ions that can be occupied by Cr3+ ions. For both materials, the luminescence spectrum presents two zero-phonon lines accompanied by a well-defined vibrational structure. The different peaks of the emission broad band are described in terms of phonons of the lattice and normal modes of the octahedral complex [CrF6]3−. A detailed analysis of the vibrational structure observed leads to the conclusion that the 2 E and 4 T 2 excited states of the [CrF6]3− ion are displaced along the e g and a 1g and probably the t 2g coordinates.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1434-4726Keywords: Chondrosarcoma ; Laryngeal neoplasmsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Chondrosarcoma of the larynx is a rare, slow-growing malignant tumor. One hundred and fifty cases of this entity have been reported in the literature. In 75% of cases the site of involvement was the cricoid cartilage, while 20% have involved the thyroid cartilage. The tumor presents as a space-occupying lesion in the subglottic region, or as a neck mass. An insidious, slowly progressing disease course associated with hoarseness and dyspnea accounts for usual delays in arriving at a diagnosis. We report our experiences with six cases of this entity and discuss a diagnostic and therapeutic approach. Whenever possible a conservative surgical management should be attempted.Type of Medium: Electronic ResourceURL: -
13Fonseca, R. J. M. ; Saurel, J. M. ; Foucaran, A. ; Camassel, J. ; Massone, E. ; Taliercio, T. ; Boumaiza, Y.
Springer
Published 1995Staff ViewISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Porous silicon (PS) layers are formed on p+ -type silicon wafers by electrochemical anodization in hydrofluoric acid solutions. Microechography and acoustic signature, V(z), have been performed at 1.5 GHz and 600 MHz, respectively, in order to study the elastic properties of PS layers. The thicknesses of PS layers were measured and longitudinal, shear and Rayleigh velocities and Young's modulus were obtained as a function of porosity. Equations showing the porosity dependence of bulk wave velocities and Young's modulus have also been proposed.Type of Medium: Electronic ResourceURL: -
14Gutiérrez-Ortiz, J.I. ; López-Fonseca, R. ; González-Ortiz de Elguea, C. ; González-Marcos, M.P. ; González-Velasco, J.R.
Springer
Published 2000Staff ViewISSN: 1588-2837Keywords: Catalytic hydrogenation ; mass transfer ; methyl oleateSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract A detailed mass transfer analysis was developed both theoretically and experimentally for the heterogeneously catalyzed hydrogenation of methyl oleate using a Ni/silica catalyst in a slurry reactor. The results indicate that, at the conditions studied, working with stirring rate between 1400 and 2000 rpm, catalyst particle size below 50 µm, and catalyst weight below 1.11 g assured the kinetic regime for the reaction.Type of Medium: Electronic ResourceURL: