Search Results - (Author, Cooperation:R. F. Smith)

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  1. 1
  2. 2
    Staff View
    Publication Date:
    2014-07-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    R. S. McWilliams ; D. K. Spaulding ; J. H. Eggert ; P. M. Celliers ; D. G. Hicks ; R. F. Smith ; G. W. Collins ; R. Jeanloz
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-11-28
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2018-04-26
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Electronic ISSN:
    2375-2548
    Topics:
    Natural Sciences in General
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Smith, R. F. ; French, N. P. ; Saphier, P. W. ; Lowry, P. J. ; Veldhuis, J. D. ; Dobson, H.

    Oxford, UK : Blackwell Science, Ltd
    Published 2003
    Staff View
    ISSN:
    1365-2826
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    This study used the novel approach of statistical modelling to investigate the control of hypothalamic-pituitary-adrenal (HPA) axis and quantify temporal relationships between hormones. Two experimental paradigms were chosen, insulin-induced hypoglycaemia and 2 h transport, to assess differences in control between noncognitive and cognitive stimuli. Vasopressin and corticotropin-releasing hormone (CRH) were measured in hypophysial portal plasma, and adrenocorticotropin hormone (ACTH) and cortisol in jugular plasma of conscious sheep, and deconvolution analysis was used to calculate secretory rates, before modelling. During hypoglycaemia, the relationship between plasma glucose and vasopressin or CRH was best described by log10 transforming variables (i.e. a positive power–curve relationship). A negative-feedback relationship with log10 cortisol concentration 2 h previously was detected. Analysis of the ‘transport’ stimulus suggested that the strength of the perceived stimulus decreased over time after accounting for cortisol facilitation and negative-feedback. The time course of vasopressin and CRH responses to each stimulus were different However, at the pituitary level, the data suggested that log10 ACTH secretion rate was related to log10 vasopressin and CRH concentrations with very similar regression coefficients and an identical ratio of actions (2.3 : 1) for both stimuli. Similar magnitude negative-feedback effects of log10 cortisol at −110 min (hypoglycaemia) or −40 min (transport) were detected, and both models contained a stimulatory relationship with cortisol at 0 min (facilitation). At adrenal gland level, cortisol secretory rates were related to simultaneously measured untransformed ACTH concentration but the regression coefficient for the hypoglycaemia model was 2.5-fold greater than for transport. No individual sustained maximum cortisol secretion for longer than 20 min during hypoglycaemia and 40 min during transport. These unique models demonstrate that corticosteroid negative-feedback is a significant control mechanism at both the pituitary and hypothalamus. The amplitude of HPA response may be related to stimulus intensity and corticosteroid negative-feedback, while duration depended on feedback alone.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Warren-Smith, R. F. ; Scarrott, S. M. ; Murdin, Paul

    [s.l.] : Nature Publishing Group
    Published 1981
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Low resolution (50 A) spectra2 of the Red Rectangle show a blue continuum spectrum identical to that of the central star, plus a broad red emission feature which extends over 2,100 A and is centred near 6,400 A. From polarization measurements3'4 it is clear that, while the blue spectrum is ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    TOOSEY, R. D. ; SMITH, R. F. Y.

    [s.l.] : Nature Publishing Group
    Published 1964
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] In 1961 an initial experiment was begun to examine the influence of plant density and level of nitrogenous fertilizer on the growth and yield of Cannell's marrow stem kale. Four spacings, unsingled (Px) and plants singled to mean spacings of 6 (P2), 12 (P8) and 18 (P4) in., that is, 14-1, 6, 3 and ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    SMITH, R. F.

    [s.l.] : Nature Publishing Group
    Published 1963
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] These results, which vary from 0-160 to 0-400 nig/g, are of the same order as the previously published values for roasted coffee2-5, and Carvalho has since informed me that they were in fact made after the samples had been roasted in a small electric roaster, to an intensity a little less than that ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Rackow, E. ; Kittner, P. W. ; Smith, R. F.
    Springer
    Published 1974
    Staff View
    ISSN:
    1438-2385
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1573-0832
    Keywords:
    yeasts ; incidence of burned patients ; nystatin therapy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract The incidence of yeasts in the oral cavity, rectum and urine of a population of 60 children hospitalized for treatment of acute second and third degree burns was approximately the same at the time of their admission as would be expected in healthy subjects. After hospitalization, the incidence of yeasts was reduced in the intestinal tract of acute patients who received nystatin orally but increased in the oral cavity. The majority of 418 yeasts were inhibited in vitro by less than 50 units/ml nystatin and only 6 yeasts were resistant to more than 3.1 μg/ml amphotericin B. The oral cavity appeared to act as a significant reservoir from which yeasts spread to cause or contribute to the deaths of 2 of 5 patients who died during the study.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Smith, R. F. 〈SJ〉

    Woodstock, Md., etc : Periodicals Archive Online (PAO)
    Published 1957
    Articles: DFG German National Licenses
  12. 12
    Smith, R. F. 〈SJ〉

    Woodstock, Md., etc : Periodicals Archive Online (PAO)
    Published 1958
    Articles: DFG German National Licenses
  13. 13
    Smith, R. F. 〈SJ〉

    Woodstock, Md., etc : Periodicals Archive Online (PAO)
    Published 1953
    Staff View
    ISSN:
    0040-5639
    Topics:
    Theology and Religious Studies
    Notes:
    DESCRIPTIVE NOTICES
    URL:
    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    1432-0428
    Keywords:
    Chlorpropamide-alcohol flushing ; chlorpropamide ; alcohol ; flushing ; body temperature ; diabetes
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Forty-three diabetic patients on maintenance chlorpropamide (100–750 mg daily) drank 0.2 ml/kg 90% ethanol after equilibration in a room controlled at 20° C. Twenty-five patients had already noted marked alcohol flushing since starting chlopropamide therapy (group A), while 13 had not observed this (group B). The remainder were teetotal or unsure of their reaction. Cheek temperature rise correlated with plasma chlorpropamide concentration (r=0.6, p〈0.001) in all patients and was inversely related to basal cheek temperature (r=-0.35, p〈0.02). Plasma chlorpropamide correlated with daily chlorpropamide dose (r=0.8, p〈0.001) but not with basal cheek temperature. The correlation between chlorpropamide level and cheek temperature rise was strengthened on analysis of group A alone (r=0.7, p〈0.001) and absent in group B (r=0.2, p〉0.3) who tended to have lower chlorpropamide levels and cheek temperature rise than group A.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    1432-0428
    Keywords:
    Insulin ; C-peptide ; radio-immunoassay ; haemolysis
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Venous blood was taken at the end of a glucose infusion test in 19 individuals and divided into four aliquots, 3 of which were variably haemolysed by repeated passage through a 23-gauge needle to simulate traumatic venepuncture. Plasma insulin (measured by both a charcoal separation and a double-antibody method), C-peptide, and haemoglobin were measured in each aliquot, and haemolysis was also assessed visibly. A significant loss of immuno-assayable plasma insulin was found in samples with only a trace of visible haemolysis, with up to 90% lost in severely haemolysed samples. Plasma C-peptide was unaffected by haemolysis. This represents an additional advantage for the use of plasma C-peptide in assessing insulin secretion.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  16. 16
    Lewis, I. D. ; Smith, R. F. ; Knott, J. F.
    Springer
    Published 1975
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    King, J. E. ; Smith, R. F. ; Knott, J. F.
    Springer
    Published 1978
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    King, J. E. ; Smith, R. F. ; Knott, J. F.
    Springer
    Published 1977
    Staff View
    ISSN:
    1573-2673
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Seifert, B. ; R.H.S. ; Smith, R. F. ; Jancik, F.
    Springer
    Published 1983
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    1618-2650
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses