Search Results - (Author, Cooperation:R. Elango)
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1N. Saini ; S. Ramakrishnan ; R. Elango ; S. Ayyar ; Y. Zhang ; A. Deem ; G. Ira ; J. E. Haber ; K. S. Lobachev ; A. Malkova
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-09-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: *Chromosome Breakage ; *DNA Breaks, Double-Stranded ; DNA Helicases/metabolism ; DNA Repair/genetics ; DNA Replication/*genetics ; DNA, Fungal/*biosynthesis/genetics ; Genomic Instability/genetics ; Mutagenesis/genetics ; S Phase/genetics ; Saccharomyces cerevisiae/cytology/enzymology/*genetics/metabolism ; Saccharomyces cerevisiae Proteins/metabolismPublished by: -
2Staff View
ISSN: 1432-1777Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract. We describe here a set of genetic markers, based on IRS–PCR amplification difference, that are specifically designed for efficient, high throughput genetic mapping in [(M. domesticus× wild-derived) F1×M. domesticus] interspecific backcrosses. 146 new genetic loci have been mapped, and strain distribution for these markers has been determined in 96 mouse strains. 103 (81%) of 127 tested markers are present only in one or more wild-derived strains, but absent in 76 other commonly used strains, demonstrating their utility in a variety of mouse pair combinations. Because of the ease of genotyping with this marker set, rapid genome scans for complex genetic trait loci involving crosses between wild-derived strains and other commonly used strains can now be carried out efficiently with large numbers of animals.Type of Medium: Electronic ResourceURL: