Search Results - (Author, Cooperation:R. E. Lenski)

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  1. 1
    A. I. Khan ; D. M. Dinh ; D. Schneider ; R. E. Lenski ; T. F. Cooper
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-06-04
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Adaptation, Physiological ; *Biological Evolution ; *Epistasis, Genetic ; Escherichia coli/*genetics/physiology ; Evolution, Molecular ; Genes, Bacterial ; *Genetic Fitness ; Genome, Bacterial ; Genotype ; Models, Genetic ; *Mutation ; Selection, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    J. R. Meyer ; D. T. Dobias ; J. S. Weitz ; J. E. Barrick ; R. T. Quick ; R. E. Lenski
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-01-28
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; Bacterial Outer Membrane Proteins/genetics/*metabolism ; Bacteriophage lambda/*genetics/physiology ; Escherichia coli/genetics/metabolism/*virology ; *Evolution, Molecular ; Genome, Bacterial ; Genome, Viral ; *Mutation ; Polymorphism, Single Nucleotide ; Porins/genetics/*metabolism ; Receptors, Virus/genetics/*metabolism ; Selection, Genetic ; Viral Tail Proteins/chemistry/*genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-10-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adaptation, Physiological/genetics ; Animals ; *Biological Evolution ; *Developmental Biology/trends ; Ecosystem ; Epigenesis, Genetic ; *Gene-Environment Interaction ; Genetic Speciation ; *Models, Biological ; Models, Genetic ; Phenotype ; Reproducibility of Results ; Selection, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    R. J. Woods ; J. E. Barrick ; T. F. Cooper ; U. Shrestha ; M. R. Kauth ; R. E. Lenski
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-03-19
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Adaptation, Physiological ; *Biological Evolution ; Epistasis, Genetic ; Escherichia coli/*genetics/*physiology ; Genes, Bacterial ; *Genetic Fitness ; Genotype ; Models, Genetic ; *Mutation ; *Selection, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    J. Plucain ; T. Hindre ; M. Le Gac ; O. Tenaillon ; S. Cruveiller ; C. Medigue ; N. Leiby ; W. R. Harcombe ; C. J. Marx ; R. E. Lenski ; D. Schneider
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-03-08
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; *Epistasis, Genetic ; Escherichia coli/*genetics/metabolism/*physiology ; Evolution, Molecular ; Genes, Bacterial ; Genes, Regulator ; Genetic Fitness ; Genotype ; Glucose/metabolism ; Microbial Interactions ; *Mutation ; *Polymorphism, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    M. J. Wiser ; N. Ribeck ; R. E. Lenski
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-11-16
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Adaptation, Physiological ; Escherichia coli/*genetics/*physiology ; *Genetic Fitness ; Models, Biological ; *Reproduction, Asexual
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Z. D. Blount ; J. E. Barrick ; C. J. Davidson ; R. E. Lenski
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-09-21
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Aerobiosis/genetics ; Citric Acid/*metabolism/pharmacology ; DNA Mutational Analysis ; Epistasis, Genetic ; Escherichia coli/drug effects/*genetics/*metabolism ; Escherichia coli Proteins/genetics/metabolism ; *Evolution, Molecular ; Gene Expression Regulation, Bacterial/genetics ; Genome, Bacterial/*genetics ; *Genomics ; Glucose/deficiency/metabolism/pharmacology ; Models, Genetic ; Organic Anion Transporters/genetics/metabolism ; Phenotype ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Blount, Z. D., Lenski, R. E., Losos, J. B.
    American Association for the Advancement of Science (AAAS)
    Published 2018
    Staff View
    Publication Date:
    2018-11-09
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Evolution, Online Only
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Lenski, R. E.
    Springer
    Published 1993
    Staff View
    ISSN:
    1420-9071
    Keywords:
    Genetically modified microorganisms ; competitive fitness ; environmental effects ; genomic coadaptation ; energetic inefficiency ; domestication
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract Genetically modified microorganisms hold great promise for environmental applications. Nonetheless, some may have unintended adverse effects. Of particular concern for risk assessment is the simple fact that microorganisms are self-replicating entities, so that it may be impossible to control an adverse effect simply by discontinuing further releases of the organism. It has been suggested, however, that genetically modified microorganisms will be poor competitors and therefore unable to persist in the wild due to energetic inefficiency, disruption of genomic coadaptation, or domestication. Many studies support the hypothesis that genetically modified microorganisms are less fit than their progenitors, but there are a few noteworthy counter-examples in which genetic modifications unexpectedly enhance competitive fitness. Furthermore, subsequent evolution may eliminate the maladaptive effects of some genes, increasing the likelihood that a modified organism or its engineered genes will persist. Evaluating the likelihood that a genetically modified microorganism or its engineered genes will persist is a complex ecological and evolutionary problem. Therefore, an efficient regulatory framework would require such evaluations only when there are plausible scenarios for significant adverse environmental effects.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses