Search Results - (Author, Cooperation:R. E. Lenski)
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1A. I. Khan ; D. M. Dinh ; D. Schneider ; R. E. Lenski ; T. F. Cooper
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-06-04Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Adaptation, Physiological ; *Biological Evolution ; *Epistasis, Genetic ; Escherichia coli/*genetics/physiology ; Evolution, Molecular ; Genes, Bacterial ; *Genetic Fitness ; Genome, Bacterial ; Genotype ; Models, Genetic ; *Mutation ; Selection, GeneticPublished by: -
2J. R. Meyer ; D. T. Dobias ; J. S. Weitz ; J. E. Barrick ; R. T. Quick ; R. E. Lenski
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-01-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Bacterial Outer Membrane Proteins/genetics/*metabolism ; Bacteriophage lambda/*genetics/physiology ; Escherichia coli/genetics/metabolism/*virology ; *Evolution, Molecular ; Genome, Bacterial ; Genome, Viral ; *Mutation ; Polymorphism, Single Nucleotide ; Porins/genetics/*metabolism ; Receptors, Virus/genetics/*metabolism ; Selection, Genetic ; Viral Tail Proteins/chemistry/*genetics/metabolismPublished by: -
3K. Laland ; T. Uller ; M. Feldman ; K. Sterelny ; G. B. Muller ; A. Moczek ; E. Jablonka ; J. Odling-Smee ; G. A. Wray ; H. E. Hoekstra ; D. J. Futuyma ; R. E. Lenski ; T. F. Mackay ; D. Schluter ; J. E. Strassmann
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-10-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological/genetics ; Animals ; *Biological Evolution ; *Developmental Biology/trends ; Ecosystem ; Epigenesis, Genetic ; *Gene-Environment Interaction ; Genetic Speciation ; *Models, Biological ; Models, Genetic ; Phenotype ; Reproducibility of Results ; Selection, GeneticPublished by: -
4R. J. Woods ; J. E. Barrick ; T. F. Cooper ; U. Shrestha ; M. R. Kauth ; R. E. Lenski
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-03-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Adaptation, Physiological ; *Biological Evolution ; Epistasis, Genetic ; Escherichia coli/*genetics/*physiology ; Genes, Bacterial ; *Genetic Fitness ; Genotype ; Models, Genetic ; *Mutation ; *Selection, GeneticPublished by: -
5J. Plucain ; T. Hindre ; M. Le Gac ; O. Tenaillon ; S. Cruveiller ; C. Medigue ; N. Leiby ; W. R. Harcombe ; C. J. Marx ; R. E. Lenski ; D. Schneider
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-08Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; *Epistasis, Genetic ; Escherichia coli/*genetics/metabolism/*physiology ; Evolution, Molecular ; Genes, Bacterial ; Genes, Regulator ; Genetic Fitness ; Genotype ; Glucose/metabolism ; Microbial Interactions ; *Mutation ; *Polymorphism, GeneticPublished by: -
6M. J. Wiser ; N. Ribeck ; R. E. Lenski
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-11-16Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Adaptation, Physiological ; Escherichia coli/*genetics/*physiology ; *Genetic Fitness ; Models, Biological ; *Reproduction, AsexualPublished by: -
7Z. D. Blount ; J. E. Barrick ; C. J. Davidson ; R. E. Lenski
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-21Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Aerobiosis/genetics ; Citric Acid/*metabolism/pharmacology ; DNA Mutational Analysis ; Epistasis, Genetic ; Escherichia coli/drug effects/*genetics/*metabolism ; Escherichia coli Proteins/genetics/metabolism ; *Evolution, Molecular ; Gene Expression Regulation, Bacterial/genetics ; Genome, Bacterial/*genetics ; *Genomics ; Glucose/deficiency/metabolism/pharmacology ; Models, Genetic ; Organic Anion Transporters/genetics/metabolism ; Phenotype ; Phylogeny ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/geneticsPublished by: -
8Blount, Z. D., Lenski, R. E., Losos, J. B.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-11-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Evolution, Online OnlyPublished by: -
9Staff View
ISSN: 1420-9071Keywords: Genetically modified microorganisms ; competitive fitness ; environmental effects ; genomic coadaptation ; energetic inefficiency ; domesticationSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Genetically modified microorganisms hold great promise for environmental applications. Nonetheless, some may have unintended adverse effects. Of particular concern for risk assessment is the simple fact that microorganisms are self-replicating entities, so that it may be impossible to control an adverse effect simply by discontinuing further releases of the organism. It has been suggested, however, that genetically modified microorganisms will be poor competitors and therefore unable to persist in the wild due to energetic inefficiency, disruption of genomic coadaptation, or domestication. Many studies support the hypothesis that genetically modified microorganisms are less fit than their progenitors, but there are a few noteworthy counter-examples in which genetic modifications unexpectedly enhance competitive fitness. Furthermore, subsequent evolution may eliminate the maladaptive effects of some genes, increasing the likelihood that a modified organism or its engineered genes will persist. Evaluating the likelihood that a genetically modified microorganism or its engineered genes will persist is a complex ecological and evolutionary problem. Therefore, an efficient regulatory framework would require such evaluations only when there are plausible scenarios for significant adverse environmental effects.Type of Medium: Electronic ResourceURL: