Search Results - (Author, Cooperation:R. E. Hernandez)

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  1. 1
    C. J. Cambier ; K. K. Takaki ; R. P. Larson ; R. E. Hernandez ; D. M. Tobin ; K. B. Urdahl ; C. L. Cosma ; L. Ramakrishnan
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-12-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Female ; Glycolipids/immunology/metabolism ; *Immune Evasion ; Lipids/biosynthesis/immunology ; Macrophages/cytology/immunology/metabolism/*microbiology ; Membrane Lipids/*metabolism ; Mice ; Mice, Inbred C57BL ; Mycobacterium/pathogenicity/*physiology ; Mycobacterium tuberculosis/pathogenicity/physiology ; Receptors, CCR2/metabolism ; Toll-Like Receptors/immunology/metabolism ; Virulence/immunology ; Zebrafish/microbiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1432-0428
    Keywords:
    Insulin secretion ; B cell ultrastructure ; calcium distribution ; pyroantimonate ; pancreas perfusion
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Localization and quantification of calcium pyroantimonate precipitates within the B cells, and determination of insulin secretion were performed in rat pancreas perfused with 3.3 and 16.6 mmol/l glucose. Observations were carried out during the peak, the refractory period, and at 10 and 20 min in the second phase of glucose secretion after the start of a glucose challenge. Specific calcium pyroantimonate precipitates, assessed by EGTA cross-incubation, appeared attached to plasma membrane, Golgi complex, mitochondria, cytoplasmic matrix and secretory granules. The total number of cellular calcium pyroantimonate precipitates increased with perfusion time, being significantly higher at every time-point with the higher concentration of glucose (16.6 mmol/l) than with the 3.3 mmol/l glucose concentration. Calcium pyroantimonate precipitates showed a progressive increment both in plasma membranes and mitochondria. In the cytoplasmic matrix, B granules and Golgi complex, a sharp increase in the number of precipitates was detected at the refractory period, followed by a continuous decrease until the end of the experiment. These results show that the number of calcium pyroantimonate precipitates, localized in different organelles, changes according to the functional state of B cells. They stress the importance of intracellular readily exchangeable pools as regulators of calcium availability for insulin stimulus-secretion coupling.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00283652

    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1420-9071
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Resumen Se estudió el efecto del isoproterenol (ISO) sobre la secreción de insulina in vitro. Los resultados indican que el ISO es capaz de estimular la secreción de insulina en forma similar a la glucosa en altas concentraciones.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02138716

    Articles: DFG German National Licenses
  4. 4
    Naderi, N. ; Hernández, R. E.
    Springer
    Published 1999
    Staff View
    ISSN:
    0043-7719
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Summary Two types of machines, a conventional planer, and a fixed-knife pressure-bar planer were used to prepare matched specimens of sugar maple wood. After adsorption and desorption, both experiments at 21 °C, the EMC, swelling in all principal directions as well as compliance coefficient in radial compression were measured. Two specimen sizes were used for these expe‐riments. For a given equilibrium moisture content, tangential and radial dimensions were greater after desorption than after adsorption, as previously described. When equilibrium was reached by gaining moisture, the wood was stiffer in radial compression compared to when the equilibrium was reached after losing moisture. The magnitude of this phenomenon, second-order effects of moisture sorption, was slightly affected by the type of planing. These effects on swelling were greater for large specimens prepared by conventional planing compared to fixed-knife pressure-bar planing. Small specimens showed similar magnitudes of this phenomenon with both planing methods. No differences between planing methods were found for the radial compliance coefficient measured on either specimen size. Therefore, the second-order effects of moisture sorption appeared to be a bulk phenomenon and not restricted to the superficial layers of wood.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002260050110

    Articles: DFG German National Licenses