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1Latest Papers from Table of Contents or Articles in PressRoberts, B. S., Hardigan, A. A., Moore, D. E., Ramaker, R. C., Jones, A. L., Fitz-Gerald, M. B., Cooper, G. M., Wilcox, C. M., Kimberly, R. P., Myers, R. M.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-05-02Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressA. A. Myburg ; D. Grattapaglia ; G. A. Tuskan ; U. Hellsten ; R. D. Hayes ; J. Grimwood ; J. Jenkins ; E. Lindquist ; H. Tice ; D. Bauer ; D. M. Goodstein ; I. Dubchak ; A. Poliakov ; E. Mizrachi ; A. R. Kullan ; S. G. Hussey ; D. Pinard ; K. van der Merwe ; P. Singh ; I. van Jaarsveld ; O. B. Silva-Junior ; R. C. Togawa ; M. R. Pappas ; D. A. Faria ; C. P. Sansaloni ; C. D. Petroli ; X. Yang ; P. Ranjan ; T. J. Tschaplinski ; C. Y. Ye ; T. Li ; L. Sterck ; K. Vanneste ; F. Murat ; M. Soler ; H. S. Clemente ; N. Saidi ; H. Cassan-Wang ; C. Dunand ; C. A. Hefer ; E. Bornberg-Bauer ; A. R. Kersting ; K. Vining ; V. Amarasinghe ; M. Ranik ; S. Naithani ; J. Elser ; A. E. Boyd ; A. Liston ; J. W. Spatafora ; P. Dharmwardhana ; R. Raja ; C. Sullivan ; E. Romanel ; M. Alves-Ferreira ; C. Kulheim ; W. Foley ; V. Carocha ; J. Paiva ; D. Kudrna ; S. H. Brommonschenkel ; G. Pasquali ; M. Byrne ; P. Rigault ; J. Tibbits ; A. Spokevicius ; R. C. Jones ; D. A. Steane ; R. E. Vaillancourt ; B. M. Potts ; F. Joubert ; K. Barry ; G. J. Pappas ; S. H. Strauss ; P. Jaiswal ; J. Grima-Pettenati ; J. Salse ; Y. Van de Peer ; D. S. Rokhsar ; J. Schmutz
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-06-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Eucalyptus/classification/*genetics ; Evolution, Molecular ; Genetic Variation ; *Genome, Plant ; Inbreeding ; PhylogenyPublished by: -
3Articles: DFG German National LicensesNUTE, G. R. ; JONES, R. C. D. ; DRANSFIELD, E. ; WHELEHAN, O. P.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1365-2621Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Fifty-two ham samples were assessed by a trained panel of ten assessors for appearance, texture and flavour using twenty-two descriptive and three hedonic scales. Generalized Procrustes analysis was used to reveal the spatial configuration of the samples, taking account of differences between individual assessors. The first principal axis accounted for 33% of the overall variation and was related to ‘plastic’ and gelatinous appearance, and firm texture. The second principle axis accounted for 17% of the variation and was related to rubbery, firm, plastic and cohesive texture descriptors, and plastic appearance. The third principal axis accounted for 10% of the variation and was related to the appearance and flavour of the product with dominant colour, fatness and saltiness prominent. The mechanical properties were characterized as shear strength, tensile strength and by a model of visco-elasticity. Firmness increased with shear strength and the gelatinous, plastic appearance was related to the amount of bound water. Cohesiveness and rubberiness increased with ultimate tensile strength and total water content. The equilibrium modulus and principal relaxation times characterized the first two principal axes and gave a good indication of the texture of the products. Ninety-one per cent of the variation in the combined overall hedonic scores was accounted for by the first principal axis—the preferred ham having a firmer, meaty texture. Shear strength and bound moisture were the two best single mechanical indices of this overall liking.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1365-2621Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: A puncture test for measuring the firmness of backfat is described for use in studies of the effects of changes in animal production, and meat processing on the quality of fatty tissue. The operating and recording conditions were chosen from sensory deformation characteristics used in firmness evaluation when pressing fat with the index finger. On average, assessors exerted aaaximum force of about 30 N and caused a deformation of 4 mm in 2 sec and the best predictor of firmness was the maximum deformation they applied. Mechanical properties of the fats were determined by stress relaxation and the modulus 2.5 sec after compression was about 80 × 104 for hard and 〈 3 × 104 N/m2 for soft fat at 3°C and the logarithm of the modulus was linearly related to the subjective firmness rating.In the puncture test, the forces required to drive a stainless steel punch (3.5 mm in diameter) 2.5 or 4.0 mm into backfat at 3°C at 2 mm/sec correlated well (r 〉 0.8) with firmness rating and five replicate determinations using the punch proved more discriminating than a panel of four assessors. A combination of the forces required on inner and outer layers of fat accounted for 93% of variation in firmness assessments.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Techniques for semen storage and artificial insemination of animals have developed considerably during the past twenty-five years but biological, social and economic factors are still limiting the full development of this ...Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesGreenspan, G. ; Rees, R. W. A. ; Link, G. D. ; Boyd, C. P. ; Jones, R. C. ; Alburn, H. E.
Springer
Published 1974Staff ViewISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Zusammenfassung Die mikrobiologische 1β-Hydroxylierung vond-Norgestrel und Norethisteron durch den MikroorganismusBotryodiplodia malorum wird beschrieben. Ausserdem wurde 11β-Hydroxynorethisteron isoliert und charakterisiert.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1432-0614Source: Springer Online Journal Archives 1860-2000Topics: BiologyProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Summary Equations are described which relate nutrient feed rate to specific microbial growth rate in fed batch culture. Fed batch cultures are classified into three types: 1) those allowing constant specific microbial growth rate, 2) those in which the rate of change of flow rate is constant and 3) those in which the nutrient flow rate is constant. The basic properties of these three types are described.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Mature bull elephants, 15 to 50 yr old, were immobilized by shooting with darts that injected ?Scoline? (Glaxo Laboratories Ltd) on impact, then bled from the jugular vein and eviscerated. The reproductive tract was removed within 15 min of death and the excurrent duct of the testis dissected. ...Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Eleven compounds, within hollow capsules of polydimethylsiloxane (Silastic®), have been studied with regard to their rate of release and anti-inflammatory activity in the Adjuvant Arthritic (AA) rat. All of the compounds diffused through the capsule wall to some extent with cortisone acetate exhibiting the slowest and ibuprofen the fastest release rate. Of the eleven encapsulated compounds, only phenylbutazone, indomethacin, ibuprofen and naproxen significantly reduced right and left paw volume below that of control value. Silastic encapsulation increases efficacy of phenylbutazone and indomethacin two to three times over subcutaneous or oral administration. Based on potency and duration of constant release, indomethacin and naproxen should exhibit anti-inflammatory activity in excess of 12 months.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Résumé Le nombre de corps jaunes dans l'ovaire de rates intactes, hémicastrées, hémicastrées et thyroïprivées fut déterminé. Les corps jaunes de l'animal thyroïprivé et hémicastré furent sensiblement plus petits que ceux de l'animal hémicastré. Cette diminution des corps jaunes se traduit par une diminution concomitante du poids ovarien et pourrait expliquer le blocage partiel de l'hypertrophie compensatrice du reste de l'ovaire.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1420-9136Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesPhysicsNotes: Summary A model for ball lightning is presented and its properties discussed. The model is that of a microwave radiation field contained within a plasma dielectric sphere, resonant at a frequency much greater than the electron-molecule collision frequency. Calculations are made of the energy stored in the microwave field, the electron temperature, the rate of energy loss due to ionization, and the effects of recombination. It is concluded (a) that a self-consistent set of conditions can be obtained only when the neutral density within the sphere is much lower than atmospheric, and (b) that the microwave field strength required is of the order of 109V/m. Under these conditions the radiation pressure becomes comparable to that of the atmosphere; the second case investigated is when these two become equal. It is then found that this ‘radiation bubble’ appears to satisfy the requirements imposed on energy storage and dissipation, recombination and resonant frequency. The electron density in such a bubble is found to be typically 1011 cm−3 and the stored energy typically 103 Joules. A discussion is given of some of the problems associated with the model-formation, stability, neutral number density, and the problem of hydrostatic equilibrium.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesCampbell, A. ; Martin, M. K. ; Farrington, K. J. ; Erdelyi, A. ; Johnston, R. ; Sorby, P. ; Whitlock, H. V. ; Pearson, I. G. ; Jones, R. C. ; Haigh, J. A. ; DeGoosh, C. P.
Springer
Published 1967Staff ViewISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Zusammenfassung 2-Acetoxy-4′-chlor-3,5-dijodbenzanilid zeigte eine hohe Wirksamkeit gegen junge und gereifteF. hepatica andH. controtus in Schaften bei einer oralen Dosis von 25 und 40 mg/kg. Die gute Verträglichkeit der Verbindung in Schafen ergab sich aus Feldversuchen in Australien.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1432-1238Keywords: Rat ; Pulmonary artery ; Pulmonary hypertension ; Thromboxane B2 ; Prostacyclin ; Prostaglandin F1α ; EndotoxinSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract To determine in the rat whether pulmonary artery hypertension accompanies thromboxane release, we sequentially monitored pulmonary and systemic artery pressures and cardiac output. We measured pulmonary and aortic plasma levels of TxB2 as well as 6-keto-prostaglandin F1α (6-keto-PGF1α) in awake unrestrained adult male Sprague-Dawley rats given a single infusion of endotoxin at the relatively high dose commonly administered to this endotoxin-resistant species. At 40 min after endotoxin infusion, both pulmonary and aortic TxB2 and 6-keto-PGF1α levels increased nine-fold and seven-fold above baseline, respectively. In the pulmonary artery, 40 min after infusion, both mediator levels differed significantly from baseline (p〈0.05), whereas in the aorta, because of marked variance in the response of different animals, only the 6-keto-PGF1α levels achieved significance (p〈0.05). These changes were associated with a fall in systemic blood pressure and cardiac output, but no demonstrable rise in pulmonary artery pressure (PAP). Despite ultrastructural evidence of vascular injury, these data indicate that in the rat thromboxane and prostacyclin release following a single infusion of endotoxin is not associated with pulmonary hypertension and that increased prostacyclin production may contribute to systemic hypotension.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1432-1238Keywords: Sepsis ; Endotoxemia ; Partitioned resistance ; Reactivity ; Angiotensin II ; Oxygen metabolitesSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Objective: Recurrent episodes of Gram-negative bacteremia (from intraperitoneal abscesses) or endotoxemia cause lung microvascular injury in the rat. Change in vascular reactivity was assessed in response to challenge.Design: In the isolated lung preparation, resistance was partitioned between pre-(PVRa) and post-capillary (PRVv) segments: vasoreactivity was assessed by challenge with Angiotensin II (AII) or reactive oxygen metabolites. Animals received 4 weekly intra-abdominal implants of liveE. coli andB. fragilis in a carrier of sterile cecal content and barium sulfate (SEPSIS) or carrier alone (SHAM SEPSIS): or 4 weekly intravenous infusion ofE. coli endotoxin (ENDO) or of saline (SHAM ENDO). A fifth group were untreated controls (CONTROL).Measurements and results:In the SEPSIS and ENDO lungs, PVRa and PVRv before challenge were normal. In the SEPSIS lung, AII increased PVRa more than in the control lung, PVRv to a similar degree in both. In the ENDO lung it increased PVRa compared with its effect on the SHAM ENDO lung: In both it also increased PVRv, to a similar degree and well above the baseline. Always tachyphylaxis developed with increases in dosage (to 25 μm and 50 μm, respectively). Oxygen free radical challenge in the SEPSIS and ENDO lung caused significant vasoconstriction, particularly PVRv, whereas no response was observed in the CONTROL or SHAM-treated lung from either group.Conclusion: Abnormal lung vascular reativity after SEPSIS or ENDOTOXIN is evident on challenge, the two agents used here detecting site specific changes.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesHughes, C. S. ; Williams, R. A. ; Gaskell, R. M. ; Jordan, F. T. W. ; Bradbury, J. M. ; Bennett, M. ; Jones, R. C.
Springer
Published 1991Staff ViewISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Latency and reactivation of a commercial infectious laryngotracheitis virus vaccine were demonstrated in live chickens. Virus was re-isolated at intervals between seven and fourteen weeks post-vaccination and this may be of epizootiological significance.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1432-0878Keywords: Seminiferous epithelium ; Spermatogonial renewal ; Mitotic activity ; Autoradiography ; 3H-Thymidine incorporation ; Coturnix coturnix japonica (Aves, Phasianiformes)Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary Four different types of spermatogonia were identified in the seminiferous tubules of the Japanese quail: a dark type A (Ad), 2 pale A type (Ap1 and Ap2), and a type B. A model is proposed describing the process of spermatogonial development in the quail. The Ad spermatogonia are considered to be the stem cells. Each divides to produce a new Ad spermatogonium and a Ap1 spermatogonium during Stage IX of the cycle of the seminiferous epithelium. An Ap1 spermatogonium produces two Ap2 spermatogonia during Stage II of the cycle, Ap2 spermatogonia produce four type B spermatogonia during Stage VI of the cycle, and type B spermatogonia produce eight primary spermatocytes during Stage III of the cycle. Consequently, 32 spermatids can result from each division of an Ad spermatogonium. Spermatogonial development in the quail differs from the process described in mammals in that there are fewer mitotic divisions and they are all synchronized with the cycle of the seminiferous epithelium. It is suggested that the fewer mitotic divisions explain why a smaller area of the seminiferous tubule is occupied by a cellular association in the quail than in mammals like the rat, ram and bull. The duration of spermatogenesis from the division of the Ad spermatogonia to sperm release from the seminiferous epithelium was estimated to be 12.77 days.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1432-0878Keywords: Ductuli efferentes ; Stereology ; Fluid transport ; Rat (Wistar)Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Serial sectioning was used to determine the occurrence of ciliated cells, and a morphological technique was used to estimate the relative and absolute surface areas of apical and basolateral membrane of the epithelial cells lining the ductuli efferentes of the rat. It was found that the ciliated cells constitute 15% of the epithelial cells and occur as groups of mainly 1–3 cells which are distributed at random in the duct epithelium. For the non-ciliated cells it was estimated that the formation of microvilli by the apical membrane increased the surface area of that border by a factor of 37-fold. The average surface density of the basolateral membrane was 76% the surface density of the apical membrane. However, there was a 3-fold increase in surface density along the apicalbasal axis of the basolateral plasmalemma. In the Discussion, the ductuli efferentes are compared to their homologue, the proximal tubules of the kidney, in the rates of fluid transport and membrane adaptations of their epithelium.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesSteudel, Wolfgang ; Watanabe, Masazumi ; Dikranian, Krikor ; Jacobson, Margaretha ; Jones, R. C.
Springer
Published 1999Staff ViewISSN: 1432-0878Keywords: Key words Nitric oxide synthase ; Oxygen-induced lung injury ; Pulmonary hypertension ; Rat (Sprague Dawley)Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Breathing air with a high oxygen tension induces an inflammatory response and injures the microvessels of the lung. The resulting development of smooth muscle cells in these segments contributes to changes in vasoreactivity and increased pulmonary artery pressure. This in vivo study determines the temporal and spatial expression of endogenous endothelial nitric oxide synthase (NOS III) and inducible NOS (NOS II), important enzymes regulating vasoreactivity and inflammation, in the adult rat lung during the development of experimental pulmonary hypertension induced by oxidant injury. We analyzed the cellular distribution of these NOS isoforms, using specific antibodies, and assessed enzyme activity at baseline and after 1–28 days of hyperoxia (FIO2 0.87). The number of NOS III-immuno-positive endothelial cells increased early in hyperoxia and then remained high. By day 28, the relative number of these cells had increased from 40% in proximal vessels and 13–16% in distal alveolar vessels of the normal lung to 73–86% and 40–59%, respectively, in hyperoxia. Pulmonary alveolar macrophages (PAMs), normally few in number and only weakly immunopositive for NOS II or III in the normal lung, increased in number in hyperoxia and were strongly immunopositive for each isoform. These morphological data were supported by a temporal increase in total and calcium-independent NOS activity. Thus NOS expression and activity significantly increased in hyperoxia as pulmonary hypertension developed, and NOS III expression increased selectively in vascular endothelial cells, while both NOS isoforms were expressed by the PAM population. We conclude that this increase in expression of a potent vasodilator, an antiproliferative agent for smooth muscle cells, and an antioxidant molecule represents an adaptive response to protect the lung from oxidant-induced vascular and epithelial injury.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1573-5036Keywords: acidity ; aluminium ; calcium ; citrus ; continuous-function design ; legumes ; manganese ; phosphorus ; soil mineral ; sulphur ; variable charge ; weathered soilsSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract Plant-soil interactions in weathered soils are so complex that unqualified statements about a suitable pH for plants are risky. Conventional experimental designs and statistical methods may not be appropriate for investigating such complexities. Lime experiments using continuous function designs and observation of plant response to indigenous variability in soil pH permit detailed observations of plant-soil interactions that are frequently not detected. A graphical boundary-line approach to interpreting data can make good sense out of apparent confusion. Increasing the pH of variable-charge soils by adding lime or by indigenous means increased CEC and retarded cation leaching, but Ca solubility changed very little over the range pH 5 to 6. N fixation and yield was closely related to soil pH, soil Mn and Mn uptake by soybean. This result was clearly demonstrated regardless of numerous other limiting factors. Plant yield response curves resolved into distinct segments that corresponded with associated soil properties. Excess Al compounded by Ca deficiency is suspect in the pH range 〈5. Excess Mn, and Ca deficiency probably limited yields in the pH range 5.0 to 5.7. Yields were stable, and Ca and P were constant in the pH interval 5.7 to 6.0. Yields abruptly increased in the pH interval 6.0 to 6.3. This was associated with elevated Ca concentrations in soil solutions.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0935-6304Keywords: High performance liquid chromatography, HPLC ; Reverse phase ; Internal standard ; Trimellitic anhydride ; Air sample ; Chemistry ; Analytical Chemistry and SpectroscopySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyAdditional Material: 2 Ill.Type of Medium: Electronic ResourceURL: