Search Results - (Author, Cooperation:R. Baer)
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1R. Shakya ; L. J. Reid ; C. R. Reczek ; F. Cole ; D. Egli ; C. S. Lin ; D. G. deRooij ; S. Hirsch ; K. Ravi ; J. B. Hicks ; M. Szabolcs ; M. Jasin ; R. Baer ; T. Ludwig
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-10-29Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; BRCA1 Protein/chemistry/*metabolism ; Basic-Leucine Zipper Transcription Factors/genetics/metabolism ; Cells, Cultured ; Disease Models, Animal ; Embryonic Stem Cells/metabolism ; *Genes, BRCA1 ; Ligands ; Mammary Neoplasms, Experimental/*genetics/metabolism ; Mice ; Mutant Proteins/chemistry/genetics/metabolism ; Pancreatic Neoplasms/*genetics/metabolism ; Phosphoproteins/*metabolism ; Protein Binding ; Protein Interaction Domains and Motifs ; Protein Multimerization ; RING Finger Domains ; Tumor Suppressor Proteins/chemistry/metabolism ; Ubiquitin-Protein Ligases/chemistry/metabolismPublished by: -
2L. Jiang ; N. Kon ; T. Li ; S. J. Wang ; T. Su ; H. Hibshoosh ; R. Baer ; W. Gu
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-03-25Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Transport System y+/biosynthesis/deficiency/genetics/metabolism ; Animals ; Biological Transport ; Cell Death ; Cystine/*metabolism ; Embryo, Mammalian/embryology/metabolism ; Embryonic Development ; Humans ; Iron/*metabolism ; Mice ; Neoplasms/*metabolism/*pathology ; Oxidative Stress ; Proto-Oncogene Proteins c-mdm2/deficiency/genetics ; Reactive Oxygen Species/*metabolism ; Substrate Specificity ; Tumor Suppressor Protein p53/antagonists & inhibitors/*metabolism ; Xenograft Model Antitumor AssaysPublished by: -
3BAER, R. J. ; FRANK, J. F. ; LOEWENSTEIN, M. ; BIRTH, G. S.
Oxford, UK : Blackwell Publishing Ltd
Published 1983Staff ViewISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: Compositional analysis data for 47 whey powders (including sweet whey, acid whey, demineralized delactosed whey and whey protein concentrates) were correlated with near infrared reflectance (NIR) measurements. The most useful wavelengths for determining constituent concentrations were chosen from 19 pre-selected wavelengths by using linear regression analysis. Results indicate that samples to be used for NIR calibrations should be similar in composition and should represent a limited range of constituent concentrations. Individual NIR calibrations need to be developed for each type of whey powder to be analyzed.Type of Medium: Electronic ResourceURL: -
4Rabbitts, T. H. ; Forster, A. ; Hamlyn, P. ; Baer, R.
[s.l.] : Nature Publishing Group
Published 1984Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Our previous studies of a translocated c-myc gene in the Raji Burkitt's lymphoma cell showed somatic mutations in exons 1 and 2. We have extended these observations to two other translocated c-myc genes and find a common occurrence of mutation in the noncoding exon 1. We also found that in ...Type of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] IT seems that the velocity of sound has never been measured in liquefied gases at low temperatures, probably because the customary methods were not easily practicable. It appeared reasonable to try as a new method the effect, which has recently been discovered by Debye-Sears and Lucas-Biquard, ...Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0005-7894Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0301-0104Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0891-4222Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Density matrix description of laser-induced hot electron mediated photodesorption of NO from Pt(111)Staff View
ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1572-9125Source: Springer Online Journal Archives 1860-2000Topics: MathematicsNotes: Abstract We here study some problems concerned with the computational analysis of finite partially ordered sets. We begin (in § 1) by showing that the matrix representation of a binary relationR may always be taken in triangular form ifR is a partial ordering. We consider (in § 2) the chain structure in partially ordered sets, answer the combinatorial question of how many maximal chains might exist in a partially ordered set withn elements, and we give an algorithm for enumerating all maximal chains. We give (in § 3) algorithms which decide whether a partially ordered set is a (lower or upper) semi-lattice, and whether a lattice has distributive, modular, and Boolean properties. Finally (in § 4) we give Algol realizations of the various algorithms.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1434-601XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Zusammenfassung Es wird gezeigt, daß der scheinbar mit einer Gleichstromspannung von weniger als 20 Volt in Helium brennende (abnorm niedervoltige) Lichtbogen dadurch zustande kommt, daß Schwingungen im Bogen vorhanden sind, die die Spannung an den Elektroden zeitweise bis auf über 20 Volt hinaufdrücken. Die in den Zeigerinstrumenten und Widerständen vorhandene Selbstinduktion der Apparatur ist zum Bestehen des Bogens notwendig, aber die Frequenz kann nicht aus der Thomsonschen Formel berechnet werden. Die Tonhöhe ist vielmehr noch von der Bogenstromstärke, der Heiztemperatur, dem Elektrodenabstand usw. abhängig.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1434-601XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1434-601XSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Zusammenfassung Auf den Ramanspektren vieler Flüssigkeiten ist noch ein kontinuierlicher Grund sichtbar. Es wird untersucht, ob dieses Kontinuum, das bei der Beobachtung senkrecht zum Einfallslicht meist vollständig depolarisiert ist, Ramanstrahlung darstellt. Hierzu wird geprüft, ob das Kontinuum bei Einstrahlung von zirkulär polarisiertem Licht und Beobachtung parallel zum Einfallslicht im umgekehrten Sinne zirkularpolarisiert ist wie der einfallende Lichtstrahl. Nur in diesem Falle kann nämlich nach der zuerst von Placzek aufgestellten Theorie das Kontinuum ein Ramaneffekt sein. Die Versuche werden an folgenden typischen, ausgewählten Beispielen von Flüssigkeiten, in denen ein starker kontinuierlicher Grund beobachtet wurde, ausgeführt: Benzol, Benzaldehyd, Glycerin, Schwefelsäure, Salpetersäure in verschiedenen Konzentrationen, Ameisensäure, Kalilauge, binäre Gemische von Methanol-Hexan und Methanol-Schwefelkohlenstoff im Temperaturgebiet der kritischen Opaleszenz. Das Kontinuum erweist sich in allen Fällen entweder als Fluoreszenzlicht oder als Rayleighstreuung des kontinuierlichen Grundes der Hg-Lampe in der Flüssigkeit, in keinem Falle aber als Ramanstrahlung. An einigen der untersuchten Flüssigkeiten (am eingehendsten an Benzaldehyd) wird gezeigt, daß der von der Theorie geforderte Zusammenhang zwischen der Depolarisation bei der Senkrechtbeobachtung und der Stärke der Umkehrung der Zirkularpolarisation bei der Farallelbeobachtung für das Ramanlinienspektrum so genau erfüllt ist, als die nur qualitativen Intensitätsschätzungen diese Prüfung gestatten.Type of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 1420-8938Source: Springer Online Journal Archives 1860-2000Topics: MathematicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-069XKeywords: Aged ; Contact sensitivity ; Langerhans cells ; Interleukin-2 ; Interferon-γSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Contact sensitivity responses were evaluated in young adult (3–5 months) and aged (16–26 months) BALB/c mice which were systemically treated with interleukin-2 (IL-2), interferon-γ (IFN-γ) or saline. Mice older than 16 months of age have deficient numbers of Ia+ Langerhans cells in addition to their well-known impaired T cell functions. They also have an impaired cell-mediated response to contact sensitization with 1-chloro-2,4,6-trinitrobenzene. This hyporesponsiveness in aged mice can be almost completely reversed by ness in aged mice can be almost completely reversed by IL-2 and is marginally improved by IFN-γ. Exposure of skin from aged mice to interleukin-2 or interferon-γ, both in vivo and invvitro, causes increases in the density of Ia+ Langerhans cells to levels approximating those in young mice. Since IFN-γ causes partial restitution while IL-2 fully restores the contact hypersensitivity in aged animals, we conclude that the hyporesponsiveness in aged mice results both from defective Ia antigen expression on the antigen-presenting Langerhans cells and from deficient T cell function.Type of Medium: Electronic ResourceURL: -
17Baer, R. ; Bankier, A. T. ; Biggin, M. D. ; Deininger, P. L. ; Farrell, P. J. ; Gibson, T. J. ; Hatfull, G. ; Hudson, G. S. ; Satchwell, S. C. ; Séguin, C. ; Tuffnell, P. S. ; Barrell, B. G.
[s.l.] : Nature Publishing Group
Published 1984Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the dideoxynucleotide/M13 sequencing procedure. Many RNA polymerase II promoters have been mapped and the mRNAs from these promoters have been assigned to the latent or ...Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The nucleotide sequence of a translocated c-myc gene in a Burkitt lymphoma reveals multiple base changes in the coding region. Twenty-five base changes, generating 16 codon alterations, were found in the first coding exon; no changes occur in the second coding exon. These changes are probably the ...Type of Medium: Electronic ResourceURL: -
19Rabbitts, T. H. ; Forster, A. ; Baer, R. ; Hamlyn, P. H.
[s.l.] : Nature Publishing Group
Published 1983Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] A transient expression assay was used to measure the ability of DNA segments to enhance transcription of immunoglobulin genes. This assay16 consists of transfecting cloned DNA into myeloma cells followed by S1-nuclease mapping analysis of transcribed RNA after a 2-day incubation of the cells. The ...Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] MAY I make the following remarks concerning Mr. A. C. Menzies' letter in NATURE of Oct. 5, p. 511, on the “Raman Effect from Powdered Crystals”. For several months I have been engaged in studying the Raman effect from different crystalline powders, and I can corroborate Mr. Menzies' statement ...Type of Medium: Electronic ResourceURL: