Search Results - (Author, Cooperation:R. B. Tesh)
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1L. C. Katzelnick ; J. M. Fonville ; G. D. Gromowski ; J. Bustos Arriaga ; A. Green ; S. L. James ; L. Lau ; M. Montoya ; C. Wang ; L. A. VanBlargan ; C. A. Russell ; H. M. Thu ; T. C. Pierson ; P. Buchy ; J. G. Aaskov ; J. L. Munoz-Jordan ; N. Vasilakis ; R. V. Gibbons ; R. B. Tesh ; A. D. Osterhaus ; R. A. Fouchier ; A. Durbin ; C. P. Simmons ; E. C. Holmes ; E. Harris ; S. S. Whitehead ; D. J. Smith
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-09-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Antigens, Viral/*immunology ; Cercopithecus aethiops ; Dengue Vaccines/immunology ; Dengue Virus/*classification/genetics/*immunology ; Evolution, Molecular ; Humans ; Immune Sera/immunology ; Phylogeny ; Serogroup ; Serotyping ; Vaccination ; Viral Envelope Proteins/geneticsPublished by: -
2Tan, Y., Lam, T. T.-Y., Heberlein-Larson, L. A., Smole, S. C., Auguste, A. J., Hennigan, S., Halpin, R. A., Fedorova, N., Puri, V., Stockwell, T. B., Shilts, M. H., Andreadis, T., Armstrong, P. M., Tesh, R. B., Weaver, S. C., Unnasch, T. R., Ciota, A. T., Kramer, L. D., Das, S. R.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-05-30Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
3Staff View
ISSN: 1432-8798Source: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary This paper reports the results of a series of laboratory experiments to determine the infectivity and pathogenesis of iridescent virus type 22 (IV 22) for six species of mosquitoes, phlebotomine sand flies and triatomid bugs. Following inoculation, IV 22 replicated in all of the species tested, without producing noticeable mortality within a 14 day observation period. Examination of the infected insects by immunofluorescence demonstrated large amounts of viral antigen in many different organs. Electron microscopy done on infected mosquitoes (Aedes aegypti) showed large numbers of virus particles within cells of the fat body, muscle tracheal and midgut epithelium. Virus replication in the mosquitoes was confined to host cell cytoplasm and was similar to that described in the natural blackfly (Simulium) host. Transovarial transmission of IV 22 could not be demonstraed inA. aegypti, and only a small percentage of mosquito larvae could be infected orally. Results of these experiments are compatible with observations of other iridescent viruses; IV 22 is highly infectious for a wide range of insects when introduced into their hemolymph, but it is not very infectious per os. These characteristics would appear to limit its value as a potential biocontrol agent for Diptera.Type of Medium: Electronic ResourceURL: