Search Results - (Author, Cooperation:P. Watson)
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1Latest Papers from Table of Contents or Articles in PressJennie Liao, Weiye Guan, Brian P. Boscoe, Joseph W. Tucker, John W. Tomlin, Michelle R. Garnsey, Mary P. Watson
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-05-11Publisher: American Chemical Society (ACS)Print ISSN: 1523-7060Electronic ISSN: 1523-7052Topics: Chemistry and PharmacologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressJ Scott Hosking, D Mac; Leod, T Phillips, C R Holmes, P Watson, E F Shuckburgh and D Mitchell
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-05-17Publisher: Institute of Physics (IOP)Print ISSN: 1748-9318Electronic ISSN: 1748-9326Topics: BiologyEnergy, Environment Protection, Nuclear Power EngineeringPublished by: -
3Latest Papers from Table of Contents or Articles in PressUller, T., Moczek, A. P., Watson, R. A., Brakefield, P. M., Laland, K. N.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-07-27Publisher: Genetics Society of America (GSA)Print ISSN: 0016-6731Topics: BiologyPublished by: -
4Latest Papers from Table of Contents or Articles in PressC. Curtis ; S. P. Shah ; S. F. Chin ; G. Turashvili ; O. M. Rueda ; M. J. Dunning ; D. Speed ; A. G. Lynch ; S. Samarajiwa ; Y. Yuan ; S. Graf ; G. Ha ; G. Haffari ; A. Bashashati ; R. Russell ; S. McKinney ; A. Langerod ; A. Green ; E. Provenzano ; G. Wishart ; S. Pinder ; P. Watson ; F. Markowetz ; L. Murphy ; I. Ellis ; A. Purushotham ; A. L. Borresen-Dale ; J. D. Brenton ; S. Tavare ; C. Caldas ; S. Aparicio
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-04-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Breast Neoplasms/classification/diagnosis/*genetics/*pathology ; DNA Copy Number Variations/*genetics ; Female ; *Gene Expression Profiling ; *Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks/genetics ; Genes, Neoplasm/genetics ; Genome, Human/*genetics ; Genomics ; Humans ; Kaplan-Meier Estimate ; MAP Kinase Kinase 4/genetics ; Polymorphism, Single Nucleotide/genetics ; Prognosis ; Protein Phosphatase 2/genetics ; Treatment OutcomePublished by: -
5Latest Papers from Table of Contents or Articles in PressS. P. Shah ; A. Roth ; R. Goya ; A. Oloumi ; G. Ha ; Y. Zhao ; G. Turashvili ; J. Ding ; K. Tse ; G. Haffari ; A. Bashashati ; L. M. Prentice ; J. Khattra ; A. Burleigh ; D. Yap ; V. Bernard ; A. McPherson ; K. Shumansky ; A. Crisan ; R. Giuliany ; A. Heravi-Moussavi ; J. Rosner ; D. Lai ; I. Birol ; R. Varhol ; A. Tam ; N. Dhalla ; T. Zeng ; K. Ma ; S. K. Chan ; M. Griffith ; A. Moradian ; S. W. Cheng ; G. B. Morin ; P. Watson ; K. Gelmon ; S. Chia ; S. F. Chin ; C. Curtis ; O. M. Rueda ; P. D. Pharoah ; S. Damaraju ; J. Mackey ; K. Hoon ; T. Harkins ; V. Tadigotla ; M. Sigaroudinia ; P. Gascard ; T. Tlsty ; J. F. Costello ; I. M. Meyer ; C. J. Eaves ; W. W. Wasserman ; S. Jones ; D. Huntsman ; M. Hirst ; C. Caldas ; M. A. Marra ; S. Aparicio
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-04-13Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Breast Neoplasms/diagnosis/*genetics/*pathology ; Clone Cells/metabolism/pathology ; DNA Copy Number Variations/genetics ; DNA Mutational Analysis ; Disease Progression ; *Evolution, Molecular ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/genetics ; Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; INDEL Mutation/genetics ; Mutation/*genetics ; Point Mutation/genetics ; Precision Medicine ; Reproducibility of Results ; Sequence Analysis, RNAPublished by: -
6Latest Papers from Table of Contents or Articles in PressGast, C. E., Silk, A. D., Zarour, L., Riegler, L., Burkhart, J. G., Gustafson, K. T., Parappilly, M. S., Roh-Johnson, M., Goodman, J. R., Olson, B., Schmidt, M., Swain, J. R., Davies, P. S., Shasthri, V., Iizuka, S., Flynn, P., Watson, S., Korkola, J., Courtneidge, S. A., Fischer, J. M., Jaboin, J., Billingsley, K. G., Lopez, C. D., Burchard, J., Gray, J., Coussens, L. M., Sheppard, B. C., Wong, M. H.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-09-13Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
7Latest Papers from Table of Contents or Articles in PressKim, K., Watson, P. A., Lebdai, S., Jebiwott, S., Somma, A. J., La Rosa, S., Mehta, D., Murray, K. S., Lilja, H., Ulmert, D., Monette, S., Scherz, A., Coleman, J. A.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-05-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
8Latest Papers from Table of Contents or Articles in PressSami, S. S., Haboubi, H. N., Ang, Y., Boger, P., Bhandari, P., de Caestecker, J., Griffiths, H., Haidry, R., Laasch, H.-U., Patel, P., Paterson, S., Ragunath, K., Watson, P., Siersema, P. D., Attwood, S. E.
BMJ Publishing Group
Published 2018Staff ViewPublication Date: 2018-05-09Publisher: BMJ Publishing GroupPrint ISSN: 0017-5749Electronic ISSN: 1468-3288Topics: MedicineKeywords: Open access, GutPublished by: -
9Latest Papers from Table of Contents or Articles in PressHitchcock, C., Gormley, S., OLeary, C., Rodrigues, E., Wright, I., Griffiths, K., Gillard, J., Watson, P., Hammond, E., Werner-Seidler, A., Dalgleish, T.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-01-31Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Clinical trials (epidemiology), Open access, Mental healthPublished by: -
10Latest Papers from Table of Contents or Articles in PressP. Dean; K. M. Sendra; T. A. Williams; A. K. Watson; P. Major; S. Nakjang; E. Kozhevnikova; A. V. Goldberg; E. R. S. Kunji; R. P. Hirt; T. M. Embley
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-04-28Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
11Articles: DFG German National LicensesStaff View
ISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: Analytic solutions for magnetic annihilation and reconnection in three-dimensional velocity fields are constructed. Exact and approximate solutions for three-dimensional fan current reconnection can be derived using prototype fields based on simple, one-component magnetic annihilation models. Certain reconnection solutions are found to be "fast," in the sense that the Ohmic dissipation rate scales independently of any positive power of the plasma resistivity η. Three-dimensional models can also possess novel features not contained in two-dimensional planar reconnection solutions. In particular, classes of solutions involving separated field nulls are found to possess multiple scalings for the Ohmic dissipation rate—a feature that has not been observed before. Several solutions are shown to have the potential to meet the extreme energy release characteristics of the solar flare. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1089-7674Source: AIP Digital ArchiveTopics: PhysicsNotes: The phenomena of steady-state magnetic annihilation and reconnection in the vicinity of magnetic nulls are considered. It is shown that reconnective solutions can be derived by superposing the velocity and magnetic fields of simple magnetic annihilation models. These solutions contain most of the previous models for magnetic merging and reconnection, as well as introducing several new solutions. The various magnetic dissipation mechanisms are classified by examining the scaling of the Ohmic diffusion rate with plasma resistivity. Reconnection solutions generally allow more favorable "fast" dissipation scalings than annihilation models. In particular, reconnection models involving the advection of planar field components have the potential to satisfy the severe energy release requirements of the solar flare. The present paper is mainly concerned with magnetic fields embedded in strictly planar flows—a discussion of the more complicated three-dimensional flow patterns is presented in Part II [Phys. Plasmas 4, 110 (1997)]. © 1997 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesWeiner, J. L. ; Valenzuela, C. F. ; Watson, P. L. ; Frazier, C. J. ; Dunwiddie, T. V.
Oxford, UK : Blackwell Science Ltd
Published 1997Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: The ability of ethanol to enhance GABAA receptor function remains controversial; conflicting observations have been made even in the same brain region, and when using apparently similar methodologies. In this study we characterized a single protocol variable, the initial incubation temperature of brain slices, that had dramatic effects on the ethanol sensitivity of GABAA inhibitory postsynaptic currents (IPSCs) recorded from rat hippocampal CA1 pyramidal neurons. Incubation of hippocampal slices at relatively low temperatures (11–15°C) immediately after slice preparation significantly affected a number of physiological and biochemical parameters. Such slices showed a decrease in extracellular inhibitory postsynaptic potential amplitude, a significant increase in the ethanol sensitivity of GABAA IPSCs in CA1 pyramidal neurons, no change in pentobarbital or flunitrazepam potentiation of IPSCs, and an increase in basal protein kinase C (PKC) activity relative to slices incubated at 31–33°C. In addition, the increase in ethanol sensitivity of GABAA IPSCs was blocked by chelerythrine, a selective inhibitor of PKC. These results suggest that differences in hippocampal slice incubation protocols may have contributed to the disparate results of previous investigations of ethanol modulation of GABAA receptor-mediated synaptic transmission in the rat hippocampus. In addition, these findings provide further evidence that PKC activity positively modulates the interaction between ethanol and GABAA receptors in the mammalian brain.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesBradley-Watson, P. J. ; Beard, R. J. ; Craft, L.
Oxford, UK : Blackwell Publishing Ltd
Published 1973Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Severe damage to the cervix after the intra-amniotic injection of urea and prostaglandin F2α is reported. Speculum examination is advised following completion of mid-trimester abortion induced by oxytocic agents.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A case history is presented which led to recognition of the fact that a fetal meningocoele can be diagnosed antenatally because it can produce a characteristic pattern on an ultrasonic B scan.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesBallard, R. M. ; Bradley-Watson, P. J. ; Johnstone, F. D. ; Kenney, A. ; McCarthy, T. G. ; Campbell, Stuart ; Weston, Jeanne
Oxford, UK : Blackwell Publishing Ltd
Published 1973Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The prophylactic effect of low doses of subcutaneous heparin in the prevention of deep vein thrombosis after major gynaecological surgery was investigated in a clinical trial involving 110 patients. Evidence of thrombosis was detected by the 1251-labelled fibrinogen test in 16 out of 55 patients (29 per cent) in the control group, and in 2 out of 55 patients (3.6 per cent) in the heparin-treated group. Only longevity had a significant association with the development of deep vein thrombosis.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesIMESON, A. P. ; WATSON, P. R. ; MITCHELL, J. R. ; LEDWARD, D. A.
Oxford, UK : Blackwell Publishing Ltd
Published 1978Staff ViewISSN: 1365-2621Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Process Engineering, Biotechnology, Nutrition TechnologyNotes: Bovine serum albumin (BSA) and blood plasma formed insoluble complexes with alginate, pectate and carboxymethyl cellulose (CMC) under appropriate conditions of pH. More than 90% of the BSA could be recovered by all three polysaccharides at ionic strengths of 〈 0.001 and at the optimum pH for recovery and a ratio of protein to polysaccharide of about 5:1. At low ratios of protein to polysaccharide, alginate and CMC appeared to resolubilize the complex. When the ionic strength was increased to 0.2 almost complete recovery could still be obtained with alginate and pectate at protein: polysaccharide ratios of 5:1 and 3:1 respectively but the efficiency of precipitation was reduced and the range of the ratios for optimum recovery narrowed. The results for precipitation from blood plasma were very similar to those obtained in the BSA studies. A crude pectate preparation obtained from orange peel gave results similar to pure pectate except that three times as much was required to precipitate a given amount of protein.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1365-2044Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: We have developed a simple instrument for pressure algometry. It can be made easily using components found in most anaesthetic rooms. Ten students were able to make the device using written instructions. All the resulting algometers performed within 10% accuracy limits for values up to 4 kgcm−2.Type of Medium: Electronic ResourceURL: