Search Results - (Author, Cooperation:P. Walter)
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1Timothy P. Moneypenny , II, Anna Yang, Nathan P. Walter, Toby J. Woods, Danielle L. Gray, Yang Zhang, Jeffrey S. Moore
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-04-25Publisher: American Chemical Society (ACS)Print ISSN: 0002-7863Electronic ISSN: 1520-5126Topics: Chemistry and PharmacologyPublished by: -
2P. Sarrazin, D. Blake, M. Gailhanou, F. Marchis, C. Chalumeau, S. Webb, P. Walter, E. Schyns, K. Thompson and T. Bristow
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-04-18Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
3M. Lu ; D. A. Lawrence ; S. Marsters ; D. Acosta-Alvear ; P. Kimmig ; A. S. Mendez ; A. W. Paton ; J. C. Paton ; P. Walter ; A. Ashkenazi
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Apoptosis ; Caspases ; Endoplasmic Reticulum Stress/genetics/*physiology ; Endoribonucleases/metabolism ; HCT116 Cells ; Humans ; Ligands ; Mice ; Mice, Inbred C57BL ; Protein-Serine-Threonine Kinases/metabolism ; RNA Stability ; RNA, Messenger/metabolism ; Receptors, TNF-Related Apoptosis-Inducing Ligand/agonists/genetics/*physiology ; Transcription Factor CHOP ; *Unfolded Protein ResponsePublished by: -
4S. R. Starck ; J. C. Tsai ; K. Chen ; M. Shodiya ; L. Wang ; K. Yahiro ; M. Martins-Green ; N. Shastri ; P. Walter
American Association for the Advancement of Science (AAAS)
Published 2016Staff ViewPublication Date: 2016-01-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: 5' Untranslated Regions/*genetics ; Cell Tracking ; Codon, Initiator/genetics ; Eukaryotic Initiation Factor-2/metabolism ; Heat-Shock Proteins/*biosynthesis/genetics ; Humans ; Open Reading Frames/genetics ; Protein Biosynthesis/*genetics ; RNA, Messenger/*genetics ; Stress, Physiological/*genetics ; T-Lymphocytes/metabolism/microbiology/physiologyPublished by: -
5Staff View
Publication Date: 2011-08-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites ; Cathepsin A/chemistry/metabolism ; Endoplasmic Reticulum/*metabolism ; Fluorescence Polarization ; Fungal Proteins/chemistry/metabolism ; Glutathione Transferase/metabolism ; HSP70 Heat-Shock Proteins/chemistry/metabolism ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Membrane Glycoproteins/*chemistry/*metabolism ; Mutant Proteins/chemistry/metabolism ; Protein Binding ; Protein Conformation ; Protein Folding ; Protein Interaction Domains and Motifs ; Protein Multimerization ; Protein-Serine-Threonine Kinases/*chemistry/*metabolism ; Saccharomyces cerevisiae Proteins/chemistry/genetics/*metabolism ; Stress, Physiological ; *Unfolded Protein ResponsePublished by: -
6Staff View
Publication Date: 2011-11-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Activating Transcription Factor 6/metabolism ; Animals ; Apoptosis ; Endoplasmic Reticulum/*metabolism ; *Endoplasmic Reticulum Stress ; Endoplasmic Reticulum-Associated Degradation ; Endoribonucleases/metabolism ; Gene Expression Regulation ; Homeostasis ; Humans ; Protein-Serine-Threonine Kinases/metabolism ; Proteolysis ; Signal Transduction ; *Unfolded Protein Response ; Yeasts/genetics/metabolism ; eIF-2 Kinase/metabolismPublished by: -
7Staff View
Type of Medium: articlePublication Date: 1995Keywords: Fachdidaktik ; Gentechnologie ; Lebensmittel ; Mikrobiologie ; ErwachsenenbildungIn: Die Ernährung, Bd. 19 (1995) H. 9, 3 S., 0250-1554Language: German -
8Staff View
Type of Medium: articlePublication Date: 1995Keywords: Biotechnologie ; Gentechnologie ; Nachweis ; Lebensmitteltechnologie ; Lebensmittelrecht ; VerbraucherschutzIn: Biologie in unserer Zeit, Bd. 25 (1995) H. 4 (Spezial), S. 246-255, 0045-205XLanguage: GermanNote: Literaturangaben -
9Staff View
Publication Date: 2018-04-27Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
10Tsai, J. C., Miller-Vedam, L. E., Anand, A. A., Jaishankar, P., Nguyen, H. C., Renslo, A. R., Frost, A., Walter, P.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-03-30Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Biochemistry, Online OnlyPublished by: -
11Staff View
Publication Date: 2018-07-14Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
12Natalie A. Gude, Fareheh Firouzi, Kathleen M. Broughton, Kelli Ilves, Kristine P. Nguyen, Christina R. Payne, Veronica Sacchi, Megan M. Monsanto, Alexandria R. Casillas, Farid G. Khalafalla, Bingyan J. Wang, David E. Ebeid, Roberto Alvarez, Walter P. Dembitsky, Barbara A. Bailey, Jop van Berlo, Mark A. Sussman
American Heart Association (AHA)
Published 2018Staff ViewPublication Date: 2018-06-22Publisher: American Heart Association (AHA)Print ISSN: 0009-7330Electronic ISSN: 1524-4571Topics: MedicineKeywords: Basic Science Research, Cell Signaling/Signal Transduction, Myocardial Biology, Stem Cells, Genetically Altered and Transgenic ModelsPublished by: -
13LeGrange, Jane D. ; Riegler, Hans E. ; Zurawsky, Walter P. ; Scarlata, Suzanne F.
College Park, Md. : American Institute of Physics (AIP)
Published 1989Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The orientational order parameters 〈P2〉 and 〈P4〉, of cadmium stearate Langmuir–Blodgett multilayers have been calculated from steady state fluorescence anisotropy experiments. It has been shown that it is valid to model the polarization components using the assumptions that the fluorescent probes are axially symmetric, the film is azimuthally symmetric within the plane, and that the rotational motion is slow enough to be neglected. Although the data do not preclude a dependence of anisotropy on thickness, within the sample-to-sample variations, there is no significant effect of thickness on orientational order. The order parameters for newly deposited films are 〈P2〉=0.33 and 〈P4〉=0.02. The orientational order decreases in the first 600 h after deposition, and then remains stable for at least several months.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 1530-9134Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: EconomicsType of Medium: Electronic ResourceURL: -
15JASKI, BRIAN E. ; BRANCH, KELLEY R. ; DASSE, KURT A. ; DEMBITSKY, WALTER P.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1540-8183Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Currently used left ventricular assist devices allow chronic mechanical cardiac support in the patient with end-stage heart failure. Recognition and treatment of problems uniquely associated with this device may be increasingly important for the invasive cardiologist as application of this technology becomes more prevalent. (J Interven Cardiol 1995;8:275-282)Type of Medium: Electronic ResourceURL: -
16DAILY, PAT O. ; DEMBITSKY, WALTER P. ; IVERSEN, STEIN
Oxford, UK : Blackwell Publishing Ltd
Published 1989Staff ViewISSN: 1540-8191Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Pulmonary embolism infrequently results in severe chronic pulmonary arterial obstruction. However, when it does, affected patients are significantly symptomatic and have shortened survival. Medical management has proven ineffective. In the majority of surgical reports, unilateral thoracotomy with distal pulmonary arteriotomies has been emphasized. The average operative mortality was 22%. In this article, we discuss various preoperative considerations and describe in detail a surgical approach using median sternotomy for bilateral pulmonary thrombo-endarterectomy with cardiopulmonary bypass, deep hypothermia and circulatory arrest. With this standardized approach in 103 consecutive patients from October 1, 1984, to September 20, 1988, the hospital mortality (death within 30 days or during hospitalization) has been 11.7%.Type of Medium: Electronic ResourceURL: -
17Reynolds, C. Hugh ; Betts, Joanna C. ; Blackstock, Walter P. ; Nebreda, Angel R. ; Anderton, Brian H.
Oxford UK : Blackwell Science Ltd.
Published 2000Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: The stress-activated kinases c-Jun N-terminal kinase (JNK)and p38 are members of the mitogen-activated protein (MAP) kinase family andtake part in signalling cascades initiated by various forms of stress. Theirtargets include the microtubule-associated protein tau, which becomeshyperphosphorylated in Alzheimer's disease. It is necessary, as a forerunnerfor in vivo studies, to identify the protein kinases and phosphatases that areresponsible for phosphate turnover at individual sites. Using nanoelectrospraymass spectrometry, we have undertaken an extensive comparison ofphosphorylation in vitro by several candidate tau kinases, namely, JNK, p38,ERK2, and glycogen synthase kinase 3β (GSK3β). Between 10 and 15sites were identified for each kinase. The three MAP kinases phosphorylatedSer202 and Thr205 but not detectably Ser199,whereas conversely GSK3β phosphorylated Ser199 but notdetectably Ser202 or Thr205. PhosphorylatedSer404 was found with all of these kinases except JNK. The MAPkinases may not be strictly proline specific: p38 phosphorylated thenonproline sites Ser185, Thr245, Ser305, andSer356, whereas ERK2 was the most strict. All of the sites detectedexcept Thr245 and Ser305 are known or suspected phosphorylation sites in paired helical filament-tau extracted from Alzheimer brains. Thus, the three MAP kinases and GSK3β are importantly all strong candidates as tau kinases that may be involved in the pathogenic hyperphosphorylation of tau in Alzheimer's disease.Type of Medium: Electronic ResourceURL: -
18Hanger, Diane P. ; Betts, Joanna C. ; Loviny, Thérèse L. F. ; Blackstock, Walter P. ; Anderton, Brian H.
Oxford, UK : Blackwell Science Ltd
Published 1998Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Paired helical filaments (PHFs) are the structural constituents of neurofibrillary tangles in Alzheimer's disease and are composed of hyperphosphorylated forms of the microtubule-associated protein tau (PHF-tau). Pathological hyperphosphorylation of tau is believed to be an important contributor to the destabilisation of microtubules and their subsequent disappearance from tangle-bearing neurons in Alzheimer's disease, making elucidation of the mechanisms that regulate tau phosphorylation an important research goal. Thus, it is essential to identify, preferably by direct sequencing, all of the sites in PHF-tau that are phosphorylated, a task that is incomplete because of the difficulty to date of purifying insoluble PHF-tau to homogeneity and in sufficient quantities for structural analysis. Here we describe the solubilisation of PHF-tau followed by its purification by Mono Q chromatography and reversed-phase HPLC. Phosphopeptides from proteolytically digested PHF-tau were sequenced by nanoelectrospray mass spectrometry. We identified 22 phosphorylation sites in PHF-tau, including five sites not previously identified. The combination of our new data with previous reports shows that PHF-tau can be phosphorylated on at least 25 different sites.Type of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1468-2494Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Subjects with medium to dark skin and many exhibiting facial age spots or discolorations participated in this twelve week study to evaluate the skin whitening ability of lactic and ascorbic acid. Using clinical and biophysical test methods we observed prolonged treatment with 8.8% L(+) lactic acid resulted in no significant effects on skin pigmentation. However treatment with L(+) lactic acid supplemented with ascorbic acid (1%) did produce a whitening effect which becomes apparent after three months. These effects were demonstrated clinically by the test panelists, and trained clinicians, and with objective instrumental methods. We observed a general skin lightening and did see a modest preferential lightening of age spots with the combination of acids.Type of Medium: Electronic ResourceURL: -
20Skoczylas, Walter P. ; Rempfer, Gertrude F. ; Griffith, O. Hayes
[S.l.] : American Institute of Physics (AIP)
Published 1994Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: A review of electron optical bench literature is presented, and the designs of two optical benches used by the authors are described. One bench was designed for testing individual electrostatic electron lenses and in-line optical systems, for example, emission electron microscopes and transmission electron microscopes. It has been in operation for many years. The second electron optical bench is new. It is a branched system designed for several purposes: to study correction of spherical and chromatic aberration with an electron mirror, and to gain experience with low energy electron microscopy (LEEM) optics. The alignment of the electron optical support structure is independent of the vacuum housing, and the bench is designed to be operated either horizontally or vertically. As a demonstration of the performance of the new bench in the horizontal mode, a test pattern on a silicon surface was imaged with LEEM optics.Type of Medium: Electronic ResourceURL: