Search Results - (Author, Cooperation:P. Schofield)
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1Bilton, T. P., Schofield, M. R., Black, M. A., Chagne, D., Wilcox, P. L., Dodds, K. G.
Genetics Society of America (GSA)
Published 2018Staff ViewPublication Date: 2018-05-02Publisher: Genetics Society of America (GSA)Print ISSN: 0016-6731Topics: BiologyPublished by: -
2T. Gkikopoulos ; P. Schofield ; V. Singh ; M. Pinskaya ; J. Mellor ; M. Smolle ; J. L. Workman ; G. J. Barton ; T. Owen-Hughes
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-09-24Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine Triphosphatases/genetics/*metabolism ; Adenosine Triphosphate/metabolism ; Chromatin Assembly and Disassembly ; DNA, Fungal/genetics ; DNA-Binding Proteins/genetics/*metabolism ; Gene Expression Regulation, Fungal ; Genes, Fungal ; *Genome, Fungal ; Mutation ; Nucleosomes/*genetics/physiology/ultrastructure ; Saccharomyces cerevisiae/*genetics/physiology ; Saccharomyces cerevisiae Proteins/genetics/*metabolism ; Transcription Initiation SitePublished by: -
3Burnett, D. L., Langley, D. B., Schofield, P., Hermes, J. R., Chan, T. D., Jackson, J., Bourne, K., Reed, J. H., Patterson, K., Porebski, B. T., Brink, R., Christ, D., Goodnow, C. C.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-13Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, ImmunologyPublished by: -
4Staff View
Publication Date: 2018-06-22Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, Medicine, Diseases, Online OnlyPublished by: -
5Toumbourou, J. W. ; Williams, I. R. ; White, V. M. ; Snow, P. C. ; Munro, G. D. ; Schofield, P. E.
Oxford, UK : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1360-0443Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicinePsychologyNotes: Aims To establish predictors of age 21 alcohol-related harm from prior drinking patterns, current levels of alcohol consumption and use of controlled drinking strategies.Participants One thousand, five hundred and ninety-six students recruited from an initial sample of 3300 during their final year of high school in 1993.Design Longitudinal follow-up across five waves of data collection.Setting Post high school in Victoria, Australia.Measurements Self-administered surveys examining a range of health behaviours, including alcohol consumption patterns and related behaviour.Findings Drinking behaviours at age 21 were found to be strongly predicted by drinking trajectories established through the transition from high school. Multivariate regression analysis revealed that alcohol-related harms at age 21 were reduced where current levels of alcohol use fell within limits recommended in Australian national guidelines. After controlling for this effect it was found that the range of strategies employed by participants to control alcohol use maintained a small protective influence. Post-high-school drinking trajectories continued to demonstrate a significant effect after controlling for current behaviours. Findings revealed that over one quarter of males and females drank alcohol, but on a less-than-weekly basis. This pattern of alcohol use demonstrated considerable stability through the post-school transition and was associated with a low level of subsequent harm at age 21.Conclusions Future research should investigate whether encouraging more Australian adolescents to drink alcohol on a less-than-weekly basis may be a practical intervention target for reducing alcohol-related harms.Type of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1095-8649Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: The code Gobiosoma robustum and clown Microgobius gulosus gobies were grown in the laboratory over 27 days at two salinities (5 and 35), two food levels [low (a fixed proportion of initial mass) and high (saturation)] and both with and without the presence of the other species. Both species exhibited greatest growth at the high food level and the low (5) salinity. Neither species was affected by the presence of the other species, and there were no overall differences in growth between the two species. Thus, the observed competitive superiority of G. robustum over M. gulosus does not seem to confer an advantage relative to feeding success. Furthermore, as growth of G. robustum was greater at the lower salinity, it is clear that some factor other than salinity is restricting this species from north-eastern Florida Bay. Additional work on the importance of predation and food resources in various regions of Florida Bay is needed to further evaluate the underlying mechanisms responsible for the bay-wide distribution of these species.Type of Medium: Electronic ResourceURL: -
7Eisenberg, M. ; Stevens, L. H. ; Schofield, P. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1978Staff ViewISSN: 1440-0960Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Drug therapy of epidermolysis bullosa dystrophica (E.B.D.) for the past forty years is reviewed.A reproducible method for the direct extraction of collagenase and collagen peptidase from skin homogenates is described.Markedly elevated collagenase and collagen peptidase activity is demonstrated in skin of dystrophic E.B. patients. Diphenylhydantoin in pharmacological doses is shown to cause significant inhibition of the collagenolytic system both in vitro and in vivo. Diphenylhydantoin was used parenterally in two children with proven E.B.D. and was found to have a beneficial effect on skin fragility.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A series of 20 cases of radiation bowel disease (RBD) was studied qualitatively and the arterial changes were studied quantitatively. A control series of 45 cases was studied. In the control cases there were positive correlations between the medial thickness of all vessels studied and the diastolic blood pressure as well as the incidence of intimal fibrosis in both intramural and extramural arteries. The medial thickness in all the arteries in cases of RBD was significantly higher than in the controls. This was probably due to the large number of fibrin thrombi which increased the vascular resistance. The degree of intimal fibrosis of the intramural arteries and arterioles was significantly greater than in the controls. Similarly the incidence of intimal fibrosis in all arterioles and intramural arteries was greater than the control group. The degree of intimal fibrosis was related to the dose of radiation received. The effect of radiation was an on-going process since the percentage of arterioles with intimal fibrosis increased with the time after radiotherapy. Blood pressure and age played no part in these correlations in RBD. The most consistently observed qualitative changes in RBD were in the arteries, arterioles and to a lesser extent the veins. These showed fibrin thrombi, fibrinoid necrosis, subendothelial oedema and fibrin. Various stages of healing were seen in the vessels. We believe that the blood vessels are the main site of injury in RBD and that the endothelial cell is the initial target for radiation damage.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Insects also seem to be unique in their ability to regulate the ionic composition of the nerve cell environment. It has frequently been postulated that this ionic homeostasis results from active transport by the perineurium and underlying glial elements (Fig. 1). In particular, it has been ...Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The hydroxylation reaction is believed to proceed through two intermediate steps: (1) the metal -catalysed oxidation of ascorbic acid to hydrogen and monodehydroascorbic acid free radicals9; (2) interaction of these free radicals with the substrate10. Under the experimental conditions usually ...Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] IN 1954, Udenfriend et aL1 showed that hydroxylation of aromatic compounds could be effected by a phosphate-buffered aqueous system containing oxygen, a metal complex and ascorbic acid. The significance of this system lies in the fact that the products of such aromatic hydroxylations are similar to ...Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0140-1971Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: -
13Le, F. ; Mitchell, P. ; Vivero, C. ; Waters, B. ; Donald, J. ; Selbie, L.A. ; Shine, J. ; Schofield, P.
Amsterdam : ElsevierStaff ViewISSN: 0165-0327Keywords: Bipolar disorder ; Chromosome 20 ; G protein ; G"s-α ; Linkage analysisSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0005-2787Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0005-2787Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 0014-5793Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Andrew, M. ; Burholt, I.M.V. ; Kernoghan, N.J. ; Lynch, T.P. ; Mackison, R. ; Mealor, D. ; Price, J.A. ; Schofield, P.
Amsterdam : ElsevierStaff ViewISSN: 0021-9673Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0006-291XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0010-4655Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Computer SciencePhysicsType of Medium: Electronic ResourceURL: