Search Results - (Author, Cooperation:P. Nolan)
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1Benedict Anchang, Kara L. Davis, Harris G. Fienberg, Brian D. Williamson, Sean C. Bendall, Loukia G. Karacosta, Robert Tibshirani, Garry P. Nolan, Sylvia K. Plevritis
National Academy of Sciences
Published 2018Staff ViewPublication Date: 2018-05-02Publisher: National Academy of SciencesPrint ISSN: 0027-8424Electronic ISSN: 1091-6490Topics: BiologyMedicineNatural Sciences in GeneralPublished by: -
2Safoura S. Mirkhalaf, Samuel P. Nolan, and Simon A. Haine
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-05-26Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Matter waves and collective properties of cold atoms and moleculesPublished by: -
3Monica E. Kleinman, Gavin D. Perkins, Farhan Bhanji, John E. Billi, Janet E. Bray, Clifton W. Callaway, Allan de Caen, Judith C. Finn, Mary Fran Hazinski, Swee Han Lim, Ian Maconochie, Vinay Nadkarni, Robert W. Neumar, Nikolaos Nikolaou, Jerry P. Nolan, Amelia Reis, Alfredo F. Sierra, Eunice M. Singletary, Jasmeet Soar, David Stanton, Andrew Travers, Michelle Welsford, David Zideman
American Heart Association (AHA)
Published 2018Staff ViewPublication Date: 2018-05-30Publisher: American Heart Association (AHA)Electronic ISSN: 1524-4539Topics: MedicineKeywords: Statements and GuidelinesPublished by: -
4Staff View
Publication Date: 2018-12-05Publisher: American Physical Society (APS)Print ISSN: 1050-2947Electronic ISSN: 1094-1622Topics: PhysicsKeywords: Matter waves and collective properties of cold atoms and moleculesPublished by: -
5P. Uzureau ; S. Uzureau ; L. Lecordier ; F. Fontaine ; P. Tebabi ; F. Homble ; A. Grelard ; V. Zhendre ; D. P. Nolan ; L. Lins ; J. M. Crowet ; A. Pays ; C. Felu ; P. Poelvoorde ; B. Vanhollebeke ; S. K. Moestrup ; J. Lyngso ; J. S. Pedersen ; J. C. Mottram ; E. J. Dufourc ; D. Perez-Morga ; E. Pays
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-08-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Africa ; Animals ; Animals, Genetically Modified ; Apolipoproteins/antagonists & inhibitors/*blood/*metabolism/toxicity ; Cell Membrane/chemistry/metabolism ; Cysteine Proteases/metabolism ; Haptoglobins/metabolism ; Hemoglobins/metabolism ; Hemolysis ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lipid Metabolism ; Lipoproteins, HDL/antagonists & inhibitors/*blood/chemistry/*metabolism/toxicity ; Parasites/pathogenicity/physiology ; Protein Structure, Secondary ; Serum/chemistry/parasitology ; Trypanosoma brucei gambiense/drug effects/pathogenicity/*physiology ; Trypanosomiasis, African/parasitology ; Variant Surface Glycoproteins, Trypanosoma/chemistry/metabolismPublished by: -
6M. Ahmadi ; M. Baquero-Ruiz ; W. Bertsche ; E. Butler ; A. Capra ; C. Carruth ; C. L. Cesar ; M. Charlton ; A. E. Charman ; S. Eriksson ; L. T. Evans ; N. Evetts ; J. Fajans ; T. Friesen ; M. C. Fujiwara ; D. R. Gill ; A. Gutierrez ; J. S. Hangst ; W. N. Hardy ; M. E. Hayden ; C. A. Isaac ; A. Ishida ; S. A. Jones ; S. Jonsell ; L. Kurchaninov ; N. Madsen ; D. Maxwell ; J. T. McKenna ; S. Menary ; J. M. Michan ; T. Momose ; J. J. Munich ; P. Nolan ; K. Olchanski ; A. Olin ; A. Povilus ; P. Pusa ; C. O. Rasmussen ; F. Robicheaux ; R. L. Sacramento ; M. Sameed ; E. Sarid ; D. M. Silveira ; C. So ; T. D. Tharp ; R. I. Thompson ; D. P. van der Werf ; J. S. Wurtele ; A. I. Zhmoginov
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-01-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
7S. C. Bendall ; E. F. Simonds ; P. Qiu ; A. D. Amir el ; P. O. Krutzik ; R. Finck ; R. V. Bruggner ; R. Melamed ; A. Trejo ; O. I. Ornatsky ; R. S. Balderas ; S. K. Plevritis ; K. Sachs ; D. Pe'er ; S. D. Tanner ; G. P. Nolan
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-05-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Algorithms ; Antibodies ; Antigens, Surface/analysis ; B-Lymphocytes/drug effects/immunology/metabolism ; Bone Marrow Cells/cytology/*drug effects/*immunology/metabolism ; Cytokines/metabolism ; Dasatinib ; Flow Cytometry/*methods ; Hematopoiesis ; Humans ; Immunophenotyping ; Lanthanoid Series Elements ; Leukocytes, Mononuclear/drug effects/immunology/metabolism ; Lymphocyte Activation ; Lymphocyte Subsets/*drug effects/*immunology/metabolism ; Mass Spectrometry ; Phosphorylation ; Protein Kinase Inhibitors/pharmacology ; Protein-Tyrosine Kinases/antagonists & inhibitors ; Pyrimidines/*pharmacology ; *Signal Transduction/drug effects ; Single-Cell Analysis/*methods ; T-Lymphocytes/drug effects/immunology/metabolism ; Thiazoles/*pharmacology ; Transition ElementsPublished by: -
8Jared M. Churko; Priyanka Garg; Barbara Treutlein; Meenakshi Venkatasubramanian; Haodi Wu; Jaecheol Lee; Quinton N. Wessells; Shih-Yu Chen; Wen-Yi Chen; Kashish Chetal; Gary Mantalas; Norma Neff; Eric Jabart; Arun Sharma; Garry P. Nolan; Nathan Salomonis; Joseph C. Wu
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-11-22Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2041-1723Topics: BiologyChemistry and PharmacologyNatural Sciences in GeneralPhysicsPublished by: -
9M. H. Spitzer ; P. F. Gherardini ; G. K. Fragiadakis ; N. Bhattacharya ; R. T. Yuan ; A. N. Hotson ; R. Finck ; Y. Carmi ; E. R. Zunder ; W. J. Fantl ; S. C. Bendall ; E. G. Engleman ; G. P. Nolan
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-07-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bone Marrow/immunology ; Circadian Rhythm/immunology ; Flow Cytometry ; Genetic Variation ; Humans ; Immune System/*cytology/*immunology ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Phenotype ; Reference StandardsPublished by: -
10S. Krishnaswamy ; M. H. Spitzer ; M. Mingueneau ; S. C. Bendall ; O. Litvin ; E. Stone ; D. Pe'er ; G. P. Nolan
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-10-25Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; CD4-Positive T-Lymphocytes/*immunology ; Computer Simulation ; Image Cytometry ; Male ; Mice ; Mice, Mutant Strains ; Mitogen-Activated Protein Kinase 1/genetics ; Receptors, Antigen, T-Cell/*metabolism ; Ribosomal Protein S6/metabolism ; Signal Transduction ; Single-Cell Analysis/*methods ; Systems Biology/*methods ; eIF-2 Kinase/metabolismPublished by: -
11Staff View
Publication Date: 2018-09-22Publisher: American Chemical Society (ACS)Print ISSN: 0001-4842Electronic ISSN: 1520-4898Topics: Chemistry and PharmacologyPublished by: -
12C. Amole ; M. D. Ashkezari ; M. Baquero-Ruiz ; W. Bertsche ; P. D. Bowe ; E. Butler ; A. Capra ; C. L. Cesar ; M. Charlton ; A. Deller ; P. H. Donnan ; S. Eriksson ; J. Fajans ; T. Friesen ; M. C. Fujiwara ; D. R. Gill ; A. Gutierrez ; J. S. Hangst ; W. N. Hardy ; M. E. Hayden ; A. J. Humphries ; C. A. Isaac ; S. Jonsell ; L. Kurchaninov ; A. Little ; N. Madsen ; J. T. McKenna ; S. Menary ; S. C. Napoli ; P. Nolan ; K. Olchanski ; A. Olin ; P. Pusa ; C. O. Rasmussen ; F. Robicheaux ; E. Sarid ; C. R. Shields ; D. M. Silveira ; S. Stracka ; C. So ; R. I. Thompson ; D. P. van der Werf ; J. S. Wurtele
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-03-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
13E. Lujan ; E. R. Zunder ; Y. H. Ng ; I. N. Goronzy ; G. P. Nolan ; M. Wernig
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-02Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 5'-Nucleotidase/metabolism ; Animals ; Antigens, CD/metabolism ; Antigens, CD15/metabolism ; Antigens, Neoplasm/metabolism ; Biomarkers/analysis/metabolism ; Cell Adhesion Molecules/metabolism ; *Cell Separation ; Cellular Reprogramming/*physiology ; DAX-1 Orphan Nuclear Receptor/metabolism ; DNA-Binding Proteins/metabolism ; Epithelial Cells/metabolism ; Fibroblasts/cytology/metabolism ; *Flow Cytometry ; Gene Expression Profiling ; Homeodomain Proteins/metabolism ; Induced Pluripotent Stem Cells/*cytology/*metabolism ; Integrin alpha4/metabolism ; Mice ; Nuclear Proteins/metabolism ; SOXB1 Transcription Factors/metabolism ; Time Factors ; Transcription Factors/analysis/*metabolismPublished by: -
14Doyle, E. ; Nolan, P. M. ; Bell, R. ; Regan, C. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract: Intraventricular infusions of anti-neural cell adhesion molecule (anti-NCAM) are demonstrated to inhibit consolidation of a passive avoidance response when administered in the 6-8-h posttraining period. Anti-NCAM was ineffective when administered during training or at any other time up to 10 h thereafter, and no amnesic effects were observed with absorbed anti-NCAM or anti-neurofilament protein. Amnesia was observed only at the 48-h recall time, and this could not be attributed to poor antibody penetration or a prolonged residence time, as studies with 125I-labelled anti-NCAM in trained animals demonstrated a rapid accumulation into all brain regions, and this was marked in the olfactory bulb and hippocampus, areas showing an inherent and paradigm-specific increase in NCAM sialylation state, respectively. The lack of an amnesic action at the 24-h recall time is attributed to anti-NCAM-impaired synapse structuring becoming apparent following the paradigm-specific increases in NCAM sialylation state.Type of Medium: Electronic ResourceURL: -
15Davis, J. E. ; Karseboom, S. G. ; Nolan, P. D. ; Mullins, C. B.
College Park, Md. : American Institute of Physics (AIP)
Published 1996Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The interaction of nitric oxide (NO) with an Ir(111) surface has been studied with supersonic molecular beam techniques and electron energy loss spectroscopy. Initial adsorption probability S0, measurements as a function of incident kinetic energy Ei, surface temperature Ts, and angle of incidence θi reveal that separate mechanisms govern adsorption at low and high kinetic energy. This distinction is reflected in measurements of the initial molecular adsorption probability where a decrease in the value of S0 with increasing Ts (between 77 and 300 K) is observed at low kinetic energy (Ei〈0.45 eV), but no surface temperature dependence is detected at high kinetic energy in this temperature range. We present a model describing both the molecular and dissociative chemisorption of NO on Ir(111). At low kinetic energy, NO adsorbs initially as a physically adsorbed species. From this state, desorption to the gas phase or conversion to a molecularly chemisorbed state on the surface are competing processes which depend on surface temperature. The molecularly chemisorbed state is the precursor to dissociation for elevated surface temperatures. At high kinetic energy, NO adsorption occurs directly into the molecularly chemisorbed well, with the probability of trapping as a physically adsorbed species near zero and with undetectable direct dissociation. Indeed, after exposure of the Ir(111) surface at 77 K to a high kinetic energy (1.3 eV) beam, surface vibrational spectroscopy measurements show only features attributable to molecularly chemisorbed NO. The success of this model in describing our measurements is demonstrated by the separate calculation from low and high kinetic energy data of rate constants corresponding to forward and reverse conversion from the molecularly chemisorbed well. Additionally, we discuss attempts to promote dissociation on the surface with vibrational energy and with a combination of translational and surface thermal energy. © 1996 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. The interaction of the serotonin precursor L-tryptophan with the pressor responses of the anaesthetized rat to the intravenous injection of clonidine, adrenaline and angiotensin has been studied.2. Pretreatment of rats with L-tryptophan (100 mg/kg) depressed the pressor response to clonidine but had no effect on the responses elicited by adrenaline or angiotensin.3. The L-tryptophan-induced depression of the clonidine response was prevented by pretreating rats with either Rö 44602, carbidopa, BW 172C58, methys-ergide or by pithing.4. Intravenous infusions of serotonin depressed the pressor responses to clonidine, adrenaline and angiotensin in both intact anaesthetized and pithed rats.5. It is concluded that the depressant action of L-tryptophan is dependent on its conversion within the periphery to serotonin. This action is also dependent on or mediated by the sympathetic nervous system.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. The interaction of the biosynthetic precursors of serotonin with the a-adrenoceptor-mediated pressor response to intravenous clonidine was investigated in unanaesthetized rats.2. Pretreatment with 100 mg/kg of either L-tryptophan or 5-hydroxytryptophan (5-HTP) reduced the magnitude of the pressor response elicited by intravenous clonidine (25 μg/kg) to 15% and 11%, respectively, of that observed in control rats.3. The depression by L-tryptophan of the clonidine-induced pressor response could be prevented by pretreatment with either the L-aromatic amino acid de-carboxylase inhibitor Rö-4– 4602 or the serotonin antagonist methysergide.Type of Medium: Electronic ResourceURL: -
18RAMANAMURTHY, P. V. ; BERTSCH, D. L. ; FICHTEL, C. E. ; KANBACH, G. ; KNIFFEN, D. A. ; MAYER-HASSELWANDER, H. A. ; NOLAN, P. L. ; SREEKUMAR, P. ; THOMPSON, D. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
19SCHNEID, E J ; BERTSCH, D L ; FICHTEL, C E ; HARTMAN, R C ; HUNTER, S D ; THOMPSON, D J ; KANBACH, G ; MAYER-HASSELWANDER, H A ; LIN, Y C ; MICHELSON, P F ; NOLAN, P L ; DINGUS, B L ; MONTIGNY, C ; SREEKUMAR, P ; KNIFFEN, D A
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralNotes: The Energetic Gamma-Ray Experiment Telescope (EGRET) has observed gamma-rays bursts with the highest energy gamma-rays and the longest high energy emission to date. EGRET measures the high energy gamma-rays with its large NaI scintillator (1 to 200 MeV) and its spark chamber (30 MeV to 30 GeV). The spark chamber also measures time and arrival directions of individual photons allowing locations for the energetic bursts to be determined. Since the Compton Gamma Ray Observatory launch in 1991, EGRET has observed five bursts in the spark chamber with several having gamma-ray energies grater than 1 GeV. The recording breaking burst, GRB940217, had gamma-rays up to 18 GeV and lasted over 5000 seconds. The results for the energetic bursts are presented. The high energies observed from these gamma-ray bursts set constraints for the burst distances.Type of Medium: Electronic ResourceURL: -
20Nolan, P. D. ; Lutz, B. R. ; Tanaka, P. L. ; Davis, J. E. ; Mullins, C. B.
College Park, Md. : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: High translational energy adsorption of oxygen on the (111) surface of platinum was examined with electron energy loss spectroscopy (EELS) and molecular beam techniques. EEL spectra indicate that over an incident energy range of 0.2–1.37 eV and on a Pt(111) surface held at 77 K, oxygen adsorbs in an associative chemisorbed state—yielding to the dissociated state only after sufficient substrate heating. Simple direct dissociation appears negligible for all incident kinetic energies studied. At near-zero surface coverages, exclusive population of the peroxolike molecular precursor is observed for adsorption at these high translational energies, while both superoxolike and peroxolike forms are detected for low energy adsorption (0.055 eV). This peculiarity represents evidence that translational energy is effective in differentially populating reaction intermediates and provides better quantification of potential energy barriers to dissociation. We estimate the activation barrier for dissociation from the peroxolike precursor to be approximately 0.29 eV. Initial adsorption probability measurements over a wide range of surface temperatures and high incident kinetic energies corroborate a molecular chemisorption mediated mechanism. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: