Search Results - (Author, Cooperation:P. Nilsson)

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  1. 1
    G. B. Ehret ; P. B. Munroe ; K. M. Rice ; M. Bochud ; A. D. Johnson ; D. I. Chasman ; A. V. Smith ; M. D. Tobin ; G. C. Verwoert ; S. J. Hwang ; V. Pihur ; P. Vollenweider ; P. F. O'Reilly ; N. Amin ; J. L. Bragg-Gresham ; A. Teumer ; N. L. Glazer ; L. Launer ; J. H. Zhao ; Y. Aulchenko ; S. Heath ; S. Sober ; A. Parsa ; J. Luan ; P. Arora ; A. Dehghan ; F. Zhang ; G. Lucas ; A. A. Hicks ; A. U. Jackson ; J. F. Peden ; T. Tanaka ; S. H. Wild ; I. Rudan ; W. Igl ; Y. Milaneschi ; A. N. Parker ; C. Fava ; J. C. Chambers ; E. R. Fox ; M. Kumari ; M. J. Go ; P. van der Harst ; W. H. Kao ; M. Sjogren ; D. G. Vinay ; M. Alexander ; Y. Tabara ; S. Shaw-Hawkins ; P. H. Whincup ; Y. Liu ; G. Shi ; J. Kuusisto ; B. Tayo ; M. Seielstad ; X. Sim ; K. D. Nguyen ; T. Lehtimaki ; G. Matullo ; Y. Wu ; T. R. Gaunt ; N. C. Onland-Moret ; M. N. Cooper ; C. G. Platou ; E. Org ; R. Hardy ; S. Dahgam ; J. Palmen ; V. Vitart ; P. S. Braund ; T. Kuznetsova ; C. S. Uiterwaal ; A. Adeyemo ; W. Palmas ; H. Campbell ; B. Ludwig ; M. Tomaszewski ; I. Tzoulaki ; N. D. Palmer ; T. Aspelund ; M. Garcia ; Y. P. Chang ; J. R. O'Connell ; N. I. Steinle ; D. E. Grobbee ; D. E. Arking ; S. L. Kardia ; A. C. Morrison ; D. Hernandez ; S. Najjar ; W. L. McArdle ; D. Hadley ; M. J. Brown ; J. M. Connell ; A. D. Hingorani ; I. N. Day ; D. A. Lawlor ; J. P. Beilby ; R. W. Lawrence ; R. Clarke ; J. C. Hopewell ; H. Ongen ; A. W. Dreisbach ; Y. Li ; J. H. Young ; J. C. Bis ; M. Kahonen ; J. Viikari ; L. S. Adair ; N. R. Lee ; M. H. Chen ; M. Olden ; C. Pattaro ; J. A. Bolton ; A. Kottgen ; S. Bergmann ; V. Mooser ; N. Chaturvedi ; T. M. Frayling ; M. Islam ; T. H. Jafar ; J. Erdmann ; S. R. Kulkarni ; S. R. Bornstein ; J. Grassler ; L. Groop ; B. F. Voight ; J. Kettunen ; P. Howard ; A. Taylor ; S. Guarrera ; F. Ricceri ; V. Emilsson ; A. Plump ; I. Barroso ; K. T. Khaw ; A. B. Weder ; S. C. Hunt ; Y. V. Sun ; R. N. Bergman ; F. S. Collins ; L. L. Bonnycastle ; L. J. Scott ; H. M. Stringham ; L. Peltonen ; M. Perola ; E. Vartiainen ; S. M. Brand ; J. A. Staessen ; T. J. Wang ; P. R. Burton ; M. Soler Artigas ; Y. Dong ; H. Snieder ; X. Wang ; H. Zhu ; K. K. Lohman ; M. E. Rudock ; S. R. Heckbert ; N. L. Smith ; K. L. Wiggins ; A. Doumatey ; D. Shriner ; G. Veldre ; M. Viigimaa ; S. Kinra ; D. Prabhakaran ; V. Tripathy ; C. D. Langefeld ; A. Rosengren ; D. S. Thelle ; A. M. Corsi ; A. Singleton ; T. Forrester ; G. Hilton ; C. A. McKenzie ; T. Salako ; N. Iwai ; Y. Kita ; T. Ogihara ; T. Ohkubo ; T. Okamura ; H. Ueshima ; S. Umemura ; S. Eyheramendy ; T. Meitinger ; H. E. Wichmann ; Y. S. Cho ; H. L. Kim ; J. Y. Lee ; J. Scott ; J. S. Sehmi ; W. Zhang ; B. Hedblad ; P. Nilsson ; G. D. Smith ; A. Wong ; N. Narisu ; A. Stancakova ; L. J. Raffel ; J. Yao ; S. Kathiresan ; C. J. O'Donnell ; S. M. Schwartz ; M. A. Ikram ; W. T. Longstreth, Jr. ; T. H. Mosley ; S. Seshadri ; N. R. Shrine ; L. V. Wain ; M. A. Morken ; A. J. Swift ; J. Laitinen ; I. Prokopenko ; P. Zitting ; J. A. Cooper ; S. E. Humphries ; J. Danesh ; A. Rasheed ; A. Goel ; A. Hamsten ; H. Watkins ; S. J. Bakker ; W. H. van Gilst ; C. S. Janipalli ; K. R. Mani ; C. S. Yajnik ; A. Hofman ; F. U. Mattace-Raso ; B. A. Oostra ; A. Demirkan ; A. Isaacs ; F. Rivadeneira ; E. G. Lakatta ; M. Orru ; A. Scuteri ; M. Ala-Korpela ; A. J. Kangas ; L. P. Lyytikainen ; P. Soininen ; T. Tukiainen ; P. Wurtz ; R. T. Ong ; M. Dorr ; H. K. Kroemer ; U. Volker ; H. Volzke ; P. Galan ; S. Hercberg ; M. Lathrop ; D. Zelenika ; P. Deloukas ; M. Mangino ; T. D. Spector ; G. Zhai ; J. F. Meschia ; M. A. Nalls ; P. Sharma ; J. Terzic ; M. V. Kumar ; M. Denniff ; E. Zukowska-Szczechowska ; L. E. Wagenknecht ; F. G. Fowkes ; F. J. Charchar ; P. E. Schwarz ; C. Hayward ; X. Guo ; C. Rotimi ; M. L. Bots ; E. Brand ; N. J. Samani ; O. Polasek ; P. J. Talmud ; F. Nyberg ; D. Kuh ; M. Laan ; K. Hveem ; L. J. Palmer ; Y. T. van der Schouw ; J. P. Casas ; K. L. Mohlke ; P. Vineis ; O. Raitakari ; S. K. Ganesh ; T. Y. Wong ; E. S. Tai ; R. S. Cooper ; M. Laakso ; D. C. Rao ; T. B. Harris ; R. W. Morris ; A. F. Dominiczak ; M. Kivimaki ; M. G. Marmot ; T. Miki ; D. Saleheen ; G. R. Chandak ; J. Coresh ; G. Navis ; V. Salomaa ; B. G. Han ; X. Zhu ; J. S. Kooner ; O. Melander ; P. M. Ridker ; S. Bandinelli ; U. B. Gyllensten ; A. F. Wright ; J. F. Wilson ; L. Ferrucci ; M. Farrall ; J. Tuomilehto ; P. P. Pramstaller ; R. Elosua ; N. Soranzo ; E. J. Sijbrands ; D. Altshuler ; R. J. Loos ; A. R. Shuldiner ; C. Gieger ; P. Meneton ; A. G. Uitterlinden ; N. J. Wareham ; V. Gudnason ; J. I. Rotter ; R. Rettig ; M. Uda ; D. P. Strachan ; J. C. Witteman ; A. L. Hartikainen ; J. S. Beckmann ; E. Boerwinkle ; R. S. Vasan ; M. Boehnke ; M. G. Larson ; M. R. Jarvelin ; B. M. Psaty ; G. R. Abecasis ; A. Chakravarti ; P. Elliott ; C. M. van Duijn ; C. Newton-Cheh ; D. Levy ; M. J. Caulfield ; T. Johnson
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-09-13
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Africa/ethnology ; Asia/ethnology ; Blood Pressure/*genetics/physiology ; Cardiovascular Diseases/*genetics ; Coronary Artery Disease/genetics ; Europe/ethnology ; Genetic Predisposition to Disease/*genetics ; Genome-Wide Association Study ; Humans ; Hypertension/genetics ; Kidney Diseases/genetics ; Polymorphism, Single Nucleotide/*genetics ; Stroke/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-02-13
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0105-2896
    Electronic ISSN:
    1600-065X
    Topics:
    Medicine
    Published by:
    http://www.wiley.com/wiley-blackwell

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2015-01-24
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alternative Splicing ; Cell Line ; *Databases, Protein ; Female ; Genes ; Genetic Code ; Humans ; Internet ; Male ; Membrane Proteins/genetics/metabolism ; Mitochondrial Proteins/genetics/metabolism ; Neoplasms/genetics/metabolism ; Protein Array Analysis ; Protein Isoforms/genetics/metabolism ; Proteome/genetics/*metabolism ; Tissue Distribution ; Transcription, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Andersen, P. M. ; Nilsson, P. ; Forsgren, L. ; Marklund, S. L.

    Oxford, UK : Blackwell Science Ltd
    Published 1998
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: The Asp90Ala CuZn-superoxide dismutase mutation is associated with amyotrophic lateral sclerosis (ALS) in both homo- and heterozygous form. We analyzed antioxidant enzymes in blood from 44 individuals homozygous and 114 individuals heterozygous for the Asp90Ala mutation as well as 66 blood relatives carrying the wild-type allele only. Erythrocyte CuZn-superoxide dismutase activity was reduced by 9% in the homozygous individuals, confirming previous findings on a smaller cohort. The specific activity of Asp90Ala mutant CuZn-superoxide dismutase in erythrocytes was equal to that of isolated mutant enzyme and slightly higher than that of isolated wild-type enzyme. There was no evidence for the presence of inactive mutant molecules in erythrocytes, and the lower activity is due to the occurrence of fewer active molecules. There were no significant differences between the groups in plasma extracellular superoxide dismutase content, and the erythrocyte glutathione peroxidase activities were virtually identical. Also, there were no differences in these parameters between homozygous individuals with or without ALS. There was no evidence for any association with ALS of a polymorphic extracellular superoxide dismutase mutation, Arg213Gly. The absence of response of the blood antioxidant enzymes to the Asp90Ala CuZn-superoxide dismutase mutation does not support the theory that the ALS-linked CuZn-superoxide dismutase mutations cause disease by increased oxidant stress.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1046/j.1471-4159.1998.70020715.x

    Articles: DFG German National Licenses
  5. 5
    Brorsson, G. ; Olsson, E. ; Nilsson, P. A(ring). ; Claeson, T.

    [S.l.] : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    YBa2Cu3O7−x/insulator/YBa2Cu3O7−x trilayers with a single PrGaO3 (PGO) layer or a SrTiO3 (STO)/PGO multilayer as the insulator were prepared by laser deposition. The PGO layers contained pinholes extending down to the bottom layer, causing superconducting microshorts. The pinholes were eliminated by introducing thin STO films, both as buffer layers and in the PGO itself. Insulation resistivity values of 2×109 Ω cm were measured at 77 K for areas up to 1500 μm2 in these trilayers. For larger areas the insulation decreased by orders of magnitude. This was caused by local disruption of the insulator layer, possibly induced by contaminations or defects in the substrate. The particles observed on the bottom layer were in general continuously covered by the multilayer insulator, and did not affect the insulation. The high-quality insulator layer was found to limit the oxidation of the bottom layer, due to a slower rate of oxygen diffusion. The structure of the STO/PGO layers depended on the thickness of the individual films. Voids started to form in the PGO above a critical thickness of 40 nm. The voids lowered the dielectric constant of the insulator, and a value of 18.5±4.5 was measured at room temperature for a STO/PGO multilayer insulator. The voids could be eliminated by decreasing the thickness of the individual PGO films.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.356436

    Articles: DFG German National Licenses
  6. 6
    Nilsson, P. A(ring). ; Ivanov, Z. G. ; Olsson, H. K. ; Winkler, D. ; Claeson, T. ; Stepantsov, E. A. ; Tzalenchuk, A. Ya.

    [S.l.] : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Josephson junctions and superconducting quantum interference devices (SQUIDs) were made by depositing thin films of YBa2Cu3O7 on bicrystal substrates of Y-ZrO2 and SrTiO3. The critical current density of the junctions at 77 K could be adjusted from 100 to 106 A/cm2 by selecting bicrystals with misorientation angles θ from 45° to 0°. Current-voltage curves from junctions with θ(approximately-greater-than)22° followed the resistively shunted junction model with noise rounding close to the transition temperature. The response of the critical current to magnetic fields was Fraunhofer-like and the width (w) dependence was 1/w2 due to flux focusing effects. Shapiro steps under microwave radiation were observed. SQUIDs based on these junctions had energy resolutions at 77 K down to 8.6×10−30 J/Hz and a 10 Hz flux noise level down to 1.5×10−9 Φ20/Hz at 85 K. A SQUID of the Ketchen design with a flux focusing washer had a magnetic field sensitivity of 15 pT/(square root of)Hz at 77 K. The temperature dependence of the voltage modulation depth close to TC was examined and found to be in agreement with theory [K. Enpuku, Y. Shimomura, and T. Kisu, J. Appl. Phys. 73, 7929 (1993)].
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.356559

    Articles: DFG German National Licenses
  7. 7
    Dantsker, E. ; Tanaka, S. ; Nilsson, P.-A(ring). ; Kleiner, R. ; Clarke, John

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1996
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The spectral density SΦ(f ) of the low-frequency 1/f noise of high transition temperature dc superconducting quantum interference devices (SQUIDs) with narrow linewidths was independent of B0, the magnetic field in which they were cooled, up to a threshold value, about 33 μT in the best case. Above this threshold, which is associated with the entry of flux vortices into the film, the noise increased rapidly. By contrast, for large square washer SQUIDs, SΦ(f ) scaled linearly with B0. Estimates indicate that the 1/f flux noise produced by the pickup loop of a directly coupled magnetometer is negligible. © 1996 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.117831

    Articles: DFG German National Licenses
  8. 8
    Olsson, E. ; Brorsson, G. ; Nilsson, P. A(ring). ; Claeson, T.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Pinholes have been eliminated in trilayers of YBa2Cu3O7−x(YBCO)/PrGaO3(PGO)/YBCO by introducing 13-nm-thick SrTiO3(STO) films in the intermediate PGO film. The STO continuously covers the bottom YBCO layer and promotes a uniform growth of the subsequent PGO films. The individual PGO films are of high quality up to a thickness of about 40 nm where voids start to appear in the films. The voids disrupt the continuity of the subsequent STO and PGO layers. The technique of introducing thin layers that establish the growth of pinhole-free films can be used for other similar multilayer systems that suffer from pinholes between individual films.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.110751

    Articles: DFG German National Licenses
  9. 9
    Brorsson, G. ; Nilsson, P. A(ring). ; Olsson, E. ; Wang, S. Z. ; Claeson, T. ; Löfgren, M.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1992
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    PrGaO3 films were successfully grown by laser deposition at temperatures between 730 and 785 °C. The minimum full width at half maximum value of the (004) x-ray diffraction peak was 0.14°, for films deposited on SrTiO3 substrates at 760 °C. The optimum temperature for deposition of PrGaO3 in YBa2Cu3O7/PrGaO3/YBa2Cu3O7 trilayers was found to be 760 °C. Three distinct layers were observed , and the PrGaO3 exhibited two orientations with respect to the c-axis oriented bottom layer; either the [001] or the [110] direction parallel to the YBa2Cu3O7 c axis. Two orthogonal in-plane orientations were observed for each of these cases. The highest resistivity (at 100 K) of the PrGaO3 layer was 105 Ω cm. Considerable interaction occurred between the PrGaO3 and the YBa2Cu3O7 bottom layer at 785 °C, where the two bottom layers deteriorated.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.107865

    Articles: DFG German National Licenses
  10. 10
    Ivanov, Z. G. ; Nilsson, P. A(ring). ; Winkler, D. ; Alarco, J. A. ; Claeson, T. ; Stepantsov, E. A. ; Tzalenchuk, A. Ya.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1991
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We have studied weak links and dc–SQUIDs made from pulsed laser deposited YBa2Cu3O7−δ thin films on Y–ZrO2 bicrystal substrates. The transport properties of the weak links were studied as a function of the misorientation angle (θ) between the two halves of the bicrystal and an exponential dependence of the weak link critical current density was observed for angles up to 40° at 77 K. Josephson effects with clear microwave and magnetic field responses were observed. An optimum dc–SQUID performance at 77 K was obtained for θ=32°. At this temperature, we achieved a periodic magnetic field response with a modulation depth of 12 μV.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.105783

    Articles: DFG German National Licenses
  11. 11
    Zhang, Y. M. ; Winkler, D. ; Nilsson, P. A(ring). ; Claeson, T.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Josephson flux-flow transistors were made from long YBa2Cu3O7−δ bicrystal grain boundary junctions. A normal metal loop, separated from the junction by an SiO layer, was used as the current control line. The line modulated the critical current, Ic , which for temperatures ≤60 K showed the typical dependence for a long junction, while at higher temperatures the regular small junction modulation was seen. Current gain larger than unity was obtained below 70 K. The current gain increased with the junction length, and varied roughly like (square root of)Ic when decreasing the temperature. A transresistance larger than 5 Ω was obtained at 15 K. Better performance is expected from junctions with higher current densities.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.110836

    Articles: DFG German National Licenses
  12. 12
    Alarco, J. A. ; Brorsson, G. ; Ivanov, Z. G. ; Nilsson, P.-A(ring). ; Olsson, E. ; Löfgren, M.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1992
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    High-quality YBa2Cu3O7−δ films grown on (001) single-crystal Y-ZrO2 substrates by pulsed laser deposition have been studied as a function of substrate temperature using transmission electron microscopy. A transition from epitaxial films to c-axis oriented polycrystalline films was observed at 740 °C. An intermediate, polycrystalline, BaZrO3 layer was formed from a reaction between the film and the substrate. A dominant orientation relationship of [001]YBCO//[001]int. layer//[001]YSZ and [110]YBCO//[110]int. layer//[100]YSZ was observed. The formation of grain boundaries in the films resulted in an increased microwave surface resistance and a decreased critical-current density. The superconducting transition temperature remained fairly constant at about 90 K.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.107779

    Articles: DFG German National Licenses
  13. 13
    Nilsson, P. A(ring). ; Claeson, T. ; Hansen, J. B. ; Kühle, A.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1994
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    The voltage modulation depth of a high Tc dc-SQUID was measured at temperatures close to Tc and compared to a model by Enpuku et al. where the flux noise from the SQUID inductance is taken into account. The device was an YBa2Cu3O7 dc-SQUID made on a bicrystal substrate of SrTiO3. The design was of the Ketchen square-washer type with an inductance of 67 pH. Measurements were made in a temperature interval from 75 to 87 K, where the voltage modulation depth changed from 4.5 to 1.4 μV in close agreement with the model.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.111594

    Articles: DFG German National Licenses
  14. 14
    Edstam, J. ; Nilsson, P-A(ring). ; Stepantsov, E. A. ; Olsson, H. K.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1993
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We have coupled 80–180 GHz oscillations from a HTc Josephson junction onto an on-chip YBa2Cu3O7/SiO/Au microstrip resonator. Efficient coupling was achieved at the resonance frequencies and both resonance frequency and Q value could be measured from the I-V curve. The use of a superconductor in the microstrip gave negligible dispersion (〈4%) from 80 to 180 GHz, whereas the attenuation of 4–8 dB/nm originated mainly from the normal metal groundplane.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.108559

    Articles: DFG German National Licenses
  15. 15
    Olsson, H. K. ; Nilsson, P.-A(ring). ; Ivanov, Z. ; Koch, R. H. ; Stepantsov, E. A. ; Tzalenchuk, A. Ya.

    Woodbury, NY : American Institute of Physics (AIP)
    Published 1992
    Staff View
    ISSN:
    1077-3118
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We report low noise operation of YBa2Cu3O7 SQUIDs superconducting quantum interference devices using Josephson junctions grown on bicrystal substrates of (Y)ZrO2. Energy sensitivities measured at 10 Hz (Sε=4.5×10−29 J/Hz) were to our knowledge lower than previously reported for a YBa2Cu3O7 SQUID with practical loop size (∼40 μm). The 1/f part of the voltage noise reached a maximum at 85 K where the noise spectrum was essentially white. The 1/f noise increased both at lower temperatures due to increased critical current fluctuations (∼Ibias2.2) and at higher temperatures, where the flux noise from the film produces a peak below Tc(=89 K).
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1063/1.107769

    Articles: DFG German National Licenses
  16. 16
    Thorsson, O. ; Leander, P. ; Lilja, B. ; Nilsson, P. ; Obrant, K. J. ; Westlin, N.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1600-0838
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Sports Science
    Notes:
    A standardized trauma was inflicted to the lateral side of the calf muscle of 12 New Zealand rabbits, creating a muscle hematoma without external bleeding. The acute hematoma was evaluated within 3 h with radionuclide imaging of red blood cells labelled with 99mTc pertechnetate, ultrasonography and magnetic resonance imaging (MRI). The results were compared with the total volume of the hematomas as calculated from histological preparations of each injured muscle. Scintigraphy and T2-weighted MRI accurately detected all hematomas but the calculated volume did not significantly correlate with histology. T1-weighted MRI did not detect the hematomas. Ultrasonography detected all hematomas and also accurately evaluated the volume. In conclusion, scintigraphy, MR imaging and ultrasonography are all sensitive enough to detect an acute muscle injury, but in this investigation only ultrasonography accurately quantified the volume of the hematoma.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0838.1993.tb00371.x

    Articles: DFG German National Licenses
  17. 17
    HANSSON, LARS-ANDERS ; BRÖNMARK, CHRISTER ; ANDERS NILSSON, P ; ÅBJÖRNSSON, KAJSA

    Oxford, UK : Blackwell Science Ltd
    Published 2005
    Staff View
    ISSN:
    1365-2427
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    1. Wetland ecosystems may, besides having considerable economical value, increase landscape biodiversity and function as traps for nutrients from land to freshwater- and marine systems. As a result of these features, wetlands are nowadays often protected and restored, and many countries have even initiated wetland construction programmes.2. In the present study, we aim at increasing the knowledge on how to improve the design of a wetland with respect to both biodiversity and nutrient retention, by analysing physical, chemical and biological features of a large set of constructed wetlands.3. Our results show that a combination of the wetland features, namely shallow depth, large surface area and high shoreline complexity are likely to provide a high biodiversity of birds, benthic invertebrates and macrophytes and to have high nitrogen retention, whereas a small, deep wetland is likely to be more efficient in phosphorus retention, but less valuable in terms of biodiversity.4. Hence, among the features used to design new wetlands, area, depth and shoreline complexity have fundamental, and sometimes conflicting, effects on nutrient retention and biodiversity. This means that there are, within limits, possibilities to direct the ecosystem function of a specific wetland in desired directions.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2427.2005.01352.x

    Articles: DFG German National Licenses
  18. 18
    REIMERS, J. ; WOGENSEN, L. D. ; WELINDER, B. ; HEJNÆS, K. R. ; POULSEN, S. S. ; NILSSON, P. ; NERUP, J.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Based upon in vivo rat experiments it was recently suggested that interleukin I in the circulation may be implicated in the initial events of β-cell destruction leading to insulin-dependent diabetes mellitus (IDDM) in humans. The aim of the present study was to estimate half-lives of distribution and elimination phases (T1/2β) of human recombinant interleukin 1β(rIL-1β), and its tissue distribution and cellular localization by means of mono-labelled, biologically active 125I-rIL-1β. After intravenous (iv.) injection, 125I-rIL-1β was eliminated from the circulation with a T1/2α of 2.9 min and a T1/2β of 41.1 min. The central and peripheral volume of distribution was 20.7 and 19.1 ml/rat, respectively, and the metabolic clearance rate was 16.9 ml/min/kg. The kidney and liver showed the highest accumulation of tracer, and autoradiography demonstrated that 125I-rIL-1β was localized 10 the proximal tubules in the kidney and to the hepatocytes in the liver. Furthermore, grains were localized to the islets of Langerhans in the pancreas. Tracer-bound proteins corresponding to intact 125I-rIL-1β were found in the circulation after i.v., intraperitoneal (i,p.) and subcutaneous (s.c.) injections, as demonstrated by high performance size exclusion chromatography. trichloracetic acid precipitation and SDS PAGE until 5h after tracer injection. Pre-treatment with “cold” rIL-1β enhanced degradation of a subsequent injection of tracer. The route of administration was of importance for the biological effects of rIL-1β as demonstrated by a reduced food intake, increased rectal temperature and blood glucose after s.c. injection of rIL-1β compared with i.p. The present demonstration of intact rIL-1β in the circulation and the islets of Langerhans supports the hypothesis that systemic IL-1β may be involved in the initial 1β-cell destruction leading to IDDM in humans.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1991.tb01583.x

    Articles: DFG German National Licenses
  19. 19
    Thorsson, O. ; Lilja, B. ; Nilsson, P. ; Westlin, N.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1997
    Staff View
    ISSN:
    1600-0838
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Sports Science
    Notes:
    In a prospective, non-randomized study 40 athletes with contusion or distension injuries to the thigh or the calf muscle were followed with tests of range of motion (ROM) of knee or ankle joint, test of serum creatine kinase (CK) and ultrasonography of the injury until completely recovered. An experimental group of 19 injuries where subjects received treatment with application of a maximum compression bandage within 5 min (mean=2 min) of the injury was compared to a control group of 21 injuries where subjects were treated with rest and elevation only, and in some cases non-maximum compression after 10–30 min. No significant differences were noted with respect to time to complete subjective recovery, ultrasonic size of the injury or time to normal findings on ultrasound between treatment and control groups. Strain injuries, although showing a tendency to be smaller in size, took a longer time to complete recovery than contusion injuries (mean±SD=26±22 days and 19±9 days, respectively, P=0.02). Diagnostic CK values and reductions in ROM were not correlated to the severity of the trauma, while ROM showed weak correlation to the sonographically measured size of the hematoma (r=0.42; P〈0.01). Injuries displaying a circumscript anechoic, low-echogenic or mixed lesion at the diagnostic ultrasound investigation normalized more slowly (P=0.001) and took longer to complete recovery (P=0.001) than injuries with diffuse hyperechogenic lesions. We conclude that in this study the application of a maximum compression bandage within 5 min of a muscle trauma did not significantly reduce the size of the hematoma nor significantly shorten the time to complete subjective recovery compared with no immediate treatment. The diagnostic ultrasound investigation was valuable in predicting the severity of the trauma.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-0838.1997.tb00137.x

    Articles: DFG German National Licenses
  20. 20
    Göransson, M. ; Forsman, K. ; Nilsson, P. ; Uhlin, B. E.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    Transcription of the genes encoding pilus-adhesin of serotype F13 in digalactoside-binding Escherichia coli required activation by the cAMP-CRP complex. Analysis of protein-DNA interaction in vitro showed that CRP bound in a cAMP-dependent manner to a sequence located 0.2 kb upstream of the point of transcription initiation of the pilus subunit operon. The cAMP-CRP activation included, in addition to the main pilus operon, the oppositely oriented operon encoding the Papl regulatory protein. Furthermore, the auto-regulatory product of the promoter-proximal gene (papB) in the pilus subunit operon was found to stimulate the papl transcriptional unit. Thus the cAMP-CRP complex and PapB might act in concert and indirectly promote pili synthesis by stimulating expression of the Papl positive regulator. The results of trans complementation experiments and analyses using lacZ operon fusion derivatives showed that the cAMP-CRP activation also operated directly in cis on the pilus subunit operon. The region containing the CRP binding site appeared to function as an upstream activating sequence since deletion abolished expression even when the pap regulatory proteins Papl and PapB were supplied in trans. The implications for possible mechanisms of transcriptional activation by the cAMP-CRP complex at this novel location between the two oppositely oriented operons are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2958.1989.tb00141.x

    Articles: DFG German National Licenses